Anker, Stefan Dietmar

[["dc.bibliographiccitation.firstpage","906"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","910"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Pozzoli, Massimo"],["dc.contributor.author","Gonzalez‐Costello, Jose"],["dc.contributor.author","Bayes‐Genis, Antoni"],["dc.contributor.author","Sinagra, Gianfranco"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Coats, Andrew J.S."],["dc.contributor.author","Crespo‐Leiro, Marisa G."],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Laroche, Cécile"],["dc.contributor.author","Maggioni, Aldo P."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Piepoli, Massimo F."],["dc.contributor.author","Tavazzi, Luigi"],["dc.date.accessioned","2020-12-10T14:06:19Z"],["dc.date.available","2020-12-10T14:06:19Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1002/ejhf.v22.5"],["dc.identifier.eissn","1879-0844"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69855"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prevalence of risk of thrombosis and of bleeding and antithrombotic treatment in patients with heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","391"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","412"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Tschöpe, Carsten"],["dc.contributor.author","Boer, Rudolf A."],["dc.contributor.author","Fraser, Alan G."],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Donal, Erwan"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Fu, Michael"],["dc.contributor.author","Guazzi, Marco"],["dc.contributor.author","Lam, Carolyn S.P."],["dc.contributor.author","Lancellotti, Patrizio"],["dc.contributor.author","Melenovsky, Vojtech"],["dc.contributor.author","Morris, Daniel A."],["dc.contributor.author","Nagel, Eike"],["dc.contributor.author","Pieske-Kraigher, Elisabeth"],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Solomon, Scott D."],["dc.contributor.author","Vasan, Ramachandran S."],["dc.contributor.author","Rutten, Frans H."],["dc.contributor.author","Voors, Adriaan A."],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Seferovic, Petar"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.date.accessioned","2020-12-10T14:06:19Z"],["dc.date.available","2020-12-10T14:06:19Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/eurheartj/ehz641"],["dc.identifier.eissn","1879-0844"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69854"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","54"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","65"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Targher, Giovanni"],["dc.contributor.author","Dauriz, Marco"],["dc.contributor.author","Laroche, Cécile"],["dc.contributor.author","Temporelli, Pier Luigi"],["dc.contributor.author","Hassanein, Mahmoud"],["dc.contributor.author","Seferovic, Petar M."],["dc.contributor.author","Drozdz, Jaroslaw"],["dc.contributor.author","Ferrari, Roberto"],["dc.contributor.author","Anker, Stephan"],["dc.contributor.author","Coats, Andrew"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Crespo-Leiro, Maria G."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Piepoli, Massimo F."],["dc.contributor.author","Maggioni, Aldo Pietro"],["dc.contributor.author","Tavazzi, Luigi"],["dc.date.accessioned","2020-12-10T14:06:22Z"],["dc.date.available","2020-12-10T14:06:22Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1002/ejhf.679"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69869"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","In-hospital and 1-year mortality associated with diabetes in patients with acute heart failure: results from the ESC-HFA Heart Failure Long-Term Registry"],["dc.title.alternative","Acute heart failure and diabetes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1956"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","New England Journal of Medicine"],["dc.bibliographiccitation.lastpage","1964"],["dc.bibliographiccitation.volume","376"],["dc.contributor.author","Packer, Milton"],["dc.contributor.author","O’Connor, Christopher"],["dc.contributor.author","McMurray, John J.V."],["dc.contributor.author","Wittes, Janet"],["dc.contributor.author","Abraham, William T."],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Dickstein, Kenneth"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Holcomb, Richard"],["dc.contributor.author","Krum, Henry"],["dc.contributor.author","Maggioni, Aldo P."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Peacock, W. Frank"],["dc.contributor.author","Petrie, Mark C."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","van Veldhuisen, Dirk J."],["dc.contributor.author","Kowarski, Lisa S."],["dc.contributor.author","Schactman, Mark"],["dc.contributor.author","Holzmeister, Johannes"],["dc.date.accessioned","2020-12-10T18:12:31Z"],["dc.date.available","2020-12-10T18:12:31Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND In patients with acute heart failure, early intervention with an intravenous vasodilator has been proposed as a therapeutic goal to reduce cardiac-wall stress and, potentially, myocardial injury, thereby favorably affecting patients' long-term prognosis. METHODS In this double-blind trial, we randomly assigned 2157 patients with acute heart failure to receive a continuous intravenous infusion of either ularitide at a dose of 15 ng per kilogram of body weight per minute or matching placebo for 48 hours, in addition to accepted therapy. Treatment was initiated a median of 6 hours after the initial clinical evaluation. The coprimary outcomes were death from cardiovascular causes during a median follow-up of 15 months and a hierarchical