Schmidt, Christian

[["dc.bibliographiccitation.firstpage","6298"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","International Journal of Molecular Sciences"],["dc.bibliographiccitation.volume","21"],["dc.contributor.affiliation","Podlesniy, Petar; \t\t \r\n\t\t Neurobiology Unit, Institut d’Investigacions Biomèdiques de Barcelona (CSIC), 08036 Barcelona, Spain, ppodlesniy@gmail.com\t\t \r\n\t\t Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08036 Barcelona, Spain, ppodlesniy@gmail.com"],["dc.contributor.affiliation","Llorens, Franc; \t\t \r\n\t\t Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08036 Barcelona, Spain, franc.llorens@gmail.com\t\t \r\n\t\t Bellvitge Biomedical Research Institute (IBIDELL), 08908 L’Hospitalet de Llobregat, Spain, franc.llorens@gmail.com\t\t \r\n\t\t Department of Neurology, Clinical Dementia Center, University Medical School, Georg-August University, 37075 Göttingen, Germany, franc.llorens@gmail.com"],["dc.contributor.affiliation","Puigròs, Margalida; \t\t \r\n\t\t Neurobiology Unit, Institut d’Investigacions Biomèdiques de Barcelona (CSIC), 08036 Barcelona, Spain, puigrosserra.m@gmail.com\t\t \r\n\t\t Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08036 Barcelona, Spain, puigrosserra.m@gmail.com"],["dc.contributor.affiliation","Serra, Nuria; \t\t \r\n\t\t Neurobiology Unit, Institut d’Investigacions Biomèdiques de Barcelona (CSIC), 08036 Barcelona, Spain, serranuri@gmail.com\t\t \r\n\t\t Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08036 Barcelona, Spain, serranuri@gmail.com"],["dc.contributor.affiliation","Sepúlveda-Falla, Diego; \t\t \r\n\t\t Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany, d.sepulveda-falla@uke.uni-hamburg.de"],["dc.contributor.affiliation","Schmidt, Christian; \t\t \r\n\t\t Department of Neurology, Clinical Dementia Center, University Medical School, Georg-August University, 37075 Göttingen, Germany, Christian.Schmidt@medizin.uni-goettingen.de\t\t \r\n\t\t German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany, Christian.Schmidt@medizin.uni-goettingen.de"],["dc.contributor.affiliation","Hermann, Peter; \t\t \r\n\t\t Department of Neurology, Clinical Dementia Center, University Medical School, Georg-August University, 37075 Göttingen, Germany, peter.hermann@med.uni-goettingen.de\t\t \r\n\t\t German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany, peter.hermann@med.uni-goettingen.de"],["dc.contributor.affiliation","Zerr, Inga; \t\t \r\n\t\t Department of Neurology, Clinical Dementia Center, University Medical School, Georg-August University, 37075 Göttingen, Germany, IngaZerr@med.uni-goettingen.de\t\t \r\n\t\t German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany, IngaZerr@med.uni-goettingen.de"],["dc.contributor.affiliation","Trullas, Ramon; \t\t \r\n\t\t Neurobiology Unit, Institut d’Investigacions Biomèdiques de Barcelona (CSIC), 08036 Barcelona, Spain, ramon.trullas@iibb.csic.es\t\t \r\n\t\t Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08036 Barcelona, Spain, ramon.trullas@iibb.csic.es\t\t \r\n\t\t Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain, ramon.trullas@iibb.csic.es"],["dc.contributor.author","Podlesniy, Petar"],["dc.contributor.author","Llorens, Franc"],["dc.contributor.author","Puigròs, Margalida"],["dc.contributor.author","Serra, Nuria"],["dc.contributor.author","Sepúlveda-Falla, Diego"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Hermann, Peter"],["dc.contributor.author","Zerr, Inga"],["dc.contributor.author","Trullas, Ramon"],["dc.date.accessioned","2021-04-14T08:32:33Z"],["dc.date.available","2021-04-14T08:32:33Z"],["dc.date.issued","2020"],["dc.date.updated","2022-09-07T00:35:16Z"],["dc.identifier.doi","10.3390/ijms21176298"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83949"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1422-0067"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Cerebrospinal