Gágyor, Ildikó

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Family medicine & medical science research"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Bleidorn, Jutta"],["dc.contributor.author","Költzsch, C."],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.contributor.author","Gágyor, Ildikó"],["dc.contributor.author","Theile, G."],["dc.date.accessioned","2021-09-07T13:12:45Z"],["dc.date.available","2021-09-07T13:12:45Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.4172/2327-4972.1000122"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89304"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Family Physicians as Clinical Trial Investigators? - A Qualitative Study of Physicians’ Experiences with a Double-Blind Clinical Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1441"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Clinical Microbiology and Infection"],["dc.bibliographiccitation.lastpage","1447"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Gágyor, Ildikó"],["dc.contributor.author","Hummers, Eva"],["dc.contributor.author","Schmiemann, Guido"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Pfeiffer, Sebastian"],["dc.contributor.author","Afshar, Kambiz"],["dc.contributor.author","Bleidorn, Jutta"],["dc.date.accessioned","2021-08-16T09:08:13Z"],["dc.date.available","2021-08-16T09:08:13Z"],["dc.date.issued","2021-10"],["dc.description.abstract","Objective\r\n\r\nWe explored whether initial treatment with the herbal drug uva ursi (UU) reduces antibiotic use in women with uncomplicated urinary tract infection (UTI) without increasing symptom burden and complication frequency compared with antibiotic treatment.\r\nMethods\r\n\r\nA double-blind randomized controlled trial was conducted in 42 family practices in Germany. The participants were adult women with suspected uncomplicated UTIs receiving either UU 105 mg 3 × 2 tablets for 5 days (intervention) or fosfomycin a 3-g single dose (control), and their respective placebos. Participants and investigators were blinded. The primary outcome included (1) antibiotic courses day 0–28 as superiority, and (2) symptom burden (sum of daily symptom scores) day 0–7, as non-inferiority outcome (margin 125%). Clinicaltrials.gov: NCT03151603.\r\nResults\r\n\r\nOverall, 398 patients were randomly allocated to groups receiving UU (n = 207) and fosfomycin (n = 191). The number of antibiotic courses was 63.6% lower (95% CI 53.6%–71.4%; p < 0.0001) in the UU group than in the fosfomycin group. The ratio of total symptom burden in the UU group compared with control was 136.5% (95% CI 122.7–151.9; p 0.95), failing non-inferiority. Eight women developed pyelonephritis in the UU group compared with two in the fosfomycin group (mean difference 2.8; 95% CI 0.2–5.9; p 0.067). Adverse events were similar between the groups.\r\nDiscussion\r\n\r\nIn women with uncomplicated UTIs, initial treatment with UU reduced antibiotic use but led to a higher symptom burden and more safety concerns than fosfomycin."],["dc.identifier.doi","10.1016/j.cmi.2021.05.032"],["dc.identifier.pmid","34111592"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88709"],["dc.language.iso","en"],["dc.relation.eissn","1469-0691"],["dc.relation.issn","1198-743X"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.relation.orgunit","Institut für Medizinische Statistik"],["dc.title","Herbal treatment with uva ursi extract versus fosfomycin in women with uncomplicated urinary tract infection in primary care: a randomized controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","321"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Das Gesundheitswesen"],["dc.bibliographiccitation.lastpage","327"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Peters-Klimm, F."],["dc.contributor.author","Hermann, K."],["dc.contributor.author","Gagyor, Ildiko"],["dc.contributor.author","Haasenritter, Joerg"],["dc.contributor.author","Bleidorn, Jutta"],["dc.date.accessioned","2018-11-07T09:24:52Z"],["dc.date.available","2018-11-07T09:24:52Z"],["dc.date.issued","2013"],["dc.description.abstract","Objective: Clinical trials are regarded as complex due to the high demands on quality and patient safety and are still exceptional in German primary care. To optimise future trial planning, this study aimed at investigating the barriers and enablers experienced by primary care physicians (PCPs) for trial participation. Methods: PCPs were surveyed on 11 regional primary care medical education (CME) events using a standardised questionnaire. Regression analyses were used to identify predictors for future trial participation. Results: Of 804 invited PCPs, 408 (50.7%) participated in the survey (51 +/- 9 years, female 35%). 