Beham, Alexander Wilhelm

[["dc.bibliographiccitation.journal","The Journal of Immunology"],["dc.bibliographiccitation.volume","182"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Kzhyshkowska, Julia"],["dc.contributor.author","Gratchev, Alexei"],["dc.contributor.author","Laird, Rebecca"],["dc.contributor.author","Wessels, Johannes Theodor"],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Ganser, Arnold"],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T08:31:11Z"],["dc.date.available","2018-11-07T08:31:11Z"],["dc.date.issued","2009"],["dc.identifier.isi","000209763602309"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17065"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Immunologists"],["dc.publisher.place","Bethesda"],["dc.relation.issn","1550-6606"],["dc.relation.issn","0022-1767"],["dc.title","Macrophages express a TCR alpha beta-based variable immunoreceptor"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","39"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Immunobiology"],["dc.bibliographiccitation.lastpage","44"],["dc.bibliographiccitation.volume","222"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Hahn, Martin"],["dc.contributor.author","Riabov, Vladimir"],["dc.contributor.author","Yin, Shuiping"],["dc.contributor.author","Kzhyshkowska, Julia"],["dc.contributor.author","Busch, Svenja"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T10:29:34Z"],["dc.date.available","2018-11-07T10:29:34Z"],["dc.date.issued","2017"],["dc.description.abstract","Recent evidence indicates the presence of macrophage subpopulations that express the TCR alpha beta in two major inflammatory diseases, tuberculosis and atherosclerosis. Inflammation is also a well-established attribute of cancer progression and macrophages are one of the major immune cells that infiltrate tumors. Here, we demonstrate that the macrophage-TCR alpha beta is expressed in the tumor microenvironment of human and murine malignancies. We identify TCR alpha beta(+) macrophages in each case of four randomly selected distinct human tumor entities. In human tumor tissues, the TCR alpha beta expressed by macrophages in the tumor microenvironment is a combinatorial and individual-specific immune receptor. Furthermore, we routinely find TCR alpha beta(+) macrophage subpopulations in experimental tumors (TS/A, mammary adenocarcinoma) which we induced both in normal mice and mice deficient in the macrophage receptor stabilin-1. Expression of the combinatorial murine tumor macrophage TCRotS is individual-specific and independent of stabilin-1. These results demonstrate that TCR alpha beta expression is a characteristic feature of macrophages in the tumor microenvironment and identify an as yet unrecognized flexible element in the macrophage-based host response to tumors. (C) 2015 Elsevier GmbH. All rights reserved."],["dc.identifier.doi","10.1016/j.imbio.2015.09.022"],["dc.identifier.isi","000390613800005"],["dc.identifier.pmid","26494401"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43664"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","0171-2985"],["dc.title","A combinatorial alpha beta T cell receptor expressed by macrophages in the tumor microenvironment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Neurology"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Dreyfus, David H."],["dc.contributor.author","Piehler, Armin P."],["dc.contributor.author","Reuter, Björn"],["dc.contributor.author","Schwarzbach, Christopher"],["dc.contributor.author","Willmann, Olaf"],["dc.contributor.author","Yepes, Diego"],["dc.contributor.author","Costina, Victor"],["dc.contributor.author","Findeisen, Peter"],["dc.contributor.author","Mahrt, Jens"],["dc.contributor.author","Wang, Chunlin"],["dc.contributor.author","Han, Jian"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2020-12-10T18:44:32Z"],["dc.date.available","2020-12-10T18:44:32Z"],["dc.date.issued","2019"],["dc.description.abstract","Bacterial meningitis is a life-threatening disease that evokes an intense neutrophil-dominated host response to microbes invading the subarachnoid space. Recent evidence indicates the existence of combinatorial V(D)J immune receptors in neutrophils that are based on the T cell receptor (TCR). Here, we investigated expression of the novel neutrophil TCRαβ-based V(D)J receptors in cerebrospinal fluid (CSF) from human patients with acute-phase bacterial meningitis using immunocytochemical, genetic immunoprofiling, cell biological, and mass spectrometric techniques. We find that the human neutrophil combinatorial V(D)J receptors are rapidly induced in CSF neutrophils during the first hours of bacterial meningitis. Immune receptor repertoire diversity is consistently increased in CSF neutrophils relative to circulating