Happe, Svenja

[["dc.bibliographiccitation.firstpage","1037"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of Neurology"],["dc.bibliographiccitation.lastpage","1043"],["dc.bibliographiccitation.volume","254"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Baier, Paul Christian"],["dc.contributor.author","Helmschmied, Kathrin"],["dc.contributor.author","Meller, Johannes"],["dc.contributor.author","Tatsch, Klaus"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:00:13Z"],["dc.date.available","2018-11-07T11:00:13Z"],["dc.date.issued","2007"],["dc.description.abstract","Many patients with Parkinson's disease (PD) report daytime sleepiness. Its etiology, however, is still not fully understood. The aim of this study was to examine if the amount of nigrostriatal dopaminergic degeneration is associated with subjective daytime sleepiness in patients with PD. We investigated 21 patients with PD clinically and by means of [I-123] FP-CIT-SPECT (DaTSCAN(R)). Each patient filled in the Epworth sleepiness scale (ESS), the Parkinson's Disease Sleep Scale (PDSS), and the self-rating depression scale according to Zung (SDS) to assess sleepiness, sleep quality, and depressive symptoms. The mean specific dopamine transporter binding in the 21 PD patients (60.8 +/- 10.4 years, nine females, median Hoehn and Yahr stage 2.0) was decreased. Nine patients were in Hoehn and Yahr stage 1 (58.7 +/- 6.6 years, four females; ESS score 7.4 +/- 4.5; PDSS score 105.1 +/- 30.9), the other 12 patients were in Hoehn and Yahr stage 2 (62.4 +/- 12.6 years, five females; ESS score 6.7 +/- 4.7, PDSS score 97.1 +/- 25.6). Age, gender, ESS, and PDSS scores were not significantly different in both groups. However, ESS scores showed an inverse correlation with mean DAT binding in the striatum (r = -0.627, p = 0.03), the caudate nucleus (r = -0.708, p = 0.01), and the putamen (r = -0.599, p = 0.04) in patients with Hoehn and Yahr stage 2. There was no correlation of the ESS score with age, disease duration, UPDRS motor score, PDSS score, or depression score. Subjective daytime sleepiness seems to be associated with dopaminergic nigrostriatal degeneration in early PD."],["dc.identifier.doi","10.1007/s00415-006-0483-6"],["dc.identifier.isi","000249205900009"],["dc.identifier.pmid","17351722"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50880"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Dr Dietrich Steinkopff Verlag"],["dc.relation.issn","0340-5354"],["dc.title","Association of daytime sleepiness with nigrostriatal dopaminergic degeneration in early Parkinson's disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S495"],["dc.bibliographiccitation.journal","Movement Disorders"],["dc.bibliographiccitation.lastpage","S504"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Trenkwalder, Claudia"],["dc.contributor.author","Kohnen, Ralf"],["dc.contributor.author","Allen, Richard P."],["dc.contributor.author","Benes, Heike"],["dc.contributor.author","Ferini-Strambi, Luigi"],["dc.contributor.author","Garcia-Borreguero, Diego"],["dc.contributor.author","Hadjigeorgiou, Georgios M."],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Hoegl, Birgit"],["dc.contributor.author","Hornyak, Magdolna"],["dc.contributor.author","Klein, Christine"],["dc.contributor.author","Nass, Alexander"],["dc.contributor.author","Montagna, Pasquale"],["dc.contributor.author","Oertel, Wolfgang Hermann"],["dc.contributor.author","O'Keeffe, Shaun"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Poewe, Werner"],["dc.contributor.author","Provini, Federica"],["dc.contributor.author","Pramstaller, Peter P."],["dc.contributor.author","Sieminski, Mariusz"],["dc.contributor.author","Sonka, Karel"],["dc.contributor.author","Stiasny-Kolster, Karin"],["dc.contributor.author","de Weerd, A. L."],["dc.contributor.author","Wetter, Thomas C."],["dc.contributor.author","Winkelmann, Juliane"],["dc.contributor.author","Zucconi, Marco"],["dc.date.accessioned","2018-11-07T11:07:07Z"],["dc.date.available","2018-11-07T11:07:07Z"],["dc.date.issued","2007"],["dc.description.abstract","The European Restless Leas Syndrome (RLS) Study Group (EURLSSG) is an association of European RLS experts who are actively involved in RLS research. A major aim of the Study Group is the development and continuous improvement of standards for diagnosis and treatment of RLS. Several members developed study designs and evaluation methods in investigator-initiated trials early in the 1990s, and all members have since contributed to many pivotal and nonpivotal drug trials for the treatment of RLS. The recommendations on clinical investigations of pharmacological