Reisinger, Ellen

[["dc.bibliographiccitation.journal","European Psychiatry"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Palm, Ulrich"],["dc.contributor.author","Schiller, Christina"],["dc.contributor.author","Fintescu, Zoe"],["dc.contributor.author","Obermeier, Michael"],["dc.contributor.author","Keeser, Daniel"],["dc.contributor.author","Reisinger, E."],["dc.contributor.author","Pogarell, Oliver"],["dc.contributor.author","Nitsche, M."],["dc.contributor.author","Moeller, Hans-Juergen"],["dc.contributor.author","Padberg, Frank"],["dc.date.accessioned","2018-11-07T09:01:15Z"],["dc.date.available","2018-11-07T09:01:15Z"],["dc.date.issued","2011"],["dc.identifier.isi","000208641301252"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24374"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier France-editions Scientifiques Medicales Elsevier"],["dc.publisher.place","Paris"],["dc.relation.issn","0924-9338"],["dc.title","TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) OF THE PREFRONTAL CORTEX IN THERAPY-RESISTANT DEPRESSION: A DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","644"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","NeuroImage"],["dc.bibliographiccitation.lastpage","657"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Keeser, Daniel"],["dc.contributor.author","Padberg, Frank"],["dc.contributor.author","Reisinger, E."],["dc.contributor.author","Pogarell, Oliver"],["dc.contributor.author","Kirsch, V."],["dc.contributor.author","Palm, Ulrich"],["dc.contributor.author","Karch, Susanne"],["dc.contributor.author","Moeller, Hans-Juergen"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Mulert, Christoph"],["dc.date.accessioned","2018-11-07T08:58:09Z"],["dc.date.available","2018-11-07T08:58:09Z"],["dc.date.issued","2011"],["dc.description.abstract","Prefrontal transcranial direct current stimulation (tDCS) with the anode placed on the left dorsolateral prefrontal cortex (DLPFC) has been reported to enhance working memory in healthy subjects and to improve mood in major depression. However, its putative antidepressant cognitive and behavior action is not well understood. Here, we evaluated the distribution of neuronal electrical activity changes after anodal tDCS of the left DLPFC and cathodal tDCS of the right supraorbital region using spectral power analysis and standardized low resolution tomography (sLORETA). Ten healthy subjects underwent real and sham tDCS on separate days in a double-blind, placebo-controlled cross-over trial. Anodal tDCS was applied for 20 min at 2 mA intensity over the left DLPFC, while the cathode was positioned over the contralateral supraorbital region. After tDCS, EEG was recorded during an eyes-closed resting state followed by a working memory (n-back) task. Statistical non-parametric mapping showed reduced left frontal delta activity in the real tDCS condition. Specifically, a significant reduction of mean current densities (sLORETA) for the delta band was detected in the left subgenual PFC, the anterior cingulate and in the left medial frontal gyrus. Moreover, the effect was strongest for the first 5 min (p<0.01). The following n-back task revealed a positive impact of prefrontal tDCS on error rate, accuracy and reaction time. This was accompanied by increased P2- and P3- event-related potentials (ERP) component-amplitudes for the 2-back condition at the electrode Fz. A source localization using sLORETA for the time window 250-450 ms showed enhanced activity in the left parahippocampal gyrus for the 2-back condition. These results suggest that anodal tDCS of the left DLPFC and/or cathodal tDCS of the contralateral supraorbital region may modulate regional electrical activity in the prefrontal and anterior cingulate cortex in addition to improving working memory performance. (C) 2010 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.neuroimage.2010.12.004"],["dc.identifier.isi","000287556200024"],["dc.identifier.pmid","21146614"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23576"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1095-9572"],["dc.relation.issn","1053-8119"],["dc.title","Prefrontal direct current stimulation modulates resting EEG and event-related potentials in healthy subjects: A standardized low resolution tomography (sLORETA) study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","242"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","251"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Palm, Ulrich"],["dc.contributor.author","Schiller, Christina"],["dc.contributor.author","Fintescu, Zoe"],["dc.contributor.author","Obermeier, Michael"],["dc.contributor.author","Keeser, Daniel"],["dc.contributor.author","Reisinger, E."],["dc.contributor.author","Pogarell, Oliver"],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Moeller, H-J"],["dc.contributor.author","Padberg, Frank"],["dc.date.accessioned","2018-11-07T09:08:30Z"],["dc.date.available","2018-11-07T09:08:30Z"],["dc.date.issued","2012"],["dc.description.abstract","Background Anodal transcranial direct current stimulation (tDCS) of the prefrontal cortex has been proposed as therapeutic intervention in major depression. According to clinical needs, this study addresses the question whether tDCS is effective in treatment resistant major depressive episodes. Methods Twenty-two patients with a major depressive episode were randomly assigned to a cross-over protocol comparing tDCS and placebo stimulation add-on to a stable antidepressant medication. The parameters of active tDCS were: 1 or 2 mA for 20 minutes/day, anode over the left dorsolateral prefrontal cortex, cathode over the contralateral supraorbital region. Active and placebo tDCS was applied for 2 weeks using indistinguishable DC stimulators. Patients, raters, and operators were blinded to treatment conditions. Results There was no significant difference in depression scores after 2 weeks of real compared with 2 weeks of sham tDCS. Scores on the Hamilton Depression Rating Scale were reduced from baseline by 14.7% for active tDCS and 10% for placebo tDCS. In contrast, subjective mood ratings showed an increase in positive emotions after real tDCS compared with sham tDCS. Conclusions Anodal tDCS, applied for 2 weeks, was not superior to placebo treatment in patients with treatment resistant depression. However, secondary outcome measures are pointing to a positive effect of tDCS on emotions. Therefore, modified and improved tDCS protocols should be carried out in controlled pilot trials to develop tDCS towards an efficacious antidepressant intervention in therapy-resistant depression. (C) 2012 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.brs.2011.08.005"],["dc.identifier.isi","000307198700009"],["dc.identifier.pmid","21962978"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26044"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1935-861X"],["dc.title","Transcranial direct current stimulation in treatment resistant depression: A randomized double-blind, placebo-controlled study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]