69% of participants could imagine their participation in a clinical trial. Of 12 potential factors assessed, the final model retained the 2 predictors (OR; CI; P-value) \"research questions relevant to practice\" (2.25; 1.61-3.14;<0.001) and \"new challenges/change from everyday life\" (2.24; 1.67-2.97; < 0.001). While 58% of participants were principally willing to participate in investigator training courses according to Good Clinical Practice (GCP), only 6% had participated in such training at the time of answering. Short events were preferred. Only 7% were willing to take over at least half of the costs of these courses. Conclusion: To enhance German PCPs motivation to participate in clinical trials, both trials and training courses should be tailored to the needs in the primary care setting."],["dc.identifier.doi","10.1055/s-0032-1321742"],["dc.identifier.isi","000321685200009"],["dc.identifier.pmid","22893207"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29932"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0941-3790"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Erfahrungen und Einstellungen zu Klinischen Studien in der Hausarztpraxis: Ergebnisse einer Befragung von deutschen Hausärzten"],["dc.title.alternative","Experiences and Attitudes Regarding Practice-Based Clinical Trials: Results of a Survey among German Primary Care Physicians"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","423"],["dc.bibliographiccitation.lastpage","427"],["dc.contributor.author","Schmiemann, Guido"],["dc.contributor.author","Bleidorn, Jutta"],["dc.contributor.author","Gágyor, Ildikó"],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.contributor.editor","Kochen, Michael M."],["dc.date.accessioned","2021-09-10T10:24:17Z"],["dc.date.available","2021-09-10T10:24:17Z"],["dc.date.issued","2012"],["dc.description.edition","4"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89329"],["dc.publisher","Thieme"],["dc.publisher.place","Stuttgart"],["dc.relation.isbn","978-3-13-141384-0"],["dc.relation.ispartof","Allgemeinmedizin und Familienmedizin"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Schmerzen beim Wasserlassen"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","134"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Zeitschrift für Allgemeinmedizin"],["dc.bibliographiccitation.lastpage","140"],["dc.bibliographiccitation.volume","90"],["dc.contributor.author","Bleidorn, Jutta"],["dc.contributor.author","Schmiemann, G."],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.contributor.author","Gágyor, Ildikó"],["dc.date.accessioned","2021-09-07T13:15:38Z"],["dc.date.available","2021-09-07T13:15:38Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.3238/zfa.2014.0134–0140"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89305"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Hausarzt und Prüfarzt? – Grundlagen und Entscheidungshilfen zu Arzneimittelstudien in der Allgemeinmedizin"],["dc.title.alternative","Family Doctor and Trial Investigator? Basics and Decision Aids for Drug Trials in Family Practice"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","i1172"],["dc.bibliographiccitation.journal","The BMJ"],["dc.bibliographiccitation.volume","352"],["dc.contributor.author","Bleidorn, Jutta"],["dc.contributor.author","Gagyor, Ildiko"],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.date.accessioned","2018-11-07T10:17:00Z"],["dc.date.available","2018-11-07T10:17:00Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1136/bmj.i1172"],["dc.identifier.isi","000371756500009"],["dc.identifier.pmid","26936753"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41147"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1756-1833"],["dc.title","Ibuprofen v fosfomycin for uncomplicated urinary tract infection"],["dc.title.subtitle","Authors’ reply to Kristiansen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","letter_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1124"],["dc.bibliographiccitation.journal","Geburtshilfe und Frauenheilkunde"],["dc.bibliographiccitation.lastpage","1125"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Bleidorn, Jutta"],["dc.contributor.author","Gágyor, Ildikó"],["dc.contributor.author","Schmiemann, Guido"],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.date.accessioned","2021-09-06T11:36:30Z"],["dc.date.available","2021-09-06T11:36:30Z"],["dc.date.issued","2016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89288"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Therapieempfehlungen: Antibiotika oder nichtantibiotische Therapie?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","327"],["dc.bibliographiccitation.issue","18"],["dc.bibliographiccitation.journal","Deutsches Ärzteblatt international"],["dc.bibliographiccitation.lastpage","328"],["dc.bibliographiccitation.volume","110"],["dc.contributor.author","Schmiemann, Guido"],["dc.contributor.author","Gagyor, Ildiko"],["dc.contributor.author","Hummers-Pradier, Eva"],["dc.contributor.author","Bleidorn, Jutta"],["dc.date.accessioned","2018-11-07T09:24:46Z"],["dc.date.available","2018-11-07T09:24:46Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.3238/arztebl.2013.0327c"],["dc.identifier.isi","000323158300006"],["dc.identifier.pmid","23720701"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29905"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1866-0452"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Methodological Flaws"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","letter_ja"],["dspace.entity.type","Publication"]]