Now showing 1 - 8 of 8
  • 2017-02Journal Article
    [["dc.bibliographiccitation.firstpage","40"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","American Journal of Dentistry"],["dc.bibliographiccitation.lastpage","46"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","MĂĽller, Marion"],["dc.contributor.author","Schmickler, Jan"],["dc.contributor.author","Rinke, Sven"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2018-10-10T09:05:29Z"],["dc.date.available","2018-10-10T09:05:29Z"],["dc.date.issued","2017-02"],["dc.description.abstract","This randomized clinical study compared the influence of manual and power toothbrushes on clinical and microbiological findings in initial treatment of periodontitis."],["dc.fs.pkfprnr","918"],["dc.identifier.fs","632945"],["dc.identifier.pmid","29178713"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15928"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Influence of manual and power toothbrushes on clinical and microbiological findings in initial treatment of periodontitis - A randomized clinical study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.artnumber","39"],["dc.bibliographiccitation.journal","BMC Geriatrics"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Ziebolz, Dirk"],["dc.contributor.author","Werner, Christine"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Nitschke, Ina"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Chenot, Jean-Francois"],["dc.date.accessioned","2018-11-07T10:28:13Z"],["dc.date.available","2018-11-07T10:28:13Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: This study was performed to assess oral and nutritional status of nursing home residents in a region of Lower Saxony, Germany. The aim was to show potential associations between oral status (dentate or edentulous), further anamnestic factors (dementia, age, smoking) and the risk for malnutrition in this population. Methods: In this observational cross-sectional pilot study of residents from four nursing homes Mini Nutritional Assessment (MNA), Body-Mass-Index (BMI), dental status (DMF-T) and periodontal situation (PSR (R)/PSI) were recorded. Associations of recorded factors with oral health and nutritional status were examined in univariate and multivariate analysis. Results: Eighty-seven residents participated in the study (mean age: 84.1 years; female: 72%, demented: 47%). Average BMI was 26.2 kg/m(2); according MNA 52% were at risk for malnutrition. 48% of the residents were edentulous, and the average DMF-T of dentulous was 25.0 (3.7) (D-T: 2.0 [3.1], M-T: 15.0 [8.3], F-T: 8.0 [7.4]); PSR (R)/PSI 3 and 4 (need for periodontal treatment) showed 79% of residents. In univariate analysis dementia (OR 2.5 CI95 1.1-5.6) but not being edentulous (OR 2.0 CI95 0.8-5.8) were associated with being at risk for malnutrition. Dementia remained associated in multivariate analysis adjusting for age and sex, (OR 3.1 CI95 1.2-8.2) and additionally being edentulous (OR 2.8 CI95 1.1-7.3) became associated significantly. Furthermore, nursing home residents with dementia had more remaining teeth (OR 2.5 CI95 1.1-5.9). Conclusion: Dementia was a stronger predictor for risk of malnutrition in nursing home residents than being edentulous. Further studies to elucidate the possible role of oral health as cofactor for malnutrition in dementia are needed."],["dc.identifier.doi","10.1186/s12877-017-0429-0"],["dc.identifier.isi","000396944800002"],["dc.identifier.pmid","28143415"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14208"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43377"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1471-2318"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Oral Health and nutritional status in nursing home residents-results of an explorative cross-sectional pilot study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","322"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Drug and Chemical Toxicology"],["dc.bibliographiccitation.lastpage","330"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Schmidt, J."],["dc.contributor.author","Zyba, Vitalij"],["dc.contributor.author","Jung, K."],["dc.contributor.author","Rinke, Sven"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2018-11-07T10:11:46Z"],["dc.date.available","2018-11-07T10:11:46Z"],["dc.date.issued","2016"],["dc.description.abstract","Objectives: This study compared the cytotoxicity of a new octenidine mouth rinse (MR) against gingival fibroblasts and epithelial cells with different established MRs. Methods: The following MRs were used: Octenidol (OCT), Chlorhexidine 0.2% (CHX), Listerine (LIS), Meridol (MER), Betaisodona (BET); and control (medium only). Human primary gingiva fibroblasts and human primary nasal epithelial cells were cultivated in cell-specific media (2 x 10(5) cells/ml) and treated with MR for 1, 5, and 15 min. Each test was performed 12 times. Metabolism activity was measured using a cytotoxicity assay. A cellometer analyzed cell viability, cell number, and cell diameter. The data were analyzed by two-way analysis of variance with subsequent Dunnett's test and additional t-tests. Results: The cytotoxic effects of all MRs on fibroblasts and epithelial cells compared to the control depended on the contact time (p < 0.001). OCT and BET showed less influence on cell metabolism in fibroblasts than other MRs. OCT also demonstrated comparable but not significant results in epithelial cells (p > 0.005). Cell numbers of both cell types at all contact times revealed that OCT showed a less negative effect (p > 0.005), especially for epithelial cells compared to CHX after 15 min (p < 0.005). OCT and BET showed the best results for viability in fibroblasts (p > 0.005), but MER showed less influence than OCT in epithelial cells (p < 0.005). Conclusions: OCT is a potential alternative to CHX regarding cytotoxicity because of its lower cell-toxic effect against fibroblasts and epithelial cells."],["dc.identifier.doi","10.3109/01480545.2015.1121274"],["dc.identifier.isi","000373934300013"],["dc.identifier.pmid","26654138"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40108"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Taylor & Francis Ltd"],["dc.relation.issn","1525-6014"],["dc.relation.issn","0148-0545"],["dc.title","Cytotoxic effects of octenidine mouth rinse on human fibroblasts and epithelial cells - an in vitro study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","186"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","International Dental Journal"],["dc.bibliographiccitation.lastpage","193"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Schiffers, Nora"],["dc.contributor.author","Schwabe, Sandra"],["dc.contributor.author","Vasko, Radovan"],["dc.contributor.author","Mueller, Georg Anton"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2018-11-07T10:23:21Z"],["dc.date.available","2018-11-07T10:23:21Z"],["dc.date.issued","2017"],["dc.description.abstract","ObjectiveThe aim of this cross-sectional study was to evaluate the dental and periodontal health, as well as the microbiological and salivary conditions, of patients with and without diabetes mellitus (DM) who are receiving haemodialysis. MethodsOne-hundred and fifty-nine haemodialysis patients were included and divided into groups according to the pre-existing diabetes status: DM or no DM. The oral examination included dental findings and assessment of the periodontal situation. The periodontal condition was classified as healthy/mild, moderate or severe periodontitis. Subgingival biofilm samples were analysed using the polymerase chain reaction. The salivary diagnostics included measurement of unstimulated and stimulated salivary flow, pH and buffer capacity. Statistical analyses used Fisher's test, the t-test and the Mann-Whitney U-test ( = 5%). ResultsThe dental findings showed no significant difference between patients with and without DM (P = 0.44). The prevalence of periodontitis was high (96% in patients with DM and 97% in patients who did not have DM) and there was no significant difference between the groups (P = 0.71). There was a higher prevalence of Porphyromonas gingivalis, Parvimonas micros, Eubacterium nucleatum and Capnocytophaga spp. in patients without DM (P < 0.05). The salivary pH was significantly higher in patients without DM (P < 0.01). ConclusionWhile differences in the prevalence of periodontal pathogenic bacteria and in the salivary pH were detected between the groups, the dental and periodontal status was comparable between patients with and without DM. Accordingly, DM appears to have no decisive influence on the oral health in patients treated with haemodialysis who have well-controlled diabetes."],["dc.identifier.doi","10.1111/idj.12282"],["dc.identifier.isi","000402135100007"],["dc.identifier.pmid","28547773"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42439"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Wiley"],["dc.relation.issn","1875-595X"],["dc.relation.issn","0020-6539"],["dc.title","Dental and periodontal health, and microbiological and salivary conditions in patients with or without diabetes undergoing haemodialysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","E35"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Operative Dentistry"],["dc.bibliographiccitation.lastpage","E43"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Hellwig, Frank H."],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Schneider, H."],["dc.contributor.author","Krause, Felix"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2020-12-10T18:43:47Z"],["dc.date.available","2020-12-10T18:43:47Z"],["dc.date.issued","2017"],["dc.description.abstract","Objective: The aim of this study was to investigate dentin protection of different desensitizing varnishes (light- and self-curing) during acid action/abrasion stress and thermocyclic loading in vitro. Methods: Dentin discs of 2 mm thickness were cut from 120 human molars, embedded, and polished. Specimens were randomized into five groups (n=24): A, negative control; B, Gluma Desensitizer; C, Cervitec plus (self-curing); D, Seal & Protect; and E, Admira Protect (lightcuring). In groups B-E, varnish was applied on two-thirds of the dentin surface, and one-third acted as internal control. Stress cycle (2 cycles/day) for specimens were as follows: 1, acid action (pH: 2.9: five minutes); 2, remineralization (synthetic saliva: 60 minutes); 3, brushing (100 strokes); 4, thermocycling (five cycles); and 5, remineralization (synthetic saliva: six hours) for each group (n=12) for 30 (15 days) or 60 times (30 days). Specimens were analyzed using an incident light microscope. Substance loss was measured in micrometers. Statistical analysis was performed with the multiple contrast test (p < 0.05). Results: Groups B and C had a significantly lower dentin loss than A (p < 0.01). After 30 days, group A showed the highest dentin loss (p < 0.01), whereas the other groups lacked a significant difference regarding their substance loss (dentin and/or varnish; p > 0.05). Varnish layer loss was shown for groups D and E with a remaining protective layer; groups A-C showed dentin removal. Conclusion: All four varnishes are protective compared with an untreated control. Light-curing varnishes might provide higher dentin protection than self-curing materials."],["dc.identifier.doi","10.2341/16-068-L"],["dc.identifier.eissn","1559-2863"],["dc.identifier.isi","000391725100016"],["dc.identifier.issn","0361-7734"],["dc.identifier.pmid","27802119"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78228"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Operative