Wu, Shining

[["dc.bibliographiccitation.artnumber","PII S1388-2457(01)00726-X"],["dc.bibliographiccitation.firstpage","265"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Neurophysiology"],["dc.bibliographiccitation.lastpage","269"],["dc.bibliographiccitation.volume","113"],["dc.contributor.author","Sommer, M"],["dc.contributor.author","Wu, T"],["dc.contributor.author","Tergau, Frithjof"],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2021-06-01T10:50:21Z"],["dc.date.available","2021-06-01T10:50:21Z"],["dc.date.issued","2002"],["dc.description.abstract","Objectives: Repetitive transcranial magnetic stimulation (rTMS) can modify cortical excitability and is widely used for clinical and research purposes. We sought to determine the intra- and interindividual variability of its effects on motor cortex excitability, and whether repeated paired-pulses yield less variability than repeated single-pulses. Methods: We investigated rTMS over the left motor cortex of 6 healthy subjects and recorded motor evoked potentials (MEPs) from the right abductor digiti minimi muscle, Eighty single suprathreshold stimuli or conditioning-test pairs of stimuli were delivered at 2 Hz frequency. The pairs consisted of a subthreshold pulse followed by a suprathreshold pulse after 2, 5 or 10 ms, In each subject we studied all types of rTMS 5 times on separate days. Single suprathreshold pulses at 0.17 Hz preceded rTMS for baseline determination. Results: The day-to-day variability of MEPs during either type of rTMS was small compared to the subject-to-subject variability. MEPs increased during all types of rTMS except for interstimulus interval (ISI) 2 ms. Paired-pulses yielded less variability than single-pulse rTMS. Conclusions: Motor responses to rTMS show a high interindividual, but a low intraindividual variability. Repeated paired-pulses yield less variability than repeated single-pulses. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/S1388-2457(01)00726-X"],["dc.identifier.isi","000174689500009"],["dc.identifier.pmid","11856631"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86627"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Sci Ireland Ltd"],["dc.relation.issn","1388-2457"],["dc.title","Intra- and interindividual variability of motor responses to repetitive transcranial magnetic stimulation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]