Tetens, Jens

[["dc.bibliographiccitation.journal","Veterinary Medicine and Science"],["dc.contributor.author","Wiedemann, Isabel"],["dc.contributor.author","Krebs, Tony"],["dc.contributor.author","Momberg, Niklas"],["dc.contributor.author","Knorr, Christoph"],["dc.contributor.author","Tetens, Jens"],["dc.date.accessioned","2019-07-09T11:46:00Z"],["dc.date.available","2019-07-09T11:46:00Z"],["dc.date.issued","2018"],["dc.description.abstract","The multigene family of pregnancy-associated glycoproteins (PAGs) belongs to a group of aspartic proteases that are exclusively expressed by trophoblast cells in the placenta of even-toed ungulates. In Bovidae, 22 different PAG genes (boPAGs) with a wide range of temporal and spatial expression- and glycosylation patterns have been reported to date. In this study we describe the mRNA expression patterns using real-time quantitative PCR (qPCR) for selected modern (boPAG-1, -9, -21) and ancient bovine PAGs (boPAG-2, -8, -10, -11, - 12) in cotyledonary tissue. The highest mean expression was detected in boPAG-8 and lowest in boPAG-10 (P < 0.05). Furthermore, boPAG-8 and -11 were significantly greater expressed in early gestation compared with later pregnancy stages. The characterization of boPAG mRNA-expression levels gives important insights for further protein analyses which will be valuable information for the development of new pregnancy detection systems."],["dc.identifier.doi","10.1002/vms3.123"],["dc.identifier.pmid","30265452"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15375"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59360"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","2053-1095"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","630"],["dc.title","mRNA expression profiling in cotyledons reveals significant up-regulation of the two bovine pregnancy-associated glycoprotein genes boPAG-8 and boPAG-11 in early gestation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","6095"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Felkel, Sabine"],["dc.contributor.author","Vogl, Claus"],["dc.contributor.author","Rigler, Doris"],["dc.contributor.author","Dobretsberger, Viktoria"],["dc.contributor.author","Chowdhary, Bhanu P."],["dc.contributor.author","Distl, Ottmar"],["dc.contributor.author","Fries, Ruedi"],["dc.contributor.author","Jagannathan, Vidhya"],["dc.contributor.author","Janečka, Jan E."],["dc.contributor.author","Leeb, Tosso"],["dc.contributor.author","Lindgren, Gabriella"],["dc.contributor.author","McCue, Molly"],["dc.contributor.author","Metzger, Julia"],["dc.contributor.author","Neuditschko, Markus"],["dc.contributor.author","Rattei, Thomas"],["dc.contributor.author","Raudsepp, Terje"],["dc.contributor.author","Rieder, Stefan"],["dc.contributor.author","Rubin, Carl-Johan"],["dc.contributor.author","Schaefer, Robert"],["dc.contributor.author","Schlötterer, Christian"],["dc.contributor.author","Thaller, Georg"],["dc.contributor.author","Tetens, Jens"],["dc.contributor.author","Velie, Brandon"],["dc.contributor.author","Brem, Gottfried"],["dc.contributor.author","Wallner, Barbara"],["dc.date.accessioned","2019-07-09T11:51:39Z"],["dc.date.available","2019-07-09T11:51:39Z"],["dc.date.issued","2019"],["dc.description.abstract","Analysis of the Y chromosome is the best-established way to reconstruct paternal family history in humans. Here, we applied fine-scaled Y-chromosomal haplotyping in horses with biallelic markers and demonstrate the potential of our approach to address the ancestry of sire lines. We de novo assembled a draft reference of the male-specific region of the Y chromosome from Illumina short reads and then screened 5.8 million basepairs for variants in 130 specimens from intensively selected and rural breeds and nine Przewalski's horses. Among domestic horses we confirmed the predominance of a young'crown haplogroup' in Central European and North American breeds. Within the crown, we distinguished 58 haplotypes based on 211 variants, forming three major haplogroups. In addition to two previously characterised haplogroups, one observed in Arabian/Coldblooded and the other in Turkoman/Thoroughbred horses, we uncovered a third haplogroup containing Iberian lines and a North African Barb Horse. In a genealogical showcase, we distinguished the patrilines of the three English Thoroughbred founder stallions and resolved a historic controversy over the parentage of the horse 'Galopin', born in 1872. We observed two nearly instantaneous radiations in the history of Central and Northern European Y-chromosomal lineages that both occurred after domestication 5,500 years ago."],["dc.identifier.doi","10.1038/s41598-019-42640-w"],["dc.identifier.pmid","30988347"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16162"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59981"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.subject.ddc","630"],["dc.title","The horse Y chromosome as an informative marker for tracing sire lines"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","100101"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Veterinary and Animal Science"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Diers, S."],["dc.contributor.author","Heise, J."],["dc.contributor.author","Krebs, T."],["dc.contributor.author","Groenewold, J."],["dc.contributor.author","Tetens, J."],["dc.date.accessioned","2020-05-28T13:05:54Z"],["dc.date.accessioned","2021-10-27T13:20:22Z"],["dc.date.available","2020-05-28T13:05:54Z"],["dc.date.available","2021-10-27T13:20:22Z"],["dc.date.issued","2020"],["dc.description.abstract","The aim of this study was to analyze possible effects of semen type (conventional vs. female sexed) and calf sex on fertility and production traits. For this purpose, field data of German Holstein heifers in Lower Saxony were evaluated. Sexed semen was mainly used for first insemination. 87.0% female calves were born from sexed semen, while 52.7% female calves were born from conventional semen. Heifers inseminated with sexed semen were on average 43 to 48 days younger at their first calving than heifers inseminated with conventional semen. Calf sex had an influence on the average calving ease and the dystocia rates. Male calves showed higher calving ease scores and caused a higher risk for dystocia than female calves. The semen type had no influence on these characteristics. Within the same calf sex, sexed semen had only minor effects on most traits, except for stillbirth rates: the stillbirth rate for male calves from female sexed semen was 30.6%, which was 2.86 times the stillbirth rate of male calves from conventional semen, possibly due to trisomies. Sexed semen played only a minor role for production traits in first lactations. The extrapolated 305-day milk yield was 200 kg lower for first calf heifers, which were inseminated with sexed semen compared to heifers inseminated with conventional semen. Fat and protein yield were 6 kg to 8 kg lower after use of sexed semen. Animals with female offspring from sexed semen showed higher survival rates than the other groups."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2020"],["dc.identifier.doi","10.1016/j.vas.2020.100101"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17349"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/91959"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.issn","2451-943X"],["dc.relation.orgunit","Department für Nutztierwissenschaften"],["dc.relation.orgunit","Fakultät für Agrarwissenschaften"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject","Sexed semen; Calf sex; Heifer; Stillbirth"],["dc.subject.ddc","630"],["dc.title","Effect of sexed semen on different production and functional traits in German Holsteins"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]