Now showing 1 - 2 of 2
  • 2015Journal Article
    [["dc.bibliographiccitation.artnumber","018103"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Physical Review Letters"],["dc.bibliographiccitation.volume","114"],["dc.contributor.author","Gholami, A."],["dc.contributor.author","Steinbock, Oliver"],["dc.contributor.author","Zykov, Vladimir"],["dc.contributor.author","Bodenschatz, Eberhard"],["dc.date.accessioned","2018-11-07T10:02:21Z"],["dc.date.available","2018-11-07T10:02:21Z"],["dc.date.issued","2015"],["dc.description.abstract","We report experiments on flow-driven waves in a microfluidic channel containing the signaling slime mold Dictyostelium discoideum. The observed cyclic adenosine monophosphate (cAMP) wave trains developed spontaneously in the presence of flow and propagated with the velocity proportional to the imposed flow velocity. The period of the wave trains was independent of the flow velocity. Perturbations of flow-driven waves via external periodic pulses of the signaling agent cAMP induced 1 : 1, 2 : 1, 3 : 1, and 1 : 2 frequency responses, reminiscent of Arnold tongues in forced oscillatory systems. We expect our observations to be generic to active media governed by reaction-diffusion-advection dynamics, where spatially bound autocatalytic processes occur under flow conditions."],["dc.identifier.doi","10.1103/PhysRevLett.114.018103"],["dc.identifier.isi","000352068300026"],["dc.identifier.pmid","25615506"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12790"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38204"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Physical Soc"],["dc.relation.issn","1079-7114"],["dc.relation.issn","0031-9007"],["dc.relation.orgunit","Fakultät für Physik"],["dc.rights","CC BY 3.0"],["dc.subject.mesh","Cyclic AMP"],["dc.subject.mesh","Dictyostelium"],["dc.subject.mesh","Microfluidic Analytical Techniques"],["dc.subject.mesh","Models, Biological"],["dc.subject.mesh","Signal Transduction"],["dc.title","Flow-Driven Waves and Phase-Locked Self-Organization in Quasi-One-Dimensional Colonies of Dictyostelium discoideum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2014Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","2662"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.lastpage","2673"],["dc.bibliographiccitation.volume","107"],["dc.contributor.author","Priebe, Marius"],["dc.contributor.author","Bernhardt, Marten"],["dc.contributor.author","Blum, Christoph"],["dc.contributor.author","Tarantola, Marco"],["dc.contributor.author","Bodenschatz, Eberhard"],["dc.contributor.author","Salditt, Tim"],["dc.date.accessioned","2017-09-07T11:45:22Z"],["dc.date.available","2017-09-07T11:45:22Z"],["dc.date.issued","2014"],["dc.description.abstract","We have performed scanning x-ray nanobeam diffraction experiments on single cells of the amoeba Dictyostelium discoideum. Cells have been investigated in 1), freeze-dried, 2), frozen-hydrated (vitrified), and 3), initially alive states. The spatially resolved small-angle x-ray scattering signal shows characteristic streaklike patterns in reciprocal space, which we attribute to fiber bundles of the actomyosin network. From the intensity distributions, an anisotropy parameter can be derived that indicates pronounced local variations within the cell. In addition to nanobeam small-angle x-ray scattering, we have evaluated the x-ray differential phase contrast in view of the projected electron density. Different experimental aspects of the x-ray experiment, sample preparation, and data analysis are discussed. Finally, the x-ray results are correlated with optical microscopy (differential phase contrast and confocal microscopy of mutant strains with fluorescently labeled actin and myosin II), which have been carried out in live and fixed states, including optical microscopy under cryogenic conditions."],["dc.identifier.doi","10.1016/j.bpj.2014.10.027"],["dc.identifier.fs","606778"],["dc.identifier.gro","3142000"],["dc.identifier.isi","000345859500026"],["dc.identifier.pmid","25468345"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/12127"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3434"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Deutsche Forschungsgemeinschaft [A11]; Sonderforschungsbereich [937]"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.eissn","1542-0086"],["dc.relation.issn","0006-3495"],["dc.relation.orgunit","Institut für Röntgenphysik"],["dc.relation.orgunit","Fakultät für Physik"],["dc.relation.workinggroup","RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc-nd/3.0/"],["dc.subject.gro","x-ray scattering"],["dc.subject.mesh","Anisotropy"],["dc.subject.mesh","Cell Survival"],["dc.subject.mesh","Dictyostelium"],["dc.subject.mesh","Nanoparticles"],["dc.subject.mesh","Scattering, Small Angle"],["dc.subject.mesh","Software"],["dc.subject.mesh","X-Ray Diffraction"],["dc.title","Scanning X-Ray Nanodiffraction on Dictyostelium discoideum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS