Reuß, Bernhard M.

[["dc.bibliographiccitation.firstpage","481"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Molecular Neuroscience"],["dc.bibliographiccitation.lastpage","505"],["dc.bibliographiccitation.volume","71"],["dc.contributor.author","Kleine, Aaron David"],["dc.contributor.author","Reuss, Bernhard"],["dc.date.accessioned","2021-04-14T08:23:33Z"],["dc.date.available","2021-04-14T08:23:33Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s12031-020-01670-0"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80963"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1559-1166"],["dc.relation.issn","0895-8696"],["dc.title","Interactions of Antibodies to the Gram-Negative Gastric Bacterium Helicobacter pylori with the Synaptic Calcium Sensor Synaptotagmin 5, Correlate to Impaired Vesicle Recycling in SiMa Human Neuroblastoma Cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Journal of Cell Biology"],["dc.bibliographiccitation.volume","84"],["dc.contributor.author","Hosseini, M."],["dc.contributor.author","Köster-Patzlaff, C."],["dc.contributor.author","Chowdhury, K."],["dc.contributor.author","Grebenshchikova, S."],["dc.contributor.author","Reuß, Bernhard"],["dc.date.accessioned","2018-11-07T11:19:12Z"],["dc.date.available","2018-11-07T11:19:12Z"],["dc.date.issued","2005"],["dc.format.extent","77"],["dc.identifier.isi","000228527700161"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55215"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.conference","Annual Meeting of the Deutsche-Gesellschaft-fur-Zellbiologie"],["dc.relation.eventlocation","Heidelberg, GERMANY"],["dc.relation.issn","0171-9335"],["dc.title","Differential genes expression in rats-hippocampus and -cerebellum after Borna disease virus infection"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","353"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Molecular Neuroscience"],["dc.bibliographiccitation.lastpage","365"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Reuss, Bernhard"],["dc.date.accessioned","2018-11-07T09:43:24Z"],["dc.date.available","2018-11-07T09:43:24Z"],["dc.date.issued","2014"],["dc.description.abstract","In children born from mothers with prenatal infections with the Gram-negative bacterium Neisseria gonorrhoeae, schizophrenia risk is increased in later life. Since cortical neuropil formation is frequently impaired during this disease, actions of a rabbit polyclonal antiserum directed to N. gonorrhoeae on neurite outgrowth in nerve growth factor-stimulated PC12 cells were investigated here. It turned out that 10 mu g/ml of the antiserum leads indeed to a significant reduction in neurite outgrowth, whereas an antiserum directed to Neisseria meningitidis had no such effect. Furthermore, reduction in neurite outgrowth could be reversed by the neuroleptic drugs haloperidol, clozapine, risperidone, and olanzapine. On the molecular level, the observed effects seem to include the known neuritogenic transcription factors FoxO3a and Stat3, since reduced neurite outgrowth caused by the antiserum was accompanied by a reduced phosphorylation of both factors. In contrast, restitution of neurite outgrowth by neuroleptic drugs revealed no correlation to the phosphorylation state of these factors. The present report gives a first hint that bacterial infections could indeed lead to impaired neuropil formation in vitro; however, the in vivo relevance of this finding for schizophrenia pathogenesis remains to be clarified in the future."],["dc.identifier.doi","10.1007/s12031-013-0156-8"],["dc.identifier.isi","000331699700005"],["dc.identifier.pmid","24203572"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34179"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Humana Press Inc"],["dc.relation.issn","1559-1166"],["dc.relation.issn","0895-8696"],["dc.title","Antibodies Directed to Neisseria gonorrhoeae Impair Nerve Growth Factor-Dependent Neurite Outgrowth in Rat PC12 Cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","489"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Molecular and Cellular Neuroscience"],["dc.bibliographiccitation.lastpage","494"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Ip, Chi Wang"],["dc.contributor.author","Kohl, Bianca"],["dc.contributor.author","Kleinschnitz, Christoph"],["dc.contributor.author","Reuss, Bernhard"],["dc.contributor.author","Nave, Klaus Armin"],["dc.contributor.author","Kroner, Antje"],["dc.contributor.author","Martini, Rudolf"],["dc.date.accessioned","2018-11-07T11:12:39Z"],["dc.date.available","2018-11-07T11:12:39Z"],["dc.date.issued","2008"],["dc.description.abstract","We have recently reported that overexpression of proteolipid protein in oligodendrocytes leads to a pathologically relevant increase of both CD8+ T-lymphocytes and CD11b+ cells in the CNS. We now focussed on the origin of the CD11b+ cells in the optic nerve, a well established structure for the analysis of the mutant, using bone marrow chimeric mice. Although there is an age-related increase in CD11b+ cells in the myelinated part of the optic nerve of the mutants, the percentage of infiltrating cells was not increased, but enhanced proliferation was detectable. In the non-myelinated optic nerve head, the Fate of infiltrating CD11b+ cells and albumin extravasation was high in both genotypes. However, albumin extravasation was also high in the rostral myelinated part, where CD11b+ cell influx was low. Our study demonstrates an intrinsic origin of CD11b+ cells in the presence of an unchanged blood-brain-barrier in a CNS myelin mutant. (C) 2008 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.mcn.2008.04.009"],["dc.identifier.isi","000258347300004"],["dc.identifier.pmid","18555697"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53713"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Academic Press Inc Elsevier Science"],["dc.relation.issn","1044-7431"],["dc.title","Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: Low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","383"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Notfall + Rettungsmedizin"],["dc.bibliographiccitation.lastpage","394"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Knapp, J."],["dc.contributor.author","Zylla, M."],["dc.contributor.author","Schaper, A."],["dc.contributor.author","Michalski, D."],["dc.contributor.author","Hartwig, S."],["dc.contributor.author","Bernhard, M."],["dc.date.accessioned","2020-12-10T14:11:09Z"],["dc.date.available","2020-12-10T14:11:09Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s10049-017-0386-3"],["dc.identifier.eissn","1436-0578"],["dc.identifier.issn","1434-6222"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70979"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Energydrinks in der Notfallmedizin – verleihen nicht nur Flügel"],["dc.title.alternative","Energy drinks in emergency medicine — give more than wings"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Neurochemistry"],["dc.bibliographiccitation.volume","94"],["dc.contributor.author","Reuss, Bernhard"],["dc.contributor.author","Dono, R."],["dc.contributor.author","Unsicker, Klaus"],["dc.date.accessioned","2018-11-07T11:01:41Z"],["dc.date.available","2018-11-07T11:01:41Z"],["dc.date.issued","2005"],["dc.format.extent","218"],["dc.identifier.isi","000231673401204"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51204"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.publisher.place","Malden"],["dc.relation.conference","20th Biennial Meeting of the International-Society-for-Neurochemistry/European-Society-for-Neurochemi stry"],["dc.relation.eventlocation","Innsbruck, AUSTRIA"],["dc.relation.issn","0022-3042"],["dc.title","Modulation of astroglial differentiation and functioning by fibroblast growth factors and its implications for blood brain barrier"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1110"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Immunologic Research"],["dc.bibliographiccitation.lastpage","1123"],["dc.bibliographiccitation.volume","65"],["dc.contributor.author","Almamy, Abdullah"],["dc.contributor.author","Schwerk, Christian"],["dc.contributor.author","Schroten, Horst"],["dc.contributor.author","Ishikawa, Hiroshi"],["dc.contributor.author","Asif, Abdul Rahman"],["dc.contributor.author","Reuss, Bernhard"],["dc.date.accessioned","2020-12-10T14:14:22Z"],["dc.date.available","2020-12-10T14:14:22Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s12026-017-8952-9"],["dc.identifier.eissn","1559-0755"],["dc.identifier.issn","0257-277X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71336"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","623"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Notfall + Rettungsmedizin"],["dc.bibliographiccitation.lastpage","627"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Michael, M."],["dc.contributor.author","Schulte, K."],["dc.contributor.author","Erkens, R."],["dc.contributor.author","Schaper, A."],["dc.contributor.author","Bernhard, M."],["dc.date.accessioned","2021-04-14T08:24:43Z"],["dc.date.available","2021-04-14T08:24:43Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s10049-020-00746-z"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81397"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1436-0578"],["dc.relation.issn","1434-6222"],["dc.title","Selbstintoxikation mit Lachgaskartusche"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","316"],["dc.bibliographiccitation.journal","Brain Research"],["dc.bibliographiccitation.lastpage","332"],["dc.bibliographiccitation.volume","1184"],["dc.contributor.author","Koester-Patzlaff, Christiane"],["dc.contributor.author","Hosseini, Seyed