Schmidt, Christian

[["dc.bibliographiccitation.firstpage","1011"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","1021"],["dc.bibliographiccitation.volume","70"],["dc.contributor.author","Waeschle, Reiner M."],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Mörstedt, Antje-Britta"],["dc.date.accessioned","2022-01-11T14:05:22Z"],["dc.date.available","2022-01-11T14:05:22Z"],["dc.date.issued","2021"],["dc.description.abstract","Zusammenfassung Hintergrund und Ziel der Arbeit In dieser Studie wurden die Studierenden der Generationen Y und Z des Studiengangs Humanmedizin an der Georg-August-Universität Göttingen hinsichtlich ihrer Präferenzen am Arbeitsplatz und der Wahl eines Arbeitgebers befragt. Material und Methoden Die Befragung wurde 2016 über einen Onlinefragebogen über EvaSys an 2637 Studierende der Universitätsmedizin Göttingen versandt und wurde von 742 beantwortet (Rücklaufquote: 28,1 %). Ergebnisse Die Befragten fühlten sich unabhängig von der Generationszugehörigkeit mit 89,5 % überwiegend „gut“ und „nicht so gut“ auf den Übergang von der Universität ins Berufsleben vorbereitet. Die häufigsten Ängste waren viel Arbeit/wenig Freizeit, Zeitmangel bei der Patientenversorgung, mangelnde Erfahrung, Stress, fachliche Überforderung und schlechte Einarbeitung. Die Beschaffung von Informationen über zukünftige Arbeitgeber erfolgte in beiden Gruppen überwiegend mit knapp 60 % über die Homepage des Krankenhauses. Wichtig waren den Studierenden eine besonders gute Ausbildung und eine strukturierte Einarbeitung/ein strukturiertes Weiterbildungscurriculum. Diskussion Die Weiterentwicklung eines strukturierten Einarbeitungskonzepts für Berufseinsteiger, ein verbindliches, strukturiertes Weiterbildungscurriculum, die Etablierung bzw. Weiterentwicklung eines Mentoring-Programms, die Weiterentwicklung von Führungsqualitäten und die Gestaltung einer ansprechenden und aktualisierten Homepage sind wesentliche Voraussetzungen, um auf dem hart umkämpften Fachkräftemarkt zukünftig erfolgreich zu sein."],["dc.description.abstract","Abstract Background and objective In this study medical students of the generations Y and Z at the Georg-August University Göttingen were asked about their preferences in the workplace and the choice of an employer. Material and methods In 2016, the survey was sent to 2637 students at the University Medical Center Göttingen using an online questionnaire via EvaSys and was answered by 742 (response rate: 28.1%). Results Regardless of the generation, with 89.5% the respondents felt predominantly “well” and “not so well” prepared for the transition from university to professional life. The most common fears were a lot of work/little free time, lack of time in patient care, lack of experience, stress, excessive technical demands and poor familiarization. In both groups almost 60% obtained information about future employers via the hospital’s website. It was important for the students to have a particularly good education and a structured induction/advanced training curriculum. Conclusion The further development of a structured induction concept for young professionals, a binding and structured further training curriculum, the establishment or further development of a mentoring program, the further development of leadership skills and the design of an appealing and updated website are essential prerequisites for future success in the highly competitive skilled labor market."],["dc.description.abstract","Zusammenfassung Hintergrund und Ziel der Arbeit In dieser Studie wurden die Studierenden der Generationen Y und Z des Studiengangs Humanmedizin an der Georg-August-Universität Göttingen hinsichtlich ihrer Präferenzen am Arbeitsplatz und der Wahl eines Arbeitgebers befragt. Material und Methoden Die Befragung wurde 2016 über einen Onlinefragebogen über EvaSys an 2637 Studierende der Universitätsmedizin Göttingen versandt und wurde von 742 beantwortet (Rücklaufquote: 28,1 %). Ergebnisse Die Befragten fühlten sich unabhängig von der Generationszugehörigkeit mit 89,5 % überwiegend „gut“ und „nicht so gut“ auf den Übergang von der Universität ins Berufsleben vorbereitet. Die häufigsten Ängste waren viel Arbeit/wenig Freizeit, Zeitmangel bei der Patientenversorgung, mangelnde Erfahrung, Stress, fachliche Überforderung und schlechte Einarbeitung. Die Beschaffung von Informationen über zukünftige Arbeitgeber erfolgte in beiden Gruppen überwiegend mit knapp 60 % über die Homepage des Krankenhauses. Wichtig waren den Studierenden eine besonders gute Ausbildung und eine strukturierte Einarbeitung/ein strukturiertes Weiterbildungscurriculum. Diskussion Die Weiterentwicklung eines strukturierten Einarbeitungskonzepts für Berufseinsteiger, ein verbindliches, strukturiertes Weiterbildungscurriculum, die Etablierung bzw. Weiterentwicklung eines Mentoring-Programms, die Weiterentwicklung von Führungsqualitäten und die Gestaltung einer ansprechenden und aktualisierten Homepage sind wesentliche Voraussetzungen, um auf dem hart umkämpften Fachkräftemarkt zukünftig erfolgreich zu sein."],["dc.description.abstract","Abstract Background and objective In this study medical students of the generations Y and Z at the Georg-August University Göttingen were asked