Czerny, Claus-Peter

[["dc.bibliographiccitation.firstpage","1653"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Dairy Science"],["dc.bibliographiccitation.lastpage","1660"],["dc.bibliographiccitation.volume","96"],["dc.contributor.author","Pilla, Rachel"],["dc.contributor.author","Malvisi, M."],["dc.contributor.author","Snel, G. G. M."],["dc.contributor.author","Schwarz, Daniel"],["dc.contributor.author","Koenig, S."],["dc.contributor.author","Czerny, C-P"],["dc.contributor.author","Piccinini, Renata"],["dc.date.accessioned","2018-11-07T09:27:48Z"],["dc.date.available","2018-11-07T09:27:48Z"],["dc.date.issued","2013"],["dc.description.abstract","Changes in relative cell proportions occurring in diseased mammary glands of dairy cows can be determined using differential cell count (DCC). The present study was carried out in 2 consecutive trials, with 2 goals: (a) to test the consistency of DCC results on subsequent days, and (b) to establish an effective cutoff value for the diagnosis of mastitis. In the first trial, quarter milk and blood samples were taken from 8 healthy cows for 5 consecutive days. Milk samples were tested by somatic cell count (SCC) and bacteriological analysis, and DCC was performed on blood and milk samples by flow cytometer. In the second trial, 16 animals were randomly selected from a different herd and quarter milk samples taken on 3 consecutive milkings. All samples were cyto-bacteriologically analyzed and DCC was performed on the second sampling. In the first trial, mean SCC was 77,770 cells/mL and 4 samples were bacteriologically positive. No fixed or random effect had a significant influence on percentages of individual cell populations or ratios in blood or milk. A cutoff value of 0.495 for logarithmic polymorphonuclear neutrophilic leukocyte:lymphocyte ratio was established. Mean SCC of milk samples collected in the second trial was 543,230 cells/mL, and infection was detected in 53.1% of quarters, mostly caused by Staphylococcus aureus. When the cutoff value was applied to the data along with SCC, sensitivity and specificity of the diagnostic method were 97.3 and 92.3%, respectively."],["dc.identifier.doi","10.3168/jds.2012-6298"],["dc.identifier.isi","000315061700031"],["dc.identifier.pmid","23332851"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30621"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0022-0302"],["dc.title","Differential cell count as an alternative method to diagnose dairy cow mastitis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","5033"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Journal of Dairy Science"],["dc.bibliographiccitation.lastpage","5044"],["dc.bibliographiccitation.volume","94"],["dc.contributor.author","Schwarz, Daniel"],["dc.contributor.author","Diesterbeck, Ulrike S"],["dc.contributor.author","Koenig, S."],["dc.contributor.author","Bruegemann, Kerstin"],["dc.contributor.author","Schlez, Karen"],["dc.contributor.author","Zschoeck, Michael"],["dc.contributor.author","Wolter, Wilfried"],["dc.contributor.author","Czerny, C-P"],["dc.date.accessioned","2018-11-07T08:51:19Z"],["dc.date.available","2018-11-07T08:51:19Z"],["dc.date.issued","2011"],["dc.description.abstract","Somatic cell counts (SCC) are generally used as an indicator of udder health. In Germany; a cutoff value of 100,000 cells/mL is currently used to differentiate between healthy and diseased mammary glands. In addition to SCC, differential cell counts (DCC) can be applied for a more detailed evaluation of the udder health status. The aim of this study was to differentiate immune cells in milk of udder quarters classified as healthy based on SCC values of <100,000 cells/mL. Twenty cows were selected and 65 healthy udder quarters were compared with a control group of 15 diseased udder quarters (SCC > 100,000 cells/mL). Cells were isolated from milk of all quarters to measure simultaneously percentages of lymphocytes, macrophages, and polymorphonuclear neutrophilic leukocytes (PMNL) by flow cytometric analysis. The bacteriological status of all 80 quarters was also determined. Differential cell count patterns of milk samples (n = 15) with extreme low SCC values of <= 6,250 cells/mL revealed high lymphocyte proportions of up to 88%. Milk cell populations in samples (n = 42) with SCC values from >6,250 to <= 25,000 cells/mL were also dominated by lymphocytes, whereas DCC patterns of 6 out of 41 milk samples with SCC values from >= 9,000 to <= 46,000 cells/mL indicated already inflammatory reactions based on the predominance of PMNL (56-75%). In 13 of 15 milk samples of the diseased udder quarters (SCC >100,000 cells/mL), PMNL were categorically found as dominant cell population with proportions of >= 49%. Macrophages were the second predominant cell population in almost all samples tested in relation to lymphocytes and PMNL. Farther analysis of the data demonstrated significant differences of the cellular components between udder quarters infected by major pathogens (e.g., Staphylococcus aureus; n = 5) and culture-negative udder