Schweizer, Renate

[["dc.bibliographiccitation.journal","Frontiers in Human Neuroscience"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schweizer, Renate"],["dc.date.accessioned","2022-10-06T13:26:45Z"],["dc.date.available","2022-10-06T13:26:45Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.3389/fnhum.2014.00658"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115159"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1662-5161"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Individual fMRI maps of all phalanges and digit bases of all fingers in human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2138"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","2143"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2022-10-06T13:33:18Z"],["dc.date.available","2022-10-06T13:33:18Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1016/j.neuroimage.2011.03.038"],["dc.identifier.pii","S1053811911003168"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115600"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","1053-8119"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Functional MRI indicates consistent intra-digit topographic maps in the little but not the index finger within the human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","189"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Restorative Neurology and Neuroscience"],["dc.bibliographiccitation.lastpage","197"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","von Lewinski, Friederike"],["dc.contributor.author","Hofer, Sabine"],["dc.contributor.author","Kaus, Juergen"],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Rothkegel, Holger"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Liebetanz, David"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:35:28Z"],["dc.date.available","2018-11-07T08:35:28Z"],["dc.date.issued","2009"],["dc.description.abstract","Purpose: EMG-triggered electrostimulation (EMG-ES) may improve the motor performance of affected limbs of hemiparetic stroke patients even in the chronic stage. This study was designed to characterize cortical activation changes following intensified EMG-ES in chronic stroke patients and to identify predictors for successful rehabilitation depending on disease severity. Methods: We studied 9 patients with severe residual hemiparesis, who underwent 8 weeks of daily task-orientated multi-channel EMG-ES of the paretic arm. Before and after treatment, arm function was evaluated clinically and cortical activation patterns were assessed with functional MRI (fMRI) and/or transcranial magnetic stimulation (TMS). Results: As response to therapy, arm function improved in a subset of patients with more capacity in less affected subjects, but there was no significant gain for those with Box & Block test values below 4 at inception. The clinical improvement, if any, was accompanied by an ipsilesional increase in the sensorimotor cortex (SMC) activation area in fMRI and enhanced intracortical facilitation (ICF) as revealed by paired TMS. The SMC activation change in fMRI was predicted by the presence or absence of motor-evoked potentials (MEPs) on the affected side. Conclusions: The present findings support the notion that intensified EMG-ES may improve the arm function in individual chronic hemiparetic stroke patients but not in more severely impaired individuals. Functional improvements are paralleled by increased ipsilesional SMC activation and enhanced ICF supporting neuroplasticity as contributor to rehabilitation. The clinical score at inception and the presence of MEPs have the best predictive potential."],["dc.identifier.doi","10.3233/RNN-2009-0469"],["dc.identifier.isi","000267763500004"],["dc.identifier.pmid","19531874"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18074"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Ios Press"],["dc.relation.issn","0922-6028"],["dc.title","Efficacy of EMG-triggered electrical arm stimulation in chronic hemiparetic stroke patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","35"],["dc.bibliographiccitation.journal","Frontiers in Neuroanatomy"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Helms, Gunther"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2019-07-09T11:41:12Z"],["dc.date.available","2019-07-09T11:41:12Z"],["dc.date.issued","2014"],["dc.description.abstract","In 1860 and 1862, the German physiologist Wagner published two studies, in which he compared the cortical surfaces of brain specimens. This provided the first account of a rare anatomical variation - bridges across the central sulci in both hemispheres connecting the forward and backward facing central convolutions in one of the brains. The serendipitous rediscovery of the preserved historic brain specimen in the collections at Göttingen University, being mistaken as the brain of the mathematician C.F. Gauss, allowed us to further investigate the morphology of the bridges Wagner had described with magnetic resonance imaging (MRI). On the historic lithograph, current photographs and MRI surface reconstructions of the brain, a connection across the central sulcus can only be seen in the left hemisphere. In the right hemisphere, contrary to the description of Wagner, a connecting structure is only present across the post-central sulcus. MRI reveals that the left-hemispheric bridge extends into the depth of the sulcus, forming a transverse connection between the two opposing gyri. This rare anatomical variation, generally not associated with neurological symptoms, would nowadays be categorized as a divided central sulcus. The left-hemispheric connection seen across the post-central sulcus, represents the very common case of a segmented post-central sulcus. MRI further disclosed a connection across the right-hemispheric central sulcus, which terminates just below the surface of the brain and is therefore not depicted on the historical lithography. This explains the apparent inconsistency between the bilateral description of bridges across the central sulci and the unilateral appearance on the brain surface. The results are discussed based on the detailed knowledge of anatomists of the late 19th century, who already recognized the divided central sulcus as an extreme variation of a deep convolution within the central sulcus."],["dc.identifier.doi","10.3389/fnana.2014.00035"],["dc.identifier.pmid","24904304"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11803"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58369"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1662-5129"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Revisiting a historic human brain with magnetic resonance imaging - the first description of a divided central sulcus."