Ellenberger, David

[["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Stork, Lidia"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Lucchinetti, C."],["dc.contributor.author","Brück, Wolfgang"],["dc.contributor.author","Metz, Imke"],["dc.date.accessioned","2018-11-07T10:08:49Z"],["dc.date.available","2018-11-07T10:08:49Z"],["dc.date.issued","2016"],["dc.description.sponsorship","Teva Pharma; Biogen; Novartis; Genzyme"],["dc.format.extent","367"],["dc.identifier.isi","000383267201480"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39540"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Apheresis therapy in multiple sclerosis patients with histopathologically classified immunopathological patterns"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","587"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Journal of Clinical Investigation"],["dc.bibliographiccitation.lastpage","593"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Rommer, Paulus S."],["dc.contributor.author","Buckow, Karoline"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Pitschnau-Michel, Dorothea"],["dc.contributor.author","Fuge, Jan"],["dc.contributor.author","Stueve, Olaf"],["dc.contributor.author","Zettl, Uwe K."],["dc.date.accessioned","2018-11-07T09:56:47Z"],["dc.date.available","2018-11-07T09:56:47Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundMultiple Sclerosis is the most common disease in young adults affecting the central nervous system. Disease may progress with acute attacks (relapsing MS) or continuously (progressive MS). Glucocorticosteroids are used in the treatment of acute attacks. The aim of this study was to analyse characteristics of patients with MS, and their influence on current treatment patterns of relapses with glucocorticosteroids. DesignIn 2001, the German National MS Society initiated the German MS-Registry. Patients with relapsing MS were included (n=5106) from this registry. Logistic regression models were used to detect trends over time. The likelihood of administration of steroids is modelled in dependence of calendar year and in dependence to confounders in treatment conditions. The sample size allows that odds ratios can be detected with a power of 90% (alpha=005). ResultsAdministration of glucocorticosteroids was influenced by EDSS (P<00001), age (P<00001) and disease duration (P<00001). Therapy administration in an outpatient setting was more likely in patients with higher EDSS (P<00001) and longer disease duration (P<00001). The utilization of glucocorticosteroids increased with higher EDSS for all relapsing patients. Interestingly, all overutilization of glucocorticosteroids decreased over time and was accompanied by a steadily increased administration of emergent therapeutics. Although there are about 70% of registered patients with relapsing MS on immune-modulatory treatment, almost 60% of them received glucocorticosteroids for treatment of relapses. ConclusionsTreatment patterns with glucocorticosteroids in patients with MS are influenced mainly by EDSS and disease duration. The decline in the utilization of glucocorticosteroids is accompanied by an increase in natalizumab treatment."],["dc.description.sponsorship","Teva Pharmaceuticals"],["dc.identifier.doi","10.1111/eci.12450"],["dc.identifier.isi","000354645200007"],["dc.identifier.pmid","25868705"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37036"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1365-2362"],["dc.relation.issn","0014-2972"],["dc.title","Patients characteristics influencing the longitudinal utilization of steroids in multiple sclerosis - an observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1641"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","1652"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Rommer, Paulus Stefan"],["dc.contributor.author","Eichstädt, Kerstin"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Haas, Judith"],["dc.contributor.author","Kleinschnitz, Christoph"],["dc.contributor.author","Pöhlau, Dieter"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Stahmann, Alexander"],["dc.contributor.author","Zettl, Uwe Klaus"],["dc.date.accessioned","2020-12-10T18:38:31Z"],["dc.date.available","2020-12-10T18:38:31Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1177/1352458518799580"],["dc.identifier.eissn","1477-0970"],["dc.identifier.issn","1352-4585"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77349"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Symptomatology and symptomatic treatment in multiple sclerosis: Results from a nationwide MS registry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","92"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Blood Purification"],["dc.bibliographiccitation.lastpage","97"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Koziolek, Michael J."],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Sigler, Matthias"],["dc.contributor.author","Huppke, Brenda"],["dc.contributor.author","Gärtner, Jutta"],["dc.contributor.author","Mueller, Gerhard-Anton"],["dc.contributor.author","Huppke, Peter"],["dc.contributor.author","Mühlhausen, Johannes"],["dc.date.accessioned","2017-09-07T11:48:19Z"],["dc.date.available","2017-09-07T11:48:19Z"],["dc.date.issued","2013"],["dc.description.abstract","Background/Aims: In adults, plasma exchange (PE) has been shown to be an efficient treatment for severe relapses of acute inflammatory CNS demyelinating diseases. The aim of this study was to evaluate the safety and efficacy of this treatment in pediatric patients. Methods: We retrospectively analyzed a single-center cohort of pediatric patients with inflammatory CNS demyelinating disorders who underwent apheresis between 2007 and 2011. Results: Ten patients (mean age: 11.6 +/- 3.4 years) with an acute relapse of multiple sclerosis (n = 5), neuromyelitis optica (n = 2) or acute disseminated encephalomyelitis were included. All received methylprednisolone prior to treatment with either PE (n = 5) or immunoadsorption (n = 5). Apheresis-related side effects were either self-limiting or easily managed. EDSS (Expanded Disability Status Scale) improved in 7 of 8 patients during apheresis and in all patients within 30 days from a median of 7.5 to 1 (p < 0.01). The visual acuity initially worsened during the procedure in 3 of 7 affected eyes (mean 0.09), but improved in all at follow-up (mean: 0.5; p = 0.008). Conclusions: Apheresis was well tolerated and associated with a favorable outcome in all pediatric