Hosseini, Ali Seif Amir

[["dc.bibliographiccitation.artnumber","20180051"],["dc.bibliographiccitation.journal","BJR|case reports"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Biggemann, Lorenz"],["dc.contributor.author","Kahl, Fritz"],["dc.contributor.author","Ahmed, Saheeb"],["dc.contributor.author","Markus, Duersch"],["dc.date.accessioned","2019-07-09T11:45:57Z"],["dc.date.available","2019-07-09T11:45:57Z"],["dc.date.issued","2018"],["dc.description.abstract","Splenic torsion is an uncommon condition becoming clinically apparent when the spleen twists or rotates around the organ’s vascular pedicle. In the case of a wandering spleen the organ is only attached to an elongated vascular pedicle while the peritoneal attachments are absent. However, splenic torsion could also occur in patients with abnormal laxity of the splenic peritoneal attachments. We report a case of a splenic torsion due to absence of splenic ligaments with pancreatic volvulus and partial involvement of descending colon in a 9-year-old boy."],["dc.identifier.doi","10.1259/bjrcr.20180051"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15356"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59347"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2055-7159"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","Splenic torsion with involvement of pancreas and descending colon in a 9-year-old boy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","122"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Open Public Health Journal"],["dc.bibliographiccitation.lastpage","133"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Uhlig, Annemarie"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Strauss, Arne"],["dc.contributor.author","Trojan, Lutz"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.date.accessioned","2019-07-09T11:45:23Z"],["dc.date.available","2019-07-09T11:45:23Z"],["dc.date.issued","2018"],["dc.description.abstract","Purpose: To summarize the current evidence on preventive services utilization in cancer survivors. Methods: A systematic literature review and meta-analysis was conducted in February 2016. Studies were included if they compared the utilization of influenza vaccination, cholesterol/lipid testing, bone densitometry, or blood pressure measurement among survivors of adulthood cancer to cancer-free controls. Random effects meta-analyses were conducted to pool estimates. Results: Literature search identified 3740 studies of which 10 fulfilled the inclusion criteria. Cancer survivors were significantly more likely to utilize bone densitometry (OR=1.226, 95% CI: 1.114 – 1.350, p<0.001) and influenza vaccination (OR=1.565, 95% CI: 1.176 – 2.082, p=0.002) than cancer-free controls. No statistically significant differences were detected for blood pressure measurement and cholesterol/lipid testing (OR=1.322, 95% CI: 0.812 – 2.151, p=0.261; OR=1.046, 95% CI: 0.96 – 1.139, p=0.304). Conclusions: Cancer survivors were more likely to receive influenza vaccinations and bone densitometry. Future studies should evaluate underlying mechanisms and whether the utilization of preventive services translates into prolonged survival of cancer survivors. Implications for Cancer Survivors: Our meta-analysis demonstrated cancer survivors to be more likely to receive the preventive services such as influenza vaccination and bone densitometry than cancer free controls. Still, these results should be interpreted in the context of suboptimal utilization of preventive services in general, and for cancer survivors in specific. Future research should evaluate the underlying mechanisms and whether utilization of preventive services is associated with overall survival in cancer survivors."],["dc.identifier.doi","10.2174/1874944501811010122"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15190"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59219"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1874-9445"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","610"],["dc.title","Preventive Services Utilization Among Cancer Survivors Compared to Cancer-free Controls"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Diagnostics"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Hawellek, Thelonius; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.affiliation","Meier, Marc-Pascal; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.affiliation","Seitz, Mark-Tilman; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.affiliation","Uhlig, Johannes; 2Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075 Göttingen, Germany; johannes.uhlig@med.uni-goettingen.de (J.U.); ali.seif@med.uni-goettingen.de (A.S.A.H.)"],["dc.contributor.affiliation","Hosseini, Ali Seif Amir; 2Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075 Göttingen, Germany; johannes.uhlig@med.uni-goettingen.de (J.U.); ali.seif@med.uni-goettingen.de (A.S.A.H.)"],["dc.contributor.affiliation","Beil, Frank Timo; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.affiliation","Lehmann, Wolfgang; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.affiliation","Hubert, Jan; 1Department of Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; marc-pascal.meier@med.uni-goettingen.de (M.-P.M.); mark-tilmann.seitz@med.uni-goettingen.de (M.-T.S.); ft.beil@uke.de (F.T.B.); wolfgang.lehmann@med.uni-goettingen.de (W.L.); j.hubert@uke.de (J.H.)"],["dc.contributor.author","Hawellek, Thelonius"],["dc.contributor.author","Meier, Marc-Pascal"],["dc.contributor.author","Seitz, Mark-Tilman"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Beil, Frank Timo"],["dc.contributor.author","Lehmann, Wolfgang"],["dc.contributor.author","Hubert, Jan"],["dc.date.accessioned","2022-08-04T08:36:40Z"],["dc.date.available","2022-08-04T08:36:40Z"],["dc.date.issued","2022-07-22"],["dc.date.updated","2022-08-03T10:42:20Z"],["dc.description.abstract","Background: Physiological reference values for morphological parameters of the hip (MPH) are of clinical importance for the treatment of painful, degenerated or fractured hip joints, as well as to detect morphological deformities, which could result in early osteoarthritis of the hip. Currently, sufficient data for MPH are lacking. Therefore, it remains unclear if age-dependent alterations in adult hip morphology are physiological and if there are side- and gender-dependent differences. The aim of the study was to analyze MPH according to gender, side and age in a large-scaled cohort by CT scans. Methods: A total of 1576 hip joints from 788 patients (female: 257, male: 531; mean age: 58.3 years (±18.9; 18–92 years)) were analyzed by CT. For all hips, acetabular anteversion (AcetAV); lateral centrum edge angle (LCE); acetabular index (AI); femoral neck version (FNV); centrum-collum-diaphyseal angle (CCD); and anterior alpha angle (AαA) were measured. Results: The mean values in this cohort were: AcetAV 20.5° (±6.9); LCE 40.8° (±8.8); AI 0.3° (±5.3); FNV 11.0° (±9.8); CCD 129.9° (±7.4); and AαA 41.2° (±7.7). There was a detectable side-specific difference for AcetAV (p = 0.001); LCE (p < 0.001); CCD (p < 0.001); and AαA (p < 0.001). All the analyzed parameters showed a significant gender-specific difference, except for AI (p = 0.37). There was a significant correlation between age and AcetAV (r = 0.17; p < 0.001); LCE (r = 0.39; p < 0.001); AI (r = −0.25; p < 0.001); CCD (r = −0.15; p < 0.001); and AαA (r = 0.09; p < 0.001), except FNV (p = 0.79). Conclusions: There are side-, gender- and age-specific alterations in hip morphology, which have to be considered in treating hip joint pathologies."],["dc.description.sponsorship","University of Goettingen"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3390/diagnostics12081774"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112633"],["dc.language.iso","en"],["dc.relation.eissn","2075-4418"],["dc.rights","CC BY 4.0"],["dc.title","Morphological Parameters of the Hip Joint and Its Relation to Gender, Joint Side and Age—A CT-Based Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","681"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical & Experimental Metastasis"],["dc.bibliographiccitation.lastpage","693"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Krause, Petra"],["dc.contributor.author","Flikweert, H."],["dc.contributor.author","Monin, Malte B."],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Helms, G."],["dc.contributor.author","Cantanhede, G."],["dc.contributor.author","Ghadimi, B. Michael"],["dc.contributor.author","Koenig, S."],["dc.date.accessioned","2018-11-07T09:24:13Z"],["dc.date.available","2018-11-07T09:24:13Z"],["dc.date.issued","2013"],["dc.description.abstract","Nearly 50 % of colorectal cancer (CRC) patients develop liver metastases with liver resection being the only option to cure patients. Residual micrometastases or circulating tumor cells are considered a cause of tumor relapse. This work investigates the influence of partial hepatectomy (PH) on the growth and molecular composition of CRC liver metastasis in a syngeneic rat model. One million CC531 colorectal