Laatsch, Hartmut G.

[["dc.bibliographiccitation.issue","13"],["dc.bibliographiccitation.journal","ChemInform"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Asolkar, Ratnakar N."],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Helmke, Elisabeth"],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2021-12-08T12:29:04Z"],["dc.date.available","2021-12-08T12:29:04Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1002/chin.200313196"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/95950"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-476"],["dc.relation.eissn","1522-2667"],["dc.relation.issn","0931-7597"],["dc.rights.uri","http://doi.wiley.com/10.1002/tdm_license_1.1"],["dc.title","Marine Bacteria. Part 16. Chalcomycin B, a New Macrolide Antibiotic from the Marine Isolate Streptomyces sp. B7064."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","893"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","898"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Asolkar, R. N."],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Helmke, Elisabeth"],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:00:23Z"],["dc.date.available","2018-11-07T10:00:23Z"],["dc.date.issued","2002"],["dc.description.abstract","In our screening of marine streptomycete isolates for bioactive components, a new macrolide antibiotic designated as chalcomycin B (1b) was isolated from the culture broth of a marine Streptomycete isolate B7064 together with chalcomycin (1a) as the active principles. The structure of the new antibiotic was determined by EI and ESI MS, H-1, C-13 and 2D NMR spectroscopy and by comparison of the NMR data with those of chalcomycin."],["dc.identifier.isi","000179023600006"],["dc.identifier.pmid","12523822"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37791"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Chalcomycin B, a new macrolide antibiotic from the marine isolate Streptomyces sp B7064"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","643"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","649"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Asolkar, R. N."],["dc.contributor.author","Kapaun, E."],["dc.contributor.author","Wagner-Dobler, I."],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:21:53Z"],["dc.date.available","2018-11-07T10:21:53Z"],["dc.date.issued","2002"],["dc.description.abstract","N-Phenylethylamides 1asimilar to1f, were isolated from cultures of three limnic strains GW90a, GW102a and GW73a. Strain GW102a delivered additionally the compound cyclo(isoleucyldehydroalanyl). (2). The structure of these compounds were assigned by a detailed spectral analysis. Due to their potential use as herbicides, various related compounds 1a, 3, 4a and 4b were synthesized. The minimum inhibitory concentration (MIC) against Chlorella vulgaris, Chlorella sorokiniana, Chlorella salina and Scenedesmus subspicatus ranged from 100 to 12.5 mug/ml. All these amides were found to be inactive against Mucor miehei, Candida albicans, and some bacteria."],["dc.identifier.isi","000177108900004"],["dc.identifier.pmid","12243454"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42181"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Phytotoxic arylethylamides from limnic bacteria using a screening with microalgae"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","530"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","534"],["dc.bibliographiccitation.volume","58"],["dc.contributor.author","Kock, Iris"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Biabani, MAF"],["dc.contributor.author","Helmke, Elisabeth"],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:25:17Z"],["dc.date.available","2018-11-07T10:25:17Z"],["dc.date.issued","2005"],["dc.description.abstract","Cultivation of the marine-derived streptomycete isolate B8005 delivered three known antibiotics, resistomycin (1), resistoflavin (3a) and tetracenomycin (4), and a further member of the rare resistomycin class, the weakly antibiotically active 1-hydroxy-1-norresistomycin (2). From a related marine strain B4842, 1 and resistoflavin methyl ether (3b) have been isolated. The formation of 2 is of interest from a biosynthetic point of view."],["dc.identifier.isi","000231787100008"],["dc.identifier.pmid","16266127"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42823"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiotics Research Assoc"],["dc.relation.issn","0021-8820"],["dc.title","1-hydroxy-1-norresistomycin and resistoflavin methyl ether: New antibiotics from marine-derived streptomycetes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","539"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","542"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Abdelfattah, M."],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Asolkar, R. N."],["dc.contributor.author","Grun-Wollny, I."],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:38:38Z"],["dc.date.available","2018-11-07T10:38:38Z"],["dc.date.issued","2003"],["dc.description.abstract","A new antibiotic, named seitomycin (1c), and the known microbial metabolite tetrangulol methyl ether (2) were found in the ethyl acetate extract of two terrestrial Streptomyces sp. isolates. The structure of the new antibiotic was elucidated by spectroscopic studies and by comparison of the NMR data with the structurally related hatomarubigin C (1a) and SM-196 B (1b). Seitomycin (1c) showed moderate antimicrobial and weak phytotoxic activity, similar to tetrangulol methyl ether (2)."],["dc.identifier.isi","000183819700005"],["dc.identifier.pmid","12931863"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45854"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Seitomycin: Isolation, structure elucidation and biological activity of a new angucycline antibiotic from a terrestrial streptomycete"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","823"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Zeitschrift für Naturforschung B"],["dc.bibliographiccitation.lastpage","829"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Pusecker, K."],["dc.contributor.author","Speitling, M."],["dc.contributor.author","Monecke, P."],["dc.contributor.author","Helmke, Elisabeth"],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:24:20Z"],["dc.date.available","2018-11-07T10:24:20Z"],["dc.date.issued","2002"],["dc.description.abstract","The marine Streptomycete isolates B5342 and B5525 forms, beside large amounts of the antitumor antibiotic chartreusin (1a), two chartreusin monoacetates as trace components. Whereas the chemical shift of the acetate methyl in le is in the normal range, the methyl group of the 2\"-acetate residue in 1b and also in the tetra- and pentaacetates shows an extreme upfield shift. The structures of the monoacetates were confirmed by extensive NMR experiments, the anisotropic shift is explained by semi-empirical calculations."],["dc.identifier.isi","000177401100016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42639"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Verlag Z Naturforsch"],["dc.relation.issn","0932-0776"],["dc.title","On marine bacteria, article 18. 