Song, Chen

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[["dc.bibliographiccitation.firstpage","s44"],["dc.bibliographiccitation.issue","a1"],["dc.bibliographiccitation.journal","Acta Crystallographica. Section A, Foundations and Advances"],["dc.bibliographiccitation.lastpage","s44"],["dc.bibliographiccitation.volume","71"],["dc.contributor.author","Gruene, Tim"],["dc.contributor.author","Hahn, Hinrich W."],["dc.contributor.author","Luebben, Anna V."],["dc.contributor.author","Meilleur, Flora"],["dc.contributor.author","Sheldrick, George M."],["dc.contributor.author","Köpfer, David A."],["dc.contributor.author","Song, Chen"],["dc.contributor.author","Zachariae, Ulrich"],["dc.contributor.author","de Groot, Bert L."],["dc.contributor.author","Luebben, Jens"],["dc.date.accessioned","2021-03-05T08:58:58Z"],["dc.date.available","2021-03-05T08:58:58Z"],["dc.date.issued","2015"],["dc.identifier.doi","10.1107/S2053273315099301"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80318"],["dc.notes.intern","DOI Import GROB-393"],["dc.relation.issn","2053-2733"],["dc.title","Xen crystallography - choose your radiation"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","118a"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.volume","108"],["dc.contributor.author","Zachariae, Ulrich"],["dc.contributor.author","Kopfer, David A."],["dc.contributor.author","Song, Chen"],["dc.contributor.author","Gruene, Tim"],["dc.contributor.author","Sheldrick, George M."],["dc.contributor.author","de Groot, Bert L."],["dc.date.accessioned","2018-11-07T10:01:55Z"],["dc.date.available","2018-11-07T10:01:55Z"],["dc.date.issued","2015"],["dc.format.extent","118A"],["dc.identifier.doi","10.1016/j.bpj.2014.11.663"],["dc.identifier.isi","000359471700591"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38130"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-393"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.publisher.place","Cambridge"],["dc.relation.issn","1542-0086"],["dc.relation.issn","0006-3495"],["dc.title","Ion Permeation in Potassium Channels Involves Direct Coulomb Knock-On between Ions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","129a"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Biophysical Journal"],["dc.bibliographiccitation.volume","108"],["dc.contributor.author","Song, Chen"],["dc.contributor.author","Gruene, Tim"],["dc.contributor.author","Sheldrick, George M."],["dc.contributor.author","Sansom, Mark S. P."],["dc.contributor.author","Zachariae, Ulrich"],["dc.contributor.author","de Groot, Bert L."],["dc.contributor.author","Köpfer, David A."],["dc.date.accessioned","2018-11-07T10:01:56Z"],["dc.date.available","2018-11-07T10:01:56Z"],["dc.date.issued","2015"],["dc.format.extent","129A"],["dc.identifier.doi","10.1016/j.bpj.2014.11.721"],["dc.identifier.isi","000359471700647"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38131"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-393"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.publisher.place","Cambridge"],["dc.relation.issn","1542-0086"],["dc.relation.issn","0006-3495"],["dc.title","Direct Contacts of K+ Ions in the Selectivity Filter Enable the High Conductance of K+ Channels"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","352"],["dc.bibliographiccitation.issue","6207"],["dc.bibliographiccitation.journal","Science"],["dc.bibliographiccitation.lastpage","355"],["dc.bibliographiccitation.volume","346"],["dc.contributor.author","Koepfer, David A."],["dc.contributor.author","Song, Chen"],["dc.contributor.author","Gruene, Tim"],["dc.contributor.author","Sheldrick, George M."],["dc.contributor.author","Zachariae, Ulrich"],["dc.contributor.author","de Groot, Bert L."],["dc.date.accessioned","2018-11-07T09:33:31Z"],["dc.date.available","2018-11-07T09:33:31Z"],["dc.date.issued","2014"],["dc.description.abstract","Potassium channels selectively conduct K+ ions across cellular membranes with extraordinary efficiency. Their selectivity filter exhibits four binding sites with approximately equal electron density in crystal structures with high K+ concentrations, previously thought to reflect a superposition of alternating ion-and water-occupied states. Consequently, cotranslocation of ions with water has become a widely accepted ion conduction mechanism for potassium channels. By analyzing more than 1300 permeation events from molecular dynamics simulations at physiological voltages, we observed instead that permeation occurs via ion-ion contacts between neighboring K+ ions. Coulomb repulsion between adjacent ions is found to be the key to high-efficiency K+ conduction. Crystallographic data are consistent with directly neighboring K+ ions in the selectivity filter, and our model offers an intuitive explanation for the high throughput rates of K+ channels."],["dc.identifier.doi","10.1126/science.1254840"],["dc.identifier.isi","000343041100045"],["dc.identifier.pmid","25324389"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31983"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Advancement Science"],["dc.relation.issn","1095-9203"],["dc.relation.issn","0036-8075"],["dc.title","Ion permeation in K+ channels occurs by direct Coulomb knock-on"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]