Fluid Mitochondrial DNA in Rapid and Slow Progressive Forms of Alzheimer’s Disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","74"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Beiträge zur Geschichte der deutschen Sprache und Literatur"],["dc.bibliographiccitation.lastpage","106"],["dc.bibliographiccitation.volume","140"],["dc.contributor.author","Schmidt, Christian"],["dc.date.accessioned","2020-12-10T18:42:18Z"],["dc.date.available","2020-12-10T18:42:18Z"],["dc.date.issued","2018"],["dc.description.abstract","AbstractThis article presents a manuscript that was transferred from the Hamburg Franciscan monastery to the Hamburg Beguin convent around the year 1500. The manuscript connects treatises, meditations and prayers of the late medieval Ars moriendi by using cross references, rubrics and intentionally arranged textgroups. The article contextualizes the Middle Low German treatises within the tradition of the ›Speculum artis bene moriendi‹, the ›Bilder Ars‹ and Jean Gersons ›Opus tripartitum‹. It reconstructs how the interplay of didactic and performative texts creates a sense of danger in the face of death while simultaneously providing strategies for securing salvation."],["dc.identifier.doi","10.1515/bgsl-2018-0004"],["dc.identifier.eissn","1865-9373"],["dc.identifier.issn","0005-8076"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77883"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","De Gruyter"],["dc.relation.eissn","1865-9373"],["dc.relation.issn","0005-8076"],["dc.title","Gefahrensinn um 1500"],["dc.title.alternative","Das Ars moriendi‑Programm der Handschrift Hamburg, SUB, cod. conv. 12"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Physics. Conference Series"],["dc.bibliographiccitation.volume","2374"],["dc.contributor.affiliation","Bäni, L;"],["dc.contributor.affiliation","Artuso, M;"],["dc.contributor.affiliation","Bachmair, F;"],["dc.contributor.affiliation","Bartosik, M;"],["dc.contributor.affiliation","Beck, H;"],["dc.contributor.affiliation","Bellini, V;"],["dc.contributor.affiliation","Belyaev, V;"],["dc.contributor.affiliation","Bentele, B;"],["dc.contributor.affiliation","Bergonzo, P;"],["dc.contributor.affiliation","Bes, A;"],["dc.contributor.affiliation","Brom, J-M;"],["dc.contributor.affiliation","Chiodini, G;"],["dc.contributor.affiliation","Chren, D;"],["dc.contributor.affiliation","Cindro, V;"],["dc.contributor.affiliation","Claus, G;"],["dc.contributor.affiliation","Collot, J;"],["dc.contributor.affiliation","Cumalat, J;"],["dc.contributor.affiliation","Curtoni, S;"],["dc.contributor.affiliation","Dabrowski, A;"],["dc.contributor.affiliation","D’Alessandro, R;"],["dc.contributor.affiliation","Dauvergne, D;"],["dc.contributor.affiliation","de Boer, W;"],["dc.contributor.affiliation","Dorfer, C;"],["dc.contributor.affiliation","Dünser, M;"],["dc.contributor.affiliation","Eigen, G;"],["dc.contributor.affiliation","Eremin, V;"],["dc.contributor.affiliation","Forneris, J;"],["dc.contributor.affiliation","Gallin-Martel, L;"],["dc.contributor.affiliation","Gallin-Martel, M-L;"],["dc.contributor.affiliation","Gan, K