Ebert, Antje Dagmar

[["dc.bibliographiccitation.journal","Biological Chemistry"],["dc.contributor.author","Ebert, Antje"],["dc.date.accessioned","2022-01-11T14:07:59Z"],["dc.date.available","2022-01-11T14:07:59Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1515/hsz-2021-0432"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97908"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","1437-4315"],["dc.relation.issn","1431-6730"],["dc.title","Signal transduction in health and disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","113"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Biological Chemistry"],["dc.bibliographiccitation.lastpage","121"],["dc.bibliographiccitation.volume","402"],["dc.contributor.author","Malkovskiy, Andrey V."],["dc.contributor.author","Ignatyeva, Nadezda"],["dc.contributor.author","Dai, Yuanyuan"],["dc.contributor.author","Hasenfuss, Gerd"],["dc.contributor.author","Rajadas, Jayakumar"],["dc.contributor.author","Ebert, Antje"],["dc.date.accessioned","2021-04-14T08:29:54Z"],["dc.date.available","2021-04-14T08:29:54Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1515/hsz-2020-0212"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83028"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1437-4315"],["dc.relation.issn","1431-6730"],["dc.title","Integrated Ca 2+ flux and AFM force analysis in human iPSC-derived cardiomyocytes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Pflügers Archiv - European Journal of Physiology"],["dc.contributor.author","Pan, Ziwei"],["dc.contributor.author","Ebert, Antje"],["dc.contributor.author","Liang, Ping"],["dc.date.accessioned","2021-06-01T10:49:13Z"],["dc.date.available","2021-06-01T10:49:13Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00424-020-02486-y"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86209"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/373"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | A12: Alternative molekulare Signaltransduktionswege durch Kardiomyopathie-verursachende Troponin-Mutationen"],["dc.relation.eissn","1432-2013"],["dc.relation.issn","0031-6768"],["dc.relation.workinggroup","RG Ebert (Cardiovascular Cell Biology and Systems Medicine)"],["dc.title","Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","overview_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","720"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Circulation Research"],["dc.bibliographiccitation.lastpage","730"],["dc.bibliographiccitation.volume","117"],["dc.contributor.author","Riegler, Johannes"],["dc.contributor.author","Tiburcy, Malte"],["dc.contributor.author","Ebert, Antje"],["dc.contributor.author","Tzatzalos, Evangeline"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Abilez, Oscar J."],["dc.contributor.author","Shen, Qi"],["dc.contributor.author","Kooreman, Nigel G."],["dc.contributor.author","Neofytou, Evgenios"],["dc.contributor.author","Chen, Vincent C."],["dc.contributor.author","Wang, Mouer"],["dc.contributor.author","Meyer, Tim"],["dc.contributor.author","Tsao, Philip S."],["dc.contributor.author","Connolly, Andrew J."],["dc.contributor.author","Couture, Larry A."],["dc.contributor.author","Gold, Joseph D."],["dc.contributor.author","Zimmermann, Wolfram-Hubertus"],["dc.contributor.author","Wu, Joseph C."],["dc.date.accessioned","2017-09-07T11:43:32Z"],["dc.date.available","2017-09-07T11:43:32Z"],["dc.date.issued","2015"],["dc.description.abstract","Rationale: Tissue engineering approaches may improve survival and functional benefits from human embryonic stem cell-derived cardiomyocyte transplantation, thereby potentially preventing dilative remodeling and progression to heart failure. Objective: Assessment of transport stability, long-term survival, structural organization, functional benefits, and teratoma risk of engineered heart muscle (EHM) in a chronic myocardial infarction model. Methods and Results: We constructed EHMs from human embryonic stem cell-derived cardiomyocytes and released them for transatlantic shipping following predefined quality control criteria. Two days of shipment did not lead to adverse effects on cell viability or contractile performance of EHMs (n=3, P=0.83, P=0.87). One month after ischemia/reperfusion injury, EHMs were implanted onto immunocompromised rat hearts to simulate chronic ischemia. Bioluminescence imaging showed stable engraftment with no significant cell loss between week 2 and 12 (n=6, P=0.67), preserving 25% of the transplanted cells. Despite high engraftment rates and attenuated disease progression (change in ejection fraction for EHMs, -6.71.4% versus control, -10.9 +/- 1.5%; n>12; P=0.05), we observed no difference between EHMs containing viable and nonviable human cardiomyocytes in this chronic xenotransplantation model (n>12; P=0.41). Grafted cardiomyocytes