Schild, Detlev

[["dc.bibliographiccitation.artnumber","014022"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Biomedical Optics"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Weigel, Arwed"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Zeug, Andre"],["dc.date.accessioned","2018-11-07T08:34:48Z"],["dc.date.available","2018-11-07T08:34:48Z"],["dc.date.issued","2009"],["dc.description.abstract","The essential feature of the confocal laser scanning microscope (cLSM) is the generation of optical sections by the removal of out-of-focus light. About ten years ago, structured illumination microscopy (SIM) was introduced as an alternative method for obtaining optical sections from biological specimens. Here we compare the resolution of the ApoTome (commercial SIM by Zeiss) to that achieved by a cLSM (Zeiss LSM 510). If fluorescent beads are used as test objects, then the ApoTome will achieve a lower axial resolution than the cLSM. In contrast to that, its lateral resolution scores slightly better. If subresolution homogeneous fluorescent layers are used as test objects, then the ApoTome will achieve a higher axial resolution than the cLSM. The ApoTome's axial resolution is homogeneous over the field-of-view while that of the cLSM changes markedly. Finally, the anisotropy of the ApoTome's resolution was found to be negligible for standard applications while its capability to resolve fine structures within stained tissue slices is limited to one or two cell layers and thus worse than in the cLSM. (C) 2009 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3083439]"],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft"],["dc.identifier.doi","10.1117/1.3083439"],["dc.identifier.isi","000264551900027"],["dc.identifier.pmid","19256710"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7767"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17904"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Spie-soc Photoptical Instrumentation Engineers"],["dc.relation.issn","1083-3668"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Resolution in the ApoTome and the confocal laser scanning microscope: comparison"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","140"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Neuroscience Methods"],["dc.bibliographiccitation.lastpage","147"],["dc.bibliographiccitation.volume","167"],["dc.contributor.author","Manzini, Ivan"],["dc.contributor.author","Schweer, Tina-Saskia"],["dc.contributor.author","Schild, Detlev"],["dc.date.accessioned","2018-11-07T11:19:01Z"],["dc.date.available","2018-11-07T11:19:01Z"],["dc.date.issued","2008"],["dc.description.abstract","ATP-binding cassette (ABC) transporters are a family of transmembrane proteins that, also known as multidrug resistance proteins, transport a wide variety of substrates across biological membranes in an energy-dependent manner. Recently it has been shown that members of this protein family interfere with fluorescent (calcium indicator) dye uptake in taste buds of rat and in cells in the olfactory epithelium of larval Xenopus laevis, including olfactory receptor neurons. It has, however, not been resolved whether this effect only serves to extrude xenobiotics in sensory taste and olfactory cells, or alternatively, whether it is a more general feature of many central nervous system neurons. In the latter case blocking these transporters would improve fluorescent dye uptake in general. Here we show, by means of cell imaging. that also neurons of the olfactory bulb express multidrug resistance transporters, whereby a marked inhomogeneity among cells in the main and accessory olfactory bulb was observed. Blocking these transporters improved the net uptake of fluorescent dyes not only in cell somata of the olfactory bulb, but especially in fine neuronal structures such as individual dendrites or olfactory glomeruli, which consist of a tangle of tiny neuronal processes. We therefore suggest that the expression of multidrug resistance proteins may be common in cells of the central nervous system, and that the application of specific transport inhibitors could generally improve fluorescent dye uptake in brain slices, thereby improving calcium imaging conditions. (c) 2007 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.jneumeth.2007.07.018"],["dc.identifier.isi","000252938400002"],["dc.identifier.pmid","17767961"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9767"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55173"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","0165-0270"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Improved fluorescent (calcium indicator) dye uptake in brain slices by blocking multidrug resistance transporters"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1452"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","FEBS Letters"],["dc.bibliographiccitation.lastpage","1458"],["dc.bibliographiccitation.volume","586"],["dc.contributor.author","Junek, Stephan"],["dc.contributor.author","Engelke, Michael"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Wienands, Juergen"],["dc.date.accessioned","2018-11-07T09:10:18Z"],["dc.date.available","2018-11-07T09:10:18Z"],["dc.date.issued","2012"],["dc.description.abstract","Antigen-induced