Koziolek, Michael Johann

[["dc.bibliographiccitation.firstpage","e0222102"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Grupp, Clemens"],["dc.contributor.author","Troche-Polzien, Ilka"],["dc.contributor.author","Stock, Johanna"],["dc.contributor.author","Bramlage, Carsten"],["dc.contributor.author","Müller, Gerhard A."],["dc.contributor.author","Koziolek, Michael"],["dc.contributor.editor","Gonzalez Suarez, Maria Lourdes"],["dc.date.accessioned","2020-12-10T18:42:10Z"],["dc.date.available","2020-12-10T18:42:10Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1371/journal.pone.0222102"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16604"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77833"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","199"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Nephrology"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Delistefani, Fani"],["dc.contributor.author","Wallbach, Manuel"],["dc.contributor.author","Müller, Gerhard A"],["dc.contributor.author","Koziolek, Michael J"],["dc.contributor.author","Grupp, Clemens"],["dc.date.accessioned","2019-07-09T11:51:45Z"],["dc.date.available","2019-07-09T11:51:45Z"],["dc.date.issued","2019"],["dc.description.abstract","Abstract Background Due to rising vascular comorbidities of patients undergoing dialysis, the prevalence of permanent hemodialysis catheters as hemodialysis access is increasing. However, infection is a major complication of these catheters. Therefore, identification of potential predicting risk factors leading to early infection related complications is valuable, in particular the significance the CRP (C-reactive protein)-value is of interest. Methods In this retrospective study 151 permanent hemodialysis catheters implanted in 130 patients were examined. The following data were collected at the time of catheter implantation: CRP-value, history of catheter-related infection, microbiological status, immunosuppression and diabetes mellitus. The primary outcomes were recorded over the 3 months following the implantation: catheter-related infection, days of hospital stay and death. Catheter removal or revision, rehospitalization and use of antibiotics were identified as secondary outcomes. Results We identified a total of 27 (17.9%) infections (systemic infection: 2.26 episodes/ 1000 catheter days, local infection: 0.6 episodes/ 1000 catheter days). The development of an infection was independent of the CRP-value (p = 0.66) as well as the presence of diabetes mellitus (p = 0.64) or immunosuppression (p = 0.71). Univariate analysis revealed that infection was more frequent in patients with MRSA-carriage (p < 0.001), in case of previous catheter-related infection (p < 0.05) and of bacteremia or bacteriuria in the period of 3 months before catheter implantation (p < 0.001). Catheter removal or revision (p = 0.002), rehospitalization (p = 0.001) and use of antibiotics (p = 0.02) were also more often observed in patients with MRSA-carriage. Conclusions The CRP-value at the time of implantation of a permanent hemodialysis catheter is not associated with the development of early catheter related infections, but an individual history of catheter-related infection, MRSA-carriage and bacteremia or bacteriuria in the period of 3 months prior to catheter implantation are significant risk factors."],["dc.identifier.doi","10.1186/s12882-019-1392-0"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16186"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60004"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","BioMed Central"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Risk factors for catheter-related infections in patients receiving permanent dialysis catheter"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]