Schnabel, Viktor

[["dc.bibliographiccitation.journal","Journal of Cancer Research and Clinical Oncology"],["dc.contributor.author","Kretschmer, Lutz"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Kromer, Christian"],["dc.contributor.author","Bauer-Büntzel, Christoph"],["dc.contributor.author","Richter, Annika"],["dc.contributor.author","Bremmer, Felix"],["dc.contributor.author","Kück, Fabian"],["dc.contributor.author","Julius, Katharina"],["dc.contributor.author","Mitteldorf, Christina"],["dc.contributor.author","Schön, Michael P."],["dc.date.accessioned","2022-02-01T10:31:54Z"],["dc.date.available","2022-02-01T10:31:54Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract Purpose Melanocytic nevi in lymph nodes (NNs) are an important histological differential diagnosis of initial sentinel lymph node (SN) metastasis in melanoma. Our aim was to associate NN in SNs with clinicopathologic features and survival rates in 1, 250 patients with SN biopsy for melanoma. Methods To compare patients with present and absent NN, we used Fisher's exact test, Mann–Whitney U test, and multivariate logistic regression models in this retrospective observational study based on a prospectively maintained institutional database. Results NN prevalence in axillary, cervical, and groin SNs was 16.5%, 19.4%, and 9.8%, respectively. NN were observed in combination with all growth patterns of melanoma, but more frequently when the primary was histologically associated with a cutaneous nevus. We observed a decreasing NN prevalence with increasing SN metastasis diameter. Multiple logistic regression determined a significantly increased NN probability for SNs of the neck or axilla, for individuals with ≥ 50 cutaneous nevi, midline primary melanomas, and for individuals who reported non-cutaneous malignancies in their parents. Cancer in parents was also significantly more frequently reported by melanoma patients who had more than 50 cutaneous nevi. In SN-negative patients, NN indicated a tendency for slightly lower melanoma-specific survival. Conclusions We found a highly significant association between NN diagnosis and multiple cutaneous nevi and provided circumstantial evidence that cutaneous nevi in the drainage area of lymph nodes are particularly important. The trend toward lower melanoma-specific survival in SN-negative patients with NN suggests that careful differentiation of SN metastases is important."],["dc.description.abstract","Abstract Purpose Melanocytic nevi in lymph nodes (NNs) are an important histological differential diagnosis of initial sentinel lymph node (SN) metastasis in melanoma. Our aim was to associate NN in SNs with clinicopathologic features and survival rates in 1, 250 patients with SN biopsy for melanoma. Methods To compare patients with present and absent NN, we used Fisher's exact test, Mann–Whitney U test, and multivariate logistic regression models in this retrospective observational study based on a prospectively maintained institutional database. Results NN prevalence in axillary, cervical, and groin SNs was 16.5%, 19.4%, and 9.8%, respectively. NN were observed in combination with all growth patterns of melanoma, but more frequently when the primary was histologically associated with a cutaneous nevus. We observed a decreasing NN prevalence with increasing SN metastasis diameter. Multiple logistic regression determined a significantly increased NN probability for SNs of the neck or axilla, for individuals with ≥ 50 cutaneous nevi, midline primary melanomas, and for individuals who reported non-cutaneous malignancies in their parents. Cancer in parents was also significantly more frequently reported by melanoma patients who had more than 50 cutaneous nevi. In SN-negative patients, NN indicated a tendency for slightly lower melanoma-specific survival. Conclusions We found a highly significant association between NN diagnosis and multiple cutaneous nevi and provided circumstantial evidence that cutaneous nevi in the drainage area of lymph nodes are particularly important. The trend toward lower melanoma-specific survival in SN-negative patients with NN suggests that careful differentiation of SN metastases is important."],["dc.identifier.doi","10.1007/s00432-021-03894-y"],["dc.identifier.pii","3894"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98974"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.eissn","1432-1335"],["dc.relation.issn","0171-5216"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Melanocytic nevi in sentinel lymph nodes: association with cutaneous nevi and clinical relevance in patients with cutaneous melanomas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","850"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Der Hautarzt"],["dc.bibliographiccitation.lastpage","854"],["dc.bibliographiccitation.volume","71"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Thoms, Kai-Martin"],["dc.date.accessioned","2021-04-14T08:23:38Z"],["dc.date.available","2021-04-14T08:23:38Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00105-020-04689-x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80996"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1432-1173"],["dc.relation.issn","0017-8470"],["dc.title","Wunde und Kompression"],["dc.title.translated","Wounds and compression"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","jdv.18353"],["dc.bibliographiccitation.journal","Journal of the European Academy of Dermatology and Venereology"],["dc.contributor.author","Stanisz, H."],["dc.contributor.author","Beutner, C."],["dc.contributor.author","Kretschmer, L."],["dc.contributor.author","Schuppe, M. C."],["dc.contributor.author","Schnabel, V."],["dc.contributor.author","Schön, M. P."],["dc.contributor.author","Mitteldorf, C."],["dc.date.accessioned","2022-07-01T07:35:14Z"],["dc.date.available","2022-07-01T07:35:14Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1111/jdv.18353"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112117"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-581"],["dc.relation.eissn","1468-3083"],["dc.relation.issn","0926-9959"],["dc.rights.uri","http://onlinelibrary.wiley.com/termsAndConditions#vor"],["dc.title","Neuropathy as an early warning sign of desmoplastic neurotropic melanoma of the head"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Dermatological Science"],["dc.contributor.author","Hermasch, Matthias Andreas"],["dc.contributor.author","Janning, Helena"],["dc.contributor.author","Perera, Roshan Priyarangana"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Rostam, Nadia"],["dc.contributor.author","Ramos-Gomes, Fernanda"],["dc.contributor.author","Muschalek, Wiebke"],["dc.contributor.author","Bennemann, Anette"],["dc.contributor.author","Alves, Frauke"],["dc.contributor.author","Ralser, Damian Johannes"],["dc.contributor.author","Frank, Jorge"],["dc.date.accessioned","2022-02-01T10:32:10Z"],["dc.date.available","2022-02-01T10:32:10Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.jdermsci.2022.01.001"],["dc.identifier.pii","S0923181122000019"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/99022"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.issn","0923-1811"],["dc.title","Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Broekaert, Sigrid M. C."