Frahm, Jens

[["dc.bibliographiccitation.artnumber","e0268523"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Gräfe, Daniel"],["dc.contributor.author","Päts, Anne"],["dc.contributor.author","Merkenschlager, Andreas"],["dc.contributor.author","Roth, Christian"],["dc.contributor.author","Hirsch, Franz Wolfgang"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Voit, Dirk"],["dc.contributor.editor","Lundberg, Peter"],["dc.date.accessioned","2022-06-01T09:39:45Z"],["dc.date.available","2022-06-01T09:39:45Z"],["dc.date.issued","2022"],["dc.description.abstract","Purpose Diffusion-weighted imaging (DWI) is an essential element of almost every brain MRI examination. The most widely applied DWI technique, a single-shot echo-planar imaging DWI (EPI-DWI) sequence, suffers from a high sensitivity to magnetic field inhomogeneities. As an alternative, a single-shot stimulated echo acquisition mode diffusion-weighted MRI (STEAM-DWI) has recently been re-introduced after it became significantly faster. The aim of the study was to investigate the applicability of STEAM-DWI as a substitute to EPI-DWI in a daily routine of pediatric radiology. Methods Retrospectively, brain MRI examinations of 208 children with both EPI-DWI and STEAM-DWI were assessed. Visual resolution and diagnostic confidence were evaluated, the extent of susceptibility artifacts was quantified, and contrast-to-noise ratio was calculated in case of diffusion restriction. Furthermore, the correlation of apparent diffusion coefficient values between STEAM-DWI and EPI-DWI was tested. Results STEAM-DWI was inferior to EPI-DWI in visual resolution but with higher diagnostic confidence and lower artifact size. The apparent diffusion coefficient values of both sequences demonstrated excellent correlation. The contrast-to-noise ratio of STEAM-DWI was only half of that of EPI-DWI (58% resp. 112%). Conclusion STEAM-DWI is a robust alternative to EPI-DWI when increased susceptibility artifacts are to be expected. Drawbacks are a lower contrast-to-noise ratio and poorer visual resolution."],["dc.identifier.doi","10.1371/journal.pone.0268523"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108553"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","1932-6203"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","STEAM-DWI as a robust alternative to EPI-DWI: Evaluation in pediatric brain MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]