B cell activation requires mobilization of the Ca2+ second messenger. This process is associated with the subcellular relocalization of signal effector proteins of the B cell antigen receptor such as the adaptor protein SLP65. Here we describe a broadly applicable live cell imaging method to simultaneously visualize intracellular Ca2+ flux profiles and the translocation of cytosolic signaling proteins to the plasma membrane in real time. Our approach delineated the kinetic hierarchy of Ca2+ signaling events in B cells and revealed a timely ordered contribution of various organelles to the overall Ca2+ signal. The developed experimental setup provides a useful tool to resolve the spatiotemporal signaling dynamics in various receptor signaling systems. (c) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.febslet.2012.03.057"],["dc.identifier.isi","000304104200011"],["dc.identifier.pmid","22673510"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9753"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26456"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0014-5793"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Spatiotemporal resolution of Ca2+ signaling events by real time imaging of single B cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1614"],["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","Glia"],["dc.bibliographiccitation.lastpage","1624"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Hassenklover, Thomas"],["dc.contributor.author","Kurtanska, Silvia"],["dc.contributor.author","Bartoszek, Ilonka"],["dc.contributor.author","Junek, Stephan"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Manzini, Ivan"],["dc.date.accessioned","2018-11-07T11:09:09Z"],["dc.date.available","2018-11-07T11:09:09Z"],["dc.date.issued","2008"],["dc.description.abstract","Extracellular purines and pyrimidines are important Signaling molecules acting via purinergic cell-surface receptors in neurons, glia, and glia-like cells such as sustentacular supporting cells (SCs) of the olfactory epithelium (OE). Here, we thoroughly characterize ATP-induced responses in SCs of the OE using functional Ca(2+) image The initial ATP-induced increase of the intracellular Ca(2+) concentration [Ca(2+)](i) always occurred in the apical part of SCs and subsequently propagated toward the basal lamina, indicating the occurrence of purinergic receptors I the apical part of SCs. The mean propagation velocity of the Ca(2+) signal within SCs was 17.10 +/- 1.02 mu m/s. ATP evoked increases in [Ca(2+)](i) in both the presence and absence of extracellular Ca(2+). Depletion of the intracellular Ca(2+) stores abolished the responses. This shows that the ATP-induced [Ca(2+)](i) increases were in large part, if not entirely, due to the activation of G protein-coupled receptors followed by Ca(2+) mobilization from intracellular stores, suggesting an involvement of P2Y receptors. The order of potency of the applied purinergic agonists was UTP > ATP > ATP-gamma S (with all others being only weakly active or inactive). The ATP-induced [Ca(2+)](i) increases could be reduced by the purinergic antagonists PPADS and RB2, but not by suramin. Our findings suggest that extracellular nucleotides in the OE activate SCs via P2Y(2)/P2Y(4)-like receptors and initiate a characteristic intraepithelial Ca(2+) wave. (C) 2008 Wiley-Liss, Inc."],["dc.description.sponsorship","DFG Research Center"],["dc.identifier.doi","10.1002/glia.20714"],["dc.identifier.isi","000260918100002"],["dc.identifier.pmid","18551628"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7757"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52943"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0894-1491"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Nucleotide-Induced Ca(2+) Signaling in Sustentacular Supporting Cells of the Olfactory Epithelium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2401"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","2406"],["dc.bibliographiccitation.volume","106"],["dc.contributor.author","Chen, Tsai-Wen"],["dc.contributor.author","Lin, Bei-Jung"],["dc.contributor.author","Schild, Detlev"],["dc.date.accessioned","2018-11-07T08:32:42Z"],["dc.date.available","2018-11-07T08:32:42Z"],["dc.date.issued","2009"],["dc.description.abstract","Odor representation in the olfactory bulb (OB) undergoes a transformation from a combinatorial glomerular map to a distributed mitral/tufted (M/T) cell code. To understand this transformation, we analyzed the odor representation in large populations of individual M/T cells in the Xenopus OB. The spontaneous [Ca(2+)] activities of M/T cells appeared to be irregular, but there were groups of spatially distributed neurons showing synchronized [Ca(2+)] activities. These neurons were always connected to the same glomerulus. Odorants elicited complex spatiotemporal response