quarters (n = 56). Even the percentages of immune cells in milk from quarters infected by minor pathogens (e.g., coagulase-negative staphylococci; n = 19) differed significantly from those in milk of culture-negative quarters. Our flow cytometric analysis of immune cells in milk of udder quarters classified as healthy by SCC <100,000 cells/mL revealed inflammatory reactions based on DCC."],["dc.identifier.doi","10.3168/jds.2011-4348"],["dc.identifier.isi","000295192600028"],["dc.identifier.pmid","21943754"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21906"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0022-0302"],["dc.title","Flow cytometric differential cell counts in milk for the evaluation of inflammatory reactions in clinically healthy and subclinically infected bovine mammary glands"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","212"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Veterinary Pathology"],["dc.bibliographiccitation.lastpage","218"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Mätz-Rensing, K."],["dc.contributor.author","Ellerbrok, H."],["dc.contributor.author","Ehlers, B."],["dc.contributor.author","Pauli, G."],["dc.contributor.author","Floto, A."],["dc.contributor.author","Alex, M."],["dc.contributor.author","Czerny, C.-P."],["dc.contributor.author","Kaup, F.-J."],["dc.date.accessioned","2022-10-06T13:26:19Z"],["dc.date.available","2022-10-06T13:26:19Z"],["dc.date.issued","2016"],["dc.description.abstract","An epizootic infection was observed in a colony of 80 New World monkeys consisting of various species including a group of marmosets and Saguinus species. During the summer and autumn of 2002, 30 animals died of unknown diseases. Six animals were sent to the German Primate Center for investigation of the cause of death. A complete pathologic and histologic investigation was carried out. The animals exhibited erosive-ulcerative lesions of the oral mucous membranes. Advanced stages of the disease were characterised by hemorrhagic lesions on the skin distributed randomly over the body, but principally on the face, scrotal region, soles, and palms. Electron microscopy revealed virus particles with orthopox-like morphology within intracytoplasmic inclusions in epithelial cells. The DNA samples from various tissues were analyzed by use of a set of orthopox virus-specific, real-time polymerase chain reaction assays. Amplification products were sequenced to define the virus more precisely. Sequencing confirmed the presence of an orthopox virus. Sequence data indicated that all six animals were infected with the same virus. Propagation of the virus on Vero cells resulted in a rapidly progressive cytopathogenic effect. Preliminary phylogenetic analyses of two genes revealed closest homology to cowpox viruses. The origin of this poxvirus outbreak remains unexplained, and the strain and genus of the virus need to be determined in detail."],["dc.identifier.doi","10.1354/vp.43-2-212"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115058"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1544-2217"],["dc.relation.issn","0300-9858"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Fatal Poxvirus Outbreak in a Colony of New World Monkeys"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","211"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Medical Primatology"],["dc.bibliographiccitation.lastpage","217"],["dc.bibliographiccitation.volume","46"],["dc.contributor.author","Fechner, Kim"],["dc.contributor.author","Mätz-Rensing, Kerstin"],["dc.contributor.author","Lampe, Karen"],["dc.contributor.author","Kaup, Franz-Josef"],["dc.contributor.author","Czerny, Claus-Peter"],["dc.contributor.author","Schäfer, Jenny"],["dc.date.accessioned","2020-12-10T18:29:00Z"],["dc.date.available","2020-12-10T18:29:00Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1111/jmp.12270"],["dc.identifier.issn","0047-2565"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76490"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.issn","0047-2565"],["dc.title","Detection of Mycobacterium avium subsp. paratuberculosis in non-human primates"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","162"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","DEUTSCHE TIERARZTLICHE WOCHENSCHRIFT"],["dc.bibliographiccitation.lastpage","166"],["dc.bibliographiccitation.volume","115"],["dc.contributor.author","Moorkamp, L."],["dc.contributor.author","Beineke, Andreas"],["dc.contributor.author","Kaim, U."],["dc.contributor.author","Diesterbeck, Ulrike S"],["dc.contributor.author","Urstadt, S."],["dc.contributor.author","Czerny, C.