Hosseini, Ali Seif Amir

[["dc.bibliographiccitation.firstpage","1293"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","1307"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Rücker, Gerta"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Kim, Hyun S."],["dc.contributor.author","Uhlig, Annemarie"],["dc.date.accessioned","2019-08-05T10:33:02Z"],["dc.date.available","2019-08-05T10:33:02Z"],["dc.date.issued","2018"],["dc.description.abstract","Purpose To compare partial nephrectomy (PN), radiofrequency ablation (RFA), cryoablation (CRA) and microwave ablation (MWA) regarding oncologic, perioperative and functional outcomes. Material and methods The MEDLINE, EMBASE and COCHRANE libraries were searched for studies comparing PN, RFA, CRA or MWA and reporting on any-cause or cancer-specific mortality, local recurrence, complications or renal function. Network meta-analyses were performed. Results Forty-seven studies with 24,077 patients were included. Patients receiving RFA, CRA or MWA were older and had more comorbidities compared with PN. All-cause mortality was higher for CRA and RFA compared with PN (incidence rate ratio IRR = 2.58, IRR = 2.58, p < 0.001, respectively). No significant differences in cancer-specific mortality were evident. Local recurrence was higher for CRA, RFA and MWA compared with PN (IRR = 4.13, IRR = 1.79, IRR = 2.52, p < 0.05 respectively). A decline in renal function was less pronounced after RFA versus PN, CRA and MWA (mean difference in GFR MD = 6.49; MD = 5.82; MD = 10.89, p < 0.05 respectively). Conclusion Higher overall survival and local control of PN compared with ablative therapies did not translate into significantly better cancer-specific mortality. Most studies carried a high risk of bias by selecting younger and healthier patients for PN, which may drive superior survival and local control. Physicians should be aware of the lack of high-quality evidence and the potential benefits of ablative techniques for certain patients, including a superior complication profile and renal function preservation. Key Points • Patients selected for ablation of small renal masses are older and have more comorbidities compared with those undergoing partial nephrectomy. • Partial nephrectomy yields lower all-cause mortality, which is probably biased by patient selection and does not translate into prolonged cancer-free survival. • The decline of renal function is smallest after radiofrequency ablation for small renal masses."],["dc.identifier.doi","10.1007/s00330-018-5660-3"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62282"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","0938-7994"],["dc.relation.issn","1432-1084"],["dc.title","Partial nephrectomy versus ablative techniques for small renal masses: a systematic review and network meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","509"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Langenbeck s Archives of Surgery"],["dc.bibliographiccitation.lastpage","519"],["dc.bibliographiccitation.volume","402"],["dc.contributor.author","Dango, Sebastian"],["dc.contributor.author","Beißbarth, Tim"],["dc.contributor.author","Weiss, Elisabeth"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Raddatz, Dirk"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Beham, Alexander Wilhelm"],["dc.date.accessioned","2018-11-07T10:24:29Z"],["dc.date.available","2018-11-07T10:24:29Z"],["dc.date.issued","2017"],["dc.description.abstract","Upper GI bleeding remains one of the most common emergencies with a substantial overall mortality rate of up to 30%. In severe ill patients, death does not occur due to failure of hemostasis, either medical or surgical, but mainly from comorbidities, treatment complications, and decreased tolerated blood loss. Management strategies have changed dramatically over the last two decades and include primarily endoscopic intervention in combination with acid-suppressive therapy and decrease in surgical intervention. Herein, we present one of the largest patient-based analysis assessing clinical parameters and outcome in patients undergoing endoscopy with an upper GI bleeding. Data were further analyzed to identify potential new risk factors and to investigate the role of surgery. In this retrospective study, we aimed to analyze outcome of patients with an UGIB and data were analyzed to identify potential new risk factors and the role of surgery. Data collection included demographic data, laboratory results, endoscopy reports, and details of management including blood administration, and surgery was carried out. Patient events were grouped and defined as \"overall\" events and \"operated,\" \"non-operated,\" and \"operated and death\" as well as \"non-operated and death\" where appropriate. Blatchford, clinical