patterns in M/T cells where nearby neurons generally showed little correlation. But the responses of neurons connected to the same glomerulus were virtually identical, irrespective of whether the responses were excitatory or inhibitory, and independent of the distance between them. Synchronous neurons received correlated EPSCs and were coupled by electrical conductances that could account for the correlated responses. Thus, at the output stage of the OB, odors are represented by modules of distributed and synchronous M/T cells associated with the same glomeruli. This allows for parallel input to higher brain centers."],["dc.identifier.doi","10.1073/pnas.0810151106"],["dc.identifier.isi","000263516100058"],["dc.identifier.pmid","19181842"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6317"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17398"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Odor coding by modules of coherent mitral/tufted cells in the vertebrate olfactory bulb"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e39628"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Alevra, Mihai"],["dc.contributor.author","Schwartz, Peter J."],["dc.contributor.author","Schild, Detlev"],["dc.date.accessioned","2018-11-07T09:08:14Z"],["dc.date.available","2018-11-07T09:08:14Z"],["dc.date.issued","2012"],["dc.description.abstract","The diffusion coefficient of fluorescein in detached cilia of Xenopus laevis olfactory receptor neurons was measured using spatially-resolved FRAP, where the dye along half of the ciliary length was photobleached and its spatiotemporal fluorescence redistribution recorded. Fitting a one-dimensional numerical simulation of diffusion and photobleaching for 35 cilia resulted in a mean value of the diffusion coefficient (1.20 +/- 0.23).10(-10)m(2)/s and thus a reduction by a factor of 3.4 compared to free diffusion in aqueous solution."],["dc.identifier.doi","10.1371/journal.pone.0039628"],["dc.identifier.isi","000306355500012"],["dc.identifier.pmid","22808046"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7862"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25983"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","Direct Measurement of Diffusion in Olfactory Cilia Using a Modified FRAP Approach"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2611"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.lastpage","2619"],["dc.bibliographiccitation.volume","101"],["dc.contributor.author","Agte, Silke"],["dc.contributor.author","Junek, Stephan"],["dc.contributor.author","Matthias, Sabrina"],["dc.contributor.author","Ulbricht, Elke"],["dc.contributor.author","Erdmann, Ines"],["dc.contributor.author","Wurm, Antje"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Kaes, Josef A."],["dc.contributor.author","Reichenbach, Andreas"],["dc.date.accessioned","2018-11-07T08:48:58Z"],["dc.date.available","2018-11-07T08:48:58Z"],["dc.date.issued","2011"],["dc.description.abstract","In vertebrate eyes, images are projected onto an inverted retina where light passes all retinal layers on its way to the photoreceptor cells. Light scattering within this tissue should impair vision. We show that radial glial (Muller) cells in the living retina minimize intraretinal light scatter and conserve the diameter of a beam that hits a single Muller cell endfoot. Thus, light arrives at individual photoreceptors with high intensity. This leads to an optimized signal/noise ratio, which increases visual sensitivity and contrast. Moreover, we show that the ratio between Muller cells and cones-responsible for acute vision-is roughly 1. This suggests that high spatiotemporal resolution may be achieved by each cone receiving its part of the image via its individual Muller cell-light guide."],["dc.identifier.doi","10.1016/j.bpj.2011.09.062"],["dc.identifier.isi","000297897300010"],["dc.identifier.pmid","22261048"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7621"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21342"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","0006-3495"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Muller Glial Cell-Provided Cellular Light Guidance through the Vital Guinea-Pig Retina"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e21026"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Eifler, Jakob"],["dc.contributor.author","Martinelli, Eugenio"],["dc.contributor.author","Santonico, Marco"],["dc.contributor.author","Capuano, Rosamaria"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Di Natale, Corrado"],["dc.date.accessioned","2018-11-07T08:55:08Z"],["dc.date.available","2018-11-07T08:55:08Z"],["dc.date.issued","2011"],["dc.description.abstract","Fungal infestation on wheat is an increasingly grave nutritional problem in many countries worldwide. Fusarium species are especially harmful pathogens due to their toxic metabolites. In this work we studied volatile compounds released by F. cerealis, F. graminearum, F. culmorum and F. redolens using SPME-GC/MS. By using an electronic nose we were able to differentiate