Schmidt-Schultz, Tyede Helen

[["dc.bibliographiccitation.firstpage","15733"],["dc.bibliographiccitation.issue","38"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","15738"],["dc.bibliographiccitation.volume","108"],["dc.contributor.author","Wagner, Mayke"],["dc.contributor.author","Wu, X."],["dc.contributor.author","Tarasov, Pavel E."],["dc.contributor.author","Aisha, Ailijiang"],["dc.contributor.author","Ramsey, Christopher Bronk"],["dc.contributor.author","Schultz, Michael"],["dc.contributor.author","Schmidt-Schultz, Tyede"],["dc.contributor.author","Gresky, Julia"],["dc.date.accessioned","2018-11-07T08:51:41Z"],["dc.date.available","2018-11-07T08:51:41Z"],["dc.date.issued","2011"],["dc.description.abstract","Pastoral nomadism, as a successful economic and social system drawing on mobile herding, long-distance trade, and cavalry warfare, affected all polities of the Eurasian continent. The role that arid Inner Asia, particularly the areas of northwestern China, Kazakhstan, and Mongolia, played in the emergence of this phenomenon remains a fundamental and still challenging question in prehistoric archaeology of the Eurasian steppes. The cemetery of Liushiu (Xinjiang, China) reveals burial features, bronze bridle bits, weaponry, adornment, horse skulls, and sheep/goat bones, which, together with paleopathological changes in human skeletons, indicate the presence of mobile pastoralists and their flocks at summer pastures in the Kunlun Mountains, similar to 2,850 m above sea level. Radiocarbon dates place the onset of the burial activity between 1108 and 893 B.C. (95% probability range) or most likely between 1017 and 926 B.C. (68%). These data from the Kunlun Mountains show a wider frontier within the diversity of mobile pastoral economies of Inner Asia and support the concept of multiregional transitions toward Iron Age complex pastoralism and mounted warfare."],["dc.identifier.doi","10.1073/pnas.1105273108"],["dc.identifier.isi","000295030000021"],["dc.identifier.pmid","21911387"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21996"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.title","Radiocarbon-dated archaeological record of early first millennium BC mounted pastoralists in the Kunlun Mountains, China"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","American Journal of Physical Anthropology"],["dc.bibliographiccitation.volume","153"],["dc.contributor.author","Molnar, Erika"],["dc.contributor.author","Schultz, Michael"],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.contributor.author","Marcsik, Antonia"],["dc.contributor.author","Buczko, Krisztina"],["dc.contributor.author","Zadori, Peter"],["dc.contributor.author","Biro, Gergely"],["dc.contributor.author","Bernert, Zsolt"],["dc.contributor.author","Hajdu, Tamas"],["dc.date.accessioned","2018-11-07T09:43:17Z"],["dc.date.available","2018-11-07T09:43:17Z"],["dc.date.issued","2014"],["dc.format.extent","188"],["dc.identifier.isi","000331225100553"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34147"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.eventlocation","Calgary, CANADA"],["dc.relation.issn","1096-8644"],["dc.relation.issn","0002-9483"],["dc.title","Multidisciplinary analysis of an osteosarcoma from the 11th-12th AD centuries of Hungary"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","583"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pathology & Oncology Research"],["dc.bibliographiccitation.lastpage","587"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Molnár, Erika"],["dc.contributor.author","Schultz, Michael"],["dc.contributor.author","Schmidt-Schultz, Tyede H."],["dc.contributor.author","Marcsik, Antónia"],["dc.contributor.author","Buczkó, Krisztina"],["dc.contributor.author","Zádori, Péter"],["dc.contributor.author","Biró, Gergely"],["dc.contributor.author","Bernert, Zsolt"],["dc.contributor.author","Baumhoer, Daniel"],["dc.contributor.author","Hajdu, Tamás"],["dc.date.accessioned","2020-12-10T14:14:32Z"],["dc.date.available","2020-12-10T14:14:32Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1007/s12253-016-0153-7"],["dc.identifier.eissn","1532-2807"],["dc.identifier.issn","1219-4956"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71375"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Rare Case of an Ancient Craniofacial Osteosarcoma with Probable Surgical Intervention"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","American Journal of Physical Anthropology"],["dc.bibliographiccitation.volume","147"],["dc.contributor.author","Gresky, Julia"],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.contributor.author","Schultz, Michael"],["dc.date.accessioned","2018-11-07T09:15:35Z"],["dc.date.available","2018-11-07T09:15:35Z"],["dc.date.issued","2012"],["dc.format.extent","156"],["dc.identifier.isi","000300498700337"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27726"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.conference","81st Annual Meeting of the American-Association-of-Physical-Anthropologists"],["dc.relation.eventlocation","Portland, OR"],["dc.relation.issn","0002-9483"],["dc.title","Diseases of early first Millennium BC mounted Pastoralists in the Kunlun Mountains, China."],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4117"],["dc.bibliographiccitation.issue","6B"],["dc.bibliographiccitation.journal","Anticancer Research"],["dc.bibliographiccitation.lastpage","4119"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Schlott, Thilo"],["dc.contributor.author","Eiffert, Helmut"],["dc.contributor.author","Schmidt-Schultz, Tyede"],["dc.contributor.author","Gebhardt, Melanie"],["dc.contributor.author","Parzinger, Hermann"],["dc.contributor.author","Schultz, Michael"],["dc.date.accessioned","2018-11-07T10:54:45Z"],["dc.date.available","2018-11-07T10:54:45Z"],["dc.date.issued","2007"],["dc.description.abstract","Molecular paleopathology has become an emerging field that helps to characterize molecular markers of past disease. Especially highly sensitive genetic techniques such as PCR are an important means of unraveling changes in ancient DNA extracted from bone tissue, teeth and mummified soft tissue. In the present study, excavated bone material from the skeleton of a Scythian sovereign, morphologically and immunohistochemically suspicious of a metastatic prostate carcinoma, was analyzed by PCR for amplifiable human gene sequences. Short sequences of the human GADD153 DNA repair gene and p53 tumor suppressor gene were detectable which revealed the absence of mutations according to the data of automatic sequencing. Using bisulfite-treated DNA from the bone, methylation-specific PCR detected hypermethylated promoter sequences of the p14ARF tumor suppressor gene. In summary, these data show that it is possible: a) to amply short human DNA stretches from 2,500-year-old bone material, b) to detect tumorigenetically important genes within this DNA, c) to detect epigenetically modified DNA in ancient bone material. The finding of hypermethylated p14ARF sequences merits attention because this may indicate an intraosseal neoplastic process and may corroborate the hypothesis of prostate cancer."],["dc.identifier.isi","000251901700050"],["dc.identifier.pmid","18225581"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49636"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Int Inst Anticancer Research"],["dc.relation.issn","0250-7005"],["dc.title","Detection and analysis of cancer genes amplified from bone material of a Scythian royal burial in Arzhan near Tuva, Siberia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Paläontologische Zeitschrift"],["dc.contributor.author","Schmidt-Schultz, Tyede H."],["dc.contributor.author","Reich, Mike"],["dc.contributor.author","Schultz, Michael"],["dc.date.accessioned","2021-07-05T15:00:56Z"],["dc.date.available","2021-07-05T15:00:56Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract In an exceptional preservation state, bones conserve the entire pattern of extracellular bone matrix proteins over thousands or sometimes even millions of years. Here we present typical extracellular bone matrix proteins, which were extracted from a 3.0-million-year-old gomphothere proboscidean, and identified with special antibodies. For the first time, osteonectin, osteopontin and BMP-2 were confidently identified from the extinct Anancus arvernensis , based on late Pliocene material from Willershausen, Lower Saxony, Germany. Our study has value in demonstrating that the longevity of original extracellular bone matrix proteins is much greater than formerly expected, and that such materials may be stabilised for distinct geological periods of time, especially in Fossil Lagerstätten."],["dc.description.abstract","Abstract In an exceptional preservation state, bones conserve the entire pattern of extracellular bone matrix proteins over thousands or sometimes even millions of years. Here we present typical extracellular bone matrix proteins, which were extracted from a 3.0-million-year-old gomphothere proboscidean, and identified with special antibodies. For the first time, osteonectin, osteopontin and BMP-2 were confidently identified from the extinct Anancus arvernensis , based on late Pliocene material from Willershausen, Lower Saxony, Germany. Our study has value in demonstrating that the longevity of original extracellular bone matrix proteins is much greater than formerly expected, and that such materials may be stabilised for distinct geological periods of time, especially in Fossil Lagerstätten."],["dc.identifier.doi","10.1007/s12542-021-00566-7"],["dc.identifier.pii","566"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/87942"],["dc.language.iso","en"],["dc.notes.intern","DOI Import DOI-Import GROB-441"],["dc.relation.eissn","1867-6812"],["dc.relation.issn","0031-0220"],["dc.title","Exceptionally preserved extracellular bone matrix proteins from the late Neogene proboscidean Anancus (Mammalia: Proboscidea)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","186"],["dc.bibliographiccitation.journal","Quaternary International"],["dc.bibliographiccitation.lastpage","199"],["dc.bibliographiccitation.volume","405"],["dc.contributor.author","Gresky, Julia"],["dc.contributor.author","Wagner, Mayke"],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.contributor.author","Schwarz, Laura"],["dc.contributor.author","Wu, Xinhua"],["dc.contributor.author","Aisha, Ailijiang"],["dc.contributor.author","Tarasov, Pavel E."],["dc.contributor.author","Schultz, Michael"],["dc.date.accessioned","2020-12-10T15:20:59Z"],["dc.date.available","2020-12-10T15:20:59Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1016/j.quaint.2015.04.035"],["dc.identifier.issn","1040-6182"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72875"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","‘You must keep going’ – Musculoskeletal system stress indicators of prehistoric mobile pastoralists in Western China"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","American Journal of Physical Anthropology"],["dc.bibliographiccitation.volume","159"],["dc.contributor.author","Gresky, Julia"],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.contributor.author","Schwarz, Laura"],["dc.contributor.author","Schultz, Michael"],["dc.date.accessioned","2018-11-07T10:17:39Z"],["dc.date.available","2018-11-07T10:17:39Z"],["dc.date.issued","2016"],["dc.format.extent","161"],["dc.identifier.isi","000371255201212"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41272"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","85th Annual Meeting of the American-Association-of-Physical-Anthropologists"],["dc.relation.eventlocation","Atlanta, GA"],["dc.relation.issn","1096-8644"],["dc.relation.issn","0002-9483"],["dc.title","Fracture patterns of early first Millennium BC mounted Pastoralists in the Kunlun Mountains, China"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e65649"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Alt, Kurt W."],["dc.contributor.author","Benz, Marion"],["dc.contributor.author","Mueller, Wolfgang"],["dc.contributor.author","Berner, Margit E."],["dc.contributor.author","Schultz, Michael"],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.contributor.author","Knipper, Corina"],["dc.contributor.author","Gebel, Hans-Georg K."],["dc.contributor.author","Nissen, Hans J."],["dc.contributor.author","Vach, Werner"],["dc.date.accessioned","2018-11-07T09:23:41Z"],["dc.date.available","2018-11-07T09:23:41Z"],["dc.date.issued","2013"],["dc.description.abstract","The transition from mobile to sedentary life was one of the greatest social challenges of the human past. Yet little is known about the impact of this fundamental change on social interactions amongst early Neolithic communities, which are best recorded in the Near East. The importance of social processes associated with these economic and ecological changes has long been underestimated. However, ethnographic observations demonstrate that generalized reciprocity - such as open access to resources and land - had to be reduced to a circumscribed group before regular farming and herding could be successfully established. Our aim was thus to investigate the role of familial relationships as one possible factor within this process of segregation as recorded directly in the skeletal remains, rather than based on hypothetical correlations such as house types and social units. Here we present the revealing results of the systematically recorded epigenetic characteristics of teeth and skulls of the late Pre-Pottery Neolithic community of Basta in Southern Jordan (Figure S1). Additionally, mobility was reconstructed via a systematic strontium (Sr) isotope analysis of tooth enamel of the Basta individuals. The frequency of congenitally missing maxillary lateral incisors in the 9,000-year-old community of Basta is exceptionally high (35.7%). Genetic studies and a worldwide comparison of the general rate of this dental anomaly in modern and historic populations show that the enhanced frequency can only be explained by close familial relationships akin to endogamy. This is supported by strontium isotope analyses of teeth, indicating a local origin of almost all investigated individuals. Yet, the accompanying archaeological finds document far-reaching economic exchange with neighboring groups and a population density hitherto unparalleled. We thus conclude that endogamy in the early Neolithic village of Basta was not due to geographic isolation or a lack of exogamous mating partners but a socio-cultural choice."],["dc.identifier.doi","10.1371/journal.pone.0065649"],["dc.identifier.isi","000320755400052"],["dc.identifier.pmid","23776517"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9154"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29639"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY-NC 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/3.0"],["dc.title","Earliest Evidence for Social Endogamy in the 9,000-Year-Old-Population of Basta, Jordan"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2591"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","International Journal of Cancer"],["dc.bibliographiccitation.lastpage","2595"],["dc.bibliographiccitation.volume","121"],["dc.contributor.author","Schultz, Michael"],["dc.contributor.author","Parzinger, Hermann"],["dc.contributor.author","Posdnjakov, Dmitrij V."],["dc.contributor.author","Chikisheva, Tatjana A."],["dc.contributor.author","Schmidt-Schultz, Tyede Helen"],["dc.date.accessioned","2018-11-07T10:44:41Z"],["dc.date.available","2018-11-07T10:44:41Z"],["dc.date.issued","2007"],["dc.description.abstract","To determine whether a 2,700-year-old tumor can be reliably diagnosed using microscopic and proteomic techniques and whether such prostate carcinomas show the same morphological pattern at the micro-level as modern-day carcinomas, this case was investigated. A 40-50-year-old Scythian king who lived during the Iron Age in the steppe of Southern Siberia (Russia) suffered from macroscopically visible osteoblastic and osteoclastic lesions throughout his entire skeleton. Macro-morphological (macroscopy, encloscopy, radiology) and micro-morphological techniques (histology, scanning-electron microscopy) as well as proteomic techniques (1-D-and 2-D-electrophoresesis, Western blot) were applied. The results of the morphological and biochemical investigation proved that this mature male suffered for many years from and probably died of a carcinoma of the prostate. The diagnosis mainly rests on the results of the microscopic examination of the lesions and the positive evidence of PSA, which is an important marker for the diagnosis of prostate cancer. It is remarkable that, in this ancient case, the morphological pattern at the microlevel is the same as in recent cases. The loss of the spongy bone substance (red bone marrow) provoked chronic anemia during the final months of the life of this king. The proteomic techniques applied are new for the investigation of recent and ancient macerated bones. Sensitive and reliable biochemical markers (PSA) are an important precondition to detect such tumors in recent and ancient materials. Currently, this is the oldest known case of prostate cancer diagnosed reliably by morphological and biochemical techniques. (c) 2007 Wiley-Liss, Inc."],["dc.identifier.doi","10.1002/ijc.23073"],["dc.identifier.isi","000251109000002"],["dc.identifier.pmid","17918181"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47324"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-liss"],["dc.relation.issn","0020-7136"],["dc.title","Oldest known case of metastasizing prostate carcinoma diagnosed in the skeleton of a 2,700-year-old Scythian King from Arzhan (Siberia, Russia)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]