Banaschewski, Tobias

[["dc.bibliographiccitation.firstpage","1050"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Journal of the American Academy of Child & Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","1061"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Chen, Di"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Cheng, Wei"],["dc.contributor.author","Cao, Miao"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Bokde, Arun L.W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2022-10-04T10:21:15Z"],["dc.date.available","2022-10-04T10:21:15Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.jaac.2021.11.030"],["dc.identifier.pii","S0890856721020529"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114361"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-600"],["dc.relation.issn","0890-8567"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Brain Signatures During Reward Anticipation Predict Persistent Attention-Deficit/Hyperactivity Disorder Symptoms"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","JAMA psychiatry"],["dc.bibliographiccitation.volume","73"],["dc.contributor.author","Lancaster, Thomas M."],["dc.contributor.author","Linden, David E."],["dc.contributor.author","Tansey, Katherine E."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Cattrell, Anna"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Paillere Martinot, Marie-Laure"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Lemaitre, Herve"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Jurk, Sarah"],["dc.contributor.author","Mennigen, Eva"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2017-09-07T11:46:24Z"],["dc.date.available","2017-09-07T11:46:24Z"],["dc.date.issued","2016"],["dc.description.abstract","IMPORTANCE: Psychotic disorders are characterized by attenuated activity in the brain's valuation system in key reward processing areas, such as the ventral striatum (VS), as measured with functional magnetic resonance imaging.; OBJECTIVE: To examine whether common risk variants for psychosis are associated with individual variation in the VS.; DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional study of a large cohort of adolescents from the IMAGEN study (a European multicenter study of reinforcement sensitivity in adolescents) was performed from March 1, 2008, through December 31, 2011. Data analysis was conducted from October 1, 2015, to January 9, 2016. Polygenic risk profile scores (RPSs) for psychosis were generated for 1841 healthy adolescents. Sample size and characteristics varied across regression analyses, depending on mutual information available (N=1524-1836).; MAIN OUTCOMES AND MEASURES: Reward-related brain function was assessed with blood oxygen level dependency (BOLD) in the VS using the monetary incentive delay (MID) task, distinguishing reward anticipation and receipt. Behavioral impulsivity, IQ, MID task performance, and VS BOLD were regressed against psychosis RPS at 4 progressive P thresholds (P < .01, P < .05, P < .10, and P < .50 for RPS models 1-4, respectively).; RESULTS: In a sample of 1841 healthy adolescents (mean age, 14.5 years; 906 boys and 935 girls), we replicated an association between increasing psychosis RPS and reduced IQ (matrix reasoning: corrected P = .003 for RPS model 2, 0.4% variance explained), supporting the validity of the psychosis RPS models. We also found a nominally significant association between increased psychosis RPS and reduced MID task performance (uncorrected P =.03 for RPS model 4, 0.2% variance explained). Our main finding was a positive association between psychosis RPS and VS BOLD during reward anticipation at all 4 psychosis RPS models and for 2 P thresholds for reward receipt (RPS models 1 and 3), correcting for the familywise error rate (0.8%-1.9% variance explained).; CONCLUSIONS AND RELEVANCE: These findings support an association between psychosis RPS and VS BOLD in adolescents. Genetic risk for psychosis may shape an individual's response to rewarding stimuli."],["dc.identifier.doi","10.1001/jamapsychiatry.2016.1135"],["dc.identifier.gro","3151922"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8757"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","2168-6238"],["dc.title","Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1092"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Journal of the American Academy of Child and Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","1103"],["dc.bibliographiccitation.volume","58"],["dc.contributor.author","Spechler, Philip A."],["dc.contributor.author","Chaarani, Bader"],["dc.contributor.author","Orr, Catherine"],["dc.contributor.author","Mackey, Scott"],["dc.contributor.author","Higgins, Stephen T."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L.W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Althoff, Robert R."],["dc.contributor.author","Barker, Gareth"],["dc.contributor.author","Paillère Martinot, Marie-Laure"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Lemaitre, Herve"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Jurk, Sarah"],["dc.contributor.author","Mennigen, Eva"],["dc.date.accessioned","2020-12-10T14:24:42Z"],["dc.date.available","2020-12-10T14:24:42Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.jaac.2019.01.021"],["dc.identifier.issn","0890-8567"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72329"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Neuroimaging Evidence for Right Orbitofrontal Cortex Differences in Adolescents With Emotional and Behavioral Dysregulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1019"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","1028"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Barker, Edward D"],["dc.contributor.author","Ing, Alex"],["dc.contributor.author","Biondo, Francesca"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Pingault, Jean-Baptiste"],["dc.contributor.author","Du Rietz, Ebba"],["dc.contributor.author","Zhang, Yuning"],["dc.contributor.author","Ruggeri, Barbara"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Bokde, Arun L. W"],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Sounga-Barke, Edmund"],["dc.contributor.author","Bowling, April B."