Schwarz, Alexander

[["dc.bibliographiccitation.firstpage","1009"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren"],["dc.bibliographiccitation.lastpage","1015"],["dc.bibliographiccitation.volume","186"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Zwaka, Paul A."],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Schneider, S."],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2017-09-07T11:45:26Z"],["dc.date.available","2017-09-07T11:45:26Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: Evaluation of a new cardiac MDCT protocol using a split-bolus contrast injection protocol and single MDCT scan for reliable diagnosis of LA/LAA thrombi in comparison to TEE, optimizing radiation exposure and use of contrast agent. Materials and Methods: A total of 182 consecutive patients with drug refractory AF scheduled for PVI (62.6 % male, mean age: 64.1 +/- 10.2 years) underwent routine diagnostic work including TEE and cardiac MDCT for the evaluation of LA/LAA anatomy and thrombus formation between November 2010 and March 2012. Contrast media injection was split into a pre-bolus of 30 ml and main bolus of 70 ml iodinated contrast agent separated by a short time delay. Results: In this study, split-bolus cardiac MDCT identified 14 of 182 patients with filling defects of the LA/LAA. In all of these 14 patients, abnormalities were found in TEE. All 5 of the 14 patients with thrombus formation in cardiac MDCT were confirmed by TEE. Conclusion: MDCT was 100 % accurate for thrombus, with strong but not perfect overall results for SEC equivalent on MDCT. Key Points: Patients with no filling defect or thrombus in MDCT in the LA/LAA region are unlikely to have thrombus and may undergo PVI without TEE. Here, the role of an additional TEE in pre-procedural management prior to PVI in patients with AF has to be redefined. Using a split-bolus injection protocol increases the diagnostic accuracy of thrombus in the LA/LAA region."],["dc.identifier.doi","10.1055/s-0034-1366247"],["dc.identifier.gro","3142029"],["dc.identifier.isi","000344356700003"],["dc.identifier.pmid","24729408"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3756"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1438-9010"],["dc.relation.issn","1438-9029"],["dc.title","Split-Bolus Single-Phase Cardiac Multidetector Computed Tomography for Reliable Detection of Left Atrial Thrombus: Comparison to Transesophageal Echocardiography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1581"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","The International Journal of Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","1587"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Sohns, Jan M."],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Konietschke, Frank"],["dc.contributor.author","Placzek, Marius"],["dc.contributor.author","Weiberg, Desiree"],["dc.contributor.author","Nordlohne, Stefan"],["dc.contributor.author","Schmuck, Sebastian"],["dc.contributor.author","Schulz, Sebastian"],["dc.contributor.author","Derlin, Thorsten"],["dc.contributor.author","Staab, Wieland"],["dc.date.accessioned","2020-12-10T14:11:26Z"],["dc.date.available","2020-12-10T14:11:26Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s10554-017-1145-8"],["dc.identifier.eissn","1573-0743"],["dc.identifier.issn","1569-5794"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71072"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Incidental findings in cardiac magnetic resonance imaging: superiority of bSSFP over T1w-HASTE for extra-cardiac findings assessment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","728"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Clinical Imaging"],["dc.bibliographiccitation.lastpage","733"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Kertesz, Andras"],["dc.contributor.author","Zwaka, Paul Anton"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2018-11-07T09:23:11Z"],["dc.date.available","2018-11-07T09:23:11Z"],["dc.date.issued","2013"],["dc.description.abstract","Purpose: The purpose of the study was to determine the prevalence of fractures and incidental findings (IF) with emphasis on clinical significance. Materials and methods: A total of 784 patients were evaluated by computed tomography. Fractures and IF were registered and classified as significant if they were recommended for additional diagnostics or therapy. Results: Four hundred seventy of 784 patients (60%) sustained a fracture. Significant fractures were found in 694/1213 fractures (57%); nonsignificant fractures were found in 519/1213 (43%) fractures. A total of 972 IF were observed in 464/784 (59%) patients. Significant findings were found in 358/972 findings (37%). There were 1.5 fractures and 1.2 IF per patient. Conclusion: There is a high prevalence of significant fractures (57%) and IF (37%). (c) 2013 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.clinimag.2012.11.002"],["dc.identifier.isi","000321029100019"],["dc.identifier.pmid","23312456"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29522"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0899-7071"],["dc.title","Current perspective of multidetector computed tomography (MDCT) in patients after midface and craniofacial trauma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","35"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Clinical Imaging"],["dc.bibliographiccitation.lastpage","41"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Dabir, Darius"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Sohns, Christian"],["dc.date.accessioned","2018-11-07T09:47:13Z"],["dc.date.available","2018-11-07T09:47:13Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: Aim of this study was to investigate the incidence of relevant biliary and extrabiliary findings in patients undergoing magnetic resonance cholangiopancreatography (MRCP). Materials and Methods: Three hundred eighty-four patients underwent 1.5-Tesla MRCP, and relevant biliary and extra-biliary findings were identified. Results: Four hundred twenty-two biliary findings were identified in 384 patients (75%; 1.1 per patient). Ninety-five patients were free of any relevant biliary finding (25%). Incidental extrabiliaiy findings were observed in 763 patients (1.98/patient). Conclusion: Most of the findings can be diagnosed by MRCP, while others require further examination. Interdisciplinary involvement is recommended to optimize clinical categorization, management, and treatment of these incidental findings. (C) 2014 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.clinimag.2013.08.015"],["dc.identifier.isi","000328314100007"],["dc.identifier.pmid","24120879"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35062"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1873-4499"],["dc.relation.issn","0899-7071"],["dc.title","Current role and future potential of magnetic resonance cholangiopancreatography with an emphasis on incidental findings"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","68"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Magnetic Resonance Imaging"],["dc.bibliographiccitation.lastpage","76"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.date.accessioned","2018-11-07T09:47:14Z"],["dc.date.available","2018-11-07T09:47:14Z"],["dc.date.issued","2014"],["dc.description.abstract","PurposeTo assess the incidence of extracardiac findings in patients undergoing clinical cardiac magnetic resonance imaging (CMRI) of the heart, and to determine the influence of those findings on patient management. Materials and MethodsDuring 40 months, 854 CMRI were performed at 1.5 T. Extracardiac findings were classified as significant (group A), if recommended for additional diagnostics or therapeutic interventions, and as nonsignificant (group B). ResultsThe most frequent indication for CMRI was evaluation of cardiac stress ischemia. In all, 631 CMRI (74% of 854) showed no extracardiac pathologies. In the remaining 223 CMRI (26% of 854), a total of 286 extracardiac findings were detected. Among these findings, 49 were considered significant (group A) and 237 nonsignificant (group B). In group A, the most common findings were suspicious pulmonary nodules or masses. In group B, the most frequent findings were hepatic cysts or hemangiomas. Eight malignancies were observed with certainty at CMRI. Seven of them had been incidentally diagnosed on CMRI for the first time, and subsequently changed the patients' management. ConclusionExtracardiac findings in clinically indicated CMRI are common (about 26%). Radiologists and cardiologists should be aware of relevant extracardiac findings that might require additional diagnostics or treatment. J. Magn. Reson. Imaging 2014;39:68-76. (c) 2013 Wiley Periodicals, Inc."],["dc.identifier.doi","10.1002/jmri.24142"],["dc.identifier.isi","000328185400009"],["dc.identifier.pmid","23589475"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35065"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1522-2586"],["dc.relation.issn","1053-1807"],["dc.title","Prevalence and Clinical Relevance of Extracardiac Findings at Cardiac MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","988"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Magnetic Resonance Imaging"],["dc.bibliographiccitation.lastpage","995"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Dabir, Darius"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Dorenkamp, Marc"],["dc.contributor.author","Harrison, James L."],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Sohns, Christian"],["dc.date.accessioned","2018-11-07T09:34:47Z"],["dc.date.available","2018-11-07T09:34:47Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: To investigate the presence of relevant vascular and incidental extravascular findings in patients undergoing magnetic resonance angiography (MRA) of the thoracic aorta and origin of the great vessels. Materials and Methods: In all, 165 consecutive patients (mean age 61612 years) underwent 1.5 T MRA of the thorax. Two researchers identified vascular and incidental extravascular findings. Clinically relevant vascular findings were defined. Extravascular findings were categorized as minor (Group A, without change in patient treatment), intermediate (Group B, unclear clinical relevance, requiring additional investigations), and major (Group C, causing a change in patient treatment). Results: A total of 306 relevant vascular findings were found in our cohort. A total of 397 extravascular findings were observed among the patients and were classified as Group A findings in 81.9% (325/397 findings, observed in 146 of 165 patients), as Group B findings in 15.4% (61/397 findings, observed in 52 of 165 patients), and as Group C in 2.8% of findings (11/397). The clinically relevant Group C findings were observed in 6.7% of patients (11/165), comprising eight previously unknown neoplasms (4.8% of 165), two patients with hemodynamically relevant pericardial effusion (1.2% of 165), and one patient with spondylodiscitis (0.6% of 165) detected by MRA. Conclusion: Relevant vascular and extravascular findings were found in patients referred for thoracic MRA. Most extravascular findings can be categorized by MRA as minor, while others required further diagnostics since they may be malignant or otherwise clinically relevant. (C) 2013 Wiley Periodicals, Inc."],["dc.identifier.doi","10.1002/jmri.24442"],["dc.identifier.isi","000342342500029"],["dc.identifier.pmid","24740558"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32251"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1522-2586"],["dc.relation.issn","1053-1807"],["dc.title","Vascular and Extravascular Findings on Magnetic Resonance Angiography of the Thoracic Aorta and the Origin of the Great Vessels"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","154"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","American Heart