Anker, Stefan Dietmar

[["dc.bibliographiccitation.firstpage","800"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","808"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Di Tullio, Marco R."],["dc.contributor.author","Qian, Min"],["dc.contributor.author","Thompson, John L.P."],["dc.contributor.author","Labovitz, Arthur J."],["dc.contributor.author","Mann, Douglas L."],["dc.contributor.author","Sacco, Ralph L."],["dc.contributor.author","Pullicino, Patrick M."],["dc.contributor.author","Freudenberger, Ronald S."],["dc.contributor.author","Teerlink, John R."],["dc.contributor.author","Graham, Susan"],["dc.contributor.author","Lip, Gregory Y.H."],["dc.contributor.author","Levin, Bruce"],["dc.contributor.author","Mohr, Jay P."],["dc.contributor.author","Buchsbaum, Richard"],["dc.contributor.author","Estol, Conrado J."],["dc.contributor.author","Lok, Dirk J."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Homma, Shunichi"],["dc.date.accessioned","2020-12-10T14:06:09Z"],["dc.date.available","2020-12-10T14:06:09Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/ehf2.12331"],["dc.identifier.issn","2055-5822"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69796"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Left atrial volume and cardiovascular outcomes in systolic heart failure: effect of antithrombotic treatment"],["dc.title.alternative","Left atrial volume and outcome in heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","6"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","12"],["dc.bibliographiccitation.volume","205"],["dc.contributor.author","Ebner, Nicole"],["dc.contributor.author","Jankowska, Ewa A."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Lainscak, Mitja"],["dc.contributor.author","Elsner, Sebastian"],["dc.contributor.author","Sliziuk, Veronika"],["dc.contributor.author","Steinbeck, Lisa"],["dc.contributor.author","Kube, Jennifer"],["dc.contributor.author","Bekfani, Tarek"],["dc.contributor.author","Scherbakov, Nadja"],["dc.contributor.author","Valentova, Miroslava"],["dc.contributor.author","Sandek, Anja"],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","Springer, Jochen"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","von Haehling, Stephan"],["dc.date.accessioned","2020-12-10T14:24:29Z"],["dc.date.available","2020-12-10T14:24:29Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1016/j.ijcard.2015.11.178"],["dc.identifier.issn","0167-5273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72267"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The impact of iron deficiency and anaemia on exercise capacity and outcomes in patients with chronic heart failure. Results from the Studies Investigating Co-morbidities Aggravating Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","906"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","910"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Pozzoli, Massimo"],["dc.contributor.author","Gonzalez‐Costello, Jose"],["dc.contributor.author","Bayes‐Genis, Antoni"],["dc.contributor.author","Sinagra, Gianfranco"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Coats, Andrew J.S."],["dc.contributor.author","Crespo‐Leiro, Marisa G."],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Laroche, Cécile"],["dc.contributor.author","Maggioni, Aldo P."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Piepoli, Massimo F."],["dc.contributor.author","Tavazzi, Luigi"],["dc.date.accessioned","2020-12-10T14:06:19Z"],["dc.date.available","2020-12-10T14:06:19Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1002/ejhf.v22.5"],["dc.identifier.eissn","1879-0844"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69855"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prevalence of risk of thrombosis and of bleeding and antithrombotic treatment in patients with heart failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","ehy600"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","19"],["dc.contributor.author","Maack, Christoph"],["dc.contributor.author","Eschenhagen, Thomas"],["dc.contributor.author","Hamdani, Nazha"],["dc.contributor.author","Heinzel, Frank R."],["dc.contributor.author","Lyon, Alexander R."],["dc.contributor.author","Manstein, Dietmar J."],["dc.contributor.author","Metzger, Joseph"],["dc.contributor.author","Papp, Zoltán"],["dc.contributor.author","Tocchetti, Carlo G."],["dc.contributor.author","Yilmaz, M. Birhan"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Balligand, Jean-Luc"],["dc.contributor.author","Bauersachs, Johann"],["dc.contributor.author","Brutsaert, Dirk"],["dc.contributor.author","Carrier, Lucie"],["dc.contributor.author","Chlopicki, Stefan"],["dc.contributor.author","Cleland, John G."],["dc.contributor.author","de Boer, Rudolf A."],["dc.contributor.author","Dietl, Alexander"],["dc.contributor.author","Fischmeister, Rodolphe"],["dc.contributor.author","Harjola, Veli-Pekka"],["dc.contributor.author","Heymans, Stephane"],["dc.contributor.author","Hilfiker-Kleiner, Denise"],["dc.contributor.author","Holzmeister, Johannes"],["dc.contributor.author","de Keulenaer, Gilles"],["dc.contributor.author","Limongelli, Giuseppe"],["dc.contributor.author","Linke, Wolfgang A."],["dc.contributor.author","Lund, Lars H."],["dc.contributor.author","Masip, Josep"],["dc.contributor.author","Metra, Marco"],["dc.contributor.author","Mueller, Christian"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Ristić, Arsen"],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","Seferović, Petar M."],["dc.contributor.author","Skouri, Hadi"],["dc.contributor.author","Zimmermann, Wolfram H."