Hülsmann, Michael

[["dc.bibliographiccitation.firstpage","271"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Oral Science"],["dc.bibliographiccitation.lastpage","274"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Baxter, Steffi"],["dc.contributor.author","Schöler, Christian"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Hülsmann, Michael"],["dc.date.accessioned","2020-11-05T14:51:39Z"],["dc.date.available","2020-11-05T14:51:39Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.2334/josnusd.19-0100"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17519"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/68291"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-352.3"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1880-4926"],["dc.relation.issn","1343-4934"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Sensitivity of conventional radiographs and cone-beam computed tomography in detecting the remaining root-canal filling material"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","785"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuron"],["dc.bibliographiccitation.lastpage","796"],["dc.bibliographiccitation.volume","40"],["dc.contributor.author","Gomeza, J."],["dc.contributor.author","Hulsmann, S."],["dc.contributor.author","Ohno, K."],["dc.contributor.author","Eulenburg, V."],["dc.contributor.author","Szoke, K."],["dc.contributor.author","Richter, D."],["dc.contributor.author","Betz, Heinrich"],["dc.date.accessioned","2018-11-07T10:34:45Z"],["dc.date.available","2018-11-07T10:34:45Z"],["dc.date.issued","2003"],["dc.description.abstract","The glycine transporter subtype 1 (GIyT1) is widely expressed in astroglial cells throughout the mammalian central nervous system and has been implicated in the regulation of N-methyl-D-aspartate (NMDA) receptor activity. Newborn mice deficient in GIyT1 are anatomically normal but show severe motor and respiratory deficits and die during the first postnatal day. In brainstem slices from GIyT1-deficient mice, in vitro respiratory activity is strikingly reduced but normalized by the glycine receptor (GlyR) antagonist strychnine. Conversely, glycine or the GIyT1 inhibitor sarcosine suppress respiratory activity in slices from wild-type mice. Thus, during early postnatal life, GIyT1 is essential for regulating glycine concentrations at inhibitory GlyRs, and GIyT1 deletion generates symptoms found in human glycine encephalopathy."],["dc.identifier.doi","10.1016/S0896-6273(03)00672-X"],["dc.identifier.isi","000186651200013"],["dc.identifier.pmid","14622582"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/11251"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44943"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0896-6273"],["dc.rights","CC BY-NC-ND 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/3.0"],["dc.title","Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in Glycinergic inhibition"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","180"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Oral Science"],["dc.bibliographiccitation.lastpage","183"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Baxter, Steffi"],["dc.contributor.author","Jablonski, Marie"],["dc.contributor.author","Hülsmann, Michael"],["dc.date.accessioned","2020-11-05T14:51:42Z"],["dc.date.available","2020-11-05T14:51:42Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.2334/josnusd.19-0113"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17520"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/68313"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-352.3"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1880-4926"],["dc.relation.issn","1343-4934"],["dc.relation.orgunit","Poliklinik für Präventive Zahnmedizin, Parodontologie und Kariologie"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Cone-beam-computed-tomography of the symmetry of root canal anatomy in mandibular incisors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","697"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Journal of Endodontics"],["dc.bibliographiccitation.lastpage","702"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Metzger, Zvi"],["dc.contributor.author","Teperovich, Ehud"],["dc.contributor.author","Cohen, Raphaela"],["dc.contributor.author","Zary, Raviv"],["dc.contributor.author","Paque, Frank"],["dc.contributor.author","Hülsmann, Michael"],["dc.date.accessioned","2018-11-07T08:44:35Z"],["dc.date.available","2018-11-07T08:44:35Z"],["dc.date.issued","2010"],["dc.description.abstract","Aim: The aim of this study was to evaluate the cleaning ability of the Self-Adjusting File (SAF) system in terms of removal of debris and smear layer. Methodology: Root canal preparations were performed in 20 root canals using an SAF operated with a continuous irrigation device. The glide path was initially established using a size 20 K-file followed by the SAF file that was operated in the root canal via a vibrating motion for a total of 4 minutes. Sodium