K;"],["dc.contributor.affiliation","Gastal, M;"],["dc.contributor.affiliation","Ghimouz, A;"],["dc.contributor.affiliation","Goffe, M;"],["dc.contributor.affiliation","Goldstein, J;"],["dc.contributor.affiliation","Golubev, A;"],["dc.contributor.affiliation","Gorišek, A;"],["dc.contributor.affiliation","Grigoriev, E;"],["dc.contributor.affiliation","Grosse-Knetter, J;"],["dc.contributor.affiliation","Grummer, A;"],["dc.contributor.affiliation","Hiti, B;"],["dc.contributor.affiliation","Hits, D;"],["dc.contributor.affiliation","Hoeferkamp, M;"],["dc.contributor.affiliation","Hofmann, T;"],["dc.contributor.affiliation","Hosselet, J;"],["dc.contributor.affiliation","Hügging, F;"],["dc.contributor.affiliation","Hutson, C;"],["dc.contributor.affiliation","Jackman, R;"],["dc.contributor.affiliation","Janssen, J;"],["dc.contributor.affiliation","Jennings-Moors, R;"],["dc.contributor.affiliation","Kagan, H;"],["dc.contributor.affiliation","Kanxheri, K;"],["dc.contributor.affiliation","Kis, M;"],["dc.contributor.affiliation","Kramberger, G;"],["dc.contributor.affiliation","Kuleshov, S;"],["dc.contributor.affiliation","Lacoste, A;"],["dc.contributor.affiliation","Lagomarsino, S;"],["dc.contributor.affiliation","Giudice, A Lo;"],["dc.contributor.affiliation","Paz, I López;"],["dc.contributor.affiliation","Lukosi, E;"],["dc.contributor.affiliation","Maazouzi, C;"],["dc.contributor.affiliation","Mandić, I;"],["dc.contributor.affiliation","Marcatili, S;"],["dc.contributor.affiliation","Marino, A;"],["dc.contributor.affiliation","Mathieu, C;"],["dc.contributor.affiliation","Menichelli, M;"],["dc.contributor.affiliation","Mikuž, M;"],["dc.contributor.affiliation","Morozzi, A;"],["dc.contributor.affiliation","Moscatelli, F;"],["dc.contributor.affiliation","Moss, J;"],["dc.contributor.affiliation","Mountain, R;"],["dc.contributor.affiliation","Oh, A;"],["dc.contributor.affiliation","Olivero, P;"],["dc.contributor.affiliation","Pakpour-Tabrizi, A;"],["dc.contributor.affiliation","Passeri, D;"],["dc.contributor.affiliation","Pernegger, H;"],["dc.contributor.affiliation","Perrino, R;"],["dc.contributor.affiliation","Picollo, F;"],["dc.contributor.affiliation","Pomorski, M;"],["dc.contributor.affiliation","Porter, A;"],["dc.contributor.affiliation","Potenza, R;"],["dc.contributor.affiliation","Quadt, A;"],["dc.contributor.affiliation","Rarbi, F;"],["dc.contributor.affiliation","Re, A;"],["dc.contributor.affiliation","Reichmann, M;"],["dc.contributor.affiliation","Roe, S;"],["dc.contributor.affiliation","Rossetto, O;"],["dc.contributor.affiliation","Becerra, D A Sanz;"],["dc.contributor.affiliation","Schmidt, C;"],["dc.contributor.affiliation","Schnetzer, S;"],["dc.contributor.affiliation","Sciortino, S;"],["dc.contributor.affiliation","Scorzoni, A;"],["dc.contributor.affiliation","Seidel, S;"],["dc.contributor.affiliation","Servoli, L;"],["dc.contributor.affiliation","Smith, D S;"],["dc.contributor.affiliation","Sopko, B;"],["dc.contributor.affiliation","Sopko, V;"],["dc.contributor.affiliation","Spagnolo, S;"],["dc.contributor.affiliation","Spanier, S;"],["dc.contributor.affiliation","Stenson, K;"],["dc.contributor.affiliation","Stone, R;"],["dc.contributor.affiliation","Stugu, B;"],["dc.contributor.affiliation","Sutera, C;"],["dc.contributor.affiliation","Traeger, M;"],["dc.contributor.affiliation","Trischuk, W;"],["dc.contributor.affiliation","Truccato, M;"],["dc.contributor.affiliation","Tuvê, C;"],["dc.contributor.affiliation","Velthuis, J;"],["dc.contributor.affiliation","Wagner, S;"],["dc.contributor.affiliation","Wallny, R;"],["dc.contributor.affiliation","Wang, J C;"],["dc.contributor.affiliation","Welch, J;"],["dc.contributor.affiliation","Wermes, N;"],["dc.contributor.affiliation","Wickramasinghe, J;"],["dc.contributor.affiliation","Yamouni, M;"],["dc.contributor.affiliation","Zalieckas, J;"],["dc.contributor.affiliation","Zavrtanik, M;"],["dc.contributor.author","Bäni, L."],["dc.contributor.author","Artuso, M."],["dc.contributor.author","Bachmair, F."],["dc.contributor.author","Bartosik, M."],["dc.contributor.author","Beck, H."],["dc.contributor.author","Bellini, V."],["dc.contributor.author","Belyaev, V."],["dc.contributor.author","Bentele, B."],["dc.contributor.author","Bergonzo, P."],["dc.contributor.author","Bes, A."],["dc.contributor.author","Brom, J.