composite end point that evaluated the initial 48-hour clinical course. RESULTS Death from cardiovascular causes occurred in 236 patients in the ularitide group and 225 patients in the placebo group (21.7% vs. 21.0%; hazard ratio, 1.03; 96% confidence interval, 0.85 to 1.25; P=0.75). In the intention-to-treat analysis, there was no significant between-group difference with respect to the hierarchical composite outcome. The ularitide group had greater reductions in systolic blood pressure and in levels of N-terminal pro-brain natriuretic peptide than the placebo group. However, changes in cardiac troponin T levels during the infusion did not differ between the two groups in the 55% of patients with paired data. CONCLUSIONS In patients with acute heart failure, ularitide exerted favorable physiological effects (without affecting cardiac troponin levels), but short-term treatment did not affect a clinical composite end point or reduce long-term cardiovascular mortality. (Funded by Cardiorentis; TRUE-AHF ClinicalTrials.gov number, NCT01661634.)"],["dc.identifier.doi","10.1056/NEJMoa1601895"],["dc.identifier.eissn","1533-4406"],["dc.identifier.isi","000401407500009"],["dc.identifier.issn","0028-4793"],["dc.identifier.pmid","28402745"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74406"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Massachusetts Medical Soc"],["dc.relation.issn","1533-4406"],["dc.relation.issn","0028-4793"],["dc.title","Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","613"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","625"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Crespo-Leiro, Maria G."],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Maggioni, Aldo P."],["dc.contributor.author","Coats, Andrew J."],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","Ferrari, Roberto"],["dc.contributor.author","Piepoli, Massimo Francesco"],["dc.contributor.author","Delgado Jimenez, Juan F."],["dc.contributor.author","Metra, Marco"],["dc.contributor.author","Fonseca, Candida"],["dc.contributor.author","Hradec, Jaromir"],["dc.contributor.author","Amir, Offer"],["dc.contributor.author","Logeart, Damien"],["dc.contributor.author","Dahlström, Ulf"],["dc.contributor.author","Merkely, Bela"],["dc.contributor.author","Drozdz, Jaroslaw"],["dc.contributor.author","Goncalvesova, Eva"],["dc.contributor.author","Hassanein, Mahmoud"],["dc.contributor.author","Chioncel, Ovidiu"],["dc.contributor.author","Lainscak, Mitja"],["dc.contributor.author","Seferovic, Petar M."],["dc.contributor.author","Tousoulis, Dimitris"],["dc.contributor.author","Kavoliuniene, Ausra"],["dc.contributor.author","Fruhwald, Friedrich"],["dc.contributor.author","Fazlibegovic, Emir"],["dc.contributor.author","Temizhan, Ahmet"],["dc.contributor.author","Gatzov, Plamen"],["dc.contributor.author","Erglis, Andrejs"],["dc.contributor.author","Laroche, Cécile"],["dc.contributor.author","Mebazaa, Alexandre"],["dc.date.accessioned","2020-12-10T14:06:21Z"],["dc.date.available","2020-12-10T14:06:21Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1002/ejhf.566"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69865"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions"],["dc.title.alternative","ESC-HF-LT: 1-year follow-up"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","606"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Heart"],["dc.bibliographiccitation.lastpage","613"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Ferreira, João Pedro"],["dc.contributor.author","Rossignol, Patrick"],["dc.contributor.author","Demissei, Biniyam"],["dc.contributor.author","Sharma, Abhinav"],["dc.contributor.author","Girerd, Nicolas"],["dc.contributor.author","Anker, Stefan D"],["dc.contributor.author","Cleland, John G"],["dc.contributor.author","Dickstein, Kenneth"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Hillege, Hans L"],["dc.contributor.author","Lang, Chim C"],["dc.contributor.author","Metra, Marco"],["dc.contributor.author","Ng, Leong L"],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Samani, Nilesh J"],["dc.contributor.author","van Veldhuisen, Dirk J"],["dc.contributor.author","Zwinderman, Aeilko H"],["dc.contributor.author","Voors, Adriaan"],["dc.contributor.author","Zannad, Faiez"],["dc.date.accessioned","2020-12-10T18:37:15Z"],["dc.date.available","2020-12-10T18:37:15Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1136/heartjnl-2017-311750"],["dc.identifier.eissn","1468-201X"],["dc.identifier.issn","1355-6037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76891"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Coronary angiography in worsening heart failure: determinants, findings and prognostic implications"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","228"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Journal of the American Society of Nephrology"],["dc.bibliographiccitation.lastpage","239"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Emmens, Johanna E."],["dc.contributor.author","de Borst, Martin H."],["dc.contributor.author","Boorsma, Eva M."],["dc.contributor.author","Damman, Kevin"],["dc.contributor.author","Navis, Gerjan"],["dc.contributor.author","van Veldhuisen, Dirk J."],["dc.contributor.author","Dickstein, Kenneth"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Lang, Chim C."],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","ter Maaten, Jozine M."],["dc.date.accessioned","2022-04-01T10:01:21Z"],["dc.date.available","2022-04-01T10:01:21Z"],["dc.date.issued","2022"],["dc.description.abstract","Background and objectives The estimated glomerular filtration rate (eGFR) is a crucial parameter