Ammon, Jan

[["dc.bibliographiccitation.firstpage","994"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Orthopaedic Surgery"],["dc.bibliographiccitation.lastpage","1002"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Saul, Dominik"],["dc.contributor.author","Riekenberg, Juliane"],["dc.contributor.author","Ammon, Jan C."],["dc.contributor.author","Hoffmann, Daniel B."],["dc.contributor.author","Sehmisch, Stephan"],["dc.date.accessioned","2020-06-08T13:10:10Z"],["dc.date.available","2020-06-08T13:10:10Z"],["dc.date.issued","2019"],["dc.description.abstract","Objective Investigation of the treatment of femur fractures and the type of femur fracture‐associated complications regarding timing of surgery and length of hospital stay. Methods In this retrospective cohort study, a total of 358 hip fractures were evaluated retrospectively from 1 January 2008 until 31 December 2010 at a level I trauma center in Germany. Inclusion criteria was age >18 years and a proximal femur fracture. Both sexes were evaluated. Mean age was 75.5 years, most patients were female (63.7%). Intervention was the operative treatment of proximal femur fracture. Outcome parameters were time until surgery, complications, reoperations, mortality, and length of hospital stay. Results Among the proximal femur fractures (n = 358), 46.6% were pertrochanteric, 11.2% subtrochanteric, and 42.2% femoral neck fractures. Operation upon hip fractures was managed regularly within 24 hours of injury (73%; mean for femoral neck: 28.3 hrs.; mean for pertrochanteric fractures: 21.4 hrs.; mean for subtrochanteric fractures: 19.5 hrs.). Delayed treatment, as well as implantation of hip total endoprosthesis (TEP), increased the overall length of hospital stay (15.4 vs 17.6 days; 18.1 vs 15.8 days). Accordingly, surgical procedures performed within 24 hours of injury resulted in a shorter hospital residence. Longest delay of operation was measured for hip fractures (28.3 hrs.). In 351 patients, secondary injuries were detected in 94 individuals (26%), with fractures being the most common secondary injury (n = 40). We recorded postoperative complications of nonsurgical and surgical origin, and 33.6% of our patient cohort displayed complications. Complications were distributed among 118 patients. There was no significant difference in complications regarding the time of operation, with most nonsurgical and surgical complications appearing within 24 hours after operation (n = 110 vs n = 31). Nonsurgical complications, such as anemia (n = 49) and electrolyte imbalances (n = 30), were observed more frequently than surgical complications (n = 107 vs n = 34); however, these complications were reduced by delay in surgery (82.0% in 6–24 hrs. vs 74.2% in ≥24 hrs.). Anticoagulant therapy and age did not affect postoperative complications. The hospital mortality of patients was 6.2%. Follow‐up was restrained to ambulatory visits in the clinic. Conclusions Surgical management of hip fractures performed within 24 hours of injury minimizes hospital stay. We did not detect significant differences in the spectrum or number of complications regarding delay of surgery. Surgical complications mainly occur with rapid primary care, and medical complications can be reduced by more intensive preparation of patient and operation procedures."],["dc.identifier.doi","10.1111/os.12524"],["dc.identifier.isi","WOS:000488199600001"],["dc.identifier.pmid","31568676"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16519"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66198"],["dc.identifier.url","https://publons.com/publon/28102254/"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","John Wiley \\u0026 Sons Australia, Ltd"],["dc.relation.eissn","1757-7861"],["dc.relation.issn","1757-7853"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Hip Fractures: Therapy, Timing, and Complication Spectrum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","509"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Calcified Tissue International"],["dc.bibliographiccitation.lastpage","520"],["dc.bibliographiccitation.volume","92"],["dc.contributor.author","Komrakova, Marina"],["dc.contributor.author","Sehmisch, Stephan"],["dc.contributor.author","Tezval, Mohammad"],["dc.contributor.author","Ammon, Jan"],["dc.contributor.author","Lieberwirth, Peggy"],["dc.contributor.author","Sauerhoff, Cordula"],["dc.contributor.author","Trautmann, Lukas"],["dc.contributor.author","Wicke, Michael"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Stuermer, Klaus-Michael"],["dc.contributor.author","Stuermer, Ewa Klara"],["dc.date.accessioned","2018-11-07T09:24:23Z"],["dc.date.available","2018-11-07T09:24:23Z"],["dc.date.issued","2013"],["dc.description.abstract","Numerous whole-body vibration (WBV) devices of various forces are available on the market, although their influence on the musculoskeletal system is not yet understood. The effect of different WBVs on bone healing and muscle function was evaluated in rats ovariectomized at 3 months of age. 2 months after ovariectomy, bilateral metaphyseal tibia osteotomy and T-plate osteosynthesis were performed. Rats were divided into groups: intact, OVX, and OVX exposed to vertical WBVs of 35, 50, 70, or 90 Hz (experiment 1) or horizontal WBVs of 30, 50, 70, or 90 Hz (experiment 2) 5 days after osteotomy (0.5 mm, 15 min/day for 30 days). The tibia and gastrocnemius and soleus muscles were collected. Vertical vibrations (> 35 Hz) improved cortical and callus densities, enlarged callus area and width, suppressed the tartrate-resistant acid phosphatase gene, enhanced citrate synthase activity, accelerated osteotomy bridging (35 and 50 Hz), upregulated the osteocalcin (Oc) gene (70 Hz), and increased relative muscle weight (50 Hz). Horizontal vibrations reduced cortical width (< 90 Hz) and callus density (30 Hz), enhanced alkaline phosphatase (Alp) gene expression (50 Hz), decreased the size of oxidative fibers (35 and 70 Hz), and increased capillary density (70, 90 Hz). Biomechanical data; serum Oc, Alp, and creatine kinase activities; body weight; and food intake did not change after WBVs. Vertical WBVs of 35 and 50 Hz produced more favorable results than the higher frequencies. Horizontal WBV showed no positive or negative effects. Further studies are needed to elucidate the effects of WBV on different physiological systems, and precautions must be taken when implementing WBV in the treatment of patients."],["dc.description.sponsorship","German Research Foundation (DFG) [STU 478/3-2]"],["dc.identifier.doi","10.1007/s00223-013-9706-x"],["dc.identifier.isi","000319021400003"],["dc.identifier.pmid","23416966"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10285"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29810"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0171-967X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Identification of a Vibration Regime Favorable for Bone Healing and Muscle in Estrogen-Deficient Rats"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]