treatment of RLS patients summarize the group's expertise and knowledge acquired through clinical trials. The recommendations primarily address how to plan and conduct confirmatory, randomized clinical studies in patients with idiopathic RLS. Advice is presented for the diagnosis of RLS and clinical and polysomnographic inclusion and exclusion criteria. Primary and secondary endpoints for an evaluation of efficacy are based on a critical description of validated methods for both short- and long-term trials, also in special populations (children, pregnant women, elderly patients). The recommendations include the assessment of augmentation. Finally, general issues including the evaluation of safety and tolerability, as well as specific neurological and cardiovascular risks and sleep attacks/daytime somnolence, are discussed. The aim of these recommendations is to support research groups or pharmaceutical companies in the design of optimized study protocols. (C) 2007 Movement Disorder Society."],["dc.identifier.doi","10.1002/mds.21538"],["dc.identifier.isi","000251605200015"],["dc.identifier.pmid","17530666"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52479"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","Scientific Symposium and Augmentation Workshop on Restless Leg Syndrome"],["dc.relation.eventlocation","Max Planck Inst Phys Complex Syst, Munich, GERMANY"],["dc.relation.issn","1531-8257"],["dc.relation.issn","0885-3185"],["dc.title","Clinical trials in restless legs syndrome - Recommendations of the European RLS study group (EURLSSG)"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1511"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Movement Disorders"],["dc.bibliographiccitation.lastpage","1515"],["dc.bibliographiccitation.volume","19"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Tings, T."],["dc.contributor.author","Helmschmied, Kathrin"],["dc.contributor.author","Neubert, K."],["dc.contributor.author","Wuttke, Wolfgang"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Trenkwalder, Claudia"],["dc.date.accessioned","2018-11-07T10:43:34Z"],["dc.date.available","2018-11-07T10:43:34Z"],["dc.date.issued","2004"],["dc.description.abstract","Challenge with low-dose apomorphine causes a significant rise in growth hormone (GH) in patients with Parkinson's disease (PD) compared to controls and patients with multiple system atrophy (MSA) who have not previously received dopaminergic treatment. To date, it has not been demonstrated whether an apomorphine-induced rise in GH can still be detected in PD patients who are currently treated with levodopa. We investigated whether an ongoing treatment with levodopa influences the GH response to subcutaneously applied low-dose apomorphine in PD patients. We studied 44 patients with idiopathic PD using the low-dose apomorphine test. Twenty-three patients were under treatment with levodopa and 21 patients were without any dopaminergic therapy. GH and cortisol levels were analyzed at time of injection and 45 minutes and 60 minutes after subcutaneous apomorphine injection. Forty-five minutes after apomorphine injection, there was no significant difference between the mean rise in plasma GH in untreated PD patients compared with levodopa-treated patients (P = 0.235). There was no increase of cortisol levels in each treatment group. Age, sex, duration, and severity of the disease did not show a covariate effect with GH levels. A small group of PD patients (n = 8) treated with dopamine agonists and a small group of patients with MSA (n = 5) as well as patients with vascular parkinsonism (n = 5) did not show any increase of GH. Our data suggest that the apomorphine-induced rise in GH does not depend on previous levodopa treatment in PD patients but, as expected, is blocked by dopamine agonists and is not present in patients with other than idiopathic parkinsonian syndrome. Thus, the low-dose apomorphine test may also be a useful biological marker in the early differential diagnosis of PD patients who have already received levodopa treatment. (C) 2004 Movement Disorder Society."],["dc.identifier.doi","10.1002/mds.20244"],["dc.identifier.isi","000225774100023"],["dc.identifier.pmid","15390061"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47084"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-liss"],["dc.relation.issn","0885-3185"],["dc.title","Levodopa treatment does not affect low-dose apomorphine test in patients with Parkinson's disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","762"],["dc.bibliographiccitation.journal","Brain"],["dc.bibliographiccitation.lastpage","770"],["dc.bibliographiccitation.volume","133"],["dc.contributor.author","Bachmann, Cornelius