in heart failure. Much less is known about the importance of tubular function. We addressed the effect of tubular maximum phosphate reabsorption capacity (TmP/GFR), a parameter of proximal tubular function, in patients with heart failure. Design, setting, participants, & measurements We established TmP/GFR (Bijvoet formula) in 2085 patients with heart failure and studied its association with deterioration of kidney function (>25% eGFR decrease from baseline) and plasma neutrophil gelatinase–associated lipocalin (NGAL) doubling (baseline to 9 months) using logistic regression analysis and clinical outcomes using Cox proportional hazards regression. Additionally, we evaluated the effect of sodium-glucose transport protein 2 (SGLT2) inhibition by empagliflozin on tubular maximum phosphate reabsorption capacity in 78 patients with acute heart failure using analysis of covariance. Results Low TmP/GFR (<0.80 mmol/L) was observed in 1392 (67%) and 21 (27%) patients. Patients with lower TmP/GFR had more advanced heart failure, lower eGFR, and higher levels of tubular damage markers. The main determinant of lower TmP/GFR was higher fractional excretion of urea ( P <0.001). Lower TmP/GFR was independently associated with higher risk of plasma NGAL doubling (odds ratio, 2.20; 95% confidence interval, 1.05 to 4.66; P =0.04) but not with deterioration of kidney function. Lower TmP/GFR was associated with higher risk of all-cause mortality (hazard ratio, 2.80; 95% confidence interval, 1.37 to 5.73; P =0.005), heart failure hospitalization (hazard ratio, 2.29; 95% confidence interval, 1.08 to 4.88; P =0.03), and their combination (hazard ratio, 1.89; 95% confidence interval, 1.07 to 3.36; P =0.03) after multivariable adjustment. Empagliflozin significantly increased TmP/GFR compared with placebo after 1 day ( P =0.004) but not after adjustment for eGFR change. Conclusions TmP/GFR, a measure of proximal tubular function, is frequently reduced in heart failure, especially in patients with more advanced heart failure. Lower TmP/GFR is furthermore associated with future risk of plasma NGAL doubling and worse clinical outcomes, independent of glomerular function."],["dc.identifier.doi","10.2215/CJN.03720321"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105659"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","1555-905X"],["dc.relation.issn","1555-9041"],["dc.title","Assessment of Proximal Tubular Function by Tubular Maximum Phosphate Reabsorption Capacity in Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.contributor.author","Usman, Muhammad Shariq"],["dc.contributor.author","Khan, Muhammad Shahzeb"],["dc.contributor.author","Fonarow, Gregg C."],["dc.contributor.author","Greene, Stephen J."],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Vaduganathan, Muthiah"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Coats, Andrew J. Stewart"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Butler, Javed"],["dc.date.accessioned","2022-02-01T10:31:07Z"],["dc.date.available","2022-02-01T10:31:07Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1002/ehf2.13785"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98786"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.eissn","2055-5822"],["dc.relation.issn","2055-5822"],["dc.title","Robustness of outcomes in trials evaluating sodium–glucose co‐transporter 2 inhibitors for heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.contributor.author","Butler, Javed"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Siddiqi, Tariq Jamal"],["dc.contributor.author","Coats, Andrew J.S."],["dc.contributor.author","Dorigotti, Fabio"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Göhring, Udo‐Michael"],["dc.contributor.author","Kosiborod, Mikhail N."],["dc.contributor.author","Lund, Lars H."],["dc.contributor.author","Pitt, Bertram"],["dc.date.accessioned","2022-01-11T14:08:13Z"],["dc.date.available","2022-01-11T14:08:13Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1002/ejhf.2386"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97970"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","1879-0844"],["dc.relation.issn","1388-9842"],["dc.title","Patiromer for the management of hyperkalaemia in patients receiving renin–angiotensin–aldosterone system inhibitors for heart failure: design and rationale of the DIAMOND trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2128"],["dc.bibliographiccitation.issue","17"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.lastpage","2136"],["dc.bibliographiccitation.volume","70"],["dc.contributor.author","Bayes-Genis, Antoni"],["dc.contributor.author","Núñez, Julio"],["dc.contributor.author","Zannad, Faiez"],["dc.contributor.author","Ferreira, João Pedro"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Cleland, John G."],["dc.contributor.author","Dickstein, Kenneth"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Lang, Chim C."],["dc.contributor.author","Ng, Leong L."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Samani, Nilesh J."],["dc.contributor.author","van Veldhuisen, Dirk J."],["dc.contributor.author","Zwinderman, Aeilko H."],["dc.contributor.author","Metra, Marco"],["dc.contributor.author","Lupón, Josep"],["dc.contributor.author","Voors, Adriaan A."],["dc.date.accessioned","2020-12-10T14:24:44Z"],["dc.date.available","2020-12-10T14:24:44Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.jacc.2017.08.057"],["dc.identifier.issn","0735-1097"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72336"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The PCSK9-LDL Receptor Axis and Outcomes in Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]