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Moessner, R."],["dc.date.accessioned","2018-11-07T10:25:21Z"],["dc.date.available","2018-11-07T10:25:21Z"],["dc.date.issued","2017"],["dc.format.extent","160"],["dc.identifier.isi","000400154800408"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42844"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Wiley"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Clearance of annular pustular psoriasis under treatment with Ustekinumab"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","296"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Journal of Allergy and Clinical Immunology. In Practice"],["dc.bibliographiccitation.lastpage","297.e1"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Schupp, Peter"],["dc.contributor.author","Gutgesell, Carsten"],["dc.contributor.author","Braun, Andrea"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Fuchs, Thomas"],["dc.contributor.author","Buhl, Timo"],["dc.date.accessioned","2020-12-10T14:24:46Z"],["dc.date.available","2020-12-10T14:24:46Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.jaip.2018.06.021"],["dc.identifier.issn","2213-2198"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72351"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Common food flavors are safe in patients with urticaria or atopic dermatitis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","960"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.lastpage","964"],["dc.bibliographiccitation.volume","139"],["dc.contributor.author","Ralser, Damian J."],["dc.contributor.author","Takeuchi, Hideyuki"],["dc.contributor.author","Fritz, Günter"],["dc.contributor.author","Basmanav, F. Buket"],["dc.contributor.author","Effern, Maike"],["dc.contributor.author","Sivalingam, Sugirthan"],["dc.contributor.author","El-Shabrawi-Caelen, Laila"],["dc.contributor.author","Degirmentepe, Ece N."],["dc.contributor.author","Kocatürk, Emek"],["dc.contributor.author","Singh, Manuraj"],["dc.contributor.author","Booken, Nina"],["dc.contributor.author","Spierings, Natalia M.K."],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Heineke, Andre"],["dc.contributor.author","Knuever, Jana"],["dc.contributor.author","Wolf, Sabrina"],["dc.contributor.author","Wehner, Maria"],["dc.contributor.author","Tronnier, Michael"],["dc.contributor.author","Leverkus, Martin"],["dc.contributor.author","Tantcheva-Poór, Iliana"],["dc.contributor.author","Wenzel, Jörg"],["dc.contributor.author","Oji, Vinzenz"],["dc.contributor.author","Has, Cristina"],["dc.contributor.author","Hölzel, Michael"],["dc.contributor.author","Frank, Jorge"],["dc.contributor.author","Haltiwanger, Robert S."],["dc.contributor.author","Betz, Regina C."],["dc.date.accessioned","2020-12-10T14:25:11Z"],["dc.date.available","2020-12-10T14:25:11Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.jid.2018.10.030"],["dc.identifier.issn","0022-202X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72471"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Altered Notch Signaling in Dowling-Degos Disease: Additional Mutations in POGLUT1 and Further Insights into Disease Pathogenesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","124"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Melanoma Research"],["dc.bibliographiccitation.lastpage","127"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Kromer, Christian"],["dc.contributor.author","Vlahova, Lyubomira D."],["dc.contributor.author","Julius, Katharina"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Reuter-Jessen, Kirsten"],["dc.contributor.author","Seif Amir Hosseini, Ali"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2022-04-01T10:00:30Z"],["dc.date.available","2022-04-01T10:00:30Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1097/CMR.0000000000000773"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105447"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.issn","0960-8931"],["dc.title","Response of metastatic melanoma with a rare BRAF V600K mutation to dabrafenib and trametinib"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","527"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","529"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Julius, Katharina"],["dc.contributor.author","Kromer, Christian"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Vlahova, Lyubomira"],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Sahlmann, Carsten‐Oliver"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2022-05-02T08:02:26Z"],["dc.date.available","2022-05-02T08:02:26Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1111/ddg.14737_g"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107319"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-561"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.rights.uri","http://creativecommons.org/licenses/by-nc/4.0/"],["dc.title","Ansprechen eines metastasierten akrolentiginösen Melanoms mit Exon‐11‐BRAF‐G469A‐Mutation auf BRAF/MEK‐Inhibition"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","ddg.14531"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.contributor.author","Kromer, Christian"],["dc.contributor.author","Vlahova, Lyubomira D."],["dc.contributor.author","Julius, Katharina"],["dc.contributor.author","Schnabel, Viktor"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Gottberg, Philipp V."],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2021-08-12T07:45:21Z"],["dc.date.available","2021-08-12T07:45:21Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1111/ddg.14531"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88440"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Subgaleal infiltration improves MRI‐supported surgical planning for scalp tumors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]