Schwarz, Alexander

[["dc.bibliographiccitation.artnumber","e52218"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Bader, Oliver"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Kraneveld, Eefje A."],["dc.contributor.author","Tangwattanchuleeporn, Marut"],["dc.contributor.author","Schmidt, Pia"],["dc.contributor.author","Jacobsen, Mette D."],["dc.contributor.author","Gross, Uwe"],["dc.contributor.author","de Groot, Piet W. J."],["dc.contributor.author","Weig, Michael S."],["dc.date.accessioned","2018-11-07T09:02:13Z"],["dc.date.available","2018-11-07T09:02:13Z"],["dc.date.issued","2012"],["dc.description.abstract","Genomic plasticity is a mechanism for adaptation to environmental cues such as host responses and antifungal drug pressure in many fungi including the human pathogenic yeast Candida glabrata. In this study we evaluated the phenotypic and genotypic stability of the world-wide used C. glabrata reference strain CBS138/ ATCC2001 under laboratory conditions. A set of ten lineages of this wild type strain and genetically modified progenies were obtained from different scientific laboratories, and analyzed for genotypic and phenotypic alterations. Even though the derivates were indistinguishable by multi locus sequence typing, different phenotypic groups that correlated with specific karyotypic changes were observed. In addition, modifications in the adherence capacity to plastic surface emerged that were shown to correlate with quantitative changes in adhesin gene expression rather than subtelomeric gene loss or differences in the number of macrosatellite repeats within adhesin genes. These results confirm the genomic plasticity of C. glabrata and show that chromosomal aberrations and functional adaptations may occur not only during infection and under antimicrobial therapy, but also under laboratory conditions without extreme selective pressures. These alterations can significantly affect phenotypic properties such as cell surface attributes including adhesion and the cell wall carbohydrate composition and therefore, if unnoticed, may adulterate the outcome of genetic studies."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.1371/journal.pone.0052218"],["dc.identifier.isi","000312794500117"],["dc.identifier.pmid","23284942"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8472"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24630"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Gross Karyotypic and Phenotypic Alterations among Different Progenies of the Candida glabrata CBS138/ATCC2001 Reference Strain"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","346"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Open Medicine"],["dc.bibliographiccitation.lastpage","353"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Büttner, Benedikt"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Mewes, Caspar"],["dc.contributor.author","Kristof, Katalin"],["dc.contributor.author","Hinz, José"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Mansur, Ashham"],["dc.contributor.author","Bergmann, Ingo"],["dc.date.accessioned","2019-07-09T11:51:16Z"],["dc.date.available","2019-07-09T11:51:16Z"],["dc.date.issued","2019"],["dc.description.abstract","Intraneural injection of a local anesthetic can damage the nerve, yet it occurs frequently during distal sciatic block with no neurological sequelae. This has led to a controversy about the optimal needle tip placement that results from the particular anatomy of the sciatic nerve with its paraneural sheath. The study population included patients undergoing lower extremity surgery under popliteal sciatic nerve block. Ultrasound-guidance was used to position the needle tip subparaneurally and to monitor the injection of the local anesthetic. Sonography and magnetic resonance imaging were used to assess the extent of the subparaneural injection. Twenty-two patients participated. The median sciatic cross-sectional area increased from 57.8 mm2 pre-block to 110.8 mm2 immediately post-block. An intraneural injection according to the current definition was seen in 21 patients. Two patients had sonographic evidence of an intrafascicular injection, which was confirmed by MRI in one patient (the other patient refused further examinations). No patient reported any neurological symptoms. A subparaneural injection in the popliteal segment of the distal sciatic nerve is actually rarely intraneural, i.e. intrafascicular. This may explain the discrepancy between the conventional sonographic evidence of an intraneural injection and the lack of neurological sequelae."],["dc.identifier.doi","10.1515/med-2019-0034"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16091"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59913"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","610"],["dc.title","Subparaneural injection in popliteal sciatic nerve blocks evaluated by MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","3"],["dc.bibliographiccitation.journal","BMC Urology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Behnes, Carl Ludwig"],["dc.contributor.author","Schlegel, Christina"],["dc.contributor.author","Shoukier, Moneef"],["dc.contributor.author","Magiera, Isabella"],["dc.contributor.author","Henschke, Frank"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Loertzer, Hagen"],["dc.date.accessioned","2018-11-07T09:29:10Z"],["dc.date.available","2018-11-07T09:29:10Z"],["dc.date.issued","2013"],["dc.description.abstract","Background: Papillary renal cell carcinoma is a rare cancer. Some cases can be attributed to individuals with hereditary renal cell carcinomas usually consisting of the clear cell subtype. In addition, two syndromes with