-P"],["dc.contributor.author","Rueberg, H."],["dc.contributor.author","Grosse, Beilage E."],["dc.date.accessioned","2018-11-07T11:16:25Z"],["dc.date.available","2018-11-07T11:16:25Z"],["dc.date.issued","2008"],["dc.description.abstract","Swinepox virus infection results in an acute, mild or subclinical course and is characterised by typical poxvirus skin lesions in affected pigs. Additionally, sporadic vertical swinepox virus transmission leads to congenital generalised infection and subsequent abortion or stillbirth. The present report describes the occurrence of epidermal efflorescences in two piglets after intrauterine natural suipoxvirus infection. No clinical abnormalities of the gilt and littermates as well as in other pigs from this herd were present. One of the affected piglets was stillborn and submitted for necropsy, the other animal was alive at birth, but died 3 days later. Histologically, a proliferative to ulcerative dermatitis with epithelial ballooning degeneration and characteristic intracytoplasmatic inclusion bodies was observed. The pathomorphological and histopathological suspected diagnosis of a poxvirus infection was confirmed by electron microscopy. Furthermore, the agent was identified as suipoxvirus by polymerase chain reaction. As demonstrated here, obvious skin lesions in suipoxvirus infection leads to a suspected diagnosis in newborn piglets on macroscopic examination. However, further post mortem examinations, including electron microscopy as well as molecular techniques are essential for the identification of the aetiology and the exclusion of differential diagnoses. Because the disease only affected two pigs there was only a small economic loss. A valid diagnostic plays an important role in advising farmers and for herd health monitoring."],["dc.identifier.doi","10.2377/0341-6593-115-162"],["dc.identifier.isi","000255153100006"],["dc.identifier.pmid","18500151"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54586"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","M H Schaper Gmbh Co Kg"],["dc.relation.issn","0341-6593"],["dc.title","Swinepox - skin disease with sporadic occurrence"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","31"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Zoonoses and Public Health"],["dc.bibliographiccitation.lastpage","37"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Schulze, Catharina"],["dc.contributor.author","Alex, M."],["dc.contributor.author","Schirrmeier, H."],["dc.contributor.author","Hlinak, A."],["dc.contributor.author","Engelhardt, Antje"],["dc.contributor.author","Koschinski, B."],["dc.contributor.author","Beyreiss, B."],["dc.contributor.author","Hoffmann, M."],["dc.contributor.author","Czerny, C.-P."],["dc.date.accessioned","2018-11-07T11:07:49Z"],["dc.date.available","2018-11-07T11:07:49Z"],["dc.date.issued","2007"],["dc.description.abstract","A 4-month-old female domestic shorthair cat was infected by a virus of the Poxvirus family. The animal developed a severe pneumonia and generalized ulcerating lesions of the skin. Histologically, typical eosinophilic intracytoplasmic inclusion bodies indicative of an Orthopoxvirus (OPV) infection were present. The lung showed grey-white to haemorrhagic nodular lesions with a central zone of complete necrosis of alveolar and bronchial tissue. Electron microscopy from skin and lung nodules revealed typical square-shaped OPV particles. Cultivation of the virus on chorio-allantoic membranes of embryonated chicken eggs resulted in haemorrhagic plaques. Restriction enzyme analysis, PCR and sequencing of the D8L gene identified the OPV isolate as a typical Cowpox virus. It was transmitted by the cat to a human contact person who developed a local nodular dermatitis at the inoculation site in association with signs of general infection and had an increase of OPV-specific neutralizing antibodies in paired serum samples."],["dc.identifier.doi","10.1111/j.1863-2378.2007.00995.x"],["dc.identifier.isi","000245472400006"],["dc.identifier.pmid","17359444"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52663"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","1863-1959"],["dc.title","Generalized fatal Cowpox virus infection in a cat with transmission to a human contact case"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1007"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Microorganisms"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Okuni, Julius Boniface"],["dc.contributor.author","Hansen, Sören"],["dc.contributor.author","Eltom, Kamal H."],["dc.contributor.author","Eltayeb, ElSagad"],["dc.contributor.author","Amanzada, Ahmad"],["dc.contributor.author","Omega, Joseph Amesa"],["dc.contributor.author","Czerny, Claus Peter"],["dc.contributor.author","Abd El Wahed, Ahmed"],["dc.contributor.author","Ojok, Lonzy"],["dc.date.accessioned","2021-04-14T08:25:03Z"],["dc.date.available","2021-04-14T08:25:03Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3390/microorganisms8071007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81506"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2076-2607"],["dc.title","Paratuberculosis: A Potential Zoonosis and a Neglected Disease in Africa"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","303"],["dc.bibliographiccitation.issue","7-8"],["dc.bibliographiccitation.journal","BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT"],["dc.bibliographiccitation.lastpage","312"],["dc.bibliographiccitation.volume","124"],["dc.contributor.author","Voelkel, Inger"],["dc.contributor.author","Czerny, Claus-Peter"],["dc.date.accessioned","2018-11-07T08:54:39Z"],["dc.date.available","2018-11-07T08:54:39Z"],["dc.date.issued","2011"],["dc.description.abstract","During