Bauer, Christian R. K. D.

[["dc.bibliographiccitation.firstpage","35"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Veterinary Microbiology"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","160"],["dc.contributor.author","Schulz, Claudia"],["dc.contributor.author","Eschbaumer, Michael"],["dc.contributor.author","Ziller, Mario"],["dc.contributor.author","Waeckerlin, Regula"],["dc.contributor.author","Beer, Martin"],["dc.contributor.author","Gauly, Matthias"],["dc.contributor.author","Grevelding, Christoph G."],["dc.contributor.author","Hoffmann, Bernd"],["dc.contributor.author","Bauer, Christian R."],["dc.date.accessioned","2018-11-07T09:03:32Z"],["dc.date.available","2018-11-07T09:03:32Z"],["dc.date.issued","2012"],["dc.description.abstract","Bluetongue (BT) is a major disease of ruminant livestock that can have a substantial impact on income and animal welfare. In South American camelids (SAC), fatalities related to bluetongue virus (BTV) infection were reported in Germany and France during the recent BTV-8 and BTV-1 epizootics, which raised concern about the role of SAC in the epidemiology of BTV. Therefore, a large-scale serological and virological study was conducted in Germany from autumn 2008 to spring 2009. Risk factors associated with BTV infection were analysed by multiple logistic regression. These included age, species, gender and housing arrangements of SAC as well as the location of the herds and the presence of ruminants on farms.Altogether, 249 (14.3%) of 1742 SAC were found seropositive by BTV ELISA, and 43 (47.3%) of the 91 herds had at least one BTV-seropositive SAC. However, no BTV RNA was detected in any of the seropositive samples. Seroprevalence depended on the sampling region and probably on age, but not on any other analysed risk factors associated with BTV infection in ruminants. The highest seroprevalence was found in the west of Germany where the BTV-8 epizootic started in 2006. Recorded BTV-8 related disease and fatalities are discussed. Although the prevalence of BTV-8 antibodies was high in some regions, the virological results indicate that SAC play a negligible role in the epidemiology of this virus infection. (C) 2012 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.vetmic.2012.05.028"],["dc.identifier.isi","000310418300006"],["dc.identifier.pmid","22704245"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24915"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0378-1135"],["dc.title","Cross-sectional study of bluetongue virus serotype 8 infection in South American camelids in Germany (2008/2009)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","272"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Veterinary Parasitology"],["dc.bibliographiccitation.lastpage","281"],["dc.bibliographiccitation.volume","214"],["dc.contributor.author","Schulz, Claudia"],["dc.contributor.author","Ziller, Mario"],["dc.contributor.author","Kampen, Helge"],["dc.contributor.author","Gauly, Matthias"],["dc.contributor.author","Beer, Martin"],["dc.contributor.author","Grevelding, Christoph G."],["dc.contributor.author","Hoffmann, Bernd"],["dc.contributor.author","Bauer, Christian R."],["dc.contributor.author","Werner, Doreen"],["dc.date.accessioned","2018-11-07T09:47:29Z"],["dc.date.available","2018-11-07T09:47:29Z"],["dc.date.issued","2015"],["dc.description.abstract","Palearctic species of Culicoides (Diptera, Ceratopogonidae), in particular of the Obsoletus and Pulicaris complexes, were identified as putative vectors of bluetongue virus serotype 8 (BTV-8) on ruminant farms during the epizootic in Germany from 2006 to 2009. BTV may cause severe morbidity and mortality in ruminants and sporadically in South American camelids (SAC). However, the fauna of Culicoides spp. on SAC farms has not been investigated. Therefore, the ceratopogonid fauna was monitored on three farms with BTV-seropositive SAC in Germany. Black-light traps were set up on pastures and in stables from summer 2008 to autumn 2009. Additionally, ceratopogonids were caught in emergence traps mounted on llama dung and dung-free pasture from spring to autumn 2009. After morphological identification, selected Culicoides samples were analysed for BTV-RNA by real-time RT-PCR. The effects of the variables 'location', 'temperature' and 'humidity' on the number of Culicoides caught in black-light traps were modelled using multivariable Poisson