Potapov, Anatolij P.

[["dc.bibliographiccitation.firstpage","97"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","100"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Krull, Mathias"],["dc.contributor.author","Voss, Nico"],["dc.contributor.author","Choi, Claudia"],["dc.contributor.author","Pistor, Susanne"],["dc.contributor.author","Potapov, Anatolij"],["dc.contributor.author","Wingender, Edgar"],["dc.date.accessioned","2019-07-10T08:12:52Z"],["dc.date.available","2019-07-10T08:12:52Z"],["dc.date.issued","2003"],["dc.description.abstract","TRANSPATH® is a database system about gene regulatory networks that combines encyclopedic information on signal transduction with tools for visualization and analysis. The integration with TRANSFAC®, a database about transcription factors and their DNA binding sites, provides the possibility to obtain complete signaling pathways from ligand to target genes and their products, which may themselves be involved in regulatory action. As of July 2002, the TRANSPATH Professional release 3.2 contains about 9800 molecules, >1800 genes and >11 400 reactions collected from ~5000 references. With the ArrayAnalyzerTM, an integrated tool has been developed for evaluation of microarray data. It uses the TRANSPATH data set to identify key regulators in pathways connected with up- or down-regulated genes of the respective array. The key molecules and their surrounding networks can be viewed with the PathwayBuilderTM, a tool that offers four different modes of visualization. More information on TRANSPATH is available at http://www.biobase.de/pages/products/databases.html."],["dc.identifier.fs","12173"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4112"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61065"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1362-4962"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","TRANSPATH (R): an integrated database on signal transduction and a tool for array analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","D546"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","D551"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Krull, Mathias"],["dc.contributor.author","Pistor, Susanne"],["dc.contributor.author","Voss, Nico"],["dc.contributor.author","Kel, Alexander E."],["dc.contributor.author","Reuter, Ingmar"],["dc.contributor.author","Kronenberg, Deborah"],["dc.contributor.author","Michael, Holger"],["dc.contributor.author","Schwarzer, Knut"],["dc.contributor.author","Potapov, Anatolij P."],["dc.contributor.author","Choi, Claudia"],["dc.contributor.author","Kel-Margoulis, Olga"],["dc.contributor.author","Wingender, Edgar"],["dc.date.accessioned","2018-11-07T10:39:39Z"],["dc.date.available","2018-11-07T10:39:39Z"],["dc.date.issued","2006"],["dc.description.abstract","TRANSPATH (R) is a database about signal transduction events. It provides information about signaling molecules, their reactions and the pathways these reactions constitute. The representation of signaling molecules is organized in a number of orthogonal hierarchies reflecting the classification of the molecules, their species-specific or generic features, and their post-translational modifications. Reactions are similarly hierarchically organized in a three-layer architecture, differentiating between reactions that are evidenced by individual publications, generalizations of these reactions to construct species-independent 'reference pathways' and the 'semantic projections' of these pathways. A number of search and browse options allow easy access to the database contents, which can be visualized with the tool PathwayBuilder (TM). The module PathoSign adds data about pathologically relevant mutations in signaling components, including their genotypes and phenotypes. TRANSPATH (R) and PathoSign can be used as encyclopaedia, in the educational process, for vizualization and modeling of signal transduction networks and for the analysis of gene expression data. TRANSPATH (R) Public 6.0 is freely accessible for users from non-profit organizations under http://www.gene-regulation.com/pub/databases.html."],["dc.identifier.doi","10.1093/nar/gkj107"],["dc.identifier.isi","000239307700118"],["dc.identifier.pmid","16381929"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46101"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1362-4962"],["dc.relation.issn","0305-1048"],["dc.title","TRANSPATH (R): an information resource for storing and visualizing signaling pathways and their pathological aberrations"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]