the last years, bacteriophages have been used as valuable tool in microbiological diagnostics and basic research. Even though the potential of bacteriophages for fighting bacterial pathogens is known for a long time, the phage therapy is not used in daily routine worldwide. Due to the continuing spread of bacterial resistance to antimicrobials and an increasing awareness of the necessity to protect consumers' health, the phage therapy meanwhile has become a subject of major interest in veterinary medicine, too. This article is meant to present fields of application for phage therapy as well as current trends of development in the field of livestock animals."],["dc.identifier.doi","10.2376/0005-9366-124-303"],["dc.identifier.isi","000292802800006"],["dc.identifier.pmid","21848038"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22718"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Schluetersche Verlagsgesellschaft Mbh & Co Kg"],["dc.relation.issn","0005-9366"],["dc.title","Phage therapy in the fields of veterinary medicine: an overview"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","333"],["dc.bibliographiccitation.issue","7-8"],["dc.bibliographiccitation.journal","BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT"],["dc.bibliographiccitation.lastpage","341"],["dc.bibliographiccitation.volume","126"],["dc.contributor.author","Riedl, Antonia M."],["dc.contributor.author","Voelker, Inger"],["dc.contributor.author","Schlindwein, Bernhard"],["dc.contributor.author","Czerny, Claus-Peter"],["dc.date.accessioned","2018-11-07T09:22:59Z"],["dc.date.available","2018-11-07T09:22:59Z"],["dc.date.issued","2013"],["dc.description.abstract","Considering continuously increasing forage costs, the feed conversion rate has a major impact on the economic efficiency in hog fattening. The influence of hygienic management strategies on animal health and feed efficiency was evaluated by an online-study comprising animal health management data of 202 German pig fatteners. Data analysis included a simple comparison of averages, a linear regression analysis, and a cluster analysis. Due to geographical distribution and size of premises, the random sample was not representative but yielded in significant results. The total impact of hygienic management on feed conversion was calculated to be 23.9 %. Professional performance of rodent control (beta = 0.357; p <= 0.001), efficient insect larvae control (beta = 0.276; p = 0.008), requiring visitors to wear protective gear (beta = 0.261; p = 0.009), and immediately performed cleaning and disinfection of emptied pens (beta = 0.247; p = 0.017) were top-ranking variables. Furthermore, a significantly better feed efficiency was observed in companies reporting stables in a good state of repair or performing further preventive strategies to control animal health on herd-level (storage of fodder retain samples, health screening based on blood and faecal samples, cross-section to verify unclear death cases). For pig fatteners the benefit resulting from improved feed conversion ranged from Euro 1.15 to and Euro 2.53 per pig. Likewise optimized growth performance as a result of improved hygienic management could partly compensate increasing feed costs. The results of this online-study reveal the need to establish reliable HACCP systems on farm level."],["dc.identifier.doi","10.2376/0005-9366-126-333"],["dc.identifier.isi","000321679400009"],["dc.identifier.pmid","23901589"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29473"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Schluetersche Verlagsgesellschaft Mbh & Co Kg"],["dc.relation.issn","0005-9366"],["dc.title","Improving the feed conversion rate in the pig fattening industry by optimising hygienic management"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.volume","297"],["dc.contributor.author","Voelkel, Inger"],["dc.contributor.author","Urstadt, S."],["dc.contributor.author","Karapetyan, A."],["dc.contributor.author","Thebille, S."],["dc.contributor.author","Niederhausen, M."],["dc.contributor.author","Schmelz, F."],["dc.contributor.author","Czerny, C.-P."],["dc.date.accessioned","2018-11-07T10:59:03Z"],["dc.date.available","2018-11-07T10:59:03Z"],["dc.date.issued","2007"],["dc.format.extent","14"],["dc.identifier.isi","000250104800029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50605"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.conference","59th Annual Meeting of the Deutschen-Gesellschaft-fur-Hygiene-und-Mikrobiologie"],["dc.relation.eventlocation","Gottingen, GERMANY"],["dc.relation.issn","1438-4221"],["dc.title","Development of semi-nested and quantitative real time pool PCR methods for the detection of Mycobacterium avium subsp paratuberculosis in seropositive and seronegative dairy cows"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]