Belz, Michael

[["dc.bibliographiccitation.firstpage","809"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","European Archives of Psychiatry and Clinical Neuroscience"],["dc.bibliographiccitation.lastpage","817"],["dc.bibliographiccitation.volume","268"],["dc.contributor.author","Krech, Lisa"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Besse, Matthias"],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Wedekind, D."],["dc.contributor.author","Zilles, David"],["dc.date.accessioned","2019-02-26T10:15:46Z"],["dc.date.available","2019-02-26T10:15:46Z"],["dc.date.issued","2018"],["dc.description.abstract","Electroconvulsive therapy (ECT) is the most effective therapy for severe depressive disorders. Though there are known clinical predictors of response (e.g., higher age, presence of psychotic symptoms), there is a lack of knowledge concerning the impact of patients' expectations on treatment outcome and tolerability in terms of possible placebo/nocebo effects. In 31 patients with unipolar or bipolar depressive disorder, we used a questionnaire to investigate the patients' expectations of ECT effectiveness and tolerability prior to and in the course of the treatment. Additionally, the questionnaire was used after the ECT course for a final assessment. Depressive symptoms and putative side-effects were measured at each time point. General linear models were used to analyze the course of depressive symptoms and patients' expectation of ECT effectiveness and tolerability. ECT significantly reduced depressive symptoms with large effect sizes. Patients' rating of ECT effectiveness decreased in parallel: While responders' rating of ECT effectiveness remained stable on a high level, non-responders' rating decreased significantly. Group difference was significant after, but not prior to and during the treatment. Regarding tolerability, there was a (temporary) significant increase in the severity of self-rated symptoms such as headache and memory impairment. In contrast, patients' expectation and assessment of ECT tolerability remained unchanged, and their expectations prior to ECT had no impact on the occurrence of side-effects. These findings contradict the presence of relevant placebo/nocebo effects in the context of ECT when investigating a population of mostly chronic or treatment resistant patients with moderate to severe depressive disorder."],["dc.identifier.doi","10.1007/s00406-017-0840-8"],["dc.identifier.eissn","1433-8491"],["dc.identifier.pmid","28940099"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57612"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Influence of depressed patients' expectations prior to electroconvulsive therapy on its effectiveness and tolerability (Exp-ECT): a prospective study"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Acta Psychiatrica Scandinavica"],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Besse, Matthias"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Zilles‐Wegner, David"],["dc.date.accessioned","2021-06-01T09:41:59Z"],["dc.date.available","2021-06-01T09:41:59Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1111/acps.13314"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85102"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1600-0447"],["dc.relation.issn","0001-690X"],["dc.title","Effectiveness of maintenance electroconvulsive therapy—Evidence from modifications due to the COVID‐19 pandemic"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","148"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","The World Journal of Biological Psychiatry"],["dc.bibliographiccitation.lastpage","154"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Besse, Matthias"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Folsche, Thorsten"],["dc.contributor.author","Vogelgsang, Jonathan"],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Steinacker, Petra"],["dc.contributor.author","Otto, Markus"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Zilles, David"],["dc.date.accessioned","2020-12-10T18:15:21Z"],["dc.date.available","2020-12-10T18:15:21Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1080/15622975.2019.1702717"],["dc.identifier.eissn","1814-1412"],["dc.identifier.issn","1562-2975"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74814"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Serum neurofilament light chain (NFL) remains unchanged during electroconvulsive therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S183"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","S184"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Zilles, David"],["dc.contributor.author","Besse, Matthias"],["dc.contributor.author","Folsche, T."],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Vogelgsang, Jonathan"],["dc.contributor.author","Wiltfang, Jens"],["dc.date.accessioned","2020-04-02T14:45:26Z"],["dc.date.available","2020-04-02T14:45:26Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.euroneuro.2019.09.281"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/63562"],["dc.relation.issn","0924-977X"],["dc.title","P.239 Electroconvulsive therapy and the brain: no increase of neurofilament light chain in the treatment course"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","71"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Der Nervenarzt"],["dc.bibliographiccitation.lastpage","72"],["dc.bibliographiccitation.volume","90"],["dc.contributor.author","Belz, M."],["dc.contributor.author","Besse, M."],["dc.contributor.author","Krech, L."],["dc.contributor.author","Methfessel, I."],["dc.contributor.author","Zilles, D."],["dc.date.accessioned","2020-12-10T14:08:37Z"],["dc.date.available","2020-12-10T14:08:37Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s00115-018-0631-0"],["dc.identifier.eissn","1433-0407"],["dc.identifier.issn","0028-2804"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70499"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.iserratumof","/handle/2/70498"],["dc.title","Erratum zu: Wirksamkeit und Verträglichkeit der Elektrokonvulsionstherapie"],["dc.title.alternative","Erratum