G."],["dc.contributor.author","Rolke, Roman"],["dc.contributor.author","Scheidt, Uta"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Pavlakovic, Goran"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Treede, Rolf-Detlef"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:45:14Z"],["dc.date.available","2018-11-07T08:45:14Z"],["dc.date.issued","2010"],["dc.description.abstract","This study aimed to assess thermal and mechanical perception and pain thresholds in primary idiopathic restless legs syndrome and secondary restless legs syndrome associated with small fibre neuropathy. Twenty-one patients (age: 53.4 +/- 8.4, n = 3, male) with primary restless legs syndrome and 13 patients (age: 63.0 +/- 8.2, n = 1, male) with secondary restless legs syndrome associated with small fibre neuropathy were compared with 20 healthy subjects (age: 58.0 +/- 7.0; n = 2, male). Differential diagnosis of secondary restless legs syndrome associated with small fibre neuropathy was based on clinical symptoms and confirmed with skin biopsies in all patients. A comprehensive quantitative sensory testing protocol encompassing thermal and mechanical detection and pain thresholds, as devised by the German Research Network on Neuropathic Pain, was performed on the clinically more affected foot between 2 pm and 1 am when restless legs syndrome symptoms were present in all patients. Patients with primary restless legs syndrome showed hyperalgesia to blunt pressure (P < 0.001), pinprick (P < 0.001) and vibratory hyperaesthesia (P < 0.001). Patients with secondary restless legs syndrome associated with small fibre neuropathy showed thermal hypoaesthesia to cold (A delta-fibre mediated) and warm (C-fibre mediated) (all P < 0.001) and hyperalgesia to pinprick (P < 0.001). Static mechanical hyperalgesia in primary and secondary restless legs syndrome is consistent with the concept of central disinhibition of nociceptive pathways, which might be induced by conditioning afferent input from damaged small fibre neurons in secondary restless legs syndrome."],["dc.identifier.doi","10.1093/brain/awq026"],["dc.identifier.isi","000276046000012"],["dc.identifier.pmid","20194142"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6232"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20388"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","0006-8950"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Thermal hypoaesthesia differentiates secondary restless legs syndrome associated with small fibre neuropathy from primary restless legs syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.volume","66"],["dc.contributor.author","Lang, N."],["dc.contributor.author","Baudewig, Juergen"],["dc.contributor.author","Kallenberg, Kai"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:04:50Z"],["dc.date.available","2018-11-07T10:04:50Z"],["dc.date.issued","2006"],["dc.format.extent","916"],["dc.identifier.doi","10.1212/01.wnl.0000203113.12324.57"],["dc.identifier.isi","000236292300026"],["dc.identifier.pmid","16567712"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38780"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0028-3878"],["dc.title","Transient prosopagnosia after ischemic stroke"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","188"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","AKTUELLE NEUROLOGIE"],["dc.bibliographiccitation.lastpage","196"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:49:03Z"],["dc.date.available","2018-11-07T10:49:03Z"],["dc.date.issued","2004"],["dc.description.abstract","The incidence of steep disorders increases with age, about 20% of the women and 10% of the men > 75 years of age suffer from sleep disorders. Sleep has an important impact on subjective well-being and quality of life, sleep disorders are associated with medical diseases and earlier death. As a consequence of frequent sleep disorders, the prescription rate of hypnotics increases with age and lies between 10% and 15% in the elderly. Numerous factors may disturb sleep in the elderly. Frequent somatic and psychiatric diseases in the older population can significantly be associated with sleep disorders, a concomitant depression is known to be the main predictor. Consequences of sleep disorders in the elderly are manifold. The present paper gives an overview of the most frequent reasons of sleep disorders in older age, their influence on life expectancy, general health, and quality of life as well as possible treatment