about their preferences in the workplace and the choice of an employer. Material and methods In 2016, the survey was sent to 2637 students at the University Medical Center Göttingen using an online questionnaire via EvaSys and was answered by 742 (response rate: 28.1%). Results Regardless of the generation, with 89.5% the respondents felt predominantly “well” and “not so well” prepared for the transition from university to professional life. The most common fears were a lot of work/little free time, lack of time in patient care, lack of experience, stress, excessive technical demands and poor familiarization. In both groups almost 60% obtained information about future employers via the hospital’s website. It was important for the students to have a particularly good education and a structured induction/advanced training curriculum. Conclusion The further development of a structured induction concept for young professionals, a binding and structured further training curriculum, the establishment or further development of a mentoring program, the further development of leadership skills and the design of an appealing and updated website are essential prerequisites for future success in the highly competitive skilled labor market."],["dc.identifier.doi","10.1007/s00101-021-01026-2"],["dc.identifier.pii","1026"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97651"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","1432-055X"],["dc.relation.issn","0003-2417"],["dc.title","Die Generationen Y und Z – Neue Herausforderungen für Führungskräfte im Krankenhaus"],["dc.title.translated","Generations Y and Z—New challenges for hospital leadership"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","710"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Alzheimer's & Dementia: The Journal of the Alzheimer's Association"],["dc.bibliographiccitation.lastpage","719"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Llorens, Franc"],["dc.contributor.author","Kruse, Niels"],["dc.contributor.author","Schmitz, Matthias"],["dc.contributor.author","Gotzmann, Nadine"],["dc.contributor.author","Golanska, Ewa"],["dc.contributor.author","Thüne, Katrin"],["dc.contributor.author","Zejneli, Orgeta"],["dc.contributor.author","Kanata, Eirini"],["dc.contributor.author","Knipper, Tobias"],["dc.contributor.author","Cramm, Maria"],["dc.contributor.author","Lange, Peter"],["dc.contributor.author","Zafar, Saima"],["dc.contributor.author","Sikorska, Beata"],["dc.contributor.author","Liberski, Pawel P."],["dc.contributor.author","Mitrova, Eva"],["dc.contributor.author","Varges, Daniela"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Sklaviadis, Theodoros"],["dc.contributor.author","Mollenhauer, Brit"],["dc.contributor.author","Zerr, Inga"],["dc.date.accessioned","2018-10-08T13:38:00Z"],["dc.date.available","2018-10-08T13:38:00Z"],["dc.date.issued","2017-06"],["dc.description.abstract","Accurate diagnosis of prion diseases and discrimination from alternative dementias gain importance in the clinical routine, but partial overlap in cerebrospinal fluid (CSF) biomarkers impedes absolute discrimination in the differential diagnostic context. We established the clinical parameters for prion disease diagnosis for the quantification of CSF α-synuclein in patients with sporadic (n = 234) and genetic (n = 56) prion diseases, in cases with cognitive impairment/dementia or neurodegenerative disease (n = 278), and in the neurologic control group (n = 111). An optimal cutoff value of 680 pg/mL α-synuclein results in 94% sensitivity and 96% specificity when diagnosing sporadic Creutzfeldt-Jakob disease (CJD). Genetic CJD cases showed increased CSF α-synuclein values. No increased α-synuclein levels were detected in non-CJD cases with rapid progression course. Detection of α-synuclein in the CSF of patients with suspected CJD is a valuable diagnostic test reaching almost full discrimination from non-prion disease cases. These data highlight the utility of CSF α-synuclein quantification in front of classical CSF biomarkers in clinical routine."],["dc.fs.pkfprnr","61006"],["dc.identifier.doi","10.1016/j.jalz.2016.09.013"],["dc.identifier.fs","631450"],["dc.identifier.pmid","27870938"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15884"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1552-5279"],["dc.title","Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","54"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","American Journal of Alzheimer's Disease and Other Dementias"],["dc.bibliographiccitation.lastpage","60"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Becker, Harry"],["dc.contributor.author","Zerr, Inga"],["dc.date.accessioned","2021-06-01T10:47:55Z"],["dc.date.available","2021-06-01T10:47:55Z"],["dc.date.issued","2014"],["dc.description.abstract","Background/Objective: Apolipoprotein E (apoE) plays an important role in the pathogenesis of Alzheimer’s disease (AD). Altered cerebrospinal fluid (CSF) and plasma levels have been previously reported in patients with AD. We hypothesized that CSF apoE levels of patients with newly diagnosed AD might be associated with their cognitive performance. Methods: Patients with AD (N = 71) enrolled into an observational