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Noll, Christine
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Noll, Christine
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Noll, Christine
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Noll, C.
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2010Journal Article [["dc.bibliographiccitation.firstpage","33"],["dc.bibliographiccitation.issue","1-3"],["dc.bibliographiccitation.journal","European Journal of Pharmacology"],["dc.bibliographiccitation.lastpage","38"],["dc.bibliographiccitation.volume","633"],["dc.contributor.author","Boeer, Ulrike"],["dc.contributor.author","Noll, Christine"],["dc.contributor.author","Cierny, Irmgard"],["dc.contributor.author","Krause, Doris"],["dc.contributor.author","Hiemke, Christoph"],["dc.contributor.author","Knepel, Willhart"],["dc.date.accessioned","2018-11-07T08:43:16Z"],["dc.date.available","2018-11-07T08:43:16Z"],["dc.date.issued","2010"],["dc.description.abstract","The transcription factor CREB regulates adaptive responses like memory consolidation, addiction, and synaptic refinement. Recently, chronic psychosocial stress as animal model of depression has been shown to stimulate CREB transcriptional activity in the brain; this stimulation was prevented by treatment with the antidepressant imipramine, which inhibits both noradrenaline and serotonin reuptake. However, it was unknown whether the selective inhibition of serotonin reuptake is sufficient for inhibition of stress-induced CREB activation, as it is for the clinical antidepressant effect. Therefore, the effect of two selective serotonin reuptake inhibitors (SSRIs), citalopram and fluoxetine, was examined in this study. Transgenic CRE-luciferase reporter gene mice were used to monitor gene transcription directed by the CREB DNA binding site (CRE) in vivo. Chronic psychosocial stress for 25 days stimulated CRE/CREB-directed luciferase expression in the hippocampus and other brain regions. When applied alone to non-stressed mice, citalopram caused a transient increase after 24 h that was lost after 21 days of treatment, whereas fluoxetine had no effect after 24 h and produced an inhibition in the pons and hypothalamus after 21 days of treatment. However, both citalopram and fluoxetine treatment completely abolished the increase in CRE/CREB-directed transcription induced by chronic psychosocial stress. As indicated by Western blots, the changes in CRE/CREB-directed transcription were accompanied by corresponding changes in the phosphorylation of CREB at serine-119. These results further emphasize the role of CREB in stress-induced gene expression and suggest furthermore that inhibition of stress-induced CREB activity may be a common mechanism of action of SSRIs underlying their antidepressive effect. (C) 2010 Elsevier B.V. All rights reserved."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [SFB 402 (A3)]"],["dc.identifier.doi","10.1016/j.ejphar.2010.01.016"],["dc.identifier.isi","000276701500005"],["dc.identifier.pmid","20122921"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19919"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0014-2999"],["dc.title","A common mechanism of action of the selective serotonin reuptake inhibitors citalopram and fluoxetine: Reversal of chronic psychosocial stress-induced increase in CRE/CREB-directed gene transcription in transgenic reporter gene mice"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2022Journal Article [["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Physical Review B"],["dc.bibliographiccitation.volume","106"],["dc.contributor.author","Dang, T. T."],["dc.contributor.author","Schell, J."],["dc.contributor.author","Boa, A. G."],["dc.contributor.author","Lewin, D."],["dc.contributor.author","Marschick, G."],["dc.contributor.author","Dubey, A."],["dc.contributor.author","Escobar-Castillo, M."],["dc.contributor.author","Noll, C."],["dc.contributor.author","Beck, R."],["dc.contributor.author","Zyabkin, Dmitry V."],["dc.contributor.author","Lupascu, D. C."],["dc.date.accessioned","2022-09-01T09:50:36Z"],["dc.date.available","2022-09-01T09:50:36Z"],["dc.date.issued","2022"],["dc.description.sponsorship"," Bundesministerium fĂĽr Bildung und Forschung http://dx.doi.org/10.13039/501100002347"],["dc.description.sponsorship"," Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659"],["dc.identifier.doi","10.1103/PhysRevB.106.054416"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113754"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","2469-9969"],["dc.relation.issn","2469-9950"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Temperature dependence of the local electromagnetic field at the Fe site in multiferroic bismuth ferrite"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2017Journal Article [["dc.bibliographiccitation.firstpage","143"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Technology and Health Care"],["dc.bibliographiccitation.lastpage","151"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Noll, Christine"],["dc.contributor.author","Steitz, Vanessa"],["dc.contributor.author","Daentzer, Dorothea"],["dc.date.accessioned","2020-12-10T18:44:15Z"],["dc.date.available","2020-12-10T18:44:15Z"],["dc.date.issued","2017"],["dc.description.abstract","PURPOSE: Proprioceptive insoles are known to influence the functions of posture and gait by modulations of the sensory structures at the sole of the foot. Literature has shown that they could improve the position of the upper-body in patients with postural complaints of the musculoskeletal system. The aim of this study was to evaluate the influence of proprioceptive insoles on the spinal curvature in patients with slight idiopathic scoliosis. PATIENTS AND METHODS: Eighteen patients were included in this prospective, single-centre, randomized study. All patients needed to have a relevant growth potential and suffered from a slight idiopathic scoliosis. Two groups were used, where group 1 performed physiotherapy twice a week, whereas group 2 was additionally supplied with proprioceptive insoles. Patients underwent three-dimensional rasterstereography for back-shape analysis. Furthermore, a conventional x-ray imaging of the spine was performed at the beginning and 1 year later to document the curvatures. RESULTS: There was no statistical difference in the Cobb angles, and in almost all parameters of the rasterstereography, there was no statistically significant change between and within both groups. CONCLUSION: According to the results of this study, there was no evidence of any statistical significant effect of proprioceptive insoles on spinal curvature in patients with slight idiopathic scoliosis."],["dc.identifier.doi","10.3233/THC-161271"],["dc.identifier.eissn","1878-7401"],["dc.identifier.isi","000395829700012"],["dc.identifier.issn","0928-7329"],["dc.identifier.pmid","27886017"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78379"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Ios Press"],["dc.relation.issn","1878-7401"],["dc.relation.issn","0928-7329"],["dc.title","Influence of proprioceptive insoles on spinal curvature in patients with slight idiopathic scoliosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS