Pöhlmann, Stefan

[["dc.bibliographiccitation.firstpage","5210"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Nucleic Acids Research"],["dc.bibliographiccitation.lastpage","5222"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Korniy, Natalia"],["dc.contributor.author","Goyal, Akanksha"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Samatova, Ekaterina"],["dc.contributor.author","Peske, Frank"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Rodnina, Marina V"],["dc.date.accessioned","2020-12-10T18:19:35Z"],["dc.date.available","2020-12-10T18:19:35Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1093/nar/gkz202"],["dc.identifier.eissn","1362-4962"],["dc.identifier.issn","0305-1048"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16451"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75304"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0152134"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PloS one"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Krüger, Nadine"],["dc.contributor.author","Zmora, Pawel"],["dc.contributor.author","Wrensch, Florian"],["dc.contributor.author","Herrler, Georg"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2019-07-09T11:42:14Z"],["dc.date.available","2019-07-09T11:42:14Z"],["dc.date.issued","2016"],["dc.description.abstract","New World bats have recently been discovered to harbor influenza A virus (FLUAV)-related viruses, termed bat-associated influenza A-like viruses (batFLUAV). The internal proteins of batFLUAV are functional in mammalian cells. In contrast, no biological functionality could be demonstrated for the surface proteins, hemagglutinin (HA)-like (HAL) and neuraminidase (NA)-like (NAL), and these proteins need to be replaced by their human counterparts to allow spread of batFLUAV in human cells. Here, we employed rhabdoviral vectors to study the role of HAL and NAL in viral entry. Vectors pseudotyped with batFLUAV-HAL and -NAL were able to enter bat cells but not cells from other mammalian species. Host cell entry was mediated by HAL and was dependent on prior proteolytic activation of HAL and endosomal low pH. In contrast, sialic acids were dispensable for HAL-driven entry. Finally, the type II transmembrane serine protease TMPRSS2 was able to activate HAL for cell entry indicating that batFLUAV can utilize human proteases for HAL activation. Collectively, these results identify viral and cellular factors governing host cell entry driven by batFLUAV surface proteins. They suggest that the absence of a functional receptor precludes entry of batFLUAV into human cells while other prerequisites for entry, HAL activation and protonation, are met in target cells of human origin."],["dc.identifier.doi","10.1371/journal.pone.0152134"],["dc.identifier.pmid","27028521"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13149"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/58625"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S840"],["dc.bibliographiccitation.issue","suppl_3"],["dc.bibliographiccitation.journal","The Journal of Infectious Diseases"],["dc.bibliographiccitation.lastpage","S849"],["dc.bibliographiccitation.volume","204"],["dc.contributor.author","Kühl, Annika"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Müller, Marcel A."],["dc.contributor.author","Munster, Vincent J."],["dc.contributor.author","Gnirß, Kerstin"],["dc.contributor.author","Kiene, Miriam"],["dc.contributor.author","Tsegaye, Theodros Solomon"],["dc.contributor.author","Behrens, Georg"],["dc.contributor.author","Herrler, Georg"],["dc.contributor.author","Feldmann, Heinz"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2022-10-06T13:34:58Z"],["dc.date.available","2022-10-06T13:34:58Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1093/infdis/jir306"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116022"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1537-6613"],["dc.relation.issn","0022-1899"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Cellular & Molecular Immunology"],["dc.contributor.author","Hammerschmidt, Swantje I."],["dc.contributor.author","Bosnjak, Berislav"],["dc.contributor.author","Bernhardt, Günter"],["dc.contributor.author","Friedrichsen, Michaela"],["dc.contributor.author","Ravens, Inga"],["dc.contributor.author","Dopfer-Jablonka, Alexandra"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Behrens, Georg M. N."],["dc.contributor.author","Förster, Reinhold"],["dc.date.accessioned","2021-09-01T06:42:25Z"],["dc.date.available","2021-09-01T06:42:25Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1038/s41423-021-00755-z"],["dc.identifier.pii","755"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89048"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.eissn","2042-0226"],["dc.relation.issn","1672-7681"],["dc.title","Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","S2211124721008287"],["dc.bibliographiccitation.firstpage","109415"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cell