to: Effectiveness and tolerability of electroconvulsive therapy. Influence of clinical response from the patient’s point of view"],["dc.title.subtitle","Einfluss des klinischen Ansprechens aus Patientensicht"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","erratum_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","263"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Archives of Psychiatry and Clinical Neuroscience"],["dc.bibliographiccitation.lastpage","269"],["dc.bibliographiccitation.volume","270"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Spang, Miriam"],["dc.contributor.author","Besse, Matthias"],["dc.contributor.author","Folsche, Thorsten"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Zilles, David"],["dc.date.accessioned","2020-12-10T14:10:31Z"],["dc.date.available","2020-12-10T14:10:31Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s00406-019-01046-5"],["dc.identifier.eissn","1433-8491"],["dc.identifier.issn","0940-1334"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70787"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Overlooking the obvious? Influence of electrolyte concentrations on seizure quality parameters in electroconvulsive therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Der Nervenarzt"],["dc.contributor.author","Methfessel, Isabel"],["dc.contributor.author","Belz, Michael"],["dc.contributor.author","Bühler, Fabienne"],["dc.contributor.author","Zilles-Wegner, David"],["dc.date.accessioned","2022-09-01T09:51:24Z"],["dc.date.available","2022-09-01T09:51:24Z"],["dc.date.issued","2022"],["dc.description.abstract","Zusammenfassung\n \n Hintergrund\n Die Anwendungshäufigkeit der Elektrokonvulsionstherapie (EKT) in Deutschland variiert stark in Abhängigkeit von der regionalen Verfügbarkeit. Teilweise wird dieses Versorgungsdefizit durch Zuweisungen an EKT-durchführende Kliniken kompensiert, was jedoch durch dort verfügbare Ressourcen limitiert ist.\n \n \n Ziel der Arbeit\n Untersuchung der externen Zuweisungen zur EKT am Beispiel der Universitätsmedizin Göttingen. Analysiert werden sollen die Zuweiserstruktur, die Patientencharakteristika, die leitliniengerechte Pharmakotherapie vor Indikationsstellung zur EKT sowie das Therapieoutcome im Falle einer Behandlung mit EKT.\n \n \n Material und Methoden\n Externe Anmeldungen zur EKT wurden über ein Jahr systematisch erfasst und retrospektiv ausgewertet. Neben der deskriptiven Darstellung der Daten erfolgte der Abgleich pharmakologischer Vorbehandlungen mit den aktuellen Leitlinienempfehlungen. Das Therapieoutcome nach durchgeführter EKT wurde mittels des klinischen Gesamteindrucks (CGI-I) bestimmt.\n \n \n Ergebnisse\n \n Für\n N\n  = 52 Patienten erfolgte die Anfrage zur Übernahme, davon kamen 82,7 % aus dem stationären Setting und aus einer Entfernung von bis zu 300 km. Unipolare Depressionen (57,7 %) und Störungen aus dem Schizophreniespektrum (36,5 %) waren die häufigsten Diagnosen. Vor Zuweisung erfolgte in der Mehrheit der Fälle mindestens eine leitliniengerechte Vorbehandlung. Bei 18 Patienten wurde eine EKT in unserem Haus durchgeführt, von diesen zeigten 72,7 % ein gutes bis sehr gutes Ansprechen.\n \n \n \n Diskussion\n Anzahl und Radius der Zuweisungen zeigen einen hohen ungedeckten Bedarf in der Versorgung mit EKT und damit einen eingeschränkten Zugang zu einer evidenzbasierten und leitlinienempfohlenen Therapie. Im Sinne einer heimatnahen Behandlung ist anzustreben, EKT als Therapieangebot an mehr Kliniken zu etablieren. Auch bei externen Zuweisungen und damit verbundenen, zum Teil erheblichen Verzögerungen ist die Ansprechrate diagnoseübergreifend gut."],["dc.description.abstract","Abstract\n \n Background\n The application of ECT in Germany varies widely depending on regional availability. This shortfall in ECT supply is partly compensated via referrals to hospitals with ECT services, yet restricted by limited resources in these clinics.\n \n \n Objective\n External referrals for ECT were investigated at the University Medical Center Göttingen. We analyzed the referring institutions, patient characteristics, pharmacotherapy according to current guidelines before indications for ECT, and clinical outcome in cases of treatment with ECT.\n \n \n Material and methods\n All external referrals were systematically recorded and retrospectively evaluated for the time span of 1 year. Besides descriptive presentation of the data, pharmacological pretreatment was compared with the current guideline recommendations. We used overall clinical impression (CGI-I) to determine the treatment response post-ECT.\n \n \n Results\n \n External referrals were made for\n N\n  = 52 patients, 82.7% of whom were from the inpatient setting and from a distance of up to 300 km. The most common diagnoses were unipolar depression (57.7%), followed by schizophrenia spectrum (36.5%). Prior to referral, at least one guideline-based pretreatment was given in the majority of cases. ECT was performed in 18 patients in our hospital, of whom 72.7% showed a good to very good response.\n \n \n \n Conclusion\n Both numbers and radius of external referrals indicate a high unmet need for ECT and thus limited access to this evidence-based and guideline-recommended therapy. As treatment close to home should be the goal, more hospitals are needed to establish (or expand) ECT services; however, even with considerable delays which are often associated with external referrals, the response rate is good across all diagnoses."],["dc.identifier.doi","10.1007/s00115-022-01360-9"],["dc.identifier.pii","1360"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113954"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1433-0407"],["dc.relation.issn","0028-2804"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Versorgungsaspekte der Elektrokonvulsionstherapie: Analyse der externen Zuweisungen an ein universitäres Zentrum"],["dc.title.translated","Health service aspects of electroconvulsive therapy: analysis of external referrals to a university medical center"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]