Dullin, Christian

[["dc.bibliographiccitation.artnumber","365401"],["dc.bibliographiccitation.issue","36"],["dc.bibliographiccitation.journal","Journal of Physics D Applied Physics"],["dc.bibliographiccitation.volume","47"],["dc.contributor.author","Gureyev, Timur"],["dc.contributor.author","Mayo, S. C."],["dc.contributor.author","Nesterets, Ya I."],["dc.contributor.author","Mohammadi, S."],["dc.contributor.author","Lockie, D."],["dc.contributor.author","Menk, R. H."],["dc.contributor.author","Arfelli, F."],["dc.contributor.author","Pavlov, K. M."],["dc.contributor.author","Kitchen, M. J."],["dc.contributor.author","Zanconati, F."],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Tromba, Giuliana"],["dc.date.accessioned","2018-11-07T09:35:19Z"],["dc.date.available","2018-11-07T09:35:19Z"],["dc.date.issued","2014"],["dc.description.abstract","We report the results of a systematic study of phase-contrast x-ray computed tomography in the propagation-based and analyser-based modes using specially designed phantoms and excised breast tissue samples. The study is aimed at the quantitative evaluation and subsequent optimization, with respect to detection of small tumours in breast tissue, of the effects of phase contrast and phase retrieval on key imaging parameters, such as spatial resolution, contrast-to-noise ratio, x-ray dose and a recently proposed 'intrinsic quality' characteristic which combines the image noise with the spatial resolution. We demonstrate that some of the methods evaluated in this work lead to substantial (more than 20-fold) improvement in the contrast-to-noise and intrinsic quality of the reconstructed tomographic images compared with conventional techniques, with the measured characteristics being in good agreement with the corresponding theoretical estimations. This improvement also corresponds to an approximately 400-fold reduction in the x-ray dose, compared with conventional absorption-based tomography, without a loss in the imaging quality. The results of this study confirm and quantify the significant potential benefits achievable in three-dimensional mammography using x-ray phase-contrast imaging and phase-retrieval techniques."],["dc.identifier.doi","10.1088/0022-3727/47/36/365401"],["dc.identifier.isi","000341769900016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32359"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Iop Publishing Ltd"],["dc.relation.issn","1361-6463"],["dc.relation.issn","0022-3727"],["dc.title","Investigation of the imaging quality of synchrotron-based phase-contrast mammographic tomography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2315"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Physics in Medicine and Biology"],["dc.bibliographiccitation.lastpage","2332"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Baran, P."],["dc.contributor.author","Pacile, S."],["dc.contributor.author","Nesterets, Y. I."],["dc.contributor.author","Mayo, S. C."],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Dreossi, D."],["dc.contributor.author","Arfelli, F."],["dc.contributor.author","Thompson, David N."],["dc.contributor.author","Lockie, D."],["dc.contributor.author","McCormack, M. Luke"],["dc.contributor.author","Taba, S. T."],["dc.contributor.author","Brun, F."],["dc.contributor.author","Pinamonti, M."],["dc.contributor.author","Nickson, C."],["dc.contributor.author","Hall, C."],["dc.contributor.author","Dimmock, M."],["dc.contributor.author","Zanconati, F."],["dc.contributor.author","Cholewa, M."],["dc.contributor.author","Quiney, H."],["dc.contributor.author","Brennan, P. C."],["dc.contributor.author","Tromba, Giuliana"],["dc.contributor.author","Gureyev, Timur"],["dc.date.accessioned","2018-11-07T10:26:07Z"],["dc.date.available","2018-11-07T10:26:07Z"],["dc.date.issued","2017"],["dc.description.abstract","The aim of this study was to optimise the experimental protocol and data analysis for in-vivo breast cancer x-ray imaging. Results are presented of the experiment at the SYRMEP beamline of Elettra Synchrotron using the propagation-based phase-contrast mammographic tomography method, which incorporates not only absorption, but also x-ray phase information. In this study the images of breast tissue samples, of a size corresponding to a full human breast, with radiologically acceptable x-ray doses were obtained, and the degree of improvement of the image quality (from the diagnostic point of view) achievable using propagation-based phase-contrast image