Banaschewski, Tobias

[["dc.bibliographiccitation.firstpage","53"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Psychopathology"],["dc.bibliographiccitation.lastpage","59"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Holtmann, Martin"],["dc.contributor.author","Becker, Andreas"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Roessner, Veit"],["dc.date.accessioned","2018-11-07T09:01:59Z"],["dc.date.available","2018-11-07T09:01:59Z"],["dc.date.issued","2011"],["dc.description.abstract","Background: In many severely mentally disordered children, the clinical presentation is complicated by comorbid affective and behavioral dysregulation. Recently, a highly heritable behavioral phenotype of simultaneous deviance on the nanxious/depressed, attention problems, and aggressive behavior syndrome scales has been identified on the Child Behavior Checklist Dysregulation Profile (CBCL-DP). The aim of the present pilot study was to determine an equivalent to the CBCL-DP using the Strengths and Difficulties Questionnaire (SDQ). Sampling and Methods: We applied stepwise linear discriminant analyses and receiver operating characteristic (ROC) analysis to data from 543 consecutively referred children and adolescents, aged 5-17 years. The CBCL and the SDQ were completed by parents as part of the diagnostic routine. ICD-10 discharge diagnoses were established in consensus conferences. Results: A combination of five SDQ items (SDQ-Dysregulation Profile, SDQ-DP) yielded the best discrimination of children with and without CBCL-DP and classified 81.0% of the subjects correctly leading to an area under the curve of 0.93. The content of the five SDQ-DP items mirrors well the mixed behavioral phenotype of anxious-depressive, aggressive and attention problems captured by the CBCL-DP. SDQ-DP status was highly correlated with CBCL-DP status and was best defined by a SDQ-DP score >= 5. Conclusions: The psychometric properties of the SDQ-DP have been robustly tested and validated. Based on these results, clinicians may use the SDQ-DP as a useful and economical screening measure to improve the assessment, prevention, and treatment of severe dysregulation in childhood and adolescence. Future investigations should study the longitudinal stability, heritability, and genetic associations of this behavioral phenotype. Copyright (C) 2010 S. Karger AG, Basel"],["dc.identifier.doi","10.1159/000318164"],["dc.identifier.isi","000284157300008"],["dc.identifier.pmid","21072000"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8050"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24567"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","0254-4962"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Psychometric Validity of the Strengths and Difficulties Questionnaire-Dysregulation Profile"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","1060"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Becker, Andreas"],["dc.contributor.author","Buse, Judith"],["dc.contributor.author","Wanderer, Sina"],["dc.contributor.author","Buitelaar, J. K."],["dc.contributor.author","Sergeant, Joseph A."],["dc.contributor.author","Sonuga-Barke, Edmund J."],["dc.contributor.author","Gill, Michael"],["dc.contributor.author","Manor, Iris"],["dc.contributor.author","Miranda, Ana"],["dc.contributor.author","Mulas, Fernando"],["dc.contributor.author","Oades, Robert D."],["dc.contributor.author","Roeyers, Herbert"],["dc.contributor.author","Steinhausen, Hans-Christoph"],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Asherson, Philip"],["dc.contributor.author","Rothenberger, Aribert"],["dc.date.accessioned","2018-11-07T10:11:32Z"],["dc.date.available","2018-11-07T10:11:32Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: The association of attention-deficit/hyperactivity disorder (ADHD) and tic disorder (TD) is frequent and clinically important. Very few and inconclusive attempts have been made to clarify if and how the combination of ADHD-FTD runs in families. Aim: To determine the first time in a large-scale ADHD sample whether ADHD-FTD increases the risk of ADHDH+TD in siblings and, also the first time, if this is independent of their psychopathological vulnerability in general. Methods: The study is based on the International Multicenter ADHD Genetics (IMAGE) study. The present sub-sample of 2815 individuals included ADHD-index patients with co-existing TD (ADHD-FTD, n = 262) and without TD (ADHD+TD, n = 947) as well as their 1606 full siblings (n = 358 of the ADHDH+TD index patients and n = 1248 of the ADHD-TD index patients). We assessed psychopathological symptoms in index patients and siblings by using the Strength and Difficulties Questionnaire (SDQ) and the