-M."],["dc.contributor.author","Chiodini, G."],["dc.contributor.author","Chren, D."],["dc.contributor.author","Cindro, V."],["dc.contributor.author","Claus, G."],["dc.contributor.author","Collot, J."],["dc.contributor.author","Cumalat, J."],["dc.contributor.author","Curtoni, S."],["dc.contributor.author","Dabrowski, A."],["dc.contributor.author","D’Alessandro, R."],["dc.contributor.author","Dauvergne, D."],["dc.contributor.author","de Boer, W."],["dc.contributor.author","Dorfer, C."],["dc.contributor.author","Dünser, M."],["dc.contributor.author","Eigen, G."],["dc.contributor.author","Eremin, V."],["dc.contributor.author","Forneris, J."],["dc.contributor.author","Gallin-Martel, L."],["dc.contributor.author","Gallin-Martel, M.-L."],["dc.contributor.author","Gan, K. K."],["dc.contributor.author","Gastal, M."],["dc.contributor.author","Ghimouz, A."],["dc.contributor.author","Goffe, M."],["dc.contributor.author","Goldstein, J."],["dc.contributor.author","Golubev, A."],["dc.contributor.author","Gorišek, A."],["dc.contributor.author","Grigoriev, E."],["dc.contributor.author","Grosse-Knetter, J."],["dc.contributor.author","Grummer, A."],["dc.contributor.author","Hiti, B."],["dc.contributor.author","Hits, D."],["dc.contributor.author","Hoeferkamp, M."],["dc.contributor.author","Hofmann, T."],["dc.contributor.author","Hosselet, J."],["dc.contributor.author","Hügging, F."],["dc.contributor.author","Hutson, C."],["dc.contributor.author","Jackman, R."],["dc.contributor.author","Janssen, J."],["dc.contributor.author","Jennings-Moors, R."],["dc.contributor.author","Kagan, H."],["dc.contributor.author","Kanxheri, K."],["dc.contributor.author","Kis, M."],["dc.contributor.author","Kramberger, G."],["dc.contributor.author","Kuleshov, S."],["dc.contributor.author","Lacoste, A."],["dc.contributor.author","Lagomarsino, S."],["dc.contributor.author","Giudice, A. Lo"],["dc.contributor.author","Paz, I. López"],["dc.contributor.author","Lukosi, E."],["dc.contributor.author","Maazouzi, C."],["dc.contributor.author","Mandić, I."],["dc.contributor.author","Marcatili, S."],["dc.contributor.author","Marino, A."],["dc.contributor.author","Mathieu, C."],["dc.contributor.author","Menichelli, M."],["dc.contributor.author","Mikuž, M."],["dc.contributor.author","Morozzi, A."],["dc.contributor.author","Moscatelli, F."],["dc.contributor.author","Moss, J."],["dc.contributor.author","Mountain, R."],["dc.contributor.author","Oh, A."],["dc.contributor.author","Olivero, P."],["dc.contributor.author","Pakpour-Tabrizi, A."],["dc.contributor.author","Passeri, D."],["dc.contributor.author","Pernegger, H."],["dc.contributor.author","Perrino, R."],["dc.contributor.author","Picollo, F."],["dc.contributor.author","Pomorski, M."],["dc.contributor.author","Porter, A."],["dc.contributor.author","Potenza, R."],["dc.contributor.author","Quadt, A."],["dc.contributor.author","Rarbi, F."],["dc.contributor.author","Re, A."],["dc.contributor.author","Reichmann, M."],["dc.contributor.author","Roe, S."],["dc.contributor.author","Rossetto, O."],["dc.contributor.author","Becerra, D. A. Sanz"],["dc.contributor.author","Schmidt, C."],["dc.contributor.author","Schnetzer, S."],["dc.contributor.author","Sciortino, S."],["dc.contributor.author","Scorzoni, A."],["dc.contributor.author","Seidel, S."],["dc.contributor.author","Servoli, L."],["dc.contributor.author","Smith, D. S."],["dc.contributor.author","Sopko, B."],["dc.contributor.author","Sopko, V."],["dc.contributor.author","Spagnolo, S."],["dc.contributor.author","Spanier, S."],["dc.contributor.author","Stenson, K."],["dc.contributor.author","Stone, R."],["dc.contributor.author","Stugu, B."],["dc.contributor.author","Sutera, C."],["dc.contributor.author","Traeger, M."],["dc.contributor.author","Trischuk, W."],["dc.contributor.author","Truccato, M."],["dc.contributor.author","Tuvê, C."],["dc.contributor.author","Velthuis, J."],["dc.contributor.author","Wagner, S."],["dc.contributor.author","Wallny, R."],["dc.contributor.author","Wang, J. C."],["dc.contributor.author","Welch, J."],["dc.contributor.author","Wermes, N."],["dc.contributor.author","Wickramasinghe, J."],["dc.contributor.author","Yamouni, M."],["dc.contributor.author","Zalieckas, J."],["dc.contributor.author","Zavrtanik, M."],["dc.date.accessioned","2022-12-09T09:09:57Z"],["dc.date.available","2022-12-09T09:09:57Z"],["dc.date.issued","2022"],["dc.date.updated","2022-12-09T04:21:29Z"],["dc.description.abstract","Diamond is used as detector material in high energy physics experiments due to its inherent radiation tolerance. The RD42 collaboration has measured the radiation tolerance of chemical vapour deposition (CVD) diamond against proton, pion, and neutron irradiation. Results of this study are summarized in this article. The radiation tolerance of diamond detectors can be further enhanced by using a 3D electrode geometry. We present preliminary results of a poly-crystalline CVD (pCVD) diamond detector with a 3D electrode geometry after irradiation and compare to planar devices of roughly the same thickness."],["dc.identifier.doi","10.1088/1742-6596/2374/1/012172"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118491"],["dc.language.iso","en"],["dc.relation.eissn","1742-6596"],["dc.relation.issn","1742-6588"],["dc.rights.uri","http://creativecommons.org/licenses/by/3.0/"],["dc.title","Radiation tolerance of diamond detectors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Nature Communications"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Llorens, Franc"],["dc.contributor.author","Hermann, Peter"],["dc.contributor.author","Villar-Piqué, Anna"],["dc.contributor.author","Diaz-Lucena, Daniela"],["dc.contributor.author","Nägga, Katarina"],["dc.contributor.author","Hansson, Oskar"],["dc.contributor.author","Santana, Isabel"],["dc.contributor.author","Schmitz, Matthias"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Varges, Daniela"],["dc.contributor.author","Goebel, Stefan"],["dc.contributor.author","Dumurgier, Julien"],["dc.contributor.author","Zetterberg, Henrik"],["dc.contributor.author","Blennow, Kaj"],["dc.contributor.author","Paquet, Claire"],["dc.contributor.author","Baldeiras, Inês"],["dc.contributor.author","Ferrer, Isidro"],["dc.contributor.author","Zerr, Inga"],["dc.date.accessioned","2021-04-14T08:27:37Z"],["dc.date.available","2021-04-14T08:27:37Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41467-020-14373-2"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17201"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82349"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","2041-1723"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","9"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Alzheimer's Research & Therapy"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Hermann, Peter"],["dc.contributor.author","Villar-Piqué, Anna"],["dc.contributor.author","Schmitz, Matthias"],["dc.contributor.author","Schmidt, Christian"],["dc.contributor.author","Varges, Daniela"],["dc.contributor.author","Goebel, Stefan"],["dc.contributor.author","Bunck, Timothy"],["dc.contributor.author","Lindemann, Hanna"],["dc.contributor.author","Bogner, Carla"],["dc.contributor.author","Santana, Isabel"],["dc.contributor.author","Baldeiras, Inês"],["dc.contributor.author","Riggert, Joachim"],["dc.contributor.author","Zerr, Inga"],["dc.contributor.author","Llorens, Franc"],["dc.date.accessioned","2022-02-01T10:31:33Z"],["dc.date.accessioned","2022-08-18T12:39:24Z"],["dc.date.available","2022-02-01T10:31:33Z"],["dc.date.available","2022-08-18T12:39:24Z"],["dc.date.issued","2022-01-13"],["dc.date.updated","2022-07-29T12:17:51Z"],["dc.description.abstract","Background Lipocalin-2 is a glycoprotein that is involved in various physiological and pathophysiological processes. In the brain, it is expressed in response to vascular and other brain injury, as well as in Alzheimer’s disease in reactive microglia and astrocytes. Plasma Lipocalin-2 has been proposed as a biomarker for Alzheimer’s disease but available data is scarce and inconsistent. Thus, we evaluated plasma Lipocalin-2 in the context of Alzheimer’s disease, differential diagnoses, other biomarkers, and clinical data. Methods For this two-center case-control study, we analyzed Lipocalin-2 concentrations in plasma samples from a cohort of n  = 407 individuals. The diagnostic groups comprised Alzheimer’s disease ( n  = 74), vascular dementia ( n  = 28), other important differential diagnoses ( n  = 221), and healthy controls ( n  = 84). Main results were validated in an independent cohort with patients with Alzheimer’s disease ( n  = 19), mild cognitive impairment ( n  = 27), and healthy individuals ( n  = 28). Results Plasma Lipocalin-2 was significantly lower in Alzheimer’s disease compared to healthy controls ( p  < 0.001) and all other groups ( p  < 0.01) except for mixed dementia (vascular and Alzheimer’s pathologic changes). Areas under the curve from receiver operation characteristics for the discrimination of Alzheimer’s disease and healthy controls were 0.783 (95%CI: 0.712–0.855) in the study cohort and 0.766 (95%CI: 0.627–0.905) in the validation cohort. The area under the curve for Alzheimer’s disease versus vascular dementia was 0.778 (95%CI: 0.667–0.890) in the study cohort. In Alzheimer’s disease patients, plasma Lipocalin2 did not show significant correlation with cerebrospinal fluid biomarkers of neurodegeneration and AD-related pathology (total-tau, phosphorylated tau protein, and beta-amyloid 1-42), cognitive status (Mini Mental Status Examination scores), APOE genotype, or presence of white matter hyperintensities. Interestingly, Lipocalin 2 was lower in patients with rapid disease course compared to patients with non-rapidly progressive Alzheimer’s disease ( p  = 0.013). Conclusions Plasma Lipocalin-2 has potential as a diagnostic biomarker for Alzheimer’s disease and seems to be independent from currently employed biomarkers."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.citation","Alzheimer's Research & Therapy. 2022 Jan 13;14(1):9"],["dc.identifier.doi","10.1186/s13195-021-00955-9"],["dc.identifier.pii","955"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98886"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112969"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.publisher","BioMed Central"],["dc.relation.eissn","1758-9193"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject","Dementia"],["dc.subject","Alzheimer’s disease"],["dc.subject","Biomarker"],["dc.subject","Plasma"],["dc.subject","Lipocalin 2"],["dc.subject","Neutrophil gelatinase-associated Lipocalin"],["dc.title","Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]