Mehdi"],["dc.contributor.author","Reuss, Bernhard"],["dc.date.accessioned","2018-11-07T10:45:04Z"],["dc.date.available","2018-11-07T10:45:04Z"],["dc.date.issued","2007"],["dc.description.abstract","Neonatal Borna Disease Virus (BDV) infection of the Lewis rat brain leads to dentate gyrus (DG) degeneration, underlying mechanisms are not fully understood. Since astroglial gap junction (GJ) coupling is known to influence neurodegenerative processes, the question arose whether persistent BDV infection influences astroglial connexins (Cx) Cx43 and Cx30 in the hippocampal formation (HiF) of Lewis rats. RT-PCR and Western blot analysis of forebrain (FB) samples revealed a virus dependent reduction of both Cx types 8 but not 4 weeks post infection (p.i.). Immunohistochemistry revealed an increase of Cx43 in the DG and a decrease in the CA3 region 4 and 8 weeks p.i. Cx30, which was detectable only 8 weeks p.i., revealed a BDV dependent increase in DG and CA3 regions. BDV dependent astrogliosis as revealed by immunodetection of glial fibrillary acidic protein (GFAP) correlated not with astroglial connexin expression. With regard to functional coupling as revealed by scrape loading, BDV infection resulted in increased spreading of the GJ permeant dye Lucifer yellow in primary hippocampal astroglial cultures, and in increased expression of Cx43 and Cx30 as revealed by immunocytochemistry. In conclusion, persistent BDV infection of the Lewis rat brain leads to changes in astroglial Cx expression both in vivo and in vitro and of functional coupling in vitro. Distribution and time course of these changes suggest them to be a direct result of neurodegeneration in the DG and an indirect effect of neuronal deafferentiation in the CA3 region. (c) 2007 Elsevier B.V. All rights reserved."],["dc.identifier.doi","10.1016/j.brainres.2007.09.062"],["dc.identifier.isi","000252096600036"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47413"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1872-6240"],["dc.relation.issn","0006-8993"],["dc.title","Persistent Borna Disease Virus infection changes expression and function of astroglial gap junctions in vivo and in vitro"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","163"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Molecular Neuroscience"],["dc.bibliographiccitation.lastpage","180"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Almamy, Abdullah"],["dc.contributor.author","Schwerk, C."],["dc.contributor.author","Schroten, Horst"],["dc.contributor.author","Ishikawa, Hiroshi"],["dc.contributor.author","Asif, Abdul Rahman"],["dc.contributor.author","Reuss, Bernhard"],["dc.date.accessioned","2018-11-07T10:23:14Z"],["dc.date.available","2018-11-07T10:23:14Z"],["dc.date.issued","2017"],["dc.description.abstract","Early maternal infections with Neisseria gonorrhoeae (NG) correlate to an increased lifetime schizophrenia risk for the offspring, which might be due to an immune-mediated mechanism. Here, we investigated the interactions of polyclonal antisera to NG (alpha-NG) with a first trimester prenatal brain multiprotein array, revealing among others the SNARE-complex protein Snap23 as a target antigen for alpha-NG. This interaction was confirmed by Western blot analysis with a recombinant Snap23 protein, whereas the closely related Snap25 failed to interact with alpha-NG. Furthermore, a polyclonal antiserum to the closely related bacterium Neisseria meningitidis (alpha-NM) failed to interact with both proteins. Functionally, in SH-SY5Y cells, alpha-NG pretreatment interfered with both insulin-induced vesicle recycling, as revealed by uptake of the fluorescent endocytosis marker FM1-43, and insulin-dependent membrane translocation of the glucose transporter GluT4. Similar effects could be observed for an antiserum raised directly to Snap23, whereas a serum to Snap25 failed to do so. In conclusion, Snap23 seems to be a possible immune target for anti-gonococcal antibodies, the interactions of which seem at least in vitro to interfere with vesicle-associated exocytosis. Whether these changes contribute to the correlation between maternal gonococcal infections and psychosis in vivo remains still to be clarified."],["dc.description.sponsorship","University Medicine Gottingen (UMG)"],["dc.identifier.doi","10.1007/s12031-017-0920-2"],["dc.identifier.isi","000402981900004"],["dc.identifier.pmid","28462458"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42420"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Humana Press Inc"],["dc.relation.issn","1559-1166"],["dc.relation.issn","0895-8696"],["dc.title","Crossreactivity of an Antiserum Directed to the Gram-Negative Bacterium Neisseria gonorrhoeae with the SNARE-Complex Protein Snap23 Correlates to Impaired Exocytosis in SH-SY5Y Cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]