patients similar to reports in adults. Copyright (C) 2013 S. Karger AG, Basel"],["dc.identifier.doi","10.1159/000354077"],["dc.identifier.gro","3142409"],["dc.identifier.isi","000328188600005"],["dc.identifier.pmid","24021839"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10815"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7963"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","S. Karger AG"],["dc.relation.eissn","1421-9735"],["dc.relation.issn","0253-5068"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Therapeutic Apheresis in Pediatric Patients with Acute CNS Inflammatory Demyelinating Disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","173"],["dc.bibliographiccitation.journal","Multiple Sclerosis and Related Disorders"],["dc.bibliographiccitation.lastpage","174"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Eichstädt, Kerstin"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Haas, Judith"],["dc.contributor.author","Kleinschnitz, Christoph"],["dc.contributor.author","Pöhlau, Dieter"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Stahmann, Alexander"],["dc.contributor.author","Zettl, Uwe K"],["dc.contributor.author","Rommer, Paulus S"],["dc.date.accessioned","2020-12-10T15:20:23Z"],["dc.date.available","2020-12-10T15:20:23Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.msard.2018.07.040"],["dc.identifier.issn","2211-0348"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72654"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Decreasing longitudinal use of glucocorticosteroids in multiple sclerosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e204"],["dc.bibliographiccitation.firstpage","e204"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neurology: Neuroimmunology & Neuroinflammation"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Metz, Imke"],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Pache, Florence"],["dc.contributor.author","Stork, Lidia"],["dc.contributor.author","Ringelstein, Marius"],["dc.contributor.author","Aktas, Orhan"],["dc.contributor.author","Jarius, Sven"],["dc.contributor.author","Wildemann, Brigitte"],["dc.contributor.author","Dihazi, Hassan"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Brück, Wolfgang"],["dc.contributor.author","Ruprecht, Klemens"],["dc.contributor.author","Paul, Friedemann"],["dc.date.accessioned","2020-12-10T18:41:40Z"],["dc.date.available","2020-12-10T18:41:40Z"],["dc.date.issued","2016"],["dc.description.abstract","To assess in an observational study whether serum peptide antibody reactivities may distinguish aquaporin-4 (AQP4) antibody (Ab)-positive and -negative neuromyelitis optica spectrum disorders (NMOSD) and relapsing-remitting multiple sclerosis (RRMS)."],["dc.identifier.doi","10.1212/NXI.0000000000000204"],["dc.identifier.eissn","2332-7812"],["dc.identifier.pmid","26894206"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12922"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77646"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2332-7812"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","397"],["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.lastpage","398"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Hummel, H. M."],["dc.contributor.author","Huppke, Peter"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Gaertner, J."],["dc.date.accessioned","2018-11-07T09:35:28Z"],["dc.date.available","2018-11-07T09:35:28Z"],["dc.date.issued","2014"],["dc.identifier.isi","000354441300914"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32390"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.eventlocation","Boston, MA"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Sex related differences in T2 lesion load in pediatric multiple sclerosis patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Multiple Sclerosis Journal"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Sterz, C."],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Meissner, H."],["dc.contributor.author","Gusowski, K."],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2018-11-07T09:51:59Z"],["dc.date.available","2018-11-07T09:51:59Z"],["dc.date.issued","2015"],["dc.format.extent","122"],["dc.identifier.isi","000365729400209"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36022"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.publisher.place","London"],["dc.relation.conference","31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","1477-0970"],["dc.relation.issn","1352-4585"],["dc.title","Development and validation of employment-specific assessment instruments in German MS patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","436"],["dc.bibliographiccitation.issue","07"],["dc.bibliographiccitation.journal","Fortschritte der Neurologie · Psychiatrie"],["dc.bibliographiccitation.lastpage","450"],["dc.bibliographiccitation.volume","88"],["dc.contributor.author","Flachenecker, Peter"],["dc.contributor.author","Eichstädt, Kerstin"],["dc.contributor.author","Berger, Klaus"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Haas, Judith"],["dc.contributor.author","Kleinschnitz, Christoph"],["dc.contributor.author","Pöhlau, Dieter"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Stahmann, Alexander"],["dc.contributor.author","Zettl, Uwe K."],["dc.date.accessioned","2021-04-14T08:25:41Z"],["dc.date.available","2021-04-14T08:25:41Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1055/a-0985-4124"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81707"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1439-3522"],["dc.relation.issn","0720-4299"],["dc.title","Multiple Sklerose in Deutschland: aktualisierte Auswertungen des MS-Registers der DMSG 2014–2018"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","558"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Biometrical Journal"],["dc.bibliographiccitation.lastpage","574"],["dc.bibliographiccitation.volume","63"],["dc.contributor.author","Ellenberger, David"],["dc.contributor.author","Lausen, Berthold"],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2021-04-14T08:32:23Z"],["dc.date.available","2021-04-14T08:32:23Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1002/bimj.201900273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83900"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1521-4036"],["dc.relation.issn","0323-3847"],["dc.title","Exact change point detection with improved power in small‐sample binomial sequences"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]