Bauerschmitz, Gerd Johannes

[["dc.bibliographiccitation.firstpage","418"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Cancers"],["dc.bibliographiccitation.volume","14"],["dc.contributor.affiliation","Woelber, Linn; 1Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg—Eppendorf, 20246 Hamburg, Germany; k.prieske@uke.de (K.P.); j.hambrecht@uke.de (J.H.); a.jaeger@uke.de (A.J.)"],["dc.contributor.affiliation","Hampl, Monika; 3Department of Gynecology, University Medical Center Duesseldorf, 40225 Duesseldorf, Germany; hampl@med.uni-duesseldorf.de"],["dc.contributor.affiliation","Eulenburg, Christine zu; 4Department of Epidemiology, UMCG, Universität Groningen, 9713 Groningen, The Netherlands; christine.eulenburg@googlemail.com"],["dc.contributor.affiliation","Prieske, Katharina; 1Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg—Eppendorf, 20246 Hamburg, Germany; k.prieske@uke.de (K.P.); j.hambrecht@uke.de (J.H.); a.jaeger@uke.de (A.J.)"],["dc.contributor.affiliation","Hambrecht, Johanna; 1Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg—Eppendorf, 20246 Hamburg, Germany; k.prieske@uke.de (K.P.); j.hambrecht@uke.de (J.H.); a.jaeger@uke.de (A.J.)"],["dc.contributor.affiliation","Fuerst, Sophie; 6Department of Obstetrics and Gynecology, University Hospital, LMU—University of Munich, 80377 Munich, Germany; sophie.fuerst@med.uni-muenchen.de (S.F.); sven.mahner@med.uni-muenchen.de (S.M.)"],["dc.contributor.affiliation","Klapdor, Ruediger; 7Department of Obstetrics and Gynecology, Hannover Medical School, 30625 Hannover, Germany; klapdor.ruediger@mh-hannover.de"],["dc.contributor.affiliation","Heublein, Sabine; 8Department of Obstetrics and Gynecology, University Hospital Heidelberg, 69120 Heidelberg, Germany; sabine.heublein@med.uni-heidelberg.de"],["dc.contributor.affiliation","Gass, Paul; 9Department of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany; paul.gass@uk-erlangen.de"],["dc.contributor.affiliation","Rohner, Annika; 10Department of Gynecology, University Medical Center Tuebingen, 72076 Tuebingen, Germany; Annika.Rohner@med.uni-tuebingen.de"],["dc.contributor.affiliation","Canzler, Ulrich; 11Department of Gynecology and Obstetrics, University Hospital Dresden, Technische Universität Dresden, Dresden, Germany & National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany; ulrich.canzler@uniklinikum-dresden.de"],["dc.contributor.affiliation","Becker, Sven; 12Department of Gynecology and Obstetrics, University Medical Center Frankfurt, 60590 Frankfurt, Germany; sven.becker@kgu.de"],["dc.contributor.affiliation","Bommert, Mareike; 13Department of Gynecology and Gynecologic Oncology, Evang. Kliniken Essen-Mitte, 45136 Essen, Germany; m.bommert@kem-med.com"],["dc.contributor.affiliation","Bauerschlag, Dirk; 14Department of Gynecology, University Medical Center Kiel, 24105 Kiel, Germany; dirk.bauerschlag@uksh.de"],["dc.contributor.affiliation","Denecke, Agnieszka; 15Department of Gynecology, Medical Center Wolfsburg, 38440 Wolfsburg, Germany; agnieszka.denecke@klinikum.wolfsburg.de"],["dc.contributor.affiliation","Hanker, Lars; 16Department of Gynecology and Gynecologic Oncology, University Medical Center Luebeck, 23562 Luebeck, Germany; lars.hanker@uksh.de"],["dc.contributor.affiliation","Runnebaumn, Ingo; 17Department of Gynecology, Jena University Hospital, 07743 Jena, Germany; Ingo.Runnebaum@med.uni-jena.de"],["dc.contributor.affiliation","Forner, Dirk M.; 18Department of Gynecology, Evangelisches Krankenhaus Kalk, 51103 Cologne, Germany; dirk.forner@evkk.de"],["dc.contributor.affiliation","Schochter, Fabienne; 19Department of Obstetrics and Gynecology, University of Ulm Medical Center, 89081 Ulm, Germany; fabienne.schochter@uniklinik-ulm.de"],["dc.contributor.affiliation","Klar, Maximilian; 20Department of Gynecology, University Medical Center Freiburg, 79106 Freiburg, Germany; maximilian.klar@uniklinik-freiburg.de"],["dc.contributor.affiliation","Schwab, Roxana; 21Department