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.date.accessioned","2019-02-20T13:50:51Z"],["dc.date.available","2019-02-20T13:50:51Z"],["dc.date.issued","2018"],["dc.description.abstract","Acute heart failure (HF) and in particular, cardiogenic shock are associated with high morbidity and mortality. A therapeutic dilemma is that the use of positive inotropic agents, such as catecholamines or phosphodiesterase-inhibitors, is associated with increased mortality. Newer drugs, such as levosimendan or omecamtiv mecarbil, target sarcomeres to improve systolic function putatively without elevating intracellular Ca2+. Although meta-analyses of smaller trials suggested that levosimendan is associated with a better outcome than dobutamine, larger comparative trials failed to confirm this observation. For omecamtiv mecarbil, Phase II clinical trials suggest a favourable haemodynamic profile in patients with acute and chronic HF, and a Phase III morbidity/mortality trial in patients with chronic HF has recently begun. Here, we review the pathophysiological basis of systolic dysfunction in patients with HF and the mechanisms through which different inotropic agents improve cardiac function. Since adenosine triphosphate and reactive oxygen species production in mitochondria are intimately linked to the processes of excitation–contraction coupling, we also discuss the impact of inotropic agents on mitochondrial bioenergetics and redox regulation. Therefore, this position paper should help identify novel targets for treatments that could not only safely improve systolic and diastolic function acutely, but potentially also myocardial structure and function over a longer-term."],["dc.identifier.doi","10.1093/eurheartj/ehy600"],["dc.identifier.pmid","30295807"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/57605"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/235"],["dc.language.iso","en"],["dc.notes.status","fcwi"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | C01: Epigenetische Kontrolle der Herzfibrose"],["dc.relation","SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien"],["dc.relation.workinggroup","RG Linke (Kardiovaskuläre Physiologie)"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","Treatments targeting inotropy"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","19"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","21"],["dc.bibliographiccitation.volume","238"],["dc.contributor.author","Palus, Sandra"],["dc.contributor.author","Springer, J. I."],["dc.contributor.author","Doehner, Wolfram"],["dc.contributor.author","von Haehling, Stephan"],["dc.contributor.author","Anker, Markus S."],["dc.contributor.author","Anker, Stefan-D."],["dc.date.accessioned","2018-11-07T10:22:26Z"],["dc.date.available","2018-11-07T10:22:26Z"],["dc.date.issued","2017"],["dc.description.abstract","Approximately 40-50% of the population over 80 years of age suffers from sarcopenia making this condition a major geriatric clinical disorder and a key challenge to healthy aging. The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenic patients are likely to have worse clinical outcomes and higher mortality compared to healthy individuals. This review will focus on animal models designed to study sarcopenia including hind-limb unloading, de-nervation, and immobilization by using casts or wire strategies, as well as using aged rodents. Currently there are no registered treatments for sarcopenia. Most sarcopenic individuals show signs of physical frailty, which leads to increases the prevalence of balance disorders, falls, fractures and pain. Therefore, is it essential to develop and use relevant animal models to further the research on sarcopenia therapy? (C) 2017 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.ijcard.2017.03.152"],["dc.identifier.isi","000402478900004"],["dc.identifier.pmid","28465116"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42272"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1874-1754"],["dc.relation.issn","0167-5273"],["dc.title","Models of sarcopenia: Short review"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","391"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","412"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Tschöpe, Carsten"],["dc.contributor.author","Boer, Rudolf A."],["dc.contributor.author","Fraser, Alan G."],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Donal, Erwan"],["dc.contributor.author","Edelmann, Frank"],["dc.contributor.author","Fu, Michael"],["dc.contributor.author","Guazzi, Marco"],["dc.contributor.author","Lam, Carolyn S.P."],["dc.contributor.author","Lancellotti, Patrizio"],["dc.contributor.author","Melenovsky, Vojtech"],["dc.contributor.author","Morris, Daniel A."],["dc.contributor.author","Nagel, Eike"],["dc.contributor.author","Pieske-Kraigher, Elisabeth"],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Solomon, Scott D."],["dc.contributor.author","Vasan, Ramachandran S."],["dc.contributor.author","Rutten, Frans H."],["dc.contributor.author","Voors, Adriaan A."],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Seferovic, Petar"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.date.accessioned","2020-12-10T14:06:19Z"],["dc.date.available","2020-12-10T14:06:19Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1093/eurheartj/ehz641"],["dc.identifier.eissn","1879-0844"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69854"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","54"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","65"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Targher, Giovanni"],["dc.contributor.author","Dauriz, Marco"],["dc.contributor.author","Laroche, Cécile"],["dc.contributor.author","Temporelli, Pier Luigi"],["dc.contributor.author","Hassanein, Mahmoud"],["dc.contributor.author","Seferovic, Petar M."],["dc.contributor.author","Drozdz, Jaroslaw"],["dc.contributor.author","Ferrari, Roberto"],["dc.contributor.author","Anker, Stephan"],["dc.contributor.author","Coats, Andrew"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Crespo-Leiro, Maria G."