2 '-chartreusin-monoacetate, a new natural product with unusual anisotropy effects from the marine isolate Streptomyces sp B5525, and its 4 '-isomer"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","686"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Zeitschrift für Naturforschung B"],["dc.bibliographiccitation.lastpage","691"],["dc.bibliographiccitation.volume","58"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Asolkar, R. N."],["dc.contributor.author","Speitling, M."],["dc.contributor.author","Hoffmann, V."],["dc.contributor.author","Grun-Wollny, I."],["dc.contributor.author","Felck, W. F."],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:38:12Z"],["dc.date.available","2018-11-07T10:38:12Z"],["dc.date.issued","2003"],["dc.description.abstract","In the course of our chemical screening of actinomycetes and other bacteria from terrestrial and marine sources, several extracts showed colourless middle polar bands with strong UV absorption at 254 nm and brown to grey colouration with anisaldehyde/sulphuric acid. Working-up of such strains led to the isolation of a number of isoflavonoids. Daidzein (1a) and genistein (1b) are very wide-spread, however, compounds like kakkatin (2b, Streptomyces sp. GW39/1530) were known only from plant sources. Additionally, three new isoflavonoids were obtained, namely 4',7-bis-(beta-cymaropyranosyl)-genistein (1e) and 4'-hydroxy-6,7-methoxyisoflavone (2c) from the actinomycete isolate HKI 129-L, and genistein-4'-(6\"-methyl)-salicylate (1d) from Streptomyces sp. isolate GW27/2506. 1d is the first natural 4'-ester of an isoflavonoid and an aromatic acid. For the first time, also two flavonoids were isolated from bacteria, apigenin (5a) and luteolin-3'-methyl ether (5b)."],["dc.identifier.isi","000185146400013"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45755"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Verlag Z Naturforsch"],["dc.relation.issn","0932-0776"],["dc.title","Flavones and new isoflavone derivatives from microorganisms: Isolation and structure elucidation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","63"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Zeitschrift für Naturforschung B"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","60"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Huth, F."],["dc.contributor.author","Grun-Wollny, B."],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T08:49:54Z"],["dc.date.available","2018-11-07T08:49:54Z"],["dc.date.issued","2005"],["dc.description.abstract","The ethyl acetate extract of the strain Streptomyces sp. GW23/1540 has yielded four new 2-alkyl-5-(hydroxymethyl)pyridine-3,4-diols, 5-hydroxymethyl-2-isopropyl-pyridine-3,4-diol (1a), 5-hydroxymethyl-2-propyl-pyridine-3,4-diol (1b), 2-sec-butyl-5-hydroxymethyl-pyridine-3,4-diol (1c), and 5-hydroxymethyl-2-isobutyl-pyridine-3,4-diol (1d). Similarly, the strain Streptomyces sp. GW63/1571 afforded 2-sec-butyl-5-hydroxymethyl-pyridine-3,4-diol (1c) and another new natural product, (3aS, 7aR)-3a-hydroxy-3a,4,7,7a-tetrahydro-1-benzofuran-2(3H)-on e (3), together with anthranilic acid, anthranilamide, and phenylacetamide. The new natural products were inactive against three micro algae, the fungus Mucor miehei, the yeast Candida albicans, and the bacteria Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Streptomyces viridochromogenes."],["dc.identifier.isi","000227483600010"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21568"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Verlag Z Naturforsch"],["dc.relation.issn","0932-0776"],["dc.title","2-alkyl-3,4-dihydroxy-5-hydroxymethylpyridine derivatives: New natural vitamin B-6 analogues from a terrestrial Streptomyces sp."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","335"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Zeitschrift für Naturforschung B"],["dc.bibliographiccitation.lastpage","337"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Mukku, VJRV"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Monecke, P."],["dc.contributor.author","Grun-Wollny, I."],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2018-11-07T10:31:46Z"],["dc.date.available","2018-11-07T10:31:46Z"],["dc.date.issued","2002"],["dc.description.abstract","From a terrestrial Streptomycete, GW 10/2517, the new 5-(2-methylphenyl)-4-pentenoic acid (1a) was isolated. The structure of la was proven by a detailed spectroscopic analysis and by synthesis."],["dc.identifier.isi","000175624200012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44190"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Verlag Z Naturforsch"],["dc.relation.issn","0932-0776"],["dc.title","5-(2-methylphenyl)-4-pentenoic acid from a terrestrial Streptomycete"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","25"],["dc.bibliographiccitation.journal","ChemInform"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Maskey, Rajendra P."],["dc.contributor.author","Helmke, Elisabeth"],["dc.contributor.author","Kayser, Oliver"],["dc.contributor.author","Fiebig, Heinz H."],["dc.contributor.author","Maier, Armin"],["dc.contributor.author","Busche, Andreas"],["dc.contributor.author","Laatsch, Hartmut"],["dc.date.accessioned","2021-12-08T12:29:22Z"],["dc.date.available","2021-12-08T12:29:22Z"],["dc.date.issued","2005"],["dc.identifier.doi","10.1002/chin.200525213"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/96051"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-476"],["dc.relation.eissn","1522-2667"],["dc.relation.issn","0931-7597"],["dc.rights.uri","http://doi.wiley.com/10.1002/tdm_license_1.1"],["dc.title","Marine Bacteria. Part 28. Anticancer and Antibacterial Trioxacarcins with High Antimalaria Activity from a Marine Streptomycete and Their Absolute Stereochemistry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]