study underwent neuropsychological testing (Consortium to Establish a Registry for AD [CERAD] plus) at time of diagnosis. The CSF was obtained, and apoE concentrations were determined. Generalized linear models were constructed to assess the associations of apoE and neuropsychological measures while adjusting for important potential confounders. Results: No association of CSF apoE levels and cognitive function could be demonstrated. Still, the use of neuroleptic drugs, female gender, preprogression time, and lower education were linked to worse cognitive function in some domains. Conclusion: The CSF apoE appears not to be suitable as a biochemical surrogate of cognitive function in AD under the given circumstances. By means of longitudinal analyses, potential associations with the velocity of decline will be investigated in the near future."],["dc.identifier.doi","10.1177/1533317513505133"],["dc.identifier.isi","000331463000009"],["dc.identifier.pmid","24277910"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85765"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Inc"],["dc.relation.eissn","1938-2731"],["dc.relation.issn","1533-3175"],["dc.title","Cerebrospinal Fluid Apolipoprotein E Concentration and Severity of Cognitive Impairment in Patients With Newly Diagnosed Alzheimer’s Disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","902"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Geophysical Research. G, Biogeosciences"],["dc.bibliographiccitation.lastpage","922"],["dc.bibliographiccitation.volume","123"],["dc.contributor.author","Newcomer, Michelle E."],["dc.contributor.author","Hubbard, Susan S."],["dc.contributor.author","Fleckenstein, Jan H."],["dc.contributor.author","Maier, Ulrich"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Thullner, Martin"],["dc.contributor.author","Ulrich, Craig"],["dc.contributor.author","Flipo, Nicolas"],["dc.contributor.author","Rubin, Yoram"],["dc.date.accessioned","2020-12-10T14:06:24Z"],["dc.date.available","2020-12-10T14:06:24Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/jgrg.v123.3"],["dc.identifier.issn","2169-8953"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69883"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Influence of Hydrological Perturbations and Riverbed Sediment Characteristics on Hyporheic Zone Respiration of CO 2 and N 2"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","7506"],["dc.bibliographiccitation.issue","15_suppl"],["dc.bibliographiccitation.journal","Journal of Clinical Oncology"],["dc.bibliographiccitation.lastpage","7506"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Pfreundschuh, Michael"],["dc.contributor.author","Christofyllakis, Konstantinos"],["dc.contributor.author","Altmann, Bettina"],["dc.contributor.author","Ziepert, Marita"],["dc.contributor.author","Haenel, Mathias"],["dc.contributor.author","Viardot, Andreas"],["dc.contributor.author","Neubauer, Andreas"],["dc.contributor.author","Held, Gerhard"],["dc.contributor.author","Truemper, Lorenz"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Kanz, Lothar"],["dc.contributor.author","Hallek, Michael J."],["dc.contributor.author","Schmitz, Norbert"],["dc.contributor.author","Heintges, Tobias"],["dc.contributor.author","Koelbel, Christian"],["dc.contributor.author","Schneider, Guenther"],["dc.contributor.author","Ruebe, Christian"],["dc.contributor.author","Hellwig, Dirk"],["dc.contributor.author","Poeschel, Viola"],["dc.contributor.author","Murawski, Niels"],["dc.date.accessioned","2020-12-10T18:41:33Z"],["dc.date.available","2020-12-10T18:41:33Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1200/JCO.2017.35.15_suppl.7506"],["dc.identifier.eissn","1527-7755"],["dc.identifier.issn","0732-183X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77611"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Radiotherapy to bulky disease PET-negative after immunochemotherapy in elderly DLBCL patients: Results of a planned interim analysis of the first 187 patients with bulky disease treated in the OPTIMAL>60 study of the DSHNHL."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","271"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","273"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Lyudmilov, Cristina"],["dc.contributor.author","Petersone, Daina"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Bösel, Julian"],["dc.contributor.author","Rösche, Johannes"],["dc.date.accessioned","2021-04-14T08:26:39Z"],["dc.date.available","2021-04-14T08:26:39Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1097/WNP.0000000000000683"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82029"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0736-0258"],["dc.title","Breach Rhythm May Be Suppressed as a Form of Todd's Paralysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1124"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Archives of Neurology"],["dc.bibliographiccitation.lastpage","1130"],["dc.bibliographiccitation.volume","68"],["dc.contributor.author","Schmidt, Christian"],["dc.date.accessioned","2021-06-01T10:49:02Z"],["dc.date.available","2021-06-01T10:49:02Z"],["dc.date.issued","2011"],["dc.description.abstract","Different rates of progression have been observed among patients with Alzheimer disease. Risk factors that accelerate deterioration have been identified and some are being discussed, such as genetics, comorbidity, and the early appearance of Alzheimer disease motor signs. Progressive forms of Alzheimer disease have been reported with rapid cognitive decline and disease duration of only a few years. This short review aims to provide an overview of the current knowledge of rapidly progressive Alzheimer disease. Furthermore, we suggest that rapid, in this context, should be defined as a Mini-Mental State Examination score decrease of 6 points per year. Arch Neurol. 