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Piepoli, Massimo F."],["dc.contributor.author","Maggioni, Aldo Pietro"],["dc.contributor.author","Tavazzi, Luigi"],["dc.date.accessioned","2020-12-10T14:06:22Z"],["dc.date.available","2020-12-10T14:06:22Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1002/ejhf.679"],["dc.identifier.issn","1388-9842"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/69869"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","In-hospital and 1-year mortality associated with diabetes in patients with acute heart failure: results from the ESC-HFA Heart Failure Long-Term Registry"],["dc.title.alternative","Acute heart failure and diabetes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","61"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Heart Failure Clinics"],["dc.bibliographiccitation.lastpage","69"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Valentova, Miroslava"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","von Haehling, Stephan"],["dc.date.accessioned","2020-12-10T14:24:24Z"],["dc.date.available","2020-12-10T14:24:24Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.hfc.2019.08.006"],["dc.identifier.issn","1551-7136"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72242"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Cardiac Cachexia Revisited"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1885"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","ESC Heart Failure"],["dc.bibliographiccitation.lastpage","1891"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Khan, Muhammad Shahzeb"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Butler, Javed"],["dc.date.accessioned","2021-06-01T09:41:38Z"],["dc.date.available","2021-06-01T09:41:38Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1002/ehf2.13301"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84987"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","2055-5822"],["dc.relation.issn","2055-5822"],["dc.title","Effect of Carillon Mitral Contour System on patient‐reported outcomes in functional mitral regurgitation: an individual participant data meta‐analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1956"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","New England Journal of Medicine"],["dc.bibliographiccitation.lastpage","1964"],["dc.bibliographiccitation.volume","376"],["dc.contributor.author","Packer, Milton"],["dc.contributor.author","O’Connor, Christopher"],["dc.contributor.author","McMurray, John J.V."],["dc.contributor.author","Wittes, Janet"],["dc.contributor.author","Abraham, William T."],["dc.contributor.author","Anker, Stefan D."],["dc.contributor.author","Dickstein, Kenneth"],["dc.contributor.author","Filippatos, Gerasimos"],["dc.contributor.author","Holcomb, Richard"],["dc.contributor.author","Krum, Henry"],["dc.contributor.author","Maggioni, Aldo P."],["dc.contributor.author","Mebazaa, Alexandre"],["dc.contributor.author","Peacock, W. Frank"],["dc.contributor.author","Petrie, Mark C."],["dc.contributor.author","Ponikowski, Piotr"],["dc.contributor.author","Ruschitzka, Frank"],["dc.contributor.author","van Veldhuisen, Dirk J."],["dc.contributor.author","Kowarski, Lisa S."],["dc.contributor.author","Schactman, Mark"],["dc.contributor.author","Holzmeister, Johannes"],["dc.date.accessioned","2020-12-10T18:12:31Z"],["dc.date.available","2020-12-10T18:12:31Z"],["dc.date.issued","2017"],["dc.description.abstract","BACKGROUND In patients with acute heart failure, early intervention with an intravenous vasodilator has been proposed as a therapeutic goal to reduce cardiac-wall stress and, potentially, myocardial injury, thereby favorably affecting patients' long-term prognosis. METHODS In this double-blind trial, we randomly assigned 2157 patients with acute heart failure to receive a continuous intravenous infusion of either ularitide at a dose of 15 ng per kilogram of body weight per minute or matching placebo for 48 hours, in addition to accepted therapy. Treatment was initiated a median of 6 hours after the initial clinical evaluation. The coprimary outcomes were death from cardiovascular causes during a median follow-up of 15 months and a hierarchical composite end point that evaluated the initial 48-hour clinical course. RESULTS Death from cardiovascular causes occurred in 236 patients in the ularitide group and 225 patients in the placebo group (21.7% vs. 21.0%; hazard ratio, 1.03; 96% confidence interval, 0.85 to 1.25; P=0.75). In the intention-to-treat analysis, there was no significant between-group difference with respect to the hierarchical composite outcome. The ularitide group had greater reductions in systolic blood pressure and in levels of N-terminal pro-brain natriuretic peptide than the placebo group. However, changes in cardiac troponin T levels during the infusion did not differ between the two groups in the 55% of patients with paired data. CONCLUSIONS In patients with acute heart failure, ularitide exerted favorable physiological effects (without affecting cardiac troponin levels), but short-term treatment did not affect a clinical composite end point or reduce long-term cardiovascular mortality. (Funded by Cardiorentis; TRUE-AHF ClinicalTrials.gov number, NCT01661634.)"],["dc.identifier.doi","10.1056/NEJMoa1601895"],["dc.identifier.eissn","1533-4406"],["dc.identifier.isi","000401407500009"],["dc.identifier.issn","0028-4793"],["dc.identifier.pmid","28402745"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74406"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Massachusetts Medical Soc"],["dc.relation.issn","1533-4406"],["dc.relation.issn","0028-4793"],["dc.title","Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]