as well as complete Rockall-score analysis, risk stratification, and disease-related mortality rate were calculated for each group for comparison. Overall, 253 patients were eligible for analysis: endoscopy was carried out in 96% of all patients, 17% needed surgical intervention after endoscopic failure of bleeding control due to persistent bleeding, and the remaining 4% of patients were subjected directly to surgery. The median length of stay to discharge was 26 days. Overall mortality was 22%; out of them, almost 5% were operated and died. Anticoagulation was associated with a high in-hospital mortality risk (23%) and was increased once patients were taken to surgery (43%). Patients taking steroids presented with a risk of death of 26%, once taken to surgery the risk increased to 80%. Patients with liver cirrhosis had a risk of death of 42%; we observed a better outcome for these patients once taken to theater. Clinically, once scored with Blatchford score, statistical correlation was found for initial need for blood transfusion and surgical intervention. Clinical as well as complete Rockall score revealed a correlation between need for blood transfusion as well as surgical intervention in addition with a decreased outcome with increasing Rockall scores. Risk factor analysis including comorbidity, drug administration, and anticoagulation therapy introduced the combination of tumor and non-steroidal antirheumatic medication as independent risk factors for increased disease-related mortality. UGIB remains challenging and endoscopy is the first choice of intervention. Care must be taken once a patient is taking antirheumatic non-steroidal pain medication and suffers from cancer. In patients with presence of liver cirrhosis, an earlier surgical intervention may be considered, in particular for patients with recurrent bleeding. Embolization is not widely available and carries the risk of necrosis of the affected organ and should be restricted to a subgroup of patients not primarily eligible for surgery once endoscopy has failed. Taken together, an interdisciplinary approach including gastroenterologists as well as surgeons should be used once the patient is admitted to the hospital to define the best treatment option."],["dc.identifier.doi","10.1007/s00423-017-1552-2"],["dc.identifier.isi","000400365500012"],["dc.identifier.pmid","28091770"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42673"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Springer"],["dc.relation.issn","1435-2451"],["dc.relation.issn","1435-2443"],["dc.title","Relevance of surgery in patients with non-variceal upper gastrointestinal bleeding"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4691"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","4698"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Voit, Dirk"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Sprenger, Thilo"],["dc.contributor.author","Beham, Alexander Wilhelm"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Biggemann, Lorenz"],["dc.date.accessioned","2020-05-13T13:45:02Z"],["dc.date.available","2020-05-13T13:45:02Z"],["dc.date.issued","2019"],["dc.description.abstract","Purpose To assess the diagnostic potential of dynamic real-time MRI for fundoplication failure in patients with persistent or recurrent GERD-like (gastroesophageal reflux disease) complaints. Material and methods Twenty-two consecutive patients (male n = 11; female n = 11; median age 59 years) with recurrent or persistent GERD-like symptom after fundoplication were enrolled between 2015 and 2017. Median duration of GERD-like symptoms was 21 months. Real-time MRI (3 Tesla) was performed at 40 ms temporal resolution using undersampled radial fast low-angle shot acquisitions with nonlinear inverse image reconstruction. MRI movies dynamically visualized bolus transit of pineapple juice through the gastroesophageal junction, position of the fundoplication wrap and recurring hernia or reflux during Valsalva maneuver. MRI results were compared to endoscopic findings. Results Real-time MRI was successfully completed in all patients without adverse events (average examination time 15 min). Morphological correlates for GERD-like symptoms were evident in 20 patients (90.1%) with gastric reflux in 19 cases. Nine patients (40.1%) had wrap disruption and recurrent gastric hernia. Wrap migration or telescoping hernia was detected in nine patients (40.1%). One patient presented with continued reflux despite intact fundoplication wrap. Esophageal dysmotility with delayed bolus passage was observed in one case. On endoscopy, gastric hernia or wrap disruption was diagnosed in seven cases, and esophagitis or Barret’s metaplasia in nine