Now showing 1 - 4 of 4
  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","436"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Central European Journal of Medicine"],["dc.bibliographiccitation.lastpage","442"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Bergmann, Ingo"],["dc.contributor.author","Heetfeld, Maximilian"],["dc.contributor.author","Crozier, Thomas A."],["dc.contributor.author","Schafdecker, Hans G."],["dc.contributor.author","Poeschl, Rupert"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Popov, Aron-Frederik"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Hinz, Jose Maria"],["dc.date.accessioned","2018-11-07T09:22:14Z"],["dc.date.available","2018-11-07T09:22:14Z"],["dc.date.issued","2013"],["dc.description.abstract","Outpatient surgery is increasingly being performed on patients with pre-existing cardiovascular and pulmonary disorders. These are relevant for anesthesia because of the inherent risk of hemodynamic instability. This study compared the hemodynamic course in ASA III patients undergoing knee arthroscopy with either peripheral block of the femoral and sciatic nerves or general anesthesia. We searched our patient database for ASA III patients who had undergone knee arthroscopy between 2005 and 2010. This is routinely performed in either regional or general anesthesia, and the patients were stratified according to the anesthetic. Hemodynamic parameters, process times, complications and postoperative pain documented in the charts were evaluated and compared. 130 ASA III outpatients underwent knee arthroscopy during the observation period. Regional anesthesia alone (n=65) was sufficient in 96%. Heart rate was more stable and blood pressure decreased less under regional than under general anesthesia (systolic pressure - 11 +/- 8% versus - 28 +/- 9%; p < 0.001). Patients with general anesthesia (n=65) required more circulatory support. Establishing the nerve block takes longer than inducing general anesthesia, but this was performed ahead of time and thus had no effect on work flow. The groups did not differ with regard to complication rates, and intensity of postoperative pain or satisfaction with the anesthetic. No patient showed evidence of nerve damage or neurological deficits. Peripheral nerve block provides a more stable hemodynamic course than general anesthesia in ASA III patients undergoing knee arthroscopy. (C) Versita Sp. z o.o."],["dc.identifier.doi","10.2478/s11536-012-0143-4"],["dc.identifier.isi","000320283200013"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29292"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Versita"],["dc.relation.issn","1644-3640"],["dc.relation.issn","1895-1058"],["dc.title","Peripheral nerve blocks give greater hemodynamic stability than general anesthesia for ASA III patients undergoing outpatient knee arthroscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2008Journal Article
    [["dc.bibliographiccitation.firstpage","217"],["dc.bibliographiccitation.issue","7-8"],["dc.bibliographiccitation.journal","Wiener klinische Wochenschrift"],["dc.bibliographiccitation.lastpage","223"],["dc.bibliographiccitation.volume","120"],["dc.contributor.author","Wiese, Christoph Hermann"],["dc.contributor.author","Bartels, Utz"],["dc.contributor.author","Bergmann, Anke K."],["dc.contributor.author","Bergmann, Ingo"],["dc.contributor.author","Bahr, Jan"],["dc.contributor.author","Graf, Bernhard Martin"],["dc.date.accessioned","2018-11-07T11:17:01Z"],["dc.date.available","2018-11-07T11:17:01Z"],["dc.date.issued","2008"],["dc.description.abstract","In 2005 the European Resuscitation Council published new guidelines for advanced life support. One of the issues was to reduce the \"no flow time\", which is defined as the time without chest compression in the first period of cardiac arrest. In a manikin study, we evaluated whether using the laryngeal tube instead of endotracheal intubation for airway management during cardiac arrest could reduce the \"no flow time\". METHODS: The study was prospective and included 50 volunteers who performed standardized management of simulated cardiac arrest in a manikin. All participants had completed an obligatory course in emergency medicine but had not been specifically trained in endotracheal intubation; they were therefore designated as unfamiliar in using the endotracheal tube to secure the airway, in accordance with the definition of the European Resuscitation Council. We defined two groups for the study: the LT group, who used the laryngeal tube to secure the airway; and the ET group, who used the endotracheal tube and bag-mask ventilation to ventilate the manikin. The participants were initially randomly assigned to one of the groups and thereafter completed the other scenario. Study endpoints were the total \"no flow time\" and adherence to guidelines