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Puls, Miriam
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Puls, Miriam
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Puls, Miriam
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Puls, M.
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2017Journal Article [["dc.bibliographiccitation.firstpage","286"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","EuroIntervention"],["dc.bibliographiccitation.lastpage","293"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Korte, Kerstin Pia"],["dc.contributor.author","Bleckmann, Annalen"],["dc.contributor.author","Huenlich, Mark"],["dc.contributor.author","Danner, Bernhard"],["dc.contributor.author","Schoendube, Friedrich"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.date.accessioned","2021-06-01T10:48:55Z"],["dc.date.available","2021-06-01T10:48:55Z"],["dc.date.issued","2017"],["dc.description.abstract","AIMS: The objective of this study was to examine the impact of guideline-defined subtypes of severe aortic stenosis (AS) on long-term outcomes after TAVI. METHODS AND RESULTS: Four hundred (400) consecutive patients who underwent TAVI (203 transapical, 197 transfemoral) at our institution 8/2008-3/2013 were followed systematically (for up to seven years). One hundred and forty-seven (147) individuals suffered from NEF-HG AS (LV-EF ≥50%, high Pmean ≥40 mmHg), 63 from LEF-HG AS (LV-EF <50%, high gradient), 77 from PLF-LG AS (LV-EF ≥50%, low gradient, stroke volume index [SVI] <35 ml/m²), and 81 from LEF-LG AS (LV-EF <50%, low gradient). LEF-LG status was associated with the highest all-cause and cardiovascular mortality and MACCE rate, whereas NEF-HG patients exhibited the best outcome (i.e., median survival 5.1 years in NEF-HG vs. 1.3 years in LEF-LG, p=0.0006; or vs. 3.3 years in PLF-LG, p=0.02). In multivariate analysis, LEF-LG status emerged as the outcome predictor with the highest hazard ratio for all-cause mortality (HR 2.86, p=0.003), cardiovascular mortality (HR 6.53, p<0.0001), and MACCE (HR 2.44, p=0.007), whereas neither baseline EF nor SVI <35 ml/m² independently predicted these endpoints. CONCLUSIONS: These findings suggest that an assessment of LV-EF alone for outcome prediction after TAVI is inadequate; it is the guideline-defined subtype of AS that determines outcome."],["dc.identifier.doi","10.4244/EIJ-D-16-00801"],["dc.identifier.gro","3142338"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86102"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","final"],["dc.relation.issn","1774-024X"],["dc.title","Long-term outcomes after TAVI in patients with different types of aortic stenosis: the conundrum of low flow, low gradient and low ejection fraction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]Details DOI2008Conference Abstract [["dc.bibliographiccitation.issue","18"],["dc.bibliographiccitation.journal","Circulation"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Dallas, Claudia"],["dc.contributor.author","Lankeit, Mareike K."],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Schaefer, Katrin"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Konstantinides, Stavros V."],["dc.date.accessioned","2018-11-07T11:09:52Z"],["dc.date.available","2018-11-07T11:09:52Z"],["dc.date.issued","2008"],["dc.format.extent","S621"],["dc.identifier.isi","000262104501728"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53094"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","81st Annual Scientific Session of the American-Heart-Association"],["dc.relation.eventlocation","New Orleans, LA"],["dc.relation.issn","0009-7322"],["dc.title","Heart-Type Fatty Acid-Binding Protein Predicts Outcome In Normotensive Patients With Pulmonary Embolism"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details WOS2015Conference Abstract [["dc.bibliographiccitation.firstpage","27"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","28"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.contributor.author","Lubos, Edith"],["dc.contributor.author","Boekstegers, Peter"],["dc.contributor.author","von Bardeleben, R. S."],["dc.contributor.author","Butter, Christian"],["dc.contributor.author","Zuern, Christine S."],["dc.contributor.author","Ouarrak, Taoufik"],["dc.contributor.author","Eggebrecht, Holger"],["dc.contributor.author","Senges, Jochen"],["dc.date.accessioned","2018-11-07T09:53:28Z"],["dc.date.available","2018-11-07T09:53:28Z"],["dc.date.issued","2015"],["dc.identifier.isi","000361205101093"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36337"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.conference","Congress