tumor cells were implanted via the portal vein in WAG/Rij rats followed by a 30 % PH a day later. Control groups either received tumor cells followed by a sham-operation or were injected with a buffer solution followed by PH. Animals were examined with magnetic resonance imaging (MRI) and liver tissues were processed for immunolabeling and PCR analysis. One-third PH was associated with an almost threefold increase in relative tumor mass (MRI volumetry: 2.8-fold and transcript levels of CD44: 2.3-fold). Expression of molecular markers for invasiveness and aggressiveness (CD49f, CXCR4, Axin2 and c-met) was increased following PH, however with no significant differences when referring to the relative expression levels (relating to tumor mass). Liver metastases demonstrated a significantly higher proliferation rate (Ki67) 2 weeks following PH and cell divisions also increased in the surrounding liver tissue. Following PH, the stimulated growth of metastases clearly exceeded the compensation in liver volume with long-lasting proliferative effects. However, the distinct tumor composition was not influenced by liver regeneration. Future investigations should focus on the inhibition of cell cycle (i.e. systemic therapy strategies, irradiation) to hinder liver regeneration and therefore restrain tumor growth."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft (DFG) [KO 2218/5-1]"],["dc.identifier.doi","10.1007/s10585-013-9572-y"],["dc.identifier.isi","000319345900013"],["dc.identifier.pmid","23385555"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11172"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29773"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0262-0898"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Increased growth of colorectal liver metastasis following partial hepatectomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2507"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Diagnostics"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Meier, Marc-Pascal; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Brandt, Lars Erik; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Saul, Dominik; 2BG Trauma Center Tuebingen, Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany"],["dc.contributor.affiliation","Roch, Paul Jonathan; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Klockner, Friederike Sophie; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Hosseini, Ali Seif Amir; 4Department of Diagnostic and Interventional Radiology, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Lehmann, Wolfgang; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.affiliation","Hawellek, Thelonius; 1Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany"],["dc.contributor.author","Meier, Marc-Pascal"],["dc.contributor.author","Brandt, Lars Erik"],["dc.contributor.author","Saul, Dominik"],["dc.contributor.author","Roch, Paul Jonathan"],["dc.contributor.author","Klockner, Friederike Sophie"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Lehmann, Wolfgang"],["dc.contributor.author","Hawellek, Thelonius"],["dc.date.accessioned","2022-12-01T08:31:39Z"],["dc.date.available","2022-12-01T08:31:39Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:12:20Z"],["dc.description.abstract","Background: Humeral offset (HO) and glenoidal offset (GO) are important morphological parameters in diagnostics and therapy for shoulder pathologies. However, physiological reference values have not yet been sufficiently determined. The aim of the present study was to establish physiological reference values for shoulder offset parameters (SOPs). Methods: MRI images of the shoulder joints of 800 patients (mean age: 50.13 years [±16.01]) were analysed retrospectively. HO, GO, lateral glenoidal humeral offset (LGHO), humeral shaft axis offset (HAO) and cortical offset (CO) were measured. SOPs were examined for associations with age, gender, side and osteoarthritis. Results: The mean HO was 26.19 (±2.70), the mean GO was 61.79 (±5.67), the mean LGHO was 54.49 (±4.69), the mean HAO was 28.17 (±2.82) and the mean CO was 16.70 (±3.08). For all SOPs, significantly higher values were measured in male shoulders. There was a significantly (p < 0.001) higher mean value for HO, GO and LGHO in right shoulders. There was a significant correlation between age and LGHO, and HAO and CO, but not between age and HO or GO. Shoulders with osteoarthritis and non-osteoarthritis did not differ in the mean value of HO, GO, LGHO and HAO, except for CO (p = 0.049). Conclusion: Reference