acquisition protocols with proper incorporation of x-ray phase retrieval into the reconstruction pipeline was investigated. Parameters such as the x-ray energy, sample-to-detector distance and data processing methods were tested, evaluated and optimized with respect to the estimated diagnostic value using a mastectomy sample with a malignant lesion. The results of quantitative evaluation of images were obtained by means of radiological assessment carried out by 13 experienced specialists. A comparative analysis was performed between the x-ray and the histological images of the specimen. The results of the analysis indicate that, within the investigated range of parameters, both the objective image quality characteristics and the subjective radiological scores of propagation-based phase-contrast images of breast tissues monotonically increase with the strength of phase contrast which in turn is directly proportional to the product of the radiation wavelength and the sample-to-detector distance. The outcomes of this study serve to define the practical imaging conditions and the CT reconstruction procedures appropriate for low-dose phase-contrast mammographic imaging of live patients at specially designed synchrotron beamlines."],["dc.identifier.doi","10.1088/1361-6560/aa5d3d"],["dc.identifier.isi","000395886000004"],["dc.identifier.pmid","28140377"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42972"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Iop Publishing Ltd"],["dc.relation.issn","1361-6560"],["dc.relation.issn","0031-9155"],["dc.title","Optimization of propagation-based x-ray phase-contrast tomography for breast cancer imaging"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","3099"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Biomedical Optics Express"],["dc.bibliographiccitation.lastpage","3112"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Pacile, S."],["dc.contributor.author","Brun, F."],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Nesterest, Y. I."],["dc.contributor.author","Dreossi, D."],["dc.contributor.author","Mohammadi, S."],["dc.contributor.author","Tonutti, M."],["dc.contributor.author","Stacul, F."],["dc.contributor.author","Lockie, D."],["dc.contributor.author","Zanconati, F."],["dc.contributor.author","Accardo, A."],["dc.contributor.author","Tromba, Giuliana"],["dc.contributor.author","Gureyev, Timur"],["dc.date.accessioned","2018-11-07T09:53:51Z"],["dc.date.available","2018-11-07T09:53:51Z"],["dc.date.issued","2015"],["dc.description.abstract","Results are presented of a feasibility study of three-dimensional X-ray tomographic mammography utilising in-line phase contrast. Experiments were performed at SYRMEP beamline of Elettra synchrotron. A specially designed plastic phantom and a mastectomy sample containing a malignant lesion were used to study the reconstructed image quality as a function of different image processing operations. Detailed evaluation and optimization of image reconstruction workflows have been carried out using combinations of several advanced computed tomography algorithms with different pre-processing and post-processing steps. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. A number of objective image quality indices have been applied for quantitative evaluation of the results, and these were compared with subjective assessments of the same images by three experienced radiologists and one pathologist. The outcomes of this study provide practical guidelines for the optimization of image processing workflows in synchrotron-based phase-contrast mammo-tomography. (C) 2015 Optical Society of America"],["dc.description.sponsorship","EXTREMA COST Action [MP1207]"],["dc.identifier.doi","10.1364/BOE.6.003099"],["dc.identifier.isi","000359006000032"],["dc.identifier.pmid","26309770"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36418"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Optical Soc Amer"],["dc.relation.issn","2156-7085"],["dc.title","Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","2740"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","2750"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Tavakoli Taba, Seyedamir"],["dc.contributor.author","Baran, Patrycja"],["dc.contributor.author","Nesterets, Yakov I."],["dc.contributor.author","Pacile, Serena"],["dc.contributor.author","Wienbeck, Susanne"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Pavlov, Konstantin"],["dc.contributor.author","Maksimenko, Anton"],["dc.contributor.author","Lockie, Darren"],["dc.contributor.author","Mayo, Sheridan