Now showing 1 - 3 of 3
  • 2012Journal Article
    [["dc.bibliographiccitation.artnumber","67"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Frontiers in Psychiatry"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Antal, A."],["dc.contributor.author","Terney, D."],["dc.contributor.author","Paulus, W."],["dc.date.accessioned","2019-07-09T11:53:38Z"],["dc.date.available","2019-07-09T11:53:38Z"],["dc.date.issued","2012"],["dc.description.abstract","Combined administration of transcranial direct current-stimulation (tDCS) with either pergolide (PER) or D-cycloserine (D-CYC) can prolong the excitability-diminishing effects of cathodal, or the excitability enhancing effect of anodal stimulation for up to 24 h poststimulation. However, it remains unclear whether the potentiation of the observed aftereffects is dominated just by the polarity and duration of the stimulation, or the dual application of combined stimulation and drug administration. The present study looks at whether the aftereffects of oral administration of PER (a D1/D2 agonist) or D-CYC (a partial NMDA receptor agonist), in conjunction with the short-duration antagonistic application of tDCS (either 5 min cathodal followed immediately by 5 min anodal or vice versa), that alone only induces short-lasting aftereffects, can modulate cortical excitability in healthy human subjects, as revealed by a single-pulse MEP (motor-evoked-potential) paradigm. Results indicate that the antagonistic application of tDCS induces short-term neuroplastic aftereffects that are dependent upon the order of the application of short-duration stimulation. The administration of D-CYC resulted in a marked inhibition of cortical excitability under the application of tDCS in both stimulation orders. Intake of PER resulted in an increase in cortical excitability in both stimulation orientations, but was non-significant compared to the placebo condition. These results indicate that the aftereffects of tDCS are dependent upon the order of stimulation applied, and also demonstrate the prolongation of tDCS aftereffects when combined with the administration of CNS active drugs."],["dc.identifier.doi","10.3389/fpsyt.2012.00067"],["dc.identifier.fs","588338"],["dc.identifier.pmid","22783210"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7844"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60469"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Frontiers Research Foundation"],["dc.relation.eissn","1664-0640"],["dc.rights","CC BY-NC 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/3.0"],["dc.title","Pharmacological Modulation of the Short-Lasting Effects of Antagonistic Direct Current-Stimulation Over the Human Motor Cortex"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC
  • 2008Journal Article
    [["dc.bibliographiccitation.firstpage","14147"],["dc.bibliographiccitation.issue","52"],["dc.bibliographiccitation.journal","Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","14155"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Chaieb, Leila"],["dc.contributor.author","Moliadze, Vera"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T11:07:51Z"],["dc.date.available","2018-11-07T11:07:51Z"],["dc.date.issued","2008"],["dc.description.abstract","For > 20 years, noninvasive transcranial stimulation techniques like repetitive transcranial magnetic stimulation (rTMS) and direct current stimulation (tDCS) have been used to induce neuroplastic-like effects in the human cortex, leading to the activity-dependent modification of synaptic transmission. Here, we introduce a novel method of electrical stimulation: transcranial random noise stimulation (tRNS), whereby a random electrical oscillation spectrum is applied over the motor cortex. tRNS induces consistent excitability increases lasting 60 min after stimulation. These effects have been observed in 80 subjects through both physiological measures and behavioral tasks. Higher frequencies (100-640 Hz) appear to be responsible for generating this excitability increase, an effect that may be attributed to the repeated opening of Na(+) channels. In terms of efficacy tRNS appears to possess at least the same therapeutic potential as rTMS/tDCS in diseases such as depression, while furthermore avoiding the constraint of current flow direction sensitivity characteristic of tDCS."],["dc.identifier.doi","10.1523/JNEUROSCI.4248-08.2008"],["dc.identifier.isi","000261985900014"],["dc.identifier.pmid","19109497"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6239"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52675"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Soc Neuroscience"],["dc.relation.issn","0270-6474"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Increasing Human Brain Excitability by Transcranial High-Frequency Random Noise Stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI PMID PMC WOS
  • 2017Journal Article
    [["dc.bibliographiccitation.journal","Frontiers in Behavioral Neuroscience"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Shirota, Yuichiro"],["dc.contributor.author","Terney, Daniella"],["dc.contributor.author","Antal, Andrea"],["dc.contributor.author","Paulus, Walter"],["dc.date.accessioned","2020-12-10T18:44:30Z"],["dc.date.available","2020-12-10T18:44:30Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3389/fnbeh.2017.00169"],["dc.identifier.eissn","1662-5153"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17008"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78479"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Influence of Concurrent Finger Movements on Transcranial Direct Current Stimulation (tDCS)-Induced Aftereffects"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
    Details DOI