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Papadopoulos-Orfanos, Dimitri"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N"],["dc.contributor.author","Vetter, Nora C."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2021-04-14T08:28:41Z"],["dc.date.available","2021-04-14T08:28:41Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1038/s41380-019-0444-y"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82679"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.title","Do ADHD-impulsivity and BMI have shared polygenic and neural correlates?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European child & adolescent psychiatry"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Bartholdy, Savani"],["dc.contributor.author","Allen, Karina"],["dc.contributor.author","Hodsoll, John"],["dc.contributor.author","O'Daly, O. G."],["dc.contributor.author","Campbell, Iain C."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Mennigen, Eva"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Schmidt, Ulrike"],["dc.date.accessioned","2017-09-07T11:52:08Z"],["dc.date.available","2017-09-07T11:52:08Z"],["dc.date.issued","2017"],["dc.description.abstract","This study investigated the prevalence of disordered eating cognitions and behaviours across mid-adolescence in a large European sample, and explored the extent to which prevalence ratings were affected by informant (parent/adolescent), or the sex or age of the adolescent. The Development and Well-Being Assessment was completed by parent-adolescent dyads at age 14 (n=2225) and again at age 16 (n=1607) to explore the prevalence of 7 eating disorder symptoms (binge eating, purging, fear of weight gain, distress over shape/weight, avoidance of fattening foods, food restriction, and exercise for weight loss). Informant agreement was assessed using kappa coefficients. Generalised estimating equations were performed to explore the impact of age, sex and informant on symptom prevalence. Slight to fair agreement was observed between parent and adolescent reports (kappa estimates between 0.045 and 0.318); however, this was largely driven by agreement on the absence of behaviours. Disordered eating behaviours were more consistently endorsed amongst girls compared to boys (odds ratios: 2.96-5.90) and by adolescents compared to their parents (odds ratios: 2.71-9.05). Our data are consistent with previous findings in epidemiological studies. The findings suggest that sex-related differences in the prevalence of disordered eating behaviour are established by mid-adolescence. The greater prevalence rates obtained from adolescent compared to parent reports may be due to the secretive nature of the behaviours and/or lack of awareness by parents. If adolescent reports are overlooked, the disordered behaviour may have a greater opportunity to become more entrenched."],["dc.identifier.doi","10.1007/s00787-016-0935-1"],["dc.identifier.gro","3151180"],["dc.identifier.pmid","28050706"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7956"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1435-165X"],["dc.subject","Parent; Adolescent; Epidemiology; Eating disorders"],["dc.title","Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2648"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Molecular Psychiatry"],["dc.bibliographiccitation.lastpage","2671"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Mascarell Maričić, Lea"],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Rosenthal, Annika"],["dc.contributor.author","Ripke, Stephan"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Itterman, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Kaminski, Jakob"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Heinz, Andreas"],["dc.date.accessioned","2021-04-14T08:25:50Z"],["dc.date.available","2021-04-14T08:25:50Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41380-020-0822-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81743"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1476-5578"],["dc.relation.issn","1359-4184"],["dc.title","The IMAGEN study: a decade of imaging genetics in adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","544"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Nature Human Behaviour"],["dc.bibliographiccitation.lastpage","558"],["dc.bibliographiccitation.volume","4"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Ing, Alex"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Tay, Nicole"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Francesca, Biondo"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Feng, Jianfeng"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Grigis, Antoine"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.date.accessioned","2021-04-14T08:26:46Z"],["dc.date.available","2021-04-14T08:26:46Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41562-020-0846-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82071"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2397-3374"],["dc.title","Neurobehavioural characterisation and stratification of reinforcement-related behaviour"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","844"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","American Journal of Psychiatry"],["dc.bibliographiccitation.lastpage","854"],["dc.bibliographiccitation.volume","177"],["dc.contributor.author","Shen, Chun"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Zhao, Qi"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Quinlan, Erin Burke"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Millenet, Sabina"],["dc.contributor.author","Bokde, Arun