strategies."],["dc.identifier.doi","10.1055/s-2003-814932"],["dc.identifier.isi","000221530000004"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48340"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","0302-4350"],["dc.title","Sleep disorders in the elderly"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","122"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Pain Medicine"],["dc.bibliographiccitation.lastpage","132"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Csifcsak, Gabor"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Hillers, Ferdinand"],["dc.contributor.author","Levold, Maik"],["dc.contributor.author","Bachmann, Cornelius G."],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Ellrich, Jens"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:35:19Z"],["dc.date.available","2018-11-07T08:35:19Z"],["dc.date.issued","2009"],["dc.description.abstract","Invasive stimulation of the motor cortex has been used for years to alleviate chronic intractable pain in humans. In our study, we have investigated the effect of transcranial direct current stimulation (tDCS), a noninvasive stimulation method, for manipulating the excitability of cortical motor areas on laser evoked potentials (LEP) and acute pain perception. The amplitude of the N1, N2, and P2 LEP components of 10 healthy volunteers were evaluated prior to and following anodal, cathodal, and sham stimulation of the primary motor cortex. In a separate experiment subjective, pain rating scores of 16 healthy subjects in two perceptual categories (warm sensation, mild pain) were also analyzed. Cathodal tDCS significantly reduced the amplitude of N2 and P2 components compared with anodal or sham stimulation. However, neither of the tDCS types modified significantly the laser energy values necessary to induce moderate pain. In a separate experiment, cathodal stimulation significantly diminished mild pain sensation only when laser-stimulating the hand contralateral to the side of tDCS, while anodal stimulation modified warm sensation. The possible underlying mechanisms of our findings in view of recent neuroimaging studies are discussed. To our knowledge this study is the first to demonstrate the mild antinociceptive effect of tDCS over the primary motor cortex in healthy volunteers."],["dc.identifier.doi","10.1111/j.1526-4637.2008.00508.x"],["dc.identifier.isi","000262901400016"],["dc.identifier.pmid","18823388"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18034"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.relation.issn","1526-2375"],["dc.title","Modulatory Effects of Transcranial Direct Current Stimulation on Laser-Evoked Potentials"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","122"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neuroscience Letters"],["dc.bibliographiccitation.lastpage","125"],["dc.bibliographiccitation.volume","489"],["dc.contributor.author","Bachmann, Cornelius G."],["dc.contributor.author","Nitsche, M. A."],["dc.contributor.author","Pfingsten, M."],["dc.contributor.author","Gersdorff, Nikolaus"],["dc.contributor.author","Harder, C."],["dc.contributor.author","Baier, Paul Christian"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Treede, Rolf-Detlef"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Happe, Svenja"],["dc.date.accessioned","2018-11-07T08:59:19Z"],["dc.date.available","2018-11-07T08:59:19Z"],["dc.date.issued","2011"],["dc.description.abstract","Rapid skin heating by infrared lasers can be used to investigate the integrity of the nociceptive system by activating A-delta and C fibers. The aim of our study was to analyze if healthy humans exhibit any clinically relevant diurnal variations in their heat pain sensitivity. Circadian A-delta fiber function was analyzed by studying N2 and P2 components of laser-evoked potentials (LEP) and pain thresholds evoked by laser stimulation of the foot every 2 h from 8 a.m. to 10 p.m. in 15 healthy subjects. Heat stimuli were generated by an infrared Tm-YAG laser and were delivered to an area of 4 cm x 4.5 cm on the dorsum of the right or left foot in 3 runs of incremental and decremental intensities. After each stimulus subjects were asked to classify the intensity of pain with a numeric rating scale (NRS). LEPs were recorded with fixed stimulus intensities that were 1.5x of the pain threshold. Data were collected with the SynAmps System (Neuroscan, El Paso, USA) and averaged across 35-40 trials. Laser-induced heat pain thresholds and circadian latencies of LEP did not significantly vary during the day. Our results correspond with previous studies that did not detect any consistent significant diurnal variations in perception of heat pain perception