Dentistry Inc"],["dc.relation.issn","1559-2863"],["dc.relation.issn","0361-7734"],["dc.title","Dentin Protection of Different Desensitizing Varnishes During Stress Simulation: An In Vitro Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","368"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Periodontology"],["dc.bibliographiccitation.lastpage","379"],["dc.bibliographiccitation.volume","88"],["dc.contributor.author","Schmickler, Jan"],["dc.contributor.author","Rupprecht, Annegret"],["dc.contributor.author","Patschan, Susann A."],["dc.contributor.author","Patschan, Daniel"],["dc.contributor.author","Mueller, Georg Anton"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Kottmann, Tanja"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2018-11-07T10:25:46Z"],["dc.date.available","2018-11-07T10:25:46Z"],["dc.date.issued","2017"],["dc.description.abstract","Background: This study evaluates periodontal conditions and microbiologic findings and their influence on rheumatologic disease parameters in patients with rheumatoid arthritis (RA). Methods: One hundred and sixty-eight patients with RA were included. A healthy control group (HC, n = 168) was composed according to age, sex, and smoking habits. Rheumatologic data (duration of illness, Disease Activity Score 28, rheumatic factor [RF], anti-cyclic citrullinated peptide [aCCP], medications) were extracted from patients' records. Dental examination included: 1) dental findings (decayed, missing, and/or filled adult teeth [DMF-T] index); 2) gingival inflammation (papillary bleeding index [PBI]); and 3) periodontal status (probing depth [PD], attachment loss [AL]). Periodontal condition was classified as healthy/mild, moderate, or severe periodontitis. Subgingival biofilm was analyzed regarding 11 periodontopathogenic bacteria. Statistical analyses included: 1) Kolmogorov-Smirnov test; 2) MannWhitney U test; 3) Pearson x(2) test; 4) Kruskal-Wallis test; and 5) regression analysis; level of significance alpha = 5%. Results: Mean DMF-T was significantly higher in patients with RA (19.3 +/- 4.8) than in HC group (16.9 +/- 5.8), especially owing to number of missing teeth (RA = 6.0 +/- 5.4, HC = 3.1 +/- 3.3; P < 0.01). Patients with RA had a significantly higher proportion of increased PD (P < 0.01) and AL compared with HC group (P < 0.01). Moderate to severe periodontitis was noted in 98% of patients with RA and 82% of the HC group (P < 0.01). RF-positive patients with RA suffered from worse periodontal conditions than RF-negative patients (P = 0.01). Age, PBI, and presence of Treponema denticola (P < 0.03) are related to periodontal condition in patients with RA. Although not statistically significant, Porphyromonas gingivalis and Fusobacterium nucleatum occur in higher concentrations more often in aCCP-positive patients with RA (P = 0.06). Conclusions: Patients with RA had worse periodontal conditions than HC participants. Although a trend for higher F. nucleatum and P. gingivalis concentrations in aCCP-positive patients with RA was found, importance of periodontal pathogenic bacteria and rheumatoid parameters in the interrelationship between periodontitis and RA remains unclear."],["dc.identifier.doi","10.1902/jop.2016.160355"],["dc.identifier.isi","000398260300009"],["dc.identifier.pmid","27858553"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42921"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Amer Acad Periodontology"],["dc.relation.issn","1943-3670"],["dc.relation.issn","0022-3492"],["dc.title","Cross-Sectional Evaluation of Periodontal Status and Microbiologic and Rheumatoid Parameters in a Large Cohort of Patients With Rheumatoid Arthritis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","2661"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Clinical Oral Investigations"],["dc.bibliographiccitation.lastpage","2670"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Mühlberg, Sophia"],["dc.contributor.author","Jäger, Jatina"],["dc.contributor.author","Krohn-Grimberghe, Bernhard"],["dc.contributor.author","Patschan, Susann"],["dc.contributor.author","Mausberg, Rainer F."],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Ziebolz, Dirk"],["dc.date.accessioned","2020-12-10T14:11:01Z"],["dc.date.available","2020-12-10T14:11:01Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00784-017-2068-4"],["dc.identifier.eissn","1436-3771"],["dc.identifier.issn","1432-6981"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70945"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Oral health-related quality of life depending on oral health in patients with rheumatoid arthritis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","197"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","International Dental Journal"],["dc.bibliographiccitation.lastpage","203"],["dc.bibliographiccitation.volume","68"],["dc.contributor.author","Ziebolz, Dirk"],["dc.contributor.author","Reiss, Lucie"],["dc.contributor.author","Schmalz, Gerhard"],["dc.contributor.author","Krause, Felix"],["dc.contributor.author","Haak, Rainer"],["dc.contributor.author","Mausberg, Rainer F."],["dc.date.accessioned","2020-12-10T18:28:50Z"],["dc.date.available","2020-12-10T18:28:50Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1111/idj.12353"],["dc.identifier.issn","0020-6539"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76427"],["dc.language.iso","fr"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Different views of dentists and general medical practitioners on dental care for patients with diabetes mellitus and coronary heart diseases: results of a questionnaire-based survey in a district of Germany"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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