of the European-Society-of-Cardiology (ESC)"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","One-year outcome after mitraclip implantation - Results from the German TRAMI registry"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details WOS2016Journal Article [["dc.bibliographiccitation.firstpage","323"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Der Internist"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.date.accessioned","2018-11-07T10:16:25Z"],["dc.date.available","2018-11-07T10:16:25Z"],["dc.date.issued","2016"],["dc.description.abstract","The percutaneous edge-to-edge mitral valve repair with MitraClipA (R) is evolving as a potential alternative to conventional surgery in high-risk patients with significant mitral regurgitation (MR). The randomized controlled EVEREST II-trial which compared percutaneous repair versus surgery in operable patients with symptomatic severe MR demonstrated superior safety of MitraClipA (R) implantation but better MR reduction after surgery at 12 months. However, large registries on MitraClipA (R) therapy showed that real-world MitraClipA (R) patients differ significantly from the EVEREST II-cohort: they are older, in more advanced stages of heart failure, present predominantly with secondary MR, and exhibit a higher burden of comorbidities. For these patients, registry data confirm a low incidence of peri-interventional complications and a significant improvement of heart failure symptoms and quality of life measures after MitraClipA (R) implantation. The ongoing RESHAPE trial with randomization of MitraClipA (R) implantation against optimal medical therapy investigates a possible survival benefit after MitraClipA (R) in patients with secondary MR."],["dc.identifier.doi","10.1007/s00108-016-0033-y"],["dc.identifier.isi","000373226300004"],["dc.identifier.pmid","26968857"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41036"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1289"],["dc.relation.issn","0020-9554"],["dc.title","Catheter-based mitral valve repair by MitraClip implantation. Development, studies, and use in clinical practice"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2015Journal Article [["dc.bibliographiccitation.firstpage","1044"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","1053"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Zuern, Christine S."],["dc.contributor.author","Bauer, Axel"],["dc.contributor.author","Lubos, Edith"],["dc.contributor.author","Boekstegers, Peter"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","von Bardeleben, Ralph Stephan"],["dc.contributor.author","Ouarrak, Taoufik"],["dc.contributor.author","Butter, Christian"],["dc.contributor.author","Eggebrecht, Holger"],["dc.contributor.author","Nickenig, Georg"],["dc.contributor.author","Zahn, Ralph"],["dc.contributor.author","Senges, Jochen"],["dc.contributor.author","May, Andreas E."],["dc.date.accessioned","2018-11-07T09:48:35Z"],["dc.date.available","2018-11-07T09:48:35Z"],["dc.date.issued","2015"],["dc.description.abstract","Aims To investigate the influence of non-cardiac comorbidities on outcomes of patients enrolled in the German transcatheter mitral valve interventions (TRAMI) registry. Methods and resultsIntrahospital and 30-day MACCE rates (death of all causes, stroke and myocardial infarction) of 828 patients from the TRAMI registry were stratified by the number of non-cardiac comorbidities. The following non-cardiac comorbidities were prospectively recorded in the registry: diabetes, renal insufficiency, extracardiac arteriopathy, chronic lung disease, neurological disease or malignancy on palliative care. The 375 (45.3 %) patients with multiple (a parts per thousand yen2) non-cardiac comorbidities presented with higher NYHA classes, higher logistic Euroscores, higher levels of NT-proBNP and a shorter 6-min walk distance. Rates of intraprocedural death (0.3 vs. 0.0 %, p = 0.41) and intrahospital MACCE (3.6 vs. 1.9 %, p = 0.16) were not significantly higher in patients with multiple non-cardiac comorbidities, but 30-day MACCE rate was significantly enhanced (6.4 vs. 3.6 %, p = 0.049). However, both patient groups showed a similar clinical improvement after 30 days. Renal insufficiency was the only non-cardiac comorbidity which was independently associated with the 30-day MACCE rate. ConclusionsMitraClip device placement is feasible and safe in patients with multiple non-cardiac comorbidities resulting in a significant clinical improvement and acceptable intrahospital and 30-day event rates. Renal failure is an independent predictor of