parent and teacher Conners' long version Rating Scales (CRS). For disorder classification the Parental Account of Childhood Symptoms (PACS-Interview) was applied in n = 271 children. Odds ratio with the GENMOD procedure (PROCGENMOD) was used to test if the risk for ADHD, TD, and ADHD-FTD in siblings was associated with the related index patients' diagnoses. In order to get an estimate for specificity we compared the four groups for general psychopathological symptoms. Results: Co-existing ADHD-FTD in index patients increased the risk of both comorbid ADHD-FTD and TD in the siblings of these index patients. These effects did not extend to general psychopathology. Interpretation: Co-existence of ADHD+FTD may segregate in families. The same holds true for TD (without ADHD). Hence, the segregation of TD (included in both groups) seems to be the determining factor, independent of further behavioral problems. This close relationship between ADHD and TD supports the clinical approach to carefully assess ADHD in any case of TD."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2016"],["dc.identifier.doi","10.3389/fpsyg.2016.01060"],["dc.identifier.isi","000379876400001"],["dc.identifier.pmid","27486412"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40067"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Frontiers Media Sa"],["dc.relation.issn","1664-1078"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Familiality of Co-existing ADHD and Tic Disorders: Evidence from a Large Sibling Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0178866"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Uebel-von Sandersleben, Henrik"],["dc.contributor.author","Albrecht, Bjorn"],["dc.contributor.author","Rothenberger, Aribert"],["dc.contributor.author","Fillmer-Heise, Anke"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Sergeant, Joseph"],["dc.contributor.author","Tannock, Rosemary"],["dc.contributor.author","Banaschewski, Tobias"],["dc.date.accessioned","2018-11-07T10:22:46Z"],["dc.date.available","2018-11-07T10:22:46Z"],["dc.date.issued","2017"],["dc.description.abstract","Objective Attention Deficit / Hyperactivity Disorder (ADHD) and Chronic Tic Disorder (CTD) are two common and frequently co-existing disorders, probably following an additive model. But this is not yet clear for the basic sensory function of colour processing sensitive to dopaminergic functioning in the retina and higher cognitive functions like attention and interference control. The latter two reflect important aspects for psychoeducation and behavioural treatment approaches. Methods Colour discrimination using the Farnsworth-Munsell 100-hue Test, sustained attention during the Frankfurt Attention Inventory (FAIR), and interference liability during Colour- and Counting-Stroop-Tests were assessed to further clarify the cognitive profile of the co-existence of ADHD and CTD. Altogether 69 children were classified into four groups: ADHD (N = 14), CTD (N = 20), ADHD+CTD (N = 20) and healthy Controls (N = 15) and compared in cognitive functioning in a 2x2-factorial statistical model. Results Difficulties with colour discrimination were associated with both ADHD and CTD factors following an additive model, but in ADHD these difficulties tended to be more pronounced on the blue-yellow axis. Attention problems were characteristic for ADHD but not CTD. Interference load was significant in both Colour-and Counting-Stroop-Tests and unrelated to colour discrimination. Compared to Controls, interference load in the Colour-Stroop was higher in pure ADHD and in pure CTD, but not in ADHD+CTD, following a sub-additive model. In contrast, interference load in the Counting-Stroop did not reveal ADHD or CTD effects. Conclusion The co-existence of ADHD and CTD is characterized by additive as well as sub-additive performance impairments, suggesting that their co-existence may show simple additive characteristics of both disorders or a more complex interaction, depending on demand. The equivocal findings on interference control may indicate limited validity of the Stroop-Paradigm for clinical assessments."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2017"],["dc.identifier.doi","10.1371/journal.pone.0178866"],["dc.identifier.isi","000402923200058"],["dc.identifier.pmid","28594866"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14557"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42336"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Revisiting the co-existence of Attention-Deficit/Hyperactivity Disorder and Chronic Tic Disorder in childhood-The case of colour discrimination, sustained attention and interference control"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]