C."],["dc.contributor.author","Quiney, Harry M."],["dc.contributor.author","Dreossi, Diego"],["dc.contributor.author","Arfelli, Fulvia"],["dc.contributor.author","Tromba, Giuliana"],["dc.contributor.author","Lewis, Sarah"],["dc.contributor.author","Gureyev, Timur E."],["dc.contributor.author","Brennan, Patrick C."],["dc.date.accessioned","2020-12-10T14:10:12Z"],["dc.date.available","2020-12-10T14:10:12Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00330-019-06567-0"],["dc.identifier.eissn","1432-1084"],["dc.identifier.issn","0938-7994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70680"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Comparison of propagation-based CT using synchrotron radiation and conventional cone-beam CT for breast imaging"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","784"],["dc.bibliographiccitation.journal","Journal of Synchrotron Radiation"],["dc.bibliographiccitation.lastpage","789"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Mohammadi, Sara"],["dc.contributor.author","Larsson, Emanuel"],["dc.contributor.author","Alves, Frauke"],["dc.contributor.author","Dal Monego, Simeone"],["dc.contributor.author","Biffi, Stefania"],["dc.contributor.author","Garrovo, Chiara"],["dc.contributor.author","Lorenzon, Andrea"],["dc.contributor.author","Tromba, Giuliana"],["dc.contributor.author","Dullin, Christian"],["dc.date.accessioned","2018-11-07T09:38:19Z"],["dc.date.available","2018-11-07T09:38:19Z"],["dc.date.issued","2014"],["dc.description.abstract","Propagation-based X-ray phase-contrast computed tomography (PBI) has already proven its potential in a great variety of soft-tissue-related applications including lung imaging. However, the strong edge enhancement, caused by the phase effects, often hampers image segmentation and therefore the quantitative analysis of data sets. Here, the benefits of applying single-distance phase retrieval prior to the three-dimensional reconstruction (PhR) are discussed and quantified compared with three-dimensional reconstructions of conventional PBI data sets in terms of contrast-to-noise ratio (CNR) and preservation of image features. The PhR data sets show more than a tenfold higher CNR and only minor blurring of the edges when compared with PBI in a predominately absorption-based set-up. Accordingly, phase retrieval increases the sensitivity and provides more functionality in computed tomography imaging."],["dc.identifier.doi","10.1107/S1600577514009333"],["dc.identifier.isi","000338124300019"],["dc.identifier.pmid","24971975"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33044"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1600-5775"],["dc.relation.issn","0909-0495"],["dc.title","Quantitative evaluation of a single-distance phase-retrieval method applied on in-line phase-contrast images of a mouse lung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","2642"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","IEEE Transactions on Medical Imaging"],["dc.bibliographiccitation.lastpage","2650"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Baran, Patrycja"],["dc.contributor.author","Mayo, Sheridan"],["dc.contributor.author","McCormack, Mikkaela"],["dc.contributor.author","Pacile, Serena"],["dc.contributor.author","Tromba, Giuliana"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Zanconati, Fabrizio"],["dc.contributor.author","Arfelli, Fulvia"],["dc.contributor.author","Dreossi, Diego"],["dc.contributor.author","Fox, Jane"],["dc.contributor.author","Prodanovic, Zdenka"],["dc.contributor.author","Cholewa, Marian"],["dc.contributor.author","Quiney, Harry"],["dc.contributor.author","Dimmock, Matthew"],["dc.contributor.author","Nesterets, Yakov"],["dc.contributor.author","Thompson, Darren"],["dc.contributor.author","Brennan, Patrick"],["dc.contributor.author","Gureyev, Timur"],["dc.date.accessioned","2020-12-10T18:26:18Z"],["dc.date.available","2020-12-10T18:26:18Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1109/TMI.2018.2845905"],["dc.identifier.eissn","1558-254X"],["dc.identifier.issn","0278-0062"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76034"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","High-Resolution X-Ray Phase-Contrast 3-D Imaging of Breast Tissue Specimens as a Possible Adjunct to Histopathology"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

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