outcome."],["dc.identifier.doi","10.1007/s00392-015-0872-x"],["dc.identifier.isi","000365307300005"],["dc.identifier.pmid","26022739"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35336"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0692"],["dc.relation.issn","1861-0684"],["dc.title","Influence of non-cardiac comorbidities on outcome after percutaneous mitral valve repair: results from the German transcatheter mitral valve interventions (TRAMI) registry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2016Journal Article Research Paper [["dc.bibliographiccitation.firstpage","107"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","111"],["dc.bibliographiccitation.volume","220"],["dc.contributor.author","Tichelbäcker, Tobias"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Jacobshagen, Claudius"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.contributor.author","Huenlich, Mark"],["dc.contributor.author","Schroeter, Marco Robin"],["dc.date.accessioned","2017-09-07T11:44:37Z"],["dc.date.available","2017-09-07T11:44:37Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Percutaneous mitral valve repair using MitraClip (R) (MC) is a well-established method for a subset of patients with severe mitral regurgitation (MR) and high risk for surgical intervention. Amplatzer (R) Cardiac Plug (ACP) occludes left atrial appendage and allows the discontinuation of oral anticoagulation and prevention of thromboembolic stroke. Due to the need for femoral and transseptal access in both procedures, a single approach could lead to minor risk of further complications and shorter cumulative intervention time. Methods: We systematically analysed all four patients who underwent a combined procedure with MC and ACP in our heart-centre. All procedures were performed under fluoroscopic as well as echocardiographic guidance, and follow-up controls in a midterm period were carried out. Results: In all patients (2 male/female; age 73-88 years), MC (1-2 Clips) and ACP (size 18-28mm) were successfully implanted in one procedure (mean total time: 114 +/- 17 min). At least moderate MR was achieved and two patients had no complications and therefore were discharged early. In a third patient, a dislocation of ACP occurred 2 h after the implantation. The oldest patient developed a respiratory insufficiency due to cardiac decompensation and further complications. Conclusion: A combination of MC and ACP in a single procedure was feasible in this first case series of patients without a significant extension of procedure time. However, it might be important to select patients carefully. The location of optimal transseptal puncture may be challenging in regard to ACP placement, even in experienced hands and subsequent complications can occur. (C) 2016 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.ijcard.2016.06.170"],["dc.identifier.gro","3141615"],["dc.identifier.isi","000381582000019"],["dc.identifier.pmid","27389439"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1456"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Abbott Vascular; St. Jude Medical"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.eissn","1874-1754"],["dc.relation.issn","0167-5273"],["dc.title","MitraClip (R) and Amplatzer (R) cardiac plug implantation in a single procedure: A reasonable approach?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2017Journal Article [["dc.bibliographiccitation.firstpage","241"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","248"],["dc.bibliographiccitation.volume","107"],["dc.contributor.author","Ledwoch, Jakob"],["dc.contributor.author","Franke, Jennifer"],["dc.contributor.author","Lubos, Edith"],["dc.contributor.author","Boekstegers, Peter"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Ouarrak, Taoufik"],["dc.contributor.author","von Bardeleben, Stephan"],["dc.contributor.author","Butter, Christian"],["dc.contributor.author","Schofer, Joachim"],["dc.contributor.author","Zahn, Ralf"],["dc.contributor.author","Ince, Hüsseyin"],["dc.contributor.author","Senges, Jochen"],["dc.contributor.author","Sievert, Horst"],["dc.date.accessioned","2020-12-10T14:10:21Z"],["dc.date.available","2020-12-10T14:10:21Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00392-017-1177-z"],["dc.identifier.eissn","1861-0692"],["dc.identifier.issn","1861-0684"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70735"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prognostic value of preprocedural 6-min walk test in patients undergoing transcatheter mitral valve repair—insights from the German transcatheter mitral valve interventions registry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2013Journal