Luther, Stefan

[["dc.bibliographiccitation.firstpage","105275"],["dc.bibliographiccitation.journal","Communications in Nonlinear Science and Numerical Simulation"],["dc.bibliographiccitation.volume","86"],["dc.contributor.author","Barrio, Roberto"],["dc.contributor.author","Coombes, Stephen"],["dc.contributor.author","Desroches, Mathieu"],["dc.contributor.author","Fenton, Flavio"],["dc.contributor.author","Luther, Stefan"],["dc.contributor.author","Pueyo, Esther"],["dc.date.accessioned","2020-12-10T14:23:10Z"],["dc.date.available","2020-12-10T14:23:10Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.cnsns.2020.105275"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71861"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/351"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C03: Erholung nach Herzinsuffizienz: Analyse der transmuralen mechano-elektrischen Funktionsstörung"],["dc.relation.workinggroup","RG Luther (Biomedical Physics)"],["dc.title","Excitable dynamics in neural and cardiac systems"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","overview_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","P2835"],["dc.bibliographiccitation.firstpage","591"],["dc.bibliographiccitation.issue","suppl_1"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Quinonez Uribe, R. A."],["dc.contributor.author","Luther, S."],["dc.contributor.author","Richter, C."],["dc.date.accessioned","2019-02-26T14:39:41Z"],["dc.date.available","2019-02-26T14:39:41Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1093/eurheartj/ehy565.P2835"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57621"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/273"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C03: Erholung nach Herzinsuffizienz: Analyse der transmuralen mechano-elektrischen Funktionsstörung"],["dc.relation.issn","0195-668X"],["dc.relation.workinggroup","RG Luther (Biomedical Physics)"],["dc.title","Low-energy control of spatiotemporal cardiac dynamics using structured photo-stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

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[["dc.contributor.author","Hornung, D."],["dc.contributor.author","Biktashev, V. N."],["dc.contributor.author","Otani, N. F."],["dc.contributor.author","Shajahan, T. K."],["dc.contributor.author","Baig, T."],["dc.contributor.author","Berg, S."],["dc.contributor.author","Han, S."],["dc.contributor.author","Krinsky, V. I."],["dc.contributor.author","Luther, Stefan"],["dc.date.accessioned","2022-05-13T09:17:31Z"],["dc.date.available","2022-05-13T09:17:31Z"],["dc.date.issued","2017-02-28"],["dc.identifier.doi","10.6084/m9.figshare.c.3704707"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107859"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/220"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C03: Erholung nach Herzinsuffizienz: Analyse der transmuralen mechano-elektrischen Funktionsstörung"],["dc.relation.workinggroup","RG Luther (Biomedical Physics)"],["dc.title","Supplementary material from \"Mechanisms of vortices termination in the cardiac muscle\""],["dc.type","research_data"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Physiology"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Gizzi, Alessio"],["dc.contributor.author","Cherry, Elizabeth M."],["dc.contributor.author","Gilmour, Robert F."],["dc.contributor.author","Luther, Stefan"],["dc.contributor.author","Filippi, Simonetta"],["dc.contributor.author","Fenton, Flavio H."],["dc.date.accessioned","2022-03-01T11:44:24Z"],["dc.date.available","2022-03-01T11:44:24Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.3389/fphys.2013.00071"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/103015"],["dc.notes.intern","DOI-Import GROB-531"],["dc.relation.eissn","1664-042X"],["dc.title","Effects of Pacing Site and Stimulation History on Alternans Dynamics and the Development of Complex Spatiotemporal Patterns in Cardiac Tissue"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","230"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Macromolecular Materials and Engineering"],["dc.bibliographiccitation.lastpage","237"],["dc.bibliographiccitation.volume","296"],["dc.contributor.author","van den Berg, Thomas H."],["dc.contributor.author","Wormgoor, Willem D."],["dc.contributor.author","Luther, Stefan"],["dc.contributor.author","Lohse, Detlef"],["dc.date.accessioned","2022-03-01T11:46:22Z"],["dc.date.available","2022-03-01T11:46:22Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1002/mame.201000339"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/103648"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-531"],["dc.relation.issn","1438-7492"],["dc.title","Phase-Sensitive Constant Temperature Anemometry"],["dc.title.alternative","Phase-Sensitive Constant Temperature Anemometry"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","157"],["dc.bibliographiccitation.lastpage","158"],["dc.contributor.author","Schlemmer, Alexander"],["dc.contributor.author","Zwirnmann, Henning"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Parlitz, Ulrich"],["dc.contributor.author","Luther, Stefan"],["dc.date.accessioned","2019-02-26T15:08:20Z"],["dc.date.available","2019-02-26T15:08:20Z"],["dc.date.issued","2014"],["dc.description.abstract","We evaluate several machine learning algorithms in the context of long-term prediction of cardiac diseases. Results from applying K Nearest Neighbors Classifiers (KNN), Support Vector Machines (SVM) and Random Forests (RF) to data from a cardiological long-term study suggests that multivariate methods can significantly improve classification results. SVMs were found to yield the best results in Matthews Correlation Coefficient and are most stable with respect to a varying number of features."],["dc.identifier.doi","10.1109/ESGCO.2014.6847567"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57623"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/53"],["dc.language.iso","en"],["dc.notes.status","fcwi"],["dc.publisher","IEEE"],["dc.publisher.place","Piscataway, NJ"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C03: Erholung nach Herzinsuffizienz: Analyse der transmuralen mechano-elektrischen Funktionsstörung"],["dc.relation.conference","8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)"],["dc.relation.eventend","2014-05-28"],["dc.relation.eventlocation","Trento, Italy"],["dc.relation.eventstart","2014-05-25"],["dc.relation.isbn","978-1-4799-3969-5"],["dc.relation.isbn","978-1-4799-3968-8"],["dc.relation.isbn","978-1-4799-3970-1"],["dc.relation.ispartof","2014 8th Conference of the European Study Group on Cardiovascoular Oscillations (ESGCO 2014)"],["dc.relation.workinggroup","RG Luther (Biomedical Physics)"],["dc.title","Evaluation of Machine Learning Methods for the Long-Term Prediction of Cardiac Diseases"],["dc.type","conference_paper"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","279"],["dc.bibliographiccitation.lastpage","294"],["dc.bibliographiccitation.seriesnr","20"],["dc.contributor.author","Krinsky, Valentin I."],["dc.contributor.author","Biktashev, Vadim N."],["dc.contributor.author","Otani, Niels F."],["dc.contributor.author","Luther, Stefan"],["dc.contributor.editor","Aranson, Igor S."],["dc.contributor.editor","Pikovsky, Arkady"],["dc.contributor.editor","Rulkov, Nikolai F."],["dc.contributor.editor","Tsimring, Lev S."],["dc.date.accessioned","2019-02-05T14:12:54Z"],["dc.date.available","2019-02-05T14:12:54Z"],["dc.date.issued","2017"],["dc.description.abstract","Methods for termination of three-dimensional electrical vortices in the heart are needed for development of patient-friendly cardiac defibrillation techniques (Nature 475, 235, 2011). The defibrillation technique used today is the delivery of a high-energy electric shock (360 J, 1 kV, 30 A, 12 ms, when applied externally) often associated with severe side effects. Developing low-energy defibrillation methods are hampered by two problems: the unknown locations of the cores of the vortices, and the unpredictable phases of the vortex waves rotating around these cores. The first problem has been resolved through the use of electric field pulses to excite the cores of all pinned vortices simultaneously. Approaches to solve the second problem are being developed. One of them is based on the phase scanning of all pinned vortices in parallel to hit the critical time window (“Vulnerable Window”, VW) of every pinned vortex. We investigate the related physical mechanisms and describe problems created by scanning. We describe also a mechanism by which a 3-dim scroll vortex may be terminated with a VW of the full 2π radians. It