values for SOPs in the adult shoulder joint were determined for the first time. Significant gender-specific differences were found for all measured SOPs. In addition, it was seen that for some SOPs, the joint side and the patient’s age has to be taken into account in shoulder diagnostics and surgery."],["dc.description.sponsorship","Open Access Publication Fund of the University of Goettingen"],["dc.identifier.doi","10.3390/diagnostics12102507"],["dc.identifier.pii","diagnostics12102507"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118227"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.eissn","2075-4418"],["dc.rights","CC BY 4.0"],["dc.title","Physiological Offset Parameters of the Adult Shoulder Joint—A MRI Study of 800 Patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","unpublished"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Neurology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Meyer, Stefanie; 1Department of Neurology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Kaulfuß, Silke; 2Department of Human Genetics, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Zechel, Sabrina; 3Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Kummer, Karsten; 1Department of Neurology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Seif Amir Hosseini, Ali; 4Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Ernst, Marielle Sophie; 5Department of Neuroradiology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Schmidt, Jens; 1Department of Neurology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Pauli, Silke; 2Department of Human Genetics, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Zschüntzsch, Jana; 1Department of Neurology, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.author","Meyer, Stefanie"],["dc.contributor.author","Kaulfuß, Silke"],["dc.contributor.author","Zechel, Sabrina"],["dc.contributor.author","Kummer, Karsten"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Ernst, Marielle Sophie"],["dc.contributor.author","Schmidt, Jens"],["dc.contributor.author","Pauli, Silke"],["dc.contributor.author","Zschüntzsch, Jana"],["dc.date.accessioned","2022-08-04T07:56:56Z"],["dc.date.available","2022-08-04T07:56:56Z"],["dc.date.issued","2022-07-19"],["dc.date.updated","2022-08-02T14:39:17Z"],["dc.description.abstract","Background\r\nBenefits and challenges resulting from advances in genetic diagnostics are two sides of the same coin. Facilitation of a correct and timely diagnosis is paralleled by challenges in interpretation of variants of unknown significance (VUS). Focusing on an individual VUS-re-classification pipeline, this study offers a diagnostic approach for clinically suspected hereditary muscular dystrophy by combining the expertise of an interdisciplinary team.\r\n\r\n\r\nMethods\r\nIn a multi-step approach, a thorough phenotype assessment including clinical examination, laboratory work, muscle MRI and histopathological evaluation of muscle was performed in combination with advanced Next Generation Sequencing (NGS). Different in-silico tools and prediction programs like Alamut, SIFT, Polyphen, MutationTaster and M-Cap as well as 3D- modeling of protein structure and RNA-sequencing were employed to determine clinical significance of the LAMA2 variants.\r\n\r\n\r\nResults\r\nTwo previously unknown sequence alterations in LAMA2 were detected, a missense variant was classified initially according to ACMG guidelines as a VUS (class 3) whereas a second splice site variant was deemed as likely pathogenic (class 4). Pathogenicity of the splice site variant was confirmed by mRNA sequencing and nonsense mediated decay (NMD) was detected. Combination of the detected variants could be associated to the LGMDR23-phenotype based on the MRI matching and literature research.\r\n\r\n\r\nDiscussion\r\nTwo novel variants in LAMA2 associated with LGMDR23-phenotype are described. This study illustrates challenges of the genetic findings due to their VUS classification and elucidates how individualized diagnostic procedure has contributed to the accurate diagnosis in the spectrum of LGMD."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3389/fneur.2022.893605"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112616"],["dc.language.iso","en"],["dc.relation.eissn","1664-2295"],["dc.rights","CC BY 4.0"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Evidence of Two Novel LAMA2 Variants in a Patient With Muscular Dystrophy: Facing the Challenges of a Certain Diagnosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]