hereditary papillary renal cell carcinoma have been described. One is the hereditary leiomyomatosis and renal cell carcinoma, which is characterized by cutaneous and uterine leiomyomas and renal cell carcinoma mostly consisting of the papillary renal cell carcinoma type II with a worse prognosis. Case presentation: We describe a case of a 30-year-old woman with hereditary leiomyomatosis and renal cell carcinoma syndrome with extensively metastasized papillary renal cell carcinoma, primarily diagnosed in a cervical lymph node lacking leiomyomas at any site. Conclusion: Papillary renal cell carcinoma in young patients should be further investigated for a hereditary variant like the hereditary leiomyomatosis and renal cell carcinoma even if leiomyomas could not be detected. A detailed histological examination and search for mutations is essential for the survival of patients and relatives."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2013"],["dc.identifier.doi","10.1186/1471-2490-13-3"],["dc.identifier.isi","000314924400001"],["dc.identifier.pmid","23320739"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30953"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2490"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Hereditary papillary renal cell carcinoma primarily diagnosed in a cervical lymph node: a case report of a 30-year-old woman with multiple metastases"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","110"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Parasitology"],["dc.bibliographiccitation.lastpage","119"],["dc.bibliographiccitation.volume","139"],["dc.contributor.author","Das, Guerbuez"],["dc.contributor.author","Abel, Hansjoerg"],["dc.contributor.author","Humburg, Julia"],["dc.contributor.author","Schwarz, A."],["dc.contributor.author","Rautenschlein, Silke"],["dc.contributor.author","Breves, Gerhard"],["dc.contributor.author","Gauly, Matthias"],["dc.date.accessioned","2018-11-07T09:15:47Z"],["dc.date.available","2018-11-07T09:15:47Z"],["dc.date.issued","2012"],["dc.description.abstract","This study examined whether Ascaridia galli infection can be controlled by dietary non-starch polysaccharides (NSP) in chickens. One-day-old chicks were fed either a basal diet (CON) or CON plus insoluble NSP (I-NSP), or CON plus soluble NSP (S-NSP) for 11 weeks. Three weeks later, birds from half of each feeding group were inoculated with 250 embryonated eggs of A. galli, and slaughtered 8 weeks post-infection to determine worm counts. Both NSP diets, particularly S-NSP, increased prevalence of infection (P<0.05) and worm burden (roughly +50%) of the birds (P<0.001). A. galli infection caused a less efficient (P = 0.013) feed utilization for body weight gain (BWG) resulting in lower body weights (P<0.001) irrespective of type of diet consumed. NSP-fed birds, particularly those on I-NSP, consumed more (+ 8%) feed per unit BWG and showed retarded (P<0.001) BW development compared to CON-fed birds. Intracaecal pH was lowered by S-NSP (P<0.05). Both NSP diets increased the volatile fatty acids pool size in caeca (P<0.001) with S-NSP exerting a greater effect (+ 46%) than I-NSF (+ 24%). It is concluded that both NSPs supplemented diets alter gastrointestinal environment in favour of the nematode establishment, and thus have no potential for controlling A. galli infection in chickens."],["dc.identifier.doi","10.1017/S0031182011001636"],["dc.identifier.isi","000299580900012"],["dc.identifier.pmid","21939584"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8762"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27779"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cambridge Univ Press"],["dc.relation.issn","0031-1820"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","The effects of dietary non-starch polysaccharides on Ascaridia galli infection in grower layers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1066"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","JURA - Juristische Ausbildung"],["dc.bibliographiccitation.lastpage","1076"],["dc.bibliographiccitation.volume","36"],["dc.contributor.affiliation","Schwarz, Alexander;"],["dc.contributor.author","Schwarz, Alexander"],["dc.date.accessioned","2022-11-28T10:29:35Z"],["dc.date.available","2022-11-28T10:29:35Z"],["dc.date.issued","2014-11-09"],["dc.date.updated","2022-11-27T10:13:34Z"],["dc.identifier.doi","10.1515/jura-2014-0123"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/117464"],["dc.language.iso","de"],["dc.notes.intern","DeepGreen Import"],["dc.publisher","De Gruyter"],["dc.relation.eissn","1612-7021"],["dc.relation.issn","0170-1452"],["dc.title","Die Fallstricke des Diplomatenrechts"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e12958"],["dc.bibliographiccitation.issue","43"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","97"],["dc.contributor.author","Büttner, Benedikt"],["dc.contributor.author","Dracklé, Joschka"],["dc.contributor.author","Kristof, Katalin"],["dc.contributor.author","Hinz, José"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Mansur, Ashham"],["dc.contributor.author","Bergmann, Ingo"],["dc.date.accessioned","2020-12-10T18:20:05Z"],["dc.date.available","2020-12-10T18:20:05Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1097/MD.0000000000012958"],["dc.identifier.issn","0025-7974"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15719"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75456"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Paths of femoral nerve catheters placed using ultrasound-guided in plane vs out of plane techniques"],["dc.title.alternative","A randomized controlled clinical trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]