201.1;68(9):1124-1130"],["dc.identifier.doi","10.1001/archneurol.2011.189"],["dc.identifier.isi","000294693200003"],["dc.identifier.pmid","21911694"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86140"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Medical Assoc"],["dc.relation.issn","0003-9942"],["dc.title","Rapidly Progressive Alzheimer Disease"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1385"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Alzheimer's Disease"],["dc.bibliographiccitation.lastpage","1393"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Karch, André"],["dc.contributor.author","Llorens, Franc"],["dc.contributor.author","Schmitz, Matthias"],["dc.contributor.author","Arora, Amandeep Singh"],["dc.contributor.author","Zafar, Saima"],["dc.contributor.author","Lange, Peter"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Zerr, Inga"],["dc.date.accessioned","2020-12-10T18:44:09Z"],["dc.date.available","2020-12-10T18:44:09Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.3233/JAD-160267"],["dc.identifier.eissn","1875-8908"],["dc.identifier.issn","1387-2877"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78349"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Stratification by Genetic and Demographic Characteristics Improves Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers in Rapidly Progressive Dementia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e648"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","The Lancet Haematology"],["dc.bibliographiccitation.lastpage","e657"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Zoellner, Anna-Katharina"],["dc.contributor.author","Unterhalt, Michael"],["dc.contributor.author","Stilgenbauer, Stephan"],["dc.contributor.author","Hübel, Kai"],["dc.contributor.author","Thieblemont, Catherine"],["dc.contributor.author","Metzner, Bernd"],["dc.contributor.author","Topp, Max"],["dc.contributor.author","Truemper, Lorenz"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Bouabdallah, Kamal"],["dc.contributor.author","Hoster, Eva"],["dc.date.accessioned","2021-10-01T09:58:44Z"],["dc.date.available","2021-10-01T09:58:44Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/S2352-3026(21)00195-2"],["dc.identifier.pii","S2352302621001952"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90131"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.relation.issn","2352-3026"],["dc.title","Long-term survival of patients with mantle cell lymphoma after autologous haematopoietic stem-cell transplantation in first remission: a post-hoc analysis of an open-label, multicentre, randomised, phase 3 trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","781"],["dc.bibliographiccitation.issue","Supplement 1"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.lastpage","781"],["dc.bibliographiccitation.volume","132"],["dc.contributor.author","Poeschel, Viola"],["dc.contributor.author","Held, Gerhard"],["dc.contributor.author","Ziepert, Marita"],["dc.contributor.author","Altmann, Bettina"],["dc.contributor.author","Witzens-Harig, Mathias"],["dc.contributor.author","Holte, Harald"],["dc.contributor.author","Thurner, Lorenz"],["dc.contributor.author","Viardot, Andreas"],["dc.contributor.author","Borchmann, Peter"],["dc.contributor.author","Kanz, Lothar"],["dc.contributor.author","Keller, Ulrich"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Mahlberg, Rolf"],["dc.contributor.author","Metzner, Bernd"],["dc.contributor.author","Marks, Reinhard"],["dc.contributor.author","Hoeffkes, Heinz-Gert"],["dc.contributor.author","Christofyllakis, Konstantinos"],["dc.contributor.author","Amam, Josif"],["dc.contributor.author","Berdel, Christian"],["dc.contributor.author","Stilgenbauer, Stephan"],["dc.contributor.author","Schmitz, Norbert"],["dc.contributor.author","Truemper, Lorenz"],["dc.contributor.author","Murawski, Niels"],["dc.contributor.author","Loeffler, Markus"],["dc.contributor.author","Pfreundschuh, Michael"],["dc.date.accessioned","2020-12-10T18:38:43Z"],["dc.date.available","2020-12-10T18:38:43Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1182/blood-2018-99-112403"],["dc.identifier.eissn","1528-0020"],["dc.identifier.issn","0006-4971"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77420"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Excellent Outcome of Young Patients (18-60 years) with Favourable-Prognosis Diffuse Large B-Cell Lymphoma (DLBCL) Treated with 4 Cycles CHOP Plus 6 Applications of Rituximab: Results of the 592 Patients of the Flyer Trial of the Dshnhl/GLA"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]