using contact thermodes. The intensity of pain perception did not demonstrate any correlation with mood or sleep parameters as measured with the Beck Depression Inventory (BDI), the subjective sleep scales Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). (C) 2010 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.neulet.2010.11.080"],["dc.identifier.isi","000287123000012"],["dc.identifier.pmid","21145371"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23861"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","1872-7972"],["dc.relation.issn","0304-3940"],["dc.title","Diurnal time course of heat pain perception in healthy humans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2603"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Neurophysiology"],["dc.bibliographiccitation.lastpage","2614"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Nitsche, Michael A."],["dc.contributor.author","Jakoubkova, Michaela"],["dc.contributor.author","Thirugnanasambandam, Nivethida"],["dc.contributor.author","Schmalfuss, Leonie"],["dc.contributor.author","Hullemann, Sandra"],["dc.contributor.author","Sonka, Karel"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Trenkwalder, Claudia"],["dc.contributor.author","Happe, Svenja"],["dc.date.accessioned","2018-11-07T08:37:38Z"],["dc.date.available","2018-11-07T08:37:38Z"],["dc.date.issued","2010"],["dc.description.abstract","Nitsche MA, Jakoubkova M, Thirugnanasambandam N, Schmalfuss L, Hullemann S, Sonka K, Paulus W, Trenkwalder C, Happe S. Contribution of the premotor cortex to consolidation of motor sequence learning in humans during sleep. J Neurophysiol 104: 2603-2614, 2010. First published September 15, 2010; doi:10.1152/jn.00611.2010. Motor learning and memory consolidation require the contribution of different cortices. For motor sequence learning, the primary motor cortex is involved primarily in its acquisition. Premotor areas might be important for consolidation. In accordance, modulation of cortical excitability via transcranial DC stimulation (tDCS) during learning affects performance when applied to the primary motor cortex, but not premotor cortex. We aimed to explore whether premotor tDCS influences task performance during motor memory consolidation. The impact of excitability-enhancing, -diminishing, or placebo premotor tDCS during rapid eye movement (REM) sleep on recall in the serial reaction time task (SRTT) was explored in healthy humans. The motor task was learned in the evening. Recall was performed immediately after tDCS or the following morning. In two separate control experiments, excitability-enhancing premotor tDCS was performed 4 h after task learning during daytime or immediately before conduction of a simple reaction time task. Excitability-enhancing tDCS performed during REM sleep increased recall of the learned movement sequences, when tested immediately after stimulation. REM density was enhanced by excitability-increasing tDCS and reduced by inhibitory tDCS, but did not correlate with task performance. In the control experiments, tDCS did not improve performance. We conclude that the premotor cortex is involved in motor memory consolidation during REM sleep."],["dc.identifier.doi","10.1152/jn.00611.2010"],["dc.identifier.isi","000285392000027"],["dc.identifier.pmid","20844115"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18584"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Physiological Soc"],["dc.relation.issn","0022-3077"],["dc.title","Contribution of the Premotor Cortex to Consolidation of Motor Sequence Learning in Humans During Sleep"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e168"],["dc.bibliographiccitation.journal","Brain"],["dc.bibliographiccitation.volume","134"],["dc.contributor.author","Bachmann, Cornelius G."],["dc.contributor.author","Rolke, Roman"],["dc.contributor.author","Scheidt, Uta"],["dc.contributor.author","Stadelmann, Christine"],["dc.contributor.author","Sommer, Martin"],["dc.contributor.author","Pavlakovic, Goran"],["dc.contributor.author","Happe, Svenja"],["dc.contributor.author","Treede, Rolf-Detlef"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T08:57:30Z"],["dc.date.available","2018-11-07T08:57:30Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1093/brain/awq292"],["dc.identifier.isi","000289163300005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23412"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","0006-8950"],["dc.title","Reply: Sensory profile in primary restless legs syndrome and restless legs syndrome associated with small fibre neuropathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]