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","493174"],["dc.bibliographiccitation.journal","Gastroenterology Research and Practice"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Zhang, S."],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:46:32Z"],["dc.date.available","2018-11-07T09:46:32Z"],["dc.date.issued","2014"],["dc.description.abstract","The aim of this study was to assess the physiology of normal swallowing using recent advances in real-time magnetic resonance imaging (MRI). Therefore ten young healthy subjects underwent real-time MRI and flexible endoscopic evaluations of swallowing (FEES) with thickened pineapple juice as oral contrast bolus. MRI movies were recorded in sagittal, coronal, and axial orientations during successive swallows at about 25 frames per second. Intermeasurement variation was analyzed and comparisons between real-time MRI and FEES were performed. Twelve distinct swallowing events could be quantified by real-time MRI (start time, end time, and duration). These included five valve functions: oro-velar opening, velo-pharyngeal closure, glottal closure, epiglottic retroflexion, and esophageal opening; three bolus transports: oro-velar transit, pharyngeal delay, pharyngeal transit; and four additional events: laryngeal ascent, laryngeal descent, vallecular, and piriform sinus filling and pharyngeal constriction. Repetitive measurements confirmed the general reliability of the MRI method with only two significant differences for the start times of the velo-pharyngeal closure (t(8) = -2.4, P <= 0.046) and laryngeal ascent (t(8) = -2.6, P <= 0.031). The duration of the velo-pharyngeal closure was significantly longer in real-time MRI compared to FEES (t(8) = -3.3, P <= 0.011). Real-time MRI emerges as a simple, robust, and reliable tool for obtaining comprehensive functional and anatomical information about the swallowing process."],["dc.identifier.doi","10.1155/2014/493174"],["dc.identifier.isi","000331937800001"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11686"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34894"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Hindawi Publishing Corporation"],["dc.relation.issn","1687-630X"],["dc.relation.issn","1687-6121"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","On the Physiology of Normal Swallowing as Revealed by Magnetic Resonance Imaging in Real Time"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e269"],["dc.bibliographiccitation.journal","Brain: A Journal of Neurology"],["dc.bibliographiccitation.volume","137"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Wittmann, Axel D."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:42:00Z"],["dc.date.available","2018-11-07T09:42:00Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1093/brain/awt296"],["dc.identifier.isi","000333260900005"],["dc.identifier.pmid","24163274"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33859"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1460-2156"],["dc.relation.issn","0006-8950"],["dc.title","A rare anatomical variation newly identifies the brains of CF Gauss and CH Fuchs in a collection at the University of Gottingen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2155"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","2163"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schweizer, Renate"],["dc.date.accessioned","2018-11-07T09:52:37Z"],["dc.date.available","2018-11-07T09:52:37Z"],["dc.date.issued","2015"],["dc.description.abstract","Individual intra-digit somatotopy of all phalanges of the middle and little finger of the right and left hand was studied by functional magnetic resonance imaging in 12 healthy subjects. Phalanges were tactilely stimulated and activation in BA3b of the human primary somatosensory cortex could be observed for each individual phalanx. Activation peaks were further analysed using the Direction/Order (DiOr) method, which identifies somatotopy, if a significantly high number of subjects exhibit ordered distal-to-proximal phalanx representions along a similar direction. Based on DiOr, ordered and similar-direction-aligned intra-digit maps across subjects were found at the left hand for the little and middle finger and at the right hand for the little finger. In these digits the proximal phalanges were represented more medially along the course of the central sulcus than the distal phalanges. This is contrasted by the intra-digit maps for the middle finger of the right hand, which showed larger inter-subject variations of phalanx alignments without a similar within-digit representation across subjects. As all subjects were right-handed and as the middle finger of the dominant hand probably plays a more individual role in everyday tactile performance than the little finger of the right hand and all left-hand digits, the observed variation might reflect a functional somatotopy based on individual use of that particular digit at the dominant hand."],["dc.identifier.doi","10.1111/ejn.12978"],["dc.identifier.isi","000360854900005"],["dc.identifier.pmid","26061413"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36168"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1460-9568"],["dc.relation.issn","0953-816X"],["dc.title","Individual left-hand and right-hand intra-digit representations in human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]