between infected and non-infected wheat grains in the post-harvest chain. Our electronic nose was capable of distinguishing between four wheat Fusaria species with an accuracy higher than 80%."],["dc.identifier.doi","10.1371/journal.pone.0021026"],["dc.identifier.isi","000291612900046"],["dc.identifier.pmid","21695232"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7620"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22833"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","Differential Detection of Potentially Hazardous Fusarium Species in Wheat Grains by an Electronic Nose"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e90500"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Bao, Guobin"],["dc.contributor.author","Schild, Detlev"],["dc.date.accessioned","2018-11-07T09:42:40Z"],["dc.date.available","2018-11-07T09:42:40Z"],["dc.date.issued","2014"],["dc.description.abstract","The parameters of experimentally obtained exponentials are usually found by least-squares fitting methods. Essentially, this is done by minimizing the mean squares sum of the differences between the data, most often a function of time, and a parameter-defined model function. Here we delineate a novel method where the noisy data are represented and analyzed in the space of Legendre polynomials. This is advantageous in several respects. First, parameter retrieval in the Legendre domain is typically two orders of magnitude faster than direct fitting in the time domain. Second, data fitting in a low-dimensional Legendre space yields estimates for amplitudes and time constants which are, on the average, more precise compared to least-squares-fitting with equal weights in the time domain. Third, the Legendre analysis of two exponentials gives satisfactory estimates in parameter ranges where least-squares-fitting in the time domain typically fails. Finally, filtering exponentials in the domain of Legendre polynomials leads to marked noise removal without the phase shift characteristic for conventional lowpass filters."],["dc.identifier.doi","10.1371/journal.pone.0090500"],["dc.identifier.isi","000332483600058"],["dc.identifier.pmid","24603904"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10017"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34009"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Fast and Accurate Fitting and Filtering of Noisy Exponentials in Legendre Space"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","10599"],["dc.bibliographiccitation.issue","41"],["dc.bibliographiccitation.journal","Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","10613"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Dudanova, Irina"],["dc.contributor.author","Sedej, Simon"],["dc.contributor.author","Ahmad, Mohiuddin"],["dc.contributor.author","Masius, Henriette"],["dc.contributor.author","Sargsyan, Vardanush"],["dc.contributor.author","Zhang, W."],["dc.contributor.author","Riedel, Dietmar"],["dc.contributor.author","Angenstein, Frank"],["dc.contributor.author","Schild, Detlev"],["dc.contributor.author","Rupnik, Marjan"],["dc.contributor.author","Missler, Markus"],["dc.date.accessioned","2018-11-07T09:06:58Z"],["dc.date.available","2018-11-07T09:06:58Z"],["dc.date.issued","2006"],["dc.description.abstract","alpha-Neurexins constitute a family of neuronal cell surface molecules that are essential for efficient neurotransmission, because mice lacking two or all three alpha-neurexin genes show a severe reduction of synaptic release. Although analyses of alpha-neurexin knock-outs and transgenic rescue animals suggested an involvement of voltage-dependent Ca2+ channels, it remained unclear whether alpha-neurexins have a general role in Ca2+-dependent exocytosis and how they may affect Ca2+ channels. Here we show by membrane capacitance measurements from melanotrophs in acute pituitary gland slices that release from endocrine cells is diminished by > 50% in adult alpha-neurexin double knock-out and newborn triple knock-out mice. There is a reduction of the cell volume in mutant melanotrophs; however, no ultrastructural changes in size or intracellular distribution of the secretory granules were observed. Recordings of Ca2+ currents from melanotrophs, transfected human embryonic kidney cells, and brainstem neurons reveal that alpha-neurexins do not affect the activation or inactivation properties of Ca2+ channels directly but may be responsible for coupling them to release-ready vesicles and metabotropic receptors. Our data support a general and essential role for alpha-neurexins in Ca2+-triggered exocytosis that is similarly important for secretion from neurons and endocrine cells."],["dc.identifier.doi","10.1523/JNEUROSCI.1913-06.2006"],["dc.identifier.isi","000241192800034"],["dc.identifier.pmid","17035546"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7751"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25679"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Soc Neuroscience"],["dc.relation.issn","0270-6474"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]