Stephani, Caspar

[["dc.bibliographiccitation.firstpage","724"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","729"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Koubeissi, Mohamad Z."],["dc.date.accessioned","2018-11-07T09:55:14Z"],["dc.date.available","2018-11-07T09:55:14Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: The thresholds of current intensities required to evoke a clinical response during intracranial electrical stimulation mapping vary. Objective: We wanted to test if there is systematic variation of threshold currents between different brain areas. Methods: Electrode contacts of depth electrodes in a series of patients undergoing presurgical evaluation for epilepsy surgery were stimulated. The brain regions we studied included the insular cortex, the pericentral cortex, and the intervening white matter. Results: Current intensities that elicited clinical responses in central subcortical white matter tracts were significantly lower than those needed to evoke a clinical response in the cortex. Conclusion: We found systematic differences of threshold stimulation intensities between cortical and subcortical structures in the human brain. In addition to known neurophysiologic differences between white and grey matter, the systematic difference in stimulation thresholds may be due to the direction of the white matter tracts with respect to the electrode orientation and to inherent properties of specific brain regions. (C) 2015 Elsevier Inc. All rights reserved."],["dc.description.sponsorship","Stiftungsrat fur die deutsche Wissenschaft [S 134-10.044]"],["dc.identifier.doi","10.1016/j.brs.2015.02.011"],["dc.identifier.isi","000357542100006"],["dc.identifier.pmid","25842075"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36700"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1876-4754"],["dc.relation.issn","1935-861X"],["dc.title","Differences of Intracranial Electrical Stimulation Thresholds in the Human Brain"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","177"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","179"],["dc.bibliographiccitation.volume","86"],["dc.contributor.author","Koubeissi, Mohamad Z."],["dc.contributor.author","Vaca, Guadalupe Fernandez-Baca"],["dc.contributor.author","Maciunas, Robert"],["dc.contributor.author","Stephani, Caspar"],["dc.date.accessioned","2018-11-07T10:19:27Z"],["dc.date.available","2018-11-07T10:19:27Z"],["dc.date.issued","2016"],["dc.description.abstract","Objective:To investigate the effects of extraoperative electrical stimulation of fiber tracts connecting the language territories.Methods:We describe results of extraoperative electrical stimulation of stereotactic electrodes in 3 patients with epilepsy who underwent presurgical evaluation for epilepsy surgery. Contacts of these electrodes sampled, among other structures, the suprainsular white matter of the left hemisphere.Results:Aside from speech disturbance and speech arrest, subcortical electrical stimulation of white matter tracts directly superior to the insula representing the anterior part of the arcuate fascicle, reproducibly induced complex verbal auditory phenomena including (1) hearing one's own voice in the absence of overt speech, and (2) lack of perception of arrest or alteration in ongoing repetition of words.Conclusion:These results represent direct evidence that the anterior part of the arcuate fascicle is part of a network that is important in the mediation of speech planning and awareness likely by linking the language areas of the inferior parietal and posterior inferior frontal cortices. More specifically, our observations suggest that this structure may be relevant to the pathophysiology of thought disorders and auditory verbal hallucinations."],["dc.description.sponsorship","Stifterverband fur die Deutsche Wissenschaft [S134-10.044]"],["dc.identifier.doi","10.1212/WNL.0000000000002246"],["dc.identifier.isi","000368454800012"],["dc.identifier.pmid","26643545"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41658"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1526-632X"],["dc.relation.issn","0028-3878"],["dc.title","A white matter tract mediating awareness of speech"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","186"],["dc.bibliographiccitation.journal","Epilepsia"],["dc.bibliographiccitation.lastpage","187"],["dc.bibliographiccitation.volume","50"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Fernandez-Baca-Vaca, G."],["dc.contributor.author","Maciunas, Robert"],["dc.contributor.author","Koubeissi, Mohamad Z."],["dc.contributor.author","Lueders, Heike"],["dc.date.accessioned","2018-11-07T11:22:31Z"],["dc.date.available","2018-11-07T11:22:31Z"],["dc.date.issued","2009"],["dc.identifier.isi","000270550500390"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56011"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.publisher.place","Malden"],["dc.relation.conference","63rd Annual Meeting of the American-Epilepsy-Society"],["dc.relation.eventlocation","Boston, MA"],["dc.relation.issn","0013-9580"],["dc.title","FUNCTIONAL NEUROANATOMY OF THE INSULAR CORTEX"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Epilepsia"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Koubeissi, Mohamad Z."],["dc.date.accessioned","2018-11-07T09:06:23Z"],["dc.date.available","2018-11-07T09:06:23Z"],["dc.date.issued","2012"],["dc.format.extent","126"],["dc.identifier.isi","000308875900432"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25547"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","10th European Congress on Epileptology"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","0013-9580"],["dc.title","DIFFERENCES OF INTRACEREBRAL ELECTRICAL STIMULATION THRESHOLDS IN THE HUMAN BRAIN"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]