neutrophils and phagocytosis of baits directed to the variable immunoreceptor is enhanced in CSF neutrophils during acute-phase meningitis. Our results reveal that a flexible immune response involving neutrophil V(D)J receptors which enhance phagocytosis is immediately initiated at the site of acute bacterial infection."],["dc.identifier.doi","10.3389/fneur.2019.00307"],["dc.identifier.eissn","1664-2295"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78494"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1664-2295"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Immediate Neutrophil-Variable-T Cell Receptor Host Response in Bacterial Meningitis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","9823"],["dc.bibliographiccitation.journal","The Lancet"],["dc.bibliographiccitation.volume","379"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Schneider, Sven"],["dc.contributor.author","Kruth, Jens"],["dc.contributor.author","Schulze, Torsten J."],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T09:11:14Z"],["dc.date.available","2018-11-07T09:11:14Z"],["dc.date.issued","2012"],["dc.format.extent","1364"],["dc.identifier.isi","000302531100035"],["dc.identifier.pmid","22483032"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26671"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0140-6736"],["dc.title","An autoimmune double attack"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","960"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Immunobiology"],["dc.bibliographiccitation.lastpage","968"],["dc.bibliographiccitation.volume","218"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Hahn, Martin"],["dc.contributor.author","Dollt, Claudia"],["dc.contributor.author","Pechlivanidou, Ioanna"],["dc.contributor.author","Ovsiy, Ilja"],["dc.contributor.author","Kzhyshkowska, Julia"],["dc.contributor.author","Gratchev, Alexei"],["dc.contributor.author","Fleig, Julian"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T09:23:25Z"],["dc.date.available","2018-11-07T09:23:25Z"],["dc.date.issued","2013"],["dc.description.abstract","Recent evidence indicates that monocytes and macrophages express T cell receptor (TCR)alpha beta-like combinatorial immune receptors. Here, we demonstrate the presence of a second recombinatorial immunoreceptor, which is structurally based on the TCR gamma- and delta-chains, in human and murine monocytes and differentially activated macrophages (referred to here as TCRLm gamma delta). In vitro, infection of macrophages with mycobacteria and gram positive or gram negative bacteria induced expression of donor-specific and differential TCRLm V delta repertoires indicating that the novel immunoreceptor represents a dynamic flexible host defense system that responds to bacterial challenge. In vivo, we find that TCRLm gamma delta bearing macrophages, which express highly restricted repertoires of the antigen-binding V delta chain, accumulate in the cerebrospinal fluid in acute bacterial meningitis and in advanced lesions of atherosclerosis. These results identify an as yet unrecognized monocyte/macrophage subpopulation that bears combinatorial TCRLm gamma delta immune receptors, and is associated with both acute and chronic inflammatory diseases. Moreover, they indicate that the monocytic lineage uses the same bipartite system of TCR alpha beta/TCR gamma delta-based combinatorial immune receptors that is present in T cells. Our findings suggest specific roles of monocytes/macrophages in various inflammatory conditions and lend further evidence that flexible immune recognition in higher vertebrates operates on a broader cellular basis than previously thought. (c) 2013 Published by Elsevier GmbH."],["dc.description.sponsorship","Stiftung Pathobiochemie (DGKL); DFG [GRK880/3]; BMBF [RUS 10/B05]"],["dc.identifier.doi","10.1016/j.imbio.2012.11.005"],["dc.identifier.isi","000320485300004"],["dc.identifier.pmid","23312956"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29573"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","0171-2985"],["dc.title","A second combinatorial immune receptor in monocytes/macrophages is based on the TCR gamma delta"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","309"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Biochemical and Biophysical Research Communications"],["dc.bibliographiccitation.lastpage","315"],["dc.bibliographiccitation.volume","419"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Pueellmann, Kerstin"],["dc.contributor.author","Scharfenstein, Olivia"],["dc.contributor.author","Eichner, Romy"],["dc.contributor.author","Stobe, Elfi"],["dc.contributor.author","Becker, Anna"],["dc.contributor.author","Pechlivanidou, Ioanna"],["dc.contributor.author","Kzhyshkowska, Julia"],["dc.contributor.author","Gratchev, Alexei"],["dc.contributor.author","Ganser, Arnold"],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T09:12:22Z"],["dc.date.available","2018-11-07T09:12:22Z"],["dc.date.issued","2012"],["dc.description.abstract","Recent