Article [["dc.bibliographiccitation.firstpage","896"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Catheterization and Cardiovascular Interventions"],["dc.bibliographiccitation.lastpage","900"],["dc.bibliographiccitation.volume","81"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Seipelt, Ralf G."],["dc.contributor.author","Schillinger, Wolfgang"],["dc.date.accessioned","2018-11-07T09:26:37Z"],["dc.date.available","2018-11-07T09:26:37Z"],["dc.date.issued","2013"],["dc.description.abstract","Objectives and Background The evidence of multiple percutaneous cardiac procedures in patients with numerous concomitant cardiac pathologies is limited. Methods and Results We report on the case of a 90-year-old male patient presenting with advanced heart failure because of degenerative aortic valve stenosis and degenerative mitral valve regurgitation. Moreover, significant coronary artery disease and intolerance of anticoagulation in atrial fibrillation were present. The patient was rejected from surgery because of age and frailty and underwent a staged interventional procedure with percutaneous coronary intervention, followed by transfemoral aortic valve implantation with Edwards Sapien XT, percutaneous mitral valve repair with MitraClip, and left atrial appendage closure with Amplatzer Cardiac Plug. The last procedure was complicated by pericardial tamponade necessitating pericardial drainage. Eight weeks later, the patient reported on the absence of dyspnea in activities of daily living and a significant gain in quality of live. Conclusions The case demonstrates feasibility of a staged interventional approach in a select high-risk patient. (c) 2012 Wiley Periodicals, Inc."],["dc.description.sponsorship","Edwards Lifesciences; AGA Medical; Abbott Vascular"],["dc.identifier.doi","10.1002/ccd.24448"],["dc.identifier.isi","000316691300028"],["dc.identifier.pmid","22511369"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30339"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1522-1946"],["dc.title","Complete interventional heart repair of multiple concomitant cardiac pathologies in a staged approach"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2020Journal Article [["dc.bibliographiccitation.firstpage","87"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","92"],["dc.bibliographiccitation.volume","300"],["dc.contributor.author","Kalbacher, Daniel"],["dc.contributor.author","Daubmann, Anne"],["dc.contributor.author","Tigges, Eike"],["dc.contributor.author","Hünlich, Marc"],["dc.contributor.author","Wiese, Sabrina"],["dc.contributor.author","Conradi, Lenard"],["dc.contributor.author","Schirmer, Johannes"],["dc.contributor.author","Beuthner, Bo Eric"],["dc.contributor.author","Reichenspurner, Hermann"],["dc.contributor.author","Wegscheider, Karl"],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Tichelbäcker, Tobias"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schäfer, Ulrich"],["dc.contributor.author","Blankenberg, Stefan"],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Schillinger, Wolfang"],["dc.contributor.author","Lubos, Edith"],["dc.date.accessioned","2021-04-14T08:27:38Z"],["dc.date.available","2021-04-14T08:27:38Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.ijcard.2019.09.027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82358"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0167-5273"],["dc.title","Impact of pre- and post-procedural renal dysfunction on long-term outcomes in patients undergoing MitraClip implantation: A retrospective analysis from two German high-volume centres"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2003Conference Abstract [["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Therapeutic Drug Monitoring"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Binder, L."],["dc.contributor.author","Puls, Miriam"],["dc.contributor.author","Niedmann, P. D."],["dc.contributor.author","Pouwels, Claudia"],["dc.contributor.author","Nacke, A."],["dc.contributor.author","Oellerich, M."],["dc.contributor.author","Binder, Claudia"],["dc.date.accessioned","2018-11-07T10:37:31Z"],["dc.date.available","2018-11-07T10:37:31Z"],["dc.date.issued","2003"],["dc.format.extent","496"],["dc.identifier.isi","000184445500054"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45586"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology"],["dc.relation.eventlocation","BASEL, SWITZERLAND"],["dc.relation.issn","0163-4356"],["dc.title","A simple and rapid HPLC method for the determination of meropenem - Preanalytical and analytical aspects"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details WOS