regression. In total, 26 species of Culicoides and six other genera of biting midges were identified. The most abundant Culicoides spp. collected both outdoors and indoors with black-light traps belonged to the Obsoletus (77.4%) and Pulicaris (16.0%) complexes. The number of Culicoides peaked in summer, while no biting midges were caught during the winter months. Daily collections of Culicoides were mainly influenced by the location and depended on the interaction of temperature and humidity. In the emergence traps, species of the Obsoletus complex predominated the collections. In summary, the absence of BTV-RNA in any of the analysed Culicoides midges and in the BTV-seropositive SAC on the three farms together with the differences in the pathogenesis of BTV-8 in SAC compared to ruminants suggests a negligible role of SAC in the spread of the virus. Although SAC farms may provide similar suitable habitats for putative Culicoides vectors than ruminant farms, the results suggest that geographic and meteorological factors had a stronger influence on Culicoides abundance than the animal species. (C) 2015 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.vetpar.2015.09.021"],["dc.identifier.isi","000367112600006"],["dc.identifier.pmid","26489592"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35123"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-2550"],["dc.relation.issn","0304-4017"],["dc.title","Culicoides vector species on three South American camelid farms seropositive for bluetongue virus serotype 8 in Germany 2008/2009"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","257"],["dc.bibliographiccitation.issue","3-4"],["dc.bibliographiccitation.journal","Veterinary Microbiology"],["dc.bibliographiccitation.lastpage","265"],["dc.bibliographiccitation.volume","154"],["dc.contributor.author","Schulz, Claudia"],["dc.contributor.author","Eschbaumer, Michael"],["dc.contributor.author","Rudolf, Miriam"],["dc.contributor.author","Koenig, Patricia"],["dc.contributor.author","Keller, Markus"],["dc.contributor.author","Bauer, Christian R."],["dc.contributor.author","Gauly, Matthias"],["dc.contributor.author","Grevelding, Christoph G."],["dc.contributor.author","Beer, Martin"],["dc.contributor.author","Hoffmann, Bernd"],["dc.date.accessioned","2018-11-07T09:14:15Z"],["dc.date.available","2018-11-07T09:14:15Z"],["dc.date.issued","2012"],["dc.description.abstract","Bluetongue (BT) is an infectious, non-contagious disease of wild and domestic ruminants. It is caused by bluetongue virus (BTV) and transmitted by Culicoides biting midges. Since 1998, BT has been emerging throughout Europe, threatening not only the naive ruminant population. Historically, South American camelids (SAC) were considered to be resistant to BT disease. However, recent fatalities related to BTV in captive SAC have raised questions about their role in BTV epidemiology. Data on the susceptibility of SAC to experimental infection with BTV serotype 8 (BTV-8) were collected in an animal experiment. Three alpacas (Vicugna pacos) and three llamas (Lama glama) were experimentally infected with BTV-8. They displayed very mild clinical signs. Seroconversion was first measured 6-8 days after infection (dpi) by ELISA, and neutralising antibodies appeared 10-13 dpi. BTV-8 RNA levels in blood were very low, and quickly cleared after seroconversion. However, spleens collected post-mortem were still positive for BTV RNA, over 71 days after the last detection in blood samples. Virus isolation was only possible from blood samples of two alpacas by inoculation of highly sensitive interferon alpha/beta receptor-deficient (IFNAR(-/-)) mice. An in vitro experiment demonstrated that significantly lower amounts of BTV-8 adsorb to SAC blood cells than to bovine blood cells. Although this experiment showed that SAC are generally susceptible to a BTV-8 infection, it indicates that these species play a negligible role in BTV epidemiology. (C) 2011 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.vetmic.2011.07.025"],["dc.identifier.isi","000299582000006"],["dc.identifier.pmid","21862245"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27366"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1873-2542"],["dc.relation.issn","0378-1135"],["dc.title","Experimental infection of South American camelids with bluetongue virus serotype 8"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]