Now showing 1 - 5 of 5
  • 2014Journal Article
    [["dc.bibliographiccitation.journal","Frontiers in Human Neuroscience"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schweizer, Renate"],["dc.date.accessioned","2022-10-06T13:26:45Z"],["dc.date.available","2022-10-06T13:26:45Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.3389/fnhum.2014.00658"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115159"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1662-5161"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Individual fMRI maps of all phalanges and digit bases of all fingers in human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2011Journal Article
    [["dc.bibliographiccitation.firstpage","2138"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","2143"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2022-10-06T13:33:18Z"],["dc.date.available","2022-10-06T13:33:18Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1016/j.neuroimage.2011.03.038"],["dc.identifier.pii","S1053811911003168"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115600"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","1053-8119"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Functional MRI indicates consistent intra-digit topographic maps in the little but not the index finger within the human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2009Journal Article
    [["dc.bibliographiccitation.firstpage","189"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Restorative Neurology and Neuroscience"],["dc.bibliographiccitation.lastpage","197"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","von Lewinski, Friederike"],["dc.contributor.author","Hofer, Sabine"],["dc.contributor.author","Kaus, Juergen"],["dc.contributor.author","Merboldt, Klaus-Dietmar"],["dc.contributor.author","Rothkegel, Holger"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Liebetanz, David"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:35:28Z"],["dc.date.available","2018-11-07T08:35:28Z"],["dc.date.issued","2009"],["dc.description.abstract","Purpose: EMG-triggered electrostimulation (EMG-ES) may improve the motor performance of affected limbs of hemiparetic stroke patients even in the chronic stage. This study was designed to characterize cortical activation changes following intensified EMG-ES in chronic stroke patients and to identify predictors for successful rehabilitation depending on disease severity. Methods: We studied 9 patients with severe residual hemiparesis, who underwent 8 weeks of daily task-orientated multi-channel EMG-ES of the paretic arm. Before and after treatment, arm function was evaluated clinically and cortical activation patterns were assessed with functional MRI (fMRI) and/or transcranial magnetic stimulation (TMS). Results: As response to therapy, arm function improved in a subset of patients with more capacity in less affected subjects, but there was no significant gain for those with Box & Block test values below 4 at inception. The clinical improvement, if any, was accompanied by an ipsilesional increase in the sensorimotor cortex (SMC) activation area in fMRI and enhanced intracortical facilitation (ICF) as revealed by paired TMS. The SMC activation change in fMRI was predicted by the presence or absence of motor-evoked potentials (MEPs) on the affected side. Conclusions: The present findings support the notion that intensified EMG-ES may improve the arm function in individual chronic hemiparetic stroke patients but not in more severely impaired individuals. Functional improvements are paralleled by increased ipsilesional SMC activation and enhanced ICF supporting neuroplasticity as contributor to rehabilitation. The clinical score at inception and the presence of MEPs have the best predictive potential."],["dc.identifier.doi","10.3233/RNN-2009-0469"],["dc.identifier.isi","000267763500004"],["dc.identifier.pmid","19531874"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18074"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Ios Press"],["dc.relation.issn","0922-6028"],["dc.title","Efficacy of EMG-triggered electrical arm stimulation in chronic hemiparetic stroke patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.artnumber","e269"],["dc.bibliographiccitation.journal","Brain: A Journal of Neurology"],["dc.bibliographiccitation.volume","137"],["dc.contributor.author","Schweizer, Renate"],["dc.contributor.author","Wittmann, Axel D."],["dc.contributor.author","Frahm, Jens"],["dc.date.accessioned","2018-11-07T09:42:00Z"],["dc.date.available","2018-11-07T09:42:00Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1093/brain/awt296"],["dc.identifier.isi","000333260900005"],["dc.identifier.pmid","24163274"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33859"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1460-2156"],["dc.relation.issn","0006-8950"],["dc.title","A rare anatomical variation newly identifies the brains of CF Gauss and CH Fuchs in a collection at the University of Gottingen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","2155"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","2163"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Schweisfurth, Meike A."],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schweizer, Renate"],["dc.date.accessioned","2018-11-07T09:52:37Z"],["dc.date.available","2018-11-07T09:52:37Z"],["dc.date.issued","2015"],["dc.description.abstract","Individual intra-digit somatotopy of all phalanges of the middle and little finger of the right and left hand was studied by functional magnetic resonance imaging in 12 healthy subjects. Phalanges were tactilely stimulated and activation in BA3b of the human primary somatosensory cortex could be observed for each individual phalanx. Activation peaks were further analysed using the Direction/Order (DiOr) method, which identifies somatotopy, if a significantly high number of subjects exhibit ordered distal-to-proximal phalanx representions along a similar direction. Based on DiOr, ordered and similar-direction-aligned intra-digit maps across subjects were found at the left hand for the little and middle finger and at the right hand for the little finger. In these digits the proximal phalanges were represented more medially along the course of the central sulcus than the distal phalanges. This is contrasted by the intra-digit maps for the middle finger of the right hand, which showed larger inter-subject variations of phalanx alignments without a similar within-digit representation across subjects. As all subjects were right-handed and as the middle finger of the dominant hand probably plays a more individual role in everyday tactile performance than the little finger of the right hand and all left-hand digits, the observed variation might reflect a functional somatotopy based on individual use of that particular digit at the dominant hand."],["dc.identifier.doi","10.1111/ejn.12978"],["dc.identifier.isi","000360854900005"],["dc.identifier.pmid","26061413"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36168"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1460-9568"],["dc.relation.issn","0953-816X"],["dc.title","Individual left-hand and right-hand intra-digit representations in human primary somatosensory cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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