cases."],["dc.identifier.doi","10.1007/s00330-019-06025-x"],["dc.identifier.pmid","30805702"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65369"],["dc.language.iso","en"],["dc.relation.eissn","1432-1084"],["dc.relation.issn","0938-7994"],["dc.title","Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","108856"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Ahmed, Saheeb"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Biggemann, Lorenz"],["dc.date.accessioned","2020-05-13T13:44:06Z"],["dc.date.available","2020-05-13T13:44:06Z"],["dc.date.issued","2020-04"],["dc.description.abstract","Purpose To evaluate the diagnostic potential of real-time MRI for dynamic assessment of gastroesophageal reflux in patients with GERD (gastroesophageal reflux disease)-like symptoms compared to pH-metry and impedance. Methods Patients who underwent real-time MRI and pH-metry between 2015–2018 were included in this retrospective study. Real-time MRI at 3 T was achieved by undersampled radial FLASH acquisitions with iterative image reconstruction by NLINV. Real-time MRI visualized transit of pineapple juice through the gastroesophageal junction and during Valsalva maneuver. MRI results were compared to 24 h pH-metry to assess acidic reflux (following Lyon Consensus guidelines) and to impedance to assess non-acidic reflux. A standard 2 × 2 table was chosen to calculate diagnostic performance. Results 91/93 eligible patients fulfilled inclusion criteria (male n = 49; female n = 42; median age 55 y). All MRI studies were successfully completed without adverse events at a mean examination time of 15 min. On real-time MRI, reflux was evident in 60 patients (66 %). pH-metry revealed reflux in 41 patients (45 %), and impedance in 54 patients (59 %). Compared to pH-metry and impedance, real-time MRI sensitivity was 0.78 (95 % CI: 0.66-0.87), specificity 0.67 (95 % CI: 0.45-0.84) and PPV 0.87 (95 % CI: 0.75-0.94). Conclusion Real-time MRI is an imaging method for assessment of gastroesophageal reflux in patients with GERD-like symptoms. Considering its high positive predictive value, real-time MRI can accurately identify patients in which further invasive testing with pH-metry and impedance might be considered."],["dc.identifier.doi","10.1016/j.ejrad.2020.108856"],["dc.identifier.pmid","32062571"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65362"],["dc.language.iso","en"],["dc.relation.eissn","1872-7727"],["dc.relation.issn","0720-048X"],["dc.title","Real-time MRI for dynamic assessment of gastroesophageal reflux disease: Comparison to pH-metry and impedance"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","Journal of Clinical Oncology"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Slotta, Jan"],["dc.contributor.author","Panahi, Babak"],["dc.contributor.author","Jenzawski, Peter"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Kollmar, Otto"],["dc.contributor.author","Engelke, Christoph"],["dc.date.accessioned","2018-11-07T09:40:06Z"],["dc.date.available","2018-11-07T09:40:06Z"],["dc.date.issued","2014"],["dc.identifier.isi","000358613200535"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33437"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Clinical Oncology"],["dc.publisher.place","Alexandria"],["dc.relation.conference","50th Annual Meeting of the American-Society-of-Clinical-Oncology"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","1527-7755"],["dc.relation.issn","0732-183X"],["dc.title","DEB40 mu m-TACE: Early single-center results in 23 patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","728"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Clinical Imaging"],["dc.bibliographiccitation.lastpage","733"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Schwarz, Alexander"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Spiro, Judith Eva"],["dc.contributor.author","Kertesz, Andras"],["dc.contributor.author","Zwaka, Paul Anton"],["dc.contributor.author","Lotz, Joachim"],["dc.date.accessioned","2018-11-07T09:23:11Z"],["dc.date.available","2018-11-07T09:23:11Z"],["dc.date.issued","2013"],["dc.description.abstract","Purpose: The purpose of the study was to determine the prevalence of fractures and incidental findings (IF) with emphasis on clinical significance. Materials and methods: A total of 784 patients were evaluated by computed tomography. Fractures and IF were registered and classified as significant if they were recommended for additional diagnostics or therapy. Results: Four hundred seventy of 784 patients (60%) sustained a fracture. Significant fractures were found in 694/1213 fractures (57%); nonsignificant fractures were found in 519/1213 (43%) fractures. A total of 972 IF were observed in 464/784 (59%) patients. Significant findings were found in 358/972 findings (37%). There were 1.5 fractures and 1.2 IF per patient. Conclusion: There is a high prevalence of significant fractures (57%) and IF (37%). (c) 2013 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.clinimag.2012.11.002"],["dc.identifier.isi","000321029100019"],["dc.identifier.pmid","23312456"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29522"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0899-7071"],["dc.title","Current perspective of multidetector computed tomography (MDCT) in patients after midface and craniofacial trauma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","69"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Cell Transplantation"],["dc.bibliographiccitation.lastpage","78"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Koenig, Sarah"],["dc.contributor.author","Krause, Petra"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Rave-Fraenk, Margret"],["dc.contributor.author","Kimmina, Sarah"],["dc.contributor.author","Entwistle, Andrew Lee"],["dc.contributor.author","Hermann, Robert Michael"],["dc.contributor.author","Hess, Clemens Friedrich"],["dc.contributor.author","Christiansen, Hans"],["dc.date.accessioned","2021-06-01T10:48:50Z"],["dc.date.available","2021-06-01T10:48:50Z"],["dc.date.issued","2009"],["dc.description.abstract","Near infrared fluorescence (NIRF) optical imaging is a technique particularly powerful when studying in vivo processes at the molecular level in preclinical animal models. We recently demonstrated liver irradiation under the additional stimulus of partial hepatectomy as being an effective primer in the rat liver repopulation model based on hepatocyte transplantation. The purpose of this study was to assess optical imaging and the feasibility of donor cell expansion tracking in vivo using a fluorescent probe. Livers of dipeptidylpeptidase IV (DPPIV)-deficient rats were preconditioned with irradiation. Four days later, a partial hepatectomy was performed and wild-type (DPPIV(+)) hepatocytes were transplanted into recipient livers via the spleen. Repopulation by transplanted DPPIV(+) hepatocytes was detected in vivo with Cy5.5-conjugated DPPIV antibody using the eXplore Optix (TM) System (GE HealthCare). Results were compared with nontransplanted control animals and transplanted animals receiving nonspecific antibody. Optical imaging detected Cy5.5-specific fluorescence in the liver region of the transplanted animals, increasing in intensity with time, representing extensive host liver repopulation within 16 weeks following transplantation. A general pattern of donor cell multiplication emerged, with an initially accelerating growth curve and later plateau phase. In contrast, no specific fluorescence was detected in the control groups. Comparison with ex vivo immunofluorescence staining of liver sections confirmed the optical imaging results. Optical imaging constitutes a potent method of assessing the longitudinal kinetics of liver repopulation in the rat transplantation model. Our results provide a basis for the future development of clinical protocols for suitable fluorescent dyes and imaging technologies."],["dc.identifier.doi","10.3727/096368909788237186"],["dc.identifier.isi","000266055100007"],["dc.identifier.pmid","19476210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86068"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cognizant Communication Corp"],["dc.relation.eissn","1555-3892"],["dc.relation.issn","0963-6897"],["dc.title","Noninvasive Imaging of Liver Repopulation following Hepatocyte Transplantation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","ueg2.12135"],["dc.bibliographiccitation.journal","United European Gastroenterology Journal"],["dc.contributor.author","Kuellmer, Armin"],["dc.contributor.author","Mangold, Tobias"],["dc.contributor.author","Bettinger, Dominik"],["dc.contributor.author","Maruschke, Lars"],["dc.contributor.author","Wannhoff, Andreas"],["dc.contributor.author","Caca, Karel"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Kleemann, Tobias"],["dc.contributor.author","Schulz, Thomas"],["dc.contributor.author","Schmidt, Arthur"],["dc.date.accessioned","2021-10-01T09:58:48Z"],["dc.date.available","2021-10-01T09:58:48Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1002/ueg2.12135"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90148"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.relation.eissn","2050-6414"],["dc.relation.issn","2050-6406"],["dc.title","Over‐the‐scope clip versus transcatheter arterial embolization for refractory peptic ulcer bleeding—A propensity score matched analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","14"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","19"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Beham, Alexander Wilhelm"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Joseph, Arun