showed enhanced sarcomere alignment and increased connexin 43 expression at 220 days after transplantation. No teratomas or tumors were found in any of the animals (n=14) used for long-term monitoring. Conclusions: EHM transplantation led to high engraftment rates, long-term survival, and progressive maturation of human cardiomyocytes. However, cell engraftment was not correlated with functional improvements in this chronic myocardial infarction model. Most importantly, the safety of this approach was demonstrated by the lack of tumor or teratoma formation."],["dc.identifier.doi","10.1161/CIRCRESAHA.115.306985"],["dc.identifier.gro","3141824"],["dc.identifier.isi","000361730700010"],["dc.identifier.pmid","26291556"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1479"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/93"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien"],["dc.relation.eissn","1524-4571"],["dc.relation.issn","0009-7330"],["dc.relation.workinggroup","RG Ebert (Cardiovascular Cell Biology and Systems Medicine)"],["dc.relation.workinggroup","RG Tiburcy (Stem Cell Disease Modeling)"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","448"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Dementia and Geriatric Cognitive Disorders"],["dc.bibliographiccitation.lastpage","456"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Alexopoulos, Panagiotis"],["dc.contributor.author","Ebert, Antje"],["dc.contributor.author","Richter-Schmidinger, Tanja"],["dc.contributor.author","Schöll, E."],["dc.contributor.author","Natale, B."],["dc.contributor.author","Aguilar, C. A."],["dc.contributor.author","Gourzis, P."],["dc.contributor.author","Weih, Martin"],["dc.contributor.author","Perneczky, R."],["dc.contributor.author","Diehl-Schmid, J."],["dc.contributor.author","Kneib, Thomas"],["dc.contributor.author","Förstl, Hans"],["dc.contributor.author","Kurz, Alexander"],["dc.contributor.author","Danek, A."],["dc.contributor.author","Kornhuber, Johannes"],["dc.date.accessioned","2017-09-07T11:47:13Z"],["dc.date.available","2017-09-07T11:47:13Z"],["dc.date.issued","2010"],["dc.identifier.doi","10.1159/000312685"],["dc.identifier.gro","3149294"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/5955"],["dc.notes.intern","Kneib Crossref Import"],["dc.notes.status","public"],["dc.notes.submitter","chake"],["dc.publisher","S. Karger AG"],["dc.relation.issn","1421-9824"],["dc.title","Validation of the German Revised Addenbrooke’s Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer’s Disease and Frontotemporal Lobar Degeneration"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","FEBS Letters"],["dc.contributor.author","Xu, Hang"],["dc.contributor.author","Wali, Ruheen"],["dc.contributor.author","Cheruiyot, Cleophas"],["dc.contributor.author","Bodenschatz, Jonathan"],["dc.contributor.author","Hasenfuss, Gerd"],["dc.contributor.author","Janshoff, Andreas"],["dc.contributor.author","Habeck, Michael"],["dc.contributor.author","Ebert, Antje"],["dc.date.accessioned","2021-10-01T09:58:17Z"],["dc.date.available","2021-10-01T09:58:17Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1002/1873-3468.14189"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90029"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/534"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.eissn","1873-3468"],["dc.relation.issn","0014-5793"],["dc.relation.workinggroup","RG Hasenfuß (Transition zur Herzinsuffizienz)"],["dc.relation.workinggroup","RG Janshoff"],["dc.relation.workinggroup","RG Habeck (Bayesian Methods in Structural Biology and Biophysics)"],["dc.title","Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Circulation Research"],["dc.bibliographiccitation.volume","121"],["dc.contributor.author","Tachibana, Atsushi"],["dc.contributor.author","Santoso, Michelle R."],["dc.contributor.author","Mahmoudi, Morteza"],["dc.contributor.author","Shukla, Praveen"],["dc.contributor.author","Wang, Lei"],["dc.contributor.author","Bennett, Mihoko"],["dc.contributor.author","Goldstone, Andrew B."],["dc.contributor.author","Wang, Mouer"],["dc.contributor.author","Fukushi, Masahiro"],["dc.contributor.author","Ebert, Antje D."],["dc.contributor.author","Woo, Y. Joseph"],["dc.contributor.author","Rulifson, Eric"],["dc.contributor.author","Yang, Phillip C."],["dc.date.accessioned","2020-12-10T18:38:00Z"],["dc.date.available","2020-12-10T18:38:00Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1161/CIRCRESAHA.117.310803"],["dc.identifier.eissn","1524-4571"],["dc.identifier.issn","0009-7330"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77160"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Paracrine Effects of the Pluripotent Stem Cell-Derived Cardiac Myocytes Salvage the Injured Myocardium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]