evidence has revealed the existence of T cell receptor (TCR) alpha beta-based recombinatorial immune receptors in phagocytes. Here, we performed a systematic survey of the variable beta-chain repertoires of the neutrophil TCR-like alpha beta immunoreceptor (referred to as TCRLn alpha beta) in defined cohorts of young and old individuals. Peripheral blood CD15(+) neutrophils from young adults (age 30 +/- 7 years, n = 12) expressed an average number of 13 +/- 6 distinct TCRLn V beta-chains from the total pool of 25 human V beta-chains. Neutrophils from aged subjects (age 76 +/- 6 years, n = 12) also consitutively express the TCRLn, however, only a small number of V beta-chains is used (4 +/- 2). Consistent with this, the average number of expressed CDR3 V beta length variants was fourfold higher in young individuals than in aged subjects (33 +/- 24 vs. 8 +/- 3). Young adults showed broad usage of all TCRLn V beta-chains. In contrast, >70 years individuals displayed a striking repertoire polarization towards the TCRLn V beta 1 and V beta 5b chains and a high degree of V beta 5b clonotype sharing. Our study reveals broad TCRLn repertoire diversity in young adults and demonstrates that the neutrophil variable immune receptor is expressed throughout the entire human life span. The marked decline in TCRLn repertoire diversity in old age identifies a novel mechanism of immunosenescence in neutrophils. (C) 2012 Elsevier Inc. All rights reserved."],["dc.description.sponsorship","Stiftung Pathobiochemie (DGKL) (WEK); Lesser-Loewe Foundation Mannheim"],["dc.identifier.doi","10.1016/j.bbrc.2012.02.017"],["dc.identifier.isi","000301911000031"],["dc.identifier.pmid","22342716"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26932"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","0006-291X"],["dc.title","The neutrophil recombinatorial TCR-like immune receptor is expressed across the entire human life span but repertoire diversity declines in old age"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e0204108"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","PLoS One"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Hahn, Martin"],["dc.contributor.author","Ries, Lukas"],["dc.contributor.author","Giesler, Sophie"],["dc.contributor.author","Busch, Svenja"],["dc.contributor.author","Wang, Chunlin"],["dc.contributor.author","Han, Jian"],["dc.contributor.author","Schulze, Torsten J."],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.editor","Haziot, Alain"],["dc.date.accessioned","2020-12-10T18:42:09Z"],["dc.date.available","2020-12-10T18:42:09Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1371/journal.pone.0204108"],["dc.identifier.eissn","1932-6203"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15701"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77824"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Expression of combinatorial immunoglobulins in macrophages in the tumor microenvironment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Clinical Chemistry and Laboratory Medicine (CCLM)"],["dc.bibliographiccitation.volume","49"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Scharfenstein, Olivia"],["dc.contributor.author","Stobe, Elfi"],["dc.contributor.author","Eichner, Romy"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T08:56:24Z"],["dc.date.available","2018-11-07T08:56:24Z"],["dc.date.issued","2011"],["dc.format.extent","S113"],["dc.identifier.isi","000289974200123"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23144"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Walter De Gruyter & Co"],["dc.publisher.place","Berlin"],["dc.relation.issn","1434-6621"],["dc.title","CHARACTERIZATION OF THE NEUTROPHIL-TCR IMMUNE RECEPTOR IN PATIENTS WITH SEPSIS OR SIRS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e1002375"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","PLoS Pathogens"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Laird, Rebecca"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Streich, Roswita"],["dc.contributor.author","Breysach, Caroline"],["dc.contributor.author","Raddatz, Dirk"],["dc.contributor.author","Oniga, Septimia"],["dc.contributor.author","Peccerella, Teresa"],["dc.contributor.author","Findeisen, Peter"],["dc.contributor.author","Kzhyshkowska, Julia"],["dc.contributor.author","Gratchev, Alexei"],["dc.contributor.author","Schweyer, Stefan"],["dc.contributor.author","Saunders, Bernadette"],["dc.contributor.author","Wessels, Johannes