makes knowledge of the wave phase no longer required. We describe a mechanism terminating also a free (not pinned) vortex, when the vortex’s core passes not very far from a defect. About 500 experiments with termination of vortices during ventricular fibrillation in pig isolated hearts confirm that pinned vortices, hidden from direct observation, are significant in fibrillation. These results form a physical basis needed for creation of new effective methods for termination vortices underlying fibrillation."],["dc.identifier.doi","10.1007/978-3-319-53673-6_17"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57522"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/166"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.publisher","Springer"],["dc.publisher.place","Cham, Switzerland"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | A02: Bedeutung des Phosphatase-Inhibitors-1 für die SR-spezifische Modulation der Beta- adrenozeptor-Signalkaskade"],["dc.relation","SFB 1002 | A03: Bedeutung CaMKII-abhängiger Mechanismen für die Arrhythmogenese bei Herzinsuffizienz"],["dc.relation.crisseries","Nonlinear Systems and Complexity"],["dc.relation.doi","10.1007/978-3-319-53673-6"],["dc.relation.isbn","978-3-319-53672-9"],["dc.relation.isbn","978-3-319-53673-6"],["dc.relation.ispartof","Advances in Dynamics, Patterns, Cognition. Challenges in Complexity"],["dc.relation.ispartofseries","Nonlinear Systems and Complexity; 20"],["dc.relation.issn","2195-9994"],["dc.relation.issn","2196-0003"],["dc.relation.workinggroup","RG Luther (Biomedical Physics)"],["dc.title","Vortices Termination in the Cardiac Muscle"],["dc.type","book_chapter"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2221"],["dc.bibliographiccitation.issue","1918"],["dc.bibliographiccitation.journal","Philosophical Transactions of the Royal Society of London. A, Mathematical, Physical and Engineering Sciences"],["dc.bibliographiccitation.lastpage","2236"],["dc.bibliographiccitation.volume","368"],["dc.contributor.author","Bittihn, Philip"],["dc.contributor.author","Squires, Amgad"],["dc.contributor.author","Luther, Gisa"],["dc.contributor.author","Bodenschatz, Eberhard"],["dc.contributor.author","Krinsky, Valentin"],["dc.contributor.author","Parlitz, Ulrich"],["dc.contributor.author","Luther, Stefan"],["dc.date.accessioned","2018-11-07T08:43:15Z"],["dc.date.available","2018-11-07T08:43:15Z"],["dc.date.issued","2010"],["dc.description.abstract","Life-threatening cardiac arrhythmias are associated with the existence of stable and unstable spiral waves. Termination of such complex spatio-temporal patterns by local control is substantially limited by anchoring of spiral waves at natural heterogeneities. Far-field pacing (FFP) is a new local control strategy that has been shown to be capable of unpinning waves from obstacles. In this article, we investigate in detail the FFP unpinning mechanism for a single rotating wave pinned to a heterogeneity. We identify qualitatively different phase regimes of the rotating wave showing that the concept of vulnerability is important but not sufficient to explain the failure of unpinning in all cases. Specifically, we find that a reduced excitation threshold can lead to the failure of unpinning, even inside the vulnerable window. The critical value of the excitation threshold (below which no unpinning is possible) decreases for higher electric field strengths and larger obstacles. In contrast, for a high excitation threshold, the success of unpinning is determined solely by vulnerability, allowing for a convenient estimation of the unpinning success rate. In some cases, we also observe phase resetting in discontinuous phase intervals of the spiral wave. This effect is important for the application of multiple stimuli in experiments."],["dc.identifier.doi","10.1098/rsta.2010.0038"],["dc.identifier.isi","000276266400007"],["dc.identifier.pmid","20368243"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19914"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Royal Soc"],["dc.relation.issn","1364-503X"],["dc.title","Phase-resolved analysis of the susceptibility of pinned spiral waves to far-field pacing in a two-dimensional model of excitable media"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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