Reports"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Hofmann-Winkler, Heike"],["dc.contributor.author","Krüger, Nadine"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Graichen, Luise"],["dc.contributor.author","Arora, Prerna"],["dc.contributor.author","Sidarovich, Anzhalika"],["dc.contributor.author","Moldenhauer, Anna-Sophie"],["dc.contributor.author","Winkler, Martin S."],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2021-09-01T06:42:36Z"],["dc.date.available","2021-09-01T06:42:36Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.celrep.2021.109415"],["dc.identifier.pii","S2211124721008287"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89097"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.issn","2211-1247"],["dc.title","SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","13863"],["dc.bibliographiccitation.issue","36"],["dc.bibliographiccitation.journal","Journal of Biological Chemistry"],["dc.bibliographiccitation.lastpage","13873"],["dc.bibliographiccitation.volume","293"],["dc.contributor.author","Zmora, Pawel"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Kollmus, Heike"],["dc.contributor.author","Moldenhauer, Anna-Sophie"],["dc.contributor.author","Danov, Olga"],["dc.contributor.author","Braun, Armin"],["dc.contributor.author","Winkler, Michael"],["dc.contributor.author","Schughart, Klaus"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2020-12-10T18:12:58Z"],["dc.date.available","2020-12-10T18:12:58Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1074/jbc.RA118.001273"],["dc.identifier.eissn","1083-351X"],["dc.identifier.issn","0021-9258"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74544"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Virology"],["dc.bibliographiccitation.volume","93"],["dc.contributor.author","Kleine-Weber, Hannah"],["dc.contributor.author","Elzayat, Mahmoud Tarek"],["dc.contributor.author","Wang, Lingshu"],["dc.contributor.author","Graham, Barney S."],["dc.contributor.author","Müller, Marcel A."],["dc.contributor.author","Drosten, Christian"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.editor","Gallagher, Tom"],["dc.date.accessioned","2020-12-10T18:37:02Z"],["dc.date.available","2020-12-10T18:37:02Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1128/JVI.01381-18"],["dc.identifier.eissn","1098-5514"],["dc.identifier.issn","0022-538X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76822"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Cell Research"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Jin, Yeonhwa"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2022-10-04T10:21:36Z"],["dc.date.available","2022-10-04T10:21:36Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1038/s41422-022-00713-y"],["dc.identifier.pii","713"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114454"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-600"],["dc.relation.eissn","1748-7838"],["dc.relation.iserratumof","/handle/2/83186"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Publisher Correction: Dalbavancin: novel candidate for COVID-19 treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","erratum_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","243"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cell Research"],["dc.bibliographiccitation.lastpage","244"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Jin, Yeonhwa"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2021-04-14T08:30:19Z"],["dc.date.available","2021-04-14T08:30:19Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1038/s41422-020-00459-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83186"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1748-7838"],["dc.relation.haserratum","/handle/2/114454"],["dc.relation.issn","1001-0602"],["dc.title","Dalbavancin: novel candidate for COVID-19 treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","S2352396421005557"],["dc.bibliographiccitation.firstpage","103761"],["dc.bibliographiccitation.journal","eBioMedicine"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Groß, Rüdiger"],["dc.contributor.author","Zanoni, Michelle"],["dc.contributor.author","Seidel, Alina"],["dc.contributor.author","Conzelmann, Carina"],["dc.contributor.author","Gilg, Andrea"],["dc.contributor.author","Krnavek, Daniela"],["dc.contributor.author","Erdemci-Evin, Sümeyye"],["dc.contributor.author","Mayer, Benjamin"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Müller, Janis A."],["dc.date.accessioned","2022-06-01T09:40:14Z"],["dc.date.available","2022-06-01T09:40:14Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.ebiom.2021.103761"],["dc.identifier.pii","S2352396421005557"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108671"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.issn","2352-3964"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]