of Gynecology, University Medical Center Mainz, 55131 Mainz, Germany; Roxana.Schwab@unimedizin-mainz.de"],["dc.contributor.affiliation","Koepke, Melitta; 22Department of Obstetrics and Gynaecology, University Hospital Augsburg, 86156 Augsburg, Germany; melitta.koepke@uk-augsburg.de (M.K.); christian.dannecker@med.uni-augsburg.de (C.D.)"],["dc.contributor.affiliation","Kalder, Matthias; 23Department of Gynecology and Obstetrics, University Hospital Marburg, 35043 Marburg, Germany; kalder@med.uni-marburg.de"],["dc.contributor.affiliation","Hantschmann, Peer; 24Department of Gynecology and Obstetrics, Medical Center Altoetting, 84503 Altoetting, Germany; p.hantschmann@innklinikum.de"],["dc.contributor.affiliation","Ratiu, Dominik; 25Department of Gynecology, University Medical Center Koeln, 50937 Koeln, Germany; dominik.ratiu@uk-koeln.de"],["dc.contributor.affiliation","Denschlag, Dominik; 26Department of Gynecology, Hochtaunuskliniken, 61352 Bad Homburg, Germany; dominik.denschlag@hochtaunus-kliniken.de"],["dc.contributor.affiliation","Schroeder, Willibald; 27Department of Gynecology, Medical Center Gynaecologicum Bremen, 28209 Bremen, Germany; prof.schroeder@gynaekologikum-bremen.de"],["dc.contributor.affiliation","Tuschy, Benjamin; 28Department of Gynecology, University Medical Center Mannheim, 68167 Mannheim, Germany; benjamin.tuschy@umm.de"],["dc.contributor.affiliation","Baumann, Klaus; 29Department of Gynecology, Medical Center Ludwigshafen, 67063 Ludwigshafen, Germany; baumann@klilu.de"],["dc.contributor.affiliation","Mustea, Alexander; 30Department of Gynecology and Gynecologic Oncology, University Medical Center Bonn, 53127 Bonn, Germany; alexander.mustea@ukbonn.de"],["dc.contributor.affiliation","Soergel, Philipp; 31Department of Gynecology, University Medical Center Minden, 32429 Minden, Germany; philipp.soergel@muehlenkreiskliniken.de"],["dc.contributor.affiliation","Bronger, Holger; 32Department of Gynecology and Obstetrics, Technical University of Munich, 81675 Munich, Germany; holger.bronger@tum.de"],["dc.contributor.affiliation","Bauerschmitz, Gerd; 33Department of Gynecology, University Medical Center Goettingen, 37075 Goettingen, Germany; gerd.bauerschmitz@med.uni-goettingen.de"],["dc.contributor.affiliation","Kosse, Jens; 34Department of Gynecology, Sana Klinikum Offenbach, 63069 Offenbach am Main, Germany; jens.kosse@sana.de"],["dc.contributor.affiliation","Koch, Martin C.; 35Department of Gynecology, Medical Center Ansbach, 91522 Ansbach, Germany; martin.koch@anregiomed.de"],["dc.contributor.affiliation","Ignatov, Atanas; 36Department of Obstetrics and Gynecology, University Hospital Magdeburg, 39120 Magdeburg, Germany; atanas.ignatov@med.ovgu.de"],["dc.contributor.affiliation","Sehouli, Jalid; 37Department of Gynecology with Center for Oncological SurgeryNOGGO e.V., Charite Universitatsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Virchow Campus Clinic, Charité Medical University, 13353 Berlin, Germany; jalid.sehouli@charite.de"],["dc.contributor.affiliation","Dannecker, Christian; 22Department of Obstetrics and Gynaecology, University Hospital Augsburg, 86156 Augsburg, Germany; melitta.koepke@uk-augsburg.de (M.K.); christian.dannecker@med.uni-augsburg.de (C.D.)"],["dc.contributor.affiliation","Mahner, Sven; 6Department of Obstetrics and Gynecology, University Hospital, LMU—University of Munich, 80377 Munich, Germany; sophie.fuerst@med.uni-muenchen.de (S.F.); sven.mahner@med.uni-muenchen.de (S.M.)"],["dc.contributor.affiliation","Jaeger, Anna; 1Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg—Eppendorf, 20246 Hamburg, Germany; k.prieske@uke.de (K.P.); j.hambrecht@uke.de (J.H.); a.jaeger@uke.de (A.J.)"],["dc.contributor.author","Woelber, Linn"],["dc.contributor.author","Hampl, Monika"],["dc.contributor.author","Eulenburg, Christine