Lenk, Christian

[["dc.bibliographiccitation.firstpage","537"],["dc.bibliographiccitation.journal","Therapeutics and Clinical Risk Management"],["dc.bibliographiccitation.lastpage","546"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Lenk, Christian"],["dc.contributor.author","Duttge, Gunnar"],["dc.date.accessioned","2018-11-07T09:46:02Z"],["dc.date.available","2018-11-07T09:46:02Z"],["dc.date.issued","2014"],["dc.description.abstract","For more than 20 years the off-label use of drugs has been an essential part of the ethical and legal considerations regarding the international regulation of drug licensing. Despite a number of regulatory initiatives in the European Union, there seems to remain a largely unsatisfactory situation following a number of critical descriptions and statements from actors in the field. The present article gives an overview of the ethical and legal framework and developments in European countries and identifies existing problems and possible pathways for solutions in this important regulatory area. In addition to the presentation of the ethical and legal foundations, some attention is given to criticisms from medical practitioners to the current handling of off-label drug use. The review also focuses on the situation confronted by patients and physicians when off-label prescriptions are necessary. Through legal descriptions from a number of countries, possible solutions for future discussion of European health care policy are selected and explained."],["dc.identifier.doi","10.2147/TCRM.S40232"],["dc.identifier.isi","000338788000001"],["dc.identifier.pmid","25050064"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11881"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34773"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Dove Medical Press Ltd"],["dc.relation.issn","1178-203X"],["dc.rights","CC BY-NC 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/3.0"],["dc.title","Ethical and legal framework and regulation for off-label use: European perspective"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0198249"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Flatau, Laura"],["dc.contributor.author","Reitt, Markus"],["dc.contributor.author","Duttge, Gunnar"],["dc.contributor.author","Lenk, Christian"],["dc.contributor.author","Zoll, Barbara"],["dc.contributor.author","Poser, Wolfgang"],["dc.contributor.author","Weber, Alexandra"],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Rietschel, Marcella"],["dc.contributor.author","Strohmaier, Jana"],["dc.contributor.author","Kesberg, Rebekka"],["dc.contributor.author","Nagel, Jonas"],["dc.contributor.author","Schulze, Thomas G."],["dc.contributor.editor","DeAngelis, Margaret M."],["dc.date.accessioned","2020-12-10T18:42:07Z"],["dc.date.available","2020-12-10T18:42:07Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0198249"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15687"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77816"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Genomic information and a person’s right not to know: A closer look at variations in hypothetical informational preferences in a German sample"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","576"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics"],["dc.bibliographiccitation.lastpage","588"],["dc.bibliographiccitation.volume","180"],["dc.contributor.author","Lenk, Christian"],["dc.contributor.author","Duttge, Gunnar"],["dc.contributor.author","Flatau, Laura"],["dc.contributor.author","Frommeld, Debora"],["dc.contributor.author","Poser, Wolfgang"],["dc.contributor.author","Reitt, Markus"],["dc.contributor.author","Schulze, Thomas"],["dc.contributor.author","Weber, Alexandra"],["dc.contributor.author","Zoll, Barbara"],["dc.date.accessioned","2020-12-10T14:07:21Z"],["dc.date.available","2020-12-10T14:07:21Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/ajmg.b.32751"],["dc.identifier.eissn","1552-485X"],["dc.identifier.issn","1552-4841"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70183"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","A look into the future? Patients' and health care staff's perception and evaluation of genetic information and the right not to know"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]