Potapov, Anatolij P.

[["dc.bibliographiccitation.firstpage","D540"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","D545"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Potapov, Anatolij P."],["dc.contributor.author","Liebich, Ines"],["dc.contributor.author","Doenitz, Juergen"],["dc.contributor.author","Schwarzer, Knut"],["dc.contributor.author","Sasse, Nicole"],["dc.contributor.author","Schoeps, Torsten"],["dc.contributor.author","Crass, Torsten"],["dc.contributor.author","Wingender, Edgar"],["dc.date.accessioned","2018-11-07T10:39:42Z"],["dc.date.available","2018-11-07T10:39:42Z"],["dc.date.issued","2006"],["dc.description.abstract","EndoNet is a new database that provides information about the components of endocrine networks and their relations. It focuses on the endocrine cell-to-cell communication and enables the analysis of intercellular regulatory pathways in humans. In the EndoNet data model, two classes of components span a bipartite directed graph. One class represents the hormones ( in the broadest sense) secreted by defined donor cells. The other class consists of the acceptor or target cells expressing the corresponding hormone receptors. The identity and anatomical environment of cell types, tissues and organs is defined through references to the CYTOMER (R) ontology. With the EndoNet user interface, it is possible to query the database for hormones, receptors or tissues and to combine several items from different search rounds in one complex result set, from which a network can be reconstructed and visualized. For each entity, a detailed characteristics page is available. Some well-established endocrine pathways are offered as showcases in the form of predefined result sets. These sets can be used as a starting point for a more complex query or for obtaining a quick overview. The EndoNet database is accessible at http://endonet.bioinf.med.uni-goettingen.de/."],["dc.identifier.doi","10.1093/nar/gkj121"],["dc.identifier.isi","000239307700117"],["dc.identifier.pmid","16381928"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46112"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1362-4962"],["dc.relation.issn","0305-1048"],["dc.title","EndoNet: an information resource about endocrine networks"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","D546"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","D551"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Krull, Mathias"],["dc.contributor.author","Pistor, Susanne"],["dc.contributor.author","Voss, Nico"],["dc.contributor.author","Kel, Alexander E."],["dc.contributor.author","Reuter, Ingmar"],["dc.contributor.author","Kronenberg, Deborah"],["dc.contributor.author","Michael, Holger"],["dc.contributor.author","Schwarzer, Knut"],["dc.contributor.author","Potapov, Anatolij P."],["dc.contributor.author","Choi, Claudia"],["dc.contributor.author","Kel-Margoulis, Olga"],["dc.contributor.author","Wingender, Edgar"],["dc.date.accessioned","2018-11-07T10:39:39Z"],["dc.date.available","2018-11-07T10:39:39Z"],["dc.date.issued","2006"],["dc.description.abstract","TRANSPATH (R) is a database about signal transduction events. It provides information about signaling molecules, their reactions and the pathways these reactions constitute. The representation of signaling molecules is organized in a number of orthogonal hierarchies reflecting the classification of the molecules, their species-specific or generic features, and their post-translational modifications. Reactions are similarly hierarchically organized in a three-layer architecture, differentiating between reactions that are evidenced by individual publications, generalizations of these reactions to construct species-independent 'reference pathways' and the 'semantic projections' of these pathways. A number of search and browse options allow easy access to the database contents, which can be visualized with the tool PathwayBuilder (TM). The module PathoSign adds data about pathologically relevant mutations in signaling components, including their genotypes and phenotypes. TRANSPATH (R) and PathoSign can be used as encyclopaedia, in the educational process, for vizualization and modeling of signal transduction networks and for the analysis of gene expression data. TRANSPATH (R) Public 6.0 is freely accessible for users from non-profit organizations under http://www.gene-regulation.com/pub/databases.html."],["dc.identifier.doi","10.1093/nar/gkj107"],["dc.identifier.isi","000239307700118"],["dc.identifier.pmid","16381929"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46101"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1362-4962"],["dc.relation.issn","0305-1048"],["dc.title","TRANSPATH (R): an information resource for storing and visualizing signaling pathways and their pathological aberrations"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]