zu"],["dc.contributor.author","Prieske, Katharina"],["dc.contributor.author","Hambrecht, Johanna"],["dc.contributor.author","Fuerst, Sophie"],["dc.contributor.author","Klapdor, Ruediger"],["dc.contributor.author","Heublein, Sabine"],["dc.contributor.author","Gass, Paul"],["dc.contributor.author","Rohner, Annika"],["dc.contributor.author","Jaeger, Anna"],["dc.contributor.author","Bauerschmitz, Gerd"],["dc.contributor.editor","Preti, Mario"],["dc.contributor.editor","Querleu, Denis"],["dc.date.accessioned","2022-02-01T10:31:45Z"],["dc.date.available","2022-02-01T10:31:45Z"],["dc.date.issued","2022"],["dc.date.updated","2022-02-09T13:18:26Z"],["dc.description.abstract","The need for pelvic treatment in patients with node-positive vulvar cancer (VSCC) and the value of pelvic lymphadenectomy (LAE) as a staging procedure to plan adjuvant radiotherapy (RT) is controversial. In this retrospective, multicenter analysis, 306 patients with primary node-positive VSCC treated at 33 gynecologic oncology centers in Germany between 2017 and 2019 were analyzed. All patients received surgical staging of the groins; nodal status was as follows: 23.9% (73/306) pN1a, 23.5% (72/306) pN1b, 20.4% (62/306) pN2a/b, and 31.9% (97/306) pN2c/pN3. A total of 35.6% (109/306) received pelvic LAE; pelvic nodal involvement was observed in 18.5%. None of the patients with nodal status pN1a or pN1b and pelvic LAE showed pelvic nodal involvement. Taking only patients with nodal status ≥pN2a into account, the rate of pelvic involvement was 25%. In total, adjuvant RT was applied in 64.4% (197/306). Only half of the pelvic node-positive (N+) patients received adjuvant RT to the pelvis (50%, 10/20 patients); 41.9% (122/291 patients) experienced recurrent disease or died. In patients with histologically-confirmed pelvic metastases after LAE, distant recurrences were most frequently observed (7/20 recurrences). Conclusions: A relevant risk regarding pelvic nodal involvement was observed from nodal status pN2a and higher. Our data support the omission of pelvic treatment in patients with nodal status pN1a and pN1b."],["dc.description.abstract","The need for pelvic treatment in patients with node-positive vulvar cancer (VSCC) and the value of pelvic lymphadenectomy (LAE) as a staging procedure to plan adjuvant radiotherapy (RT) is controversial. In this retrospective, multicenter analysis, 306 patients with primary node-positive VSCC treated at 33 gynecologic oncology centers in Germany between 2017 and 2019 were analyzed. All patients received surgical staging of the groins; nodal status was as follows: 23.9% (73/306) pN1a, 23.5% (72/306) pN1b, 20.4% (62/306) pN2a/b, and 31.9% (97/306) pN2c/pN3. A total of 35.6% (109/306) received pelvic LAE; pelvic nodal involvement was observed in 18.5%. None of the patients with nodal status pN1a or pN1b and pelvic LAE showed pelvic nodal involvement. Taking only patients with nodal status ≥pN2a into account, the rate of pelvic involvement was 25%. In total, adjuvant RT was applied in 64.4% (197/306). Only half of the pelvic node-positive (N+) patients received adjuvant RT to the pelvis (50%, 10/20 patients); 41.9% (122/291 patients) experienced recurrent disease or died. In patients with histologically-confirmed pelvic metastases after LAE, distant recurrences were most frequently observed (7/20 recurrences). Conclusions: A relevant risk regarding pelvic nodal involvement was observed from nodal status pN2a and higher. Our data support the omission of pelvic treatment in patients with nodal status pN1a and pN1b."],["dc.identifier.doi","10.3390/cancers14020418"],["dc.identifier.eissn","2072-6694"],["dc.identifier.pii","cancers14020418"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98940"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.publisher","MDPI"],["dc.relation.eissn","2072-6694"],["dc.rights","Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."],["dc.title","Risk for Pelvic Metastasis and Role of Pelvic Lymphadenectomy in Node-Positive Vulvar Cancer-Results from the AGO-VOP.2 QS Vulva Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]