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Terney, Daniella
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Terney, Daniella
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Terney, Daniella
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Terney, D.
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2007Journal Article [["dc.bibliographiccitation.firstpage","2687"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","European Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","2691"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Poreisz, Csaba"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:56:23Z"],["dc.date.available","2018-11-07T10:56:23Z"],["dc.date.issued","2007"],["dc.description.abstract","Stimulation with weak electrical direct currents has been shown to be capable of inducing stimulation-polarity-dependent prolonged diminutions or elevations of cortical excitability, most probably elicited by a hyper- or depolarization of resting membrane potentials. The aim of the present study was to test if cognitive task and motor exercise practiced during the stimulation are able to modify transcranial direct current stimulation-induced plasticity in the left primary motor cortex in 12 healthy subjects. Motor evoked potentials were recorded before and after 10 min of anodal and cathodal transcranial direct current stimulation. In Experiment 1, subjects were required to sit passively during the stimulation, in Experiment 2 the subject's attention was directed towards a cognitive test and in Experiment 3 subjects were instructed to push a ball in their right hand. Both the cognitive task and motor exercise modified transcranial direct current stimulation-induced plasticity; when performing the cognitive task during stimulation the motor cortex excitability was lower after anodal stimulation and higher after cathodal stimulation, compared with the passive condition. When performing the motor exercise, the motor cortex excitability was lower after both anodal and cathodal stimulation, compared with the passive condition. Our results show that transcranial direct current stimulation-induced plasticity is highly dependent on the state of the subject during stimulation."],["dc.identifier.doi","10.1111/j.1460-9568.2007.05896.x"],["dc.identifier.isi","000250645600028"],["dc.identifier.pmid","17970738"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50002"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.relation.issn","0953-816X"],["dc.title","Towards unravelling task-related modulations of neuroplastic changes induced in the human motor cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2008Journal Article [["dc.bibliographiccitation.firstpage","97"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Brain Stimulation"],["dc.bibliographiccitation.lastpage","105"],["dc.bibliographiccitation.volume","1"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Boros, Klara"],["dc.contributor.author","Poreisz, Csaba"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:16:21Z"],["dc.date.available","2018-11-07T11:16:21Z"],["dc.date.issued","2008"],["dc.description.abstract","Objective Inteference with brain rhythms by noninvasive transcranial stimulation that uses weak transcranial alternating current may reveal itself to be a new tool for investigating cortical mechanisms currently unresolved. Here. we aim to extend transcranial direct current stimulation (tDCS) techniques to transcranial alternating Current stimulation (tACS). Background Parameters such as electrode size and position were taken from those used ill Previous tDCS Studies. Methods Motor evoked potentials (MEPs) revealed by transcranial magnetic stimulation (TMS), electroencephalogram (EEG)-power, and reaction times measured in a motor implicit learning task, were analyzed to detect changes in cortical excitability after 2-10 minutes of AC stimulation and sinusoidal DC stimulation (tSDCS) by using 1, W, 15, 30, and 45 Hz and sham stimulation over the primary motor cortex in 50 healthy subjects (eight-16 subjects in each study). Results A significantly improved implicit motor learning was observed after 10 Hz AC stimulation only. No significant changes were observed in any of the analyzed frequency bands of EEG and with regard to the MEP amplitudes after AC or tSDCS stimulation. Similarly, if the anodal or cathodal DC stimulation was superimposed on 5, 10, and 15 Hz AC stimulation, the MEP amplitudes did not change significantly. Conclusions Transcranial application of weak AC current may appear to be a tool for basic and clinical research in diseases with altered EEG activity. However, its effect seems to be weaker than tDCS stimulation, at in the present context of stimulus intensity and duration. Further studies are required to extend cautiously the safety range and uncover its influence on neuronal circuitries. (C) 2008 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.brs.2007.10.001"],["dc.identifier.isi","000262716600008"],["dc.identifier.pmid","20633376"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54566"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1935-861X"],["dc.title","Comparatively weak after-effects of transcranial alternating current stimulation (tACS) on cortical excitability in humans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2008Journal Article [["dc.bibliographiccitation.firstpage","79"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Pain and Symptom Management"],["dc.bibliographiccitation.lastpage","91"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Bergmann, Inga"],["dc.contributor.author","Poreisz, Csaba"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Boros, Klara"],["dc.contributor.author","Nitsche, Michael Andreas"],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Antal, Andrea"],["dc.date.accessioned","2018-11-07T11:13:38Z"],["dc.date.available","2018-11-07T11:13:38Z"],["dc.date.issued","2008"],["dc.description.abstract","Transcranial direct current stimulation (tDCS) was recently reintroduced as a tool for inducing relatively long-lasting changes in cortical excitability in focal brain regions. Anodal stimulation over the primary motor cortex enhances cortical excitability, whereas cathodal stimulation decreases it. Prior studies have shown that enhancement of D2 receptor activity by pergolide consolidates tDCS-generated excitability diminution for up to 24 hours and that cathodal stimulation of the primary motor cortex diminishes experimentally induced pain sensation and reduces the N2-P2 amplitude of laser-evoked potentials immediately poststimulation. In the present study, we investigated the effect of pergolide and cathodal tDCS over the primary motor cortex on laser-evoked potentials and acute pain perception induced with a Tm:YAG laser in a double-blind, randomized, placebo-con trolled, crossover study. The amplitude changes of laser-evoked potentials and subjective pain rating scores of 12 healthy subjects were analyzed prior to and following 15 minutes cathodal tDCS combined with pergolide or placebo intake at five different time points. Our results indicate that the amplitude of the N2 component was significantly reduced following cathodal tDCS for up to two hours. Additionally, pergolide prolonged the effect of the cathodal tDCS for up to 24 hours, and a significantly lowered Pain sensation was observed for up to 40 minutes. Our study is a further step toward clinical application of cathodal tDCS over the primary motor cortex using pharmacological intervention to prolong the excitability-diminishing effect on pain perception for up to 24 hours poststimulation. Furthermore, it demonstrates the potential for repetitive daily stimulation therapy for pain patients."],["dc.identifier.doi","10.1016/j.jpainsymman.2007.08.014"],["dc.identifier.isi","000257688400009"],["dc.identifier.pmid","18358692"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53942"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0885-3924"],["dc.title","Pergolide increases the efficacy of cathodal direct current stimulation to reduce the amplitude of laser-evoked potentials in humans"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS