Now showing 1 - 3 of 3
  • 2009Journal Article
    [["dc.bibliographiccitation.firstpage","373"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","NEUROREHABILITATION AND NEURAL REPAIR"],["dc.bibliographiccitation.lastpage","381"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Rothkegel, Holger"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Rammsayer, Thomas H."],["dc.contributor.author","Trenkwalder, Claudia"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:30:31Z"],["dc.date.available","2018-11-07T08:30:31Z"],["dc.date.issued","2009"],["dc.description.abstract","Background. Focal single-session repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex has been claimed to be capable of improving motor function in Parkinson's disease. Objective. The authors sought to determine which type of rTMS protocol holds the highest potential for future therapeutic application. Methods. Twenty-two patients with Parkinson's disease received 5 different rTMS protocols on 5 consecutive days in a pseudorandomized and counterbalanced order either in the defined OFF condition or with their usual medication. The protocols tested in the present study included 2 conventional rTMS protocols (0.5 and 10 Hz) as well as the recently introduced theta burst stimulation (cTBS, iTBS) and a sham condition. Cortical excitability, motor performance (pointing movement, pronation-supination, Purdue Pegboard Test, walking), and mood were assessed before and after each session. Results. The authors observed motor training from days 1 to 4, particularly in the group on dopaminergic medication. None of the rTMS paradigms excelled placebo stimulation. The only exception was the Purdue Pegboard Test, in which all active stimulation paradigms yielded slightly stronger effects than sham stimulation. Conclusions. Within a single session, no clinically relevant difference in the rTMS protocols could be detected. Training effects outweigh and may have masked rTMS effects, particularly in the group on dopaminergic mediation."],["dc.identifier.doi","10.1177/1545968308322842"],["dc.identifier.isi","000264876100009"],["dc.identifier.pmid","18978029"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13103"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16906"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.issn","1545-9683"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Training Effects Outweigh Effects of Single-Session Conventional rTMS and Theta Burst Stimulation in PD Patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2009Journal Article
    [["dc.bibliographiccitation.artnumber","P87"],["dc.bibliographiccitation.issue","Suppl 1"],["dc.bibliographiccitation.journal","BMC Neuroscience"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Haß, Joachim"],["dc.contributor.author","Blaschke, Stefan"],["dc.contributor.author","Rammsayer, Thomas"],["dc.contributor.author","Herrmann, J. Michael"],["dc.date.accessioned","2011-04-15T06:17:14Z"],["dc.date.accessioned","2021-10-11T11:24:54Z"],["dc.date.available","2011-04-15T06:17:14Z"],["dc.date.available","2021-10-11T11:24:54Z"],["dc.date.issued","2009"],["dc.identifier.citation","Haß, Joachim; Blaschke, Stefan; Rammsayer, Thomas; Herrmann, J Michael (2009): Progress and decay – An information-theoretical view on the Janus face of time - BMC Neuroscience, Vol. 10, Nr. Suppl 1, p. P87-"],["dc.identifier.doi","10.1186/1471-2202-10-S1-P87"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6136"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90531"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.orgunit","Fakultät für Physik"],["dc.rights","Goescholar"],["dc.rights.access","openAccess"],["dc.rights.uri","http://goedoc.uni-goettingen.de/licenses"],["dc.subject","Progress and decay"],["dc.subject.ddc","530"],["dc.subject.ddc","573"],["dc.subject.ddc","573.8"],["dc.subject.ddc","612"],["dc.subject.ddc","612.8"],["dc.title","Progress and decay – An information-theoretical view on the Janus face of time"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2008Journal Article
    [["dc.bibliographiccitation.firstpage","449"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Computational Neuroscience"],["dc.bibliographiccitation.lastpage","464"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Hass, Joachim"],["dc.contributor.author","Blaschke, Stefan"],["dc.contributor.author","Rammsayer, Thomas H."],["dc.contributor.author","Herrmann, J. Michael"],["dc.date.accessioned","2018-11-07T11:08:36Z"],["dc.date.available","2018-11-07T11:08:36Z"],["dc.date.issued","2008"],["dc.description.abstract","Humans can estimate the duration of intervals of time, and psychophysical experiments show that these estimations are subject to timing errors. According to standard theories of timing, these errors increase linearly with the interval to be estimated (Weber's law), and both at longer and shorter intervals, deviations from linearity are reported. This is not easily reconciled with the accumulation of neuronal noise, which would only lead to an increase with the square root of the interval. Here, we offer a neuronal model which explains the form of the error function as a result of a constrained optimization process. The model consists of a number of synfire chains with different transmission times, which project onto a set of readout neurons. We show that an increase in the transmission time corresponds to a superlinear increase of the timing errors. Under the assumption of a fixed chain length, the experimentally observed error function emerges from optimal selection of chains for each given interval. Furthermore, we show how this optimal selection could be implemented by competitive spike-timing dependent plasticity in the connections from the chains to the readout network, and discuss implications of our model on selective temporal learning and possible neural architectures of interval timing."],["dc.identifier.doi","10.1007/s10827-008-0088-4"],["dc.identifier.isi","000259438100003"],["dc.identifier.pmid","18379866"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11166"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52822"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0929-5313"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","http://creativecommons.org/licenses/"],["dc.title","A neurocomputational model for optimal temporal processing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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