L.W."],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Artiges, Eric"],["dc.contributor.author","Paillère-Martinot, Marie-Laure"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Papadopoulos Orfanos, Dimitri"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Li, Fei"],["dc.contributor.author","Feng, Jianfeng"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Sahakian, Barbara J."],["dc.date.accessioned","2021-04-14T08:32:48Z"],["dc.date.available","2021-04-14T08:32:48Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1176/appi.ajp.2020.19020183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84024"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1535-7228"],["dc.relation.issn","0002-953X"],["dc.title","Neural Correlates of the Dual-Pathway Model for ADHD in Adolescents"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","436"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of the American Academy of Child and Adolescent Psychiatry"],["dc.bibliographiccitation.lastpage","444"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Xu, Bing"],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Macare, Christine"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Cattrell, Anna"],["dc.contributor.author","Conrod, Patricia J."],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Gallinat, Jürgen"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Paus, Tomáš"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Desrivières, Sylvane"],["dc.date.accessioned","2017-09-07T11:52:07Z"],["dc.date.available","2017-09-07T11:52:07Z"],["dc.date.issued","2017"],["dc.description.abstract","Objective:In a recent genomewide association study of subcortical brain volumes, a common genetic variation at rs945270 was identified as having the strongest effect on putamen volume, a brain measurement linked to familial risk for attention-deficit/hyperactivity disorder (ADHD). To determine whether rs945270 might be a genetic determinant of ADHD, its effects on ADHD-related symptoms and neural mechanisms of ADHD, such as response inhibition and reward sensitivity, were explored.Method:A large population sample of 1,834 14-year-old adolescents was used to test the effects of rs945270 on ADHD symptoms assessed through the Strengths and Difficulties Questionnaire and region-of-interest analyses of putamen activation by functional magnetic resonance imaging using the stop signal and monetary incentive delay tasks, assessing response inhibition and reward sensitivity, respectively.Results:There was a significant link between rs945270 and ADHD symptom scores, with the C allele associated with lower symptom scores, most notably hyperactivity. In addition, there were sex-specific effects of this variant on the brain. In boys, the C allele was associated with lower putamen activity during successful response inhibition, a brain response that was not associated with ADHD symptoms. In girls, putamen activation during reward anticipation increased with the number of C alleles, most significantly in the right putamen. Remarkably, right putamen activation during reward anticipation tended to negatively correlate with ADHD symptoms.Conclusion:These results indicate that rs945270 might contribute to the genetic risk of ADHD partly through its effects on hyperactivity and reward processing in girls."],["dc.identifier.doi","10.1016/j.jaac.2017.02.009"],["dc.identifier.gro","3151184"],["dc.identifier.pmid","28433093"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7960"],["dc.language.iso","en"],["dc.notes.intern","WoS Import 2017-07-25"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.relation.issn","1527-5418"],["dc.subject","rs945270; putamen; attention-deficit/hyperactivity disorder; reward anticipation; response control"],["dc.title","Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Medicine"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Luo, Qiang"],["dc.contributor.author","Zhang, Lingli"],["dc.contributor.author","Huang, Chu-Chung"],["dc.contributor.author","Zheng, Yan"],["dc.contributor.author","Kanen, Jonathan W."],["dc.contributor.author","Zhao, Qi"],["dc.contributor.author","Yao, Ye"],["dc.contributor.author","Quinlan, Erin B."],["dc.contributor.author","Jia, Tianye"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Bokde, Arun L. W."],["dc.contributor.author","Bromberg, Uli"],["dc.contributor.author","Büchel, Christian"],["dc.contributor.author","Flor, Herta"],["dc.contributor.author","Frouin, Vincent"],["dc.contributor.author","Garavan, Hugh"],["dc.contributor.author","Gowland, Penny"],["dc.contributor.author","Heinz, Andreas"],["dc.contributor.author","Ittermann, Bernd"],["dc.contributor.author","Martinot, Jean-Luc"],["dc.contributor.author","Martinot, Marie-Laure Paillère"],["dc.contributor.author","Nees, Frauke"],["dc.contributor.author","Orfanos, Dimitri Papadopoulos"],["dc.contributor.author","Poustka, Luise"],["dc.contributor.author","Hohmann, Sarah"],["dc.contributor.author","Fröhner, Juliane H."],["dc.contributor.author","Smolka, Michael N."],["dc.contributor.author","Walter, Henrik"],["dc.contributor.author","Whelan, Robert"],["dc.contributor.author","Sahakian, Barbara J."],["dc.contributor.author","Schumann, Gunter"],["dc.contributor.author","Li, Fei"],["dc.contributor.author","Feng, Jianfeng"],["dc.contributor.author","Desrivières, Sylvane"],["dc.contributor.author","Robbins, Trevor W."],["dc.date.accessioned","2021-04-14T08:31:20Z"],["dc.date.available","2021-04-14T08:31:20Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1186/s12916-020-01743-2"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83560"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1741-7015"],["dc.title","Association between childhood trauma and risk for obesity: a putative neurocognitive developmental pathway"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]