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Harden, Markus
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Harden, Markus
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Harden, Markus
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Harden, M.
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2016Journal Article [["dc.bibliographiccitation.firstpage","3869"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Knee Surgery, Sports Traumatology, Arthroscopy"],["dc.bibliographiccitation.lastpage","3877"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Balcarek, Peter"],["dc.contributor.author","Rehn, Stephan"],["dc.contributor.author","Howells, Nick R."],["dc.contributor.author","Eldridge, Jonathan D."],["dc.contributor.author","Kita, Keisuke"],["dc.contributor.author","Dejour, David"],["dc.contributor.author","Nelitz, Manfred"],["dc.contributor.author","Banke, Ingo J."],["dc.contributor.author","Lambrecht, Delphine"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2020-12-10T14:09:50Z"],["dc.date.available","2020-12-10T14:09:50Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1007/s00167-016-4365-x"],["dc.identifier.eissn","1433-7347"],["dc.identifier.issn","0942-2056"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70574"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Results of medial patellofemoral ligament reconstruction compared with trochleoplasty plus individual extensor apparatus balancing in patellar instability caused by severe trochlear dysplasia: a systematic review and meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2016Journal Article [["dc.bibliographiccitation.firstpage","282"],["dc.bibliographiccitation.journal","Journal of Clinical Anesthesia"],["dc.bibliographiccitation.lastpage","289"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Wetz, Anna J."],["dc.contributor.author","Perl, Thorsten"],["dc.contributor.author","Brandes, Ivo Florian"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Bauer, Martin"],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T10:06:45Z"],["dc.date.available","2018-11-07T10:06:45Z"],["dc.date.issued","2016"],["dc.description.abstract","Study objective: Perioperative hypothermia is a frequently observed phenomenon of general anesthesia and is associated with adverse patient outcome. Recently, a significant influence of core temperature before induction of anesthesia has been reported. However, there are still little existing data on core temperature before induction of anesthesia and no data regarding potential risk factors for developing preoperative hypothermia. The purpose of this investigation was to estimate the incidence of hypothermia before anesthesia and to determine if certain factors predict its incidence. Design/setting/patients: Data from 7 prospective studies investigating core temperature previously initiated at our department were analyzed. Patients undergoing a variety of elective surgical procedures were included. Interventions/measurements: Core temperature was measured before induction of anesthesia with an oral (314 patients), infrared tympanic (143 patients), or tympanic contact thermometer (36 patients). Available potential predictors included American Society of Anesthesiologists status, sex, age, weight, height, body mass index, adipose ratio, and lean body weight. Association with preoperative hypothermia was assessed separately for each predictor using logistic regression. Independent predictors were identified using multivariable logistic regression. Main results: A total of 493 patients were included in the study. Hypothermia was found in 105 patients (21.3%; 95% confidence interval, 17.8%-25.2%). The median core temperature was 36.3 degrees C (25th-75th percentiles, 36.0 degrees C-36.7 degrees C). Two independent factors for preoperative hypothermia were identified: male sex and age (>52 years). Conclusions: As a consequence of the high incidence of hypothermia before anesthesia, measuring core temperature should be mandatory 60 to 120 minutes before induction to identify and provide adequate treatment to hypothermic patients. (C) 2016 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.jclinane.2016.03.065"],["dc.identifier.isi","000384952700058"],["dc.identifier.pmid","27687393"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39155"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1873-4529"],["dc.relation.issn","0952-8180"],["dc.title","Unexpectedly high incidence of hypothermia before induction of anesthesia in elective surgical patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2019Journal Article [["dc.bibliographiccitation.firstpage","1344"],["dc.bibliographiccitation.issue","10206"],["dc.bibliographiccitation.journal","The Lancet"],["dc.bibliographiccitation.lastpage","1351"],["dc.bibliographiccitation.volume","394"],["dc.contributor.author","Bauer, Axel"],["dc.contributor.author","Klemm, Mathias"],["dc.contributor.author","Rizas, Konstantinos D"],["dc.contributor.author","Hamm, Wolfgang"],["dc.contributor.author","von Stülpnagel, Lukas"],["dc.contributor.author","Dommasch, Michael"],["dc.contributor.author","Steger, Alexander"],["dc.contributor.author","Lubinski, Andrezej"],["dc.contributor.author","Flevari, Panagiota"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Platonov, Pyotr"],["dc.date.accessioned","2020-12-10T15:21:55Z"],["dc.date.available","2020-12-10T15:21:55Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/S0140-6736(19)31996-8"],["dc.identifier.issn","0140-6736"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73216"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prediction of mortality benefit based on periodic repolarisation dynamics in patients undergoing prophylactic implantation of a defibrillator: a prospective, controlled, multicentre cohort study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2015Journal Article [["dc.bibliographiccitation.firstpage","1209"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","The Journal of Clinical Psychiatry"],["dc.bibliographiccitation.lastpage","1215"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Krasnianski, Anna"],["dc.contributor.author","Bohling, Geeske T."],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Zerr, Inga"],["dc.date.accessioned","2018-11-07T09:52:06Z"],["dc.date.available","2018-11-07T09:52:06Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Psychiatric symptoms in sporadic Creutzfeldt-Jakob disease (sCJD) are still not sufficiently evaluated. Aim: To describe psychiatric symptoms in sCJD with respect to molecular subtype. Method: Patients in this retrospective study were classified according to established diagnostic criteria. 248 sCJD patients with known molecular subtype were recruited from January 1993 to December 2004 and investigated. Psychiatric symptoms were defined according to Mller and colleagues and the AMDP system (Study Group for Methods and Documentation in Psychiatry) and were collected by direct examination by study physicians or extracted from medical documentation. Our data were compared with published data on variant CJD (vCJD). Results: Psychiatric symptoms were common in sCJD patients (90%) and mostly found already at the disease onset (agitation in 64% of the patients, hallucinations in 45%, anxiety in 50%, depression in 37%). All psychiatric symptoms but illusions were found early in the disease course. Psychiatric symptoms in sCJD were less frequent than in vCJD. Conclusions: We provide the first detailed analysis of psychiatric symptoms in a large group of patients with sCJD with respect to differences concerning frequency and time point of occurrence of psychiatric symptoms between molecular subtypes. These data suggest that psychiatric symptoms occurring early in the disease course are common not only in vCJD but also in other CJD types."],["dc.identifier.doi","10.4088/JCP.13m08915"],["dc.identifier.isi","000365412500029"],["dc.identifier.pmid","25938948"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36044"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Physicians Postgraduate Press"],["dc.relation.issn","1555-2101"],["dc.relation.issn","0160-6689"],["dc.title","Psychiatric Symptoms in Patients With Sporadic Creutzfeldt-Jakob Disease in Germany"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2016Review [["dc.bibliographiccitation.firstpage","2160"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Pain"],["dc.bibliographiccitation.lastpage","2172"],["dc.bibliographiccitation.volume","157"],["dc.contributor.author","Straube, Sebastian"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Schroeder, Heiko"],["dc.contributor.author","Arendacka, Barbora"],["dc.contributor.author","Fan, Xiangning"],["dc.contributor.author","Moore, R. Andrew"],["dc.contributor.author","Friede, Tim"],["dc.date.accessioned","2018-11-07T10:07:45Z"],["dc.date.available","2018-11-07T10:07:45Z"],["dc.date.issued","2016"],["dc.description.abstract","Back schools are interventions that comprise exercise and education components. We aimed to systematically review the randomized controlled trial evidence on back schools for the treatment of chronic low back pain. By searching MEDLINE, Embase, and Cochrane Central as well as bibliographies, we identified 31 studies for inclusion in our systematic review and 5 of these for inclusion in meta-analyses. Meta-analyses for pain scores and functional outcomes revealed statistical superiority of back schools vs no intervention for some comparisons but not others. No meta-analysis was feasible for the comparison of back schools vs other active treatments. Adverse events were poorly reported so that no reliable conclusions regarding the safety of back schools can be drawn, although some limited reassurance in this regard may be derived from the fact that few adverse events and no serious adverse events were reported in the back school groups in the studies that did report on safety. Overall, the evidence base for the use of back schools to treat chronic low back pain is weak; in nearly a half-century since back schools were first trialled, no unequivocal evidence