Journal"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","165"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Schwarz, Alexander"],["dc.date.accessioned","2018-11-07T09:28:43Z"],["dc.date.available","2018-11-07T09:28:43Z"],["dc.date.issued","2013"],["dc.description.abstract","Background In coronary computed tomography (CT) angiography (CTA) prospective electrocardiography triggering requires less radiation dose than retrospective electrocardiography gating but provides less cardiac phases for interpretation. This meta-analysis presents a concise and comprehensive head-to-head comparison of image quality, diagnostic accuracy, and radiation dose of prospectively triggered coronary CTA vs retrospectively gated CTA in patients with suspected or known coronary artery disease (CAD). Methods In patients with CAD and without tachyarrhythmia, eligible studies (selected from 4 databases) compared prospectively triggered vs retrospectively gated CTA (performed with >= 64-slice CT or dual-source CT) in 2 groups having approximately similar patient characteristics, scored CTA image quality, and/or assessed how accurately CTA diagnoses >= 50% coronary stenoses compared with catheter angiography and reported the radiation dose. The data were meta-analyzed by random-effects models, with CIs provided in the text. Results Among 3,330 patients from 20 included studies, 91.3% of CTAs (segments: 97.8%) had diagnostic quality with prospective triggering and 93.3% of CTAs (segments: 98.4%) with retrospective gating (P > .05). Among 664 patients from 5 studies, the pooled sensitivity/specificity of diagnostic CTAs was 98.7%/91.3% (segment level: 91.3%/97.7%) with prospective triggering and 96.9%/95.8% (segment level: 93.1%/97.6%) with retrospective gating (P > .05). The pooled effective dose was 3.5 mSv with prospective triggering and thus, by a factor of 3.5, lower than the pooled effective dose of retrospective gating, which was 12.3 mSv (P < .01). Conclusions In patients with CAD and without tachyarrhythmia, prospectively triggered coronary CTA provides image quality and diagnostic accuracy comparable with retrospectively gated CTA, but at a much lower radiation dose. (Am Heart J 2013;165:154-163.e3.)"],["dc.identifier.doi","10.1016/j.ahj.2012.10.026"],["dc.identifier.isi","000314112300008"],["dc.identifier.pmid","23351817"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30846"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mosby-elsevier"],["dc.relation.issn","0002-8703"],["dc.title","Head-to-head comparison of prospectively triggered vs retrospectively gated coronary computed tomography angiography: Meta-analysis of diagnostic accuracy, image quality, and radiation dose"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","860"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN"],["dc.bibliographiccitation.lastpage","867"],["dc.bibliographiccitation.volume","186"],["dc.contributor.author","Sohns, J. M."],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Zwaka, Paul Anton"],["dc.contributor.author","Unterberg-Buchwald, Christine"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Schwarz, A."],["dc.date.accessioned","2018-11-07T09:36:02Z"],["dc.date.available","2018-11-07T09:36:02Z"],["dc.date.issued","2014"],["dc.description.abstract","Purpose: The aim of this study was to assess the incidence of cardiac and significant extra-cardiac findings in clinical computed tomography of the heart in patients with atrial fibrillation before pulmonary vein isolation (PVI). Materials and Methods: 224 patients (64 +/- 10 years; male 63 %) with atrial fibrillation were examined by cardiac 64-slice multidetector CT before PVI. Extra-cardiac findings were classified as \"significant\" if they were recommended to additional diagnostics or therapy, and otherwise as \"non-significant\". Additionally, cardiac findings were documented in detail. Results: A total of 724 cardiac findings were identified in 203 patients (91 % of patients). Additionally, a total of 619 extra-cardiac findings were identified in 179 patients (80 % of patients). Among these extra-cardiac findings 196 (32 %) were \"significant\", and 423 (68 %) were \"non-significant\". In 2 patients (1 %) a previously unknown malignancy was detected (esophageal cancer and lung cancer, local stage, no metastasis). 203 additional imaging diagnostics followed to clarify the \"significant\" findings (124 additional CT, costs 38 314.69 US dollars). Overall, there were 3.2 cardiac and 2.8 extra-cardiac findings per patient. Extra-cardiac findings appear significantly more frequently in patients over 60 years old, in smokers and in patients with a history of cardiac findings (p < 0.05). Conclusion: Cardiac CT scans before PVI should be screened for extracardiac incidental findings that could have important clinical implications for each patient. Key points: Cardiac and extra-cardiac findings are common in patients with an indication for pulmonary vein isolation on previous CT scans. Malignancies can be detected in 1 % of all patients. 32 % of all extra-cardiac findings can be of significant relevance with consequences for patients. Altogether, there are 3.2 cardiac and 2.8 extra-cardiac findings in patients with indication for pulmonary vein isolation and CT. Extra-cardiac findings appear significantly more frequently in patients over 60 years old, in smokers and in patients with a history of cardiac findings (p < 0.05). Citation Format:. Sohns JM, Menke J, Staab W et al. Current Role of Cardiac and Extra-Cardiac Pathologies in Clinically Indicated Cardiac Computed Tomographywith Emphasis on Status Before Pulmonary Vein Isolation."],["dc.identifier.doi","10.1055/s-0034-1366107"],["dc.identifier.isi","000340832100003"],["dc.identifier.pmid","24648234"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32523"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","1438-9010"],["dc.relation.issn","1438-9029"],["dc.title","Current Role of Cardiac and Extra-Cardiac Pathologies in Clinically Indicated Cardiac Computed Tomography with Emphasis on Status Before Pulmonary Vein Isolation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]