Theodor"],["dc.contributor.author","Möbius, Wiebke"],["dc.contributor.author","Keane, Joseph"],["dc.contributor.author","Becker, Heinz"],["dc.contributor.author","Ganser, Arnold"],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T08:50:08Z"],["dc.date.available","2018-11-07T08:50:08Z"],["dc.date.issued","2011"],["dc.description.abstract","Macrophages play a central role in host defense against mycobacterial infection and anti-TNF therapy is associated with granuloma disorganization and reactivation of tuberculosis in humans. Here, we provide evidence for the presence of a T cell receptor (TCR) alpha beta based recombinatorial immune receptor in subpopulations of human and mouse monocytes and macrophages. In vitro, we find that the macrophage-TCR alpha beta induces the release of CCL2 and modulates phagocytosis. TNF blockade suppresses macrophage-TCR alpha beta expression. Infection of macrophages from healthy individuals with mycobacteria triggers formation of clusters that express restricted TCR V beta repertoires. In vivo, TCR alpha beta bearing macrophages abundantly accumulate at the inner host-pathogen contact zone of caseous granulomas from patients with lung tuberculosis. In chimeric mouse models, deletion of the variable macrophage-TCR alpha beta or TNF is associated with structurally compromised granulomas of pulmonary tuberculosis even in the presence of intact T cells. These results uncover a TNF-regulated recombinatorial immune receptor in monocytes/macrophages and demonstrate its implication in granuloma formation in tuberculosis."],["dc.identifier.doi","10.1371/journal.ppat.1002375"],["dc.identifier.isi","000297337300037"],["dc.identifier.pmid","22114556"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7793"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21628"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1553-7374"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","A TNF-Regulated Recombinatorial Macrophage Immune Receptor Implicated in Granuloma Formation in Tuberculosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","59"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Biochemical and Biophysical Research Communications"],["dc.bibliographiccitation.lastpage","65"],["dc.bibliographiccitation.volume","456"],["dc.contributor.author","Fuchs, Tina"],["dc.contributor.author","Puellmann, Kerstin"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Fleig, Julian"],["dc.contributor.author","Oniga, Septimia"],["dc.contributor.author","Laird, Rebecca"],["dc.contributor.author","Heida, Nana Maria"],["dc.contributor.author","Schaefer, Katrin"],["dc.contributor.author","Neumaier, Michael"],["dc.contributor.author","Beham, Alexander W."],["dc.contributor.author","Kaminski, Wolfgang E."],["dc.date.accessioned","2018-11-07T10:02:23Z"],["dc.date.available","2018-11-07T10:02:23Z"],["dc.date.issued","2015"],["dc.description.abstract","Recent evidence indicates constitutive expression of a recombinatorial TCR alpha beta immune receptor in mammalian monocytes and macrophages. Here, we demonstrate in vitro that macrophage-TCR beta repertoires are modulated by atherogenic low density cholesterol (LDL) and high-density cholesterol (HDL). In vivo, analysis of freshly obtained artery specimens from patients with severe carotid atherosclerosis reveals massive abundance of TCR alpha beta(+) macrophages within the atherosclerotic lesions. Experimental atherosclerosis in mouse carotids induces accumulation of TCR bearing macrophages in the vascular wall and TCR deficient rag(-/-) mice have an altered macrophage-dependent inflammatory response. We find that the majority of TCR alpha beta bearing macrophages are localized in the hot spot regions of the atherosclerotic lesions. Advanced carotid artery lesions express highly restricted TCR alpha beta repertoires that are characterized by a striking usage of the V beta 22 and V beta 16 chains. This together with a significant degree of interindividual lesion repertoire sharing suggests the existence of atherosclerosis-associated TCR alpha beta signatures. Our results implicate the macrophage-TCR alpha beta combinatorial immunoreceptor in atherosclerosis and thus identify an as yet unknown adaptive component in the innate response-to-injury process that underlies this macrophage-driven disease. (C) 2014 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.bbrc.2014.11.034"],["dc.identifier.isi","000348483600010"],["dc.identifier.pmid","25446098"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38215"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1090-2104"],["dc.relation.issn","0006-291X"],["dc.title","The macrophage-TCR alpha beta is a cholesterol-responsive combinatorial immune receptor and implicated in atherosclerosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]