of benefit has emerged."],["dc.description.sponsorship","Federal Ministry of Education and Research, Germany [01KG1409]"],["dc.identifier.doi","10.1097/j.pain.0000000000000640"],["dc.identifier.isi","000386015500006"],["dc.identifier.pmid","27257858"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39339"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1872-6623"],["dc.relation.issn","0304-3959"],["dc.title","Back schools for the treatment of chronic low back pain: possibility of benefit but no convincing evidence after 47 years of research-systematic review and meta-analysis"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]Details DOI PMID PMC WOS2021Journal Article [["dc.bibliographiccitation.firstpage","774"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","EP Europace"],["dc.bibliographiccitation.lastpage","783"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Pelli, Ari"],["dc.contributor.author","Junttila, M Juhani"],["dc.contributor.author","Kenttä, Tuomas V"],["dc.contributor.author","Schlögl, Simon"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Malik, Marek"],["dc.contributor.author","Reichlin, Tobias"],["dc.contributor.author","Willems, Rik"],["dc.contributor.author","Vos, Marc A"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Velchev, Vasil"],["dc.contributor.authorgroup","the EU-CERT-ICD Study Investigators"],["dc.date.accessioned","2022-06-01T09:39:20Z"],["dc.date.available","2022-06-01T09:39:20Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Aim The association of standard 12-lead electrocardiogram (ECG) markers with benefits of the primary prophylactic implantable cardioverter-defibrillator (ICD) has not been determined in the contemporary era. We analysed traditional and novel ECG variables in a large prospective, controlled primary prophylactic ICD population to assess the predictive value of ECG in terms of ICD benefit. Methods and results Electrocardiograms from 1477 ICD patients and 700 control patients (EU-CERT-ICD; non-randomized, controlled, prospective multicentre study; ClinicalTrials.gov Identifier: NCT02064192), who met ICD implantation criteria but did not receive the device, were analysed. The primary outcome was all-cause mortality. In ICD patients, the co-primary outcome of first appropriate shock was used. Mean follow-up time was 2.4 ± 1.1 years to death and 2.3 ± 1.2 years to the first appropriate shock. Pathological Q waves were associated with decreased mortality in ICD patients [hazard ratio (HR) 0.54, 95% confidence interval (CI) 0.35–0.84; P < 0.01] and patients with pathological Q waves had significantly more benefit from ICD (HR 0.44, 95% CI 0.21–0.93; P = 0.03). QTc interval increase taken as a continuous variable was associated with both mortality and appropriate shock incidence, but commonly used cut-off values, were not statistically significantly associated with either of the outcomes. Conclusion Pathological Q waves were a strong ECG predictor of ICD benefit in primary prophylactic ICD patients. Excess mortality among Q wave patients seems to be due to arrhythmic death which can be prevented by ICD."],["dc.identifier.doi","10.1093/europace/euab260"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108449"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","1532-2092"],["dc.relation.issn","1099-5129"],["dc.title","Q waves are the strongest electrocardiographic variable associated with primary prophylactic implantable cardioverter-defibrillator benefit: a prospective multicentre study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI2019Journal Article [["dc.bibliographiccitation.firstpage","196"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Diabetes Care"],["dc.bibliographiccitation.lastpage","200"],["dc.bibliographiccitation.volume","43"],["dc.contributor.author","Junttila, M. Juhani"],["dc.contributor.author","Pelli, Ari"],["dc.contributor.author","Kenttä, Tuomas V."],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Willems, Rik"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Malik, Marek"],["dc.contributor.author","Vandenberk, Bert"],["dc.contributor.author","Vos, Marc A."],["dc.contributor.author","Schmidt, Georg"],["dc.contributor.author","Merkely, Bela"],["dc.contributor.author","Lubinski, Andrzej"],["dc.contributor.author","Svetlosak, Martin"],["dc.contributor.author","Braunschweig, Frieder"],["dc.contributor.author","Harden, Markus"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Huikuri, Heikki V."],["dc.contributor.author","Sticherling, Christian"],["dc.date.accessioned","2020-12-10T18:43:45Z"],["dc.date.available","2020-12-10T18:43:45Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.2337/dc19-1014"],["dc.identifier.eissn","1935-5548"],["dc.identifier.issn","0149-5992"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78224"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Appropriate Shocks and Mortality in Patients With Versus Without Diabetes With Prophylactic Implantable Cardioverter Defibrillators"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]Details DOI