A."],["dc.contributor.author","Voit, Dirk"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Biggemann, Lorenz"],["dc.date.accessioned","2020-05-13T13:45:25Z"],["dc.date.available","2020-05-13T13:45:25Z"],["dc.date.issued","2018"],["dc.description.abstract","The purpose of this study was to assess the reproducibility of functional and anatomical parameters of swallowing events as determined by real-time MRI at 40 ms temporal resolution (25 frames per second). Twenty-three consecutive patients with gastroesophageal reflux disease (GERD) underwent real-time MRI of the gastroesophageal junction at 3.0 T. Real-time MRI was based on highly undersampled radial fast low angle shot (FLASH) acquisitions with iterative image reconstruction by regularized nonlinear inversion (NLINV). MRI movies visualized the esophageal transport of a pineapple juice bolus, its passage through the gastroesophageal junction and functional responses during a Valsalva maneuver. His-angle, sphincter position, sphincter length and sphincter transit time were assessed by two radiologists. Interobserver and intraobserver intraclass correlation coefficients (ICC) were evaluated and Bland-Altman plots were constructed to assess the observer agreement. Interobserver agreement was excellent for sphincter transit time (ICC = 0.92), His-angle (ICC = 0.93), His-angle during Valsalva maneuver (ICC = 0.91) and sphincter-to-diaphragm distance (ICC = 0.98). Sphincter length and oesophageal diameter showed good interobserver agreement (ICC = 0.62 and ICC = 0.70). Intraobserver agreement was good for sphincter length (ICC = 0.80) and excellent for sphincter transit time, His-angle and His-angle during Valsalva maneuver, sphincter-to-diaphragm distance, and esophageal diameter (ICC = 0.91; ICC = 0.97; ICC = 0.97; ICC = 0.998; ICC = 0.93). All functional parameters of the gastroesophageal junction had good to excellent reproducibility. Visual assessment of Bland Altman plots did not reveal any systematic interobserver bias. In conclusion, the visualization of swallowing events by real-time MRI has a high potential for clinical application in gastroesophageal reflux disease."],["dc.identifier.doi","10.1016/j.ejrad.2018.04.029"],["dc.identifier.pmid","29857860"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65371"],["dc.language.iso","en"],["dc.relation.eissn","1872-7727"],["dc.relation.issn","0720-048X"],["dc.title","Intra- and interobserver variability in the diagnosis of GERD by real-time MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","6653"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","6661"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Sprenger, Thilo"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Voit, Dirk"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Biggemann, Lorenz"],["dc.date.accessioned","2020-05-13T13:44:49Z"],["dc.date.available","2020-05-13T13:44:49Z"],["dc.date.issued","2019-12"],["dc.description.abstract","Purpose To assess the diagnostic potential of real-time MRI for assessment of hiatal hernias in patients with GERD-like symptoms compared to endoscopy. Material and methods One hundred eight patients with GERD-like symptoms were included in this observational cohort study between 2015 and 2017. Real-time MRI was performed at 3.0 Tesla with temporal resolution of 40 ms, dynamically visualizing the esophageal transport of a pineapple juice bolus, its passage through the gastroesophageal junction, and functional responses during Valsalva maneuver. Hernia detection on MRI and endoscopy was calculated using contingency tables with diagnosis of hernia on either modality as reference. Results Of 108 patients, 107 underwent successful MRI without adverse events; 1 examination was aborted to inability to swallow pineapple juice in supine position. No perforation or acute bleeding occurred during endoscopy. Median examination time was 15 min. Eighty-five patients (79.4%) were diagnosed with hiatal hernia on either real-time MRI or endoscopy. Forty-six hernias were visible on both modalities. Seventeen hernias were evident exclusively on MRI, and 22 exclusively on endoscopy. Sixteen of the 63 MRI-detected hernias (25.4%) were detectable only during Valsalva maneuver, which were smaller compared to hernias at rest (median − 13.5 vs − 33.0 mm, p < 0.001). Diagnostic accuracy for hernia detection was comparable for MRI and endoscopy (sensitivity 74% vs 80%, p = 0.4223; specificity 100% vs 100%, p > 0.99)."],["dc.identifier.doi","10.1007/s00330-019-06284-8"],["dc.identifier.pmid","31187219"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65367"],["dc.language.iso","en"],["dc.relation.eissn","1432-1084"],["dc.relation.issn","0938-7994"],["dc.title","Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]