of the European Resuscitation Council. RESULTS: Use of the laryngeal tube during cardiac arrest in the manikin significantly reduced the \"no flow time\" when compared with endotracheal intubation (109.3 s vs. 190.4 s; P < 0.01). The laryngeal tube was inserted significantly faster than the endotracheal tube (13 s vs. 52 s; P < 0.01) and was correctly positioned by 98% of the participants at the first attempt, compared with 72% using the endotracheal tube. CONCLUSION: With regard to the guidelines of the European Resuscitation Council, we are convinced that during cardiac arrest supraglottic airway devices should be used by emergency personnel unfamiliar with endotracheal intubation."],["dc.identifier.doi","10.1007/s00508-008-0953-1"],["dc.identifier.isi","000256178400006"],["dc.identifier.pmid","18500596"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54717"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.issn","1613-7671"],["dc.relation.issn","0043-5325"],["dc.title","Using a laryngeal tube during cardiac arrest reduces \"no flow time\" in a manikin study: a comparison between laryngeal tube and endotracheal tube"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.journal","Critical Care Medicine"],["dc.contributor.author","Thair, Simone"],["dc.contributor.author","Mewes, Caspar"],["dc.contributor.author","Hinz, José"],["dc.contributor.author","Bergmann, Ingo"],["dc.contributor.author","Büttner, Benedikt"],["dc.contributor.author","Sehmisch, Stephan"],["dc.contributor.author","Meissner, Konrad"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Sweeney, Timothy E."],["dc.contributor.author","Mansur, Ashham"],["dc.date.accessioned","2021-06-01T10:46:57Z"],["dc.date.available","2021-06-01T10:46:57Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1097/CCM.0000000000005027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85430"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","0090-3493"],["dc.title","Gene Expression–Based Diagnosis of Infections in Critically Ill Patients—Prospective Validation of the SepsisMetaScore in a Longitudinal Severe Trauma Cohort"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","638"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Investigative Medicine"],["dc.bibliographiccitation.lastpage","643"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Mansur, Ashham"],["dc.contributor.author","Hinz, José"],["dc.contributor.author","Hillebrecht, Bronja"],["dc.contributor.author","Bergmann, Ingo"],["dc.contributor.author","Popov, Aron Frederik"],["dc.contributor.author","Ghadimi, Michael"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Beissbarth, Tim"],["dc.contributor.author","Mihm, Sabine"],["dc.date.accessioned","2021-06-01T10:48:39Z"],["dc.date.available","2021-06-01T10:48:39Z"],["dc.date.issued","2014"],["dc.description.abstract","Background Sepsis is a life-threatening condition. Programmed cell death 1 protein (PD-1), a negative costimulatory molecule, is suggested to be involved in pathogenesis as mortality is associated with high expression and as neutralizing antibodies improve survival in a mouse model. The PD-1 gene harbors an intronic single-nucleotide polymorphism, rs11568821, which is located in a transcription factor-binding site and supposed to affect PD-1 transcription. Objective This study aimed at investigating whether mortality (90-day) among patients with sepsis associates with PD-1 rs11568821 genotypes. Methods Adult white patients with sepsis from the surgical intensive care units of a university medical center were followed up for 90 days, and mortality was recorded as primary outcome variable. Blood samples were taken for PD-1 rs11568821 genotyping. Sequential Organ Failure Assessment scores increased at enrollment and during the observation period to monitor morbidity. Results Two hundred nineteen critically ill patients with sepsis were enrolled in this investigation. Ninety-day mortality was significantly higher among G homozygotes than among A allele carriers (P = 0.0032). During intensive care unit stay, G homozygotes experienced higher Sequential Organ Failure Assessment scores (P < 0.001) and a higher demand of vasopressor therapy (P = 0.0107). Conclusions Data provide first associative evidence for PD-1 rs11568821 as a prognostic indicator in patients with sepsis."],["dc.identifier.doi","10.2310/JIM.0000000000000059"],["dc.identifier.isi","000332039500006"],["dc.identifier.pmid","24463978"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86007"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.eissn","1708-8267"],["dc.relation.issn","1081-5589"],["dc.title","Ninety-Day Survival Rate of Patients With Sepsis Relates to Programmed Cell Death 1 Genetic Polymorphism rs11568821"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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