hypochlorite (3%) and EDTA (17%) were used as continuous irrigants and were alternated every minute during this initial 4-minute period. This was followed by a 30-second rinse using EDTA applied through a nonactivated SAF and a final flush with sodium hypochlorite. The roots were split longitudinally and subjected to scanning electron microscopy (SEM). The presence of debris and a smear layer in the coronal, middle, and apical thirds of the canal were evaluated through the analysis of the SEM images using five-score evaluation systems based on reference photographs. Results: The SAF operation with continuous irrigation, using alternating irrigants, resulted in root canal walls that were free of debris in all thirds of the canal in all (100%) of the samples. In addition, smear layer free surfaces were observed in 100% and 80% of the coronal and middle thirds of the canal, respectively. In the apical third of the canal, smear layer free surfaces were found in 65% of the root canals. Conclusions: The operation of the SAF system with continuous irrigation coupled with alternating sodium hypochlorite and EDTA treatment resulted in a clean and mostly smear layer free dentinal surface in all parts of the root canal. (J Endod 2010;36:697-702)"],["dc.identifier.doi","10.1016/j.joen.2009.12.037"],["dc.identifier.isi","000276577800021"],["dc.identifier.pmid","20307746"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6188"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20233"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0099-2399"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","The Self-adjusting File (SAF). Part 3: Removal of Debris and Smear Layer-A Scanning Electron Microscope Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4750"],["dc.bibliographiccitation.issue","16"],["dc.bibliographiccitation.journal","Materials"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Hülsmann, Michael"],["dc.contributor.author","Beckmann, Christoph"],["dc.contributor.author","Baxter, Steffi"],["dc.date.accessioned","2021-10-01T09:58:28Z"],["dc.date.available","2021-10-01T09:58:28Z"],["dc.date.issued","2021"],["dc.description.abstract","Chemomechanical preparation of the root canal system is considered to be the most important part of root canal treatment, including both mechanical removal of tissue remnants and dentine chips, and chemical elimination of biofilm and microorganisms. A number of different solutions and agitation techniques have been proposed for that purpose. It was the aim of the present study to investigate whether root canal cleanliness can be improved by using a hydroxyapatite nanoparticle-containing solution with and without sonic or ultrasonic agitation. Seventy-four single-rooted teeth were divided into four experimental groups (n = 15) and two control groups (n = 7). All teeth were split longitudinally and a groove and three holes were cut into the root canal wall and filled with dentinal debris. Final irrigation was performed using sodium hypochlorite or a hydroxyapatite nanoparticle-containing solution (Vector polish) activated with a sonically or an ultrasonically driven endodontic file. Two calibrated investigators rated the remaining debris using a four-score scale. The results were analyzed using a non-parametric test with α < 0.05. Sonic and ultrasonic irrigation with sodium hypochlorite cleaned the grooves and holes well from debris. The hydroxyapatite nanoparticles activated by a sonic file cleaned grooves and holes equally well. Ultrasonically activated nanoparticles performance was clearly inferior. The syringe control-group left large amounts of debris in grooves and holes. The use of the hydroxyapatite nanoparticles used in this study did not improve removal of debris."],["dc.description.abstract","Chemomechanical preparation of the root canal system is considered to be the most important part of root canal treatment, including both mechanical removal of tissue remnants and dentine chips, and chemical elimination of biofilm and microorganisms. A number of different solutions and agitation techniques have been proposed for that purpose. It was the aim of the present study to investigate whether root canal cleanliness can be improved by using a hydroxyapatite nanoparticle-containing solution with and without sonic or ultrasonic agitation. Seventy-four single-rooted teeth were divided into four experimental groups (n = 15) and two control groups (n = 7). All teeth were split longitudinally and a groove and three holes were cut into the root canal wall and filled with dentinal debris. Final irrigation was performed using sodium hypochlorite or a hydroxyapatite nanoparticle-containing solution (Vector polish) activated with a sonically or an ultrasonically driven endodontic file. Two calibrated investigators rated the remaining debris using a four-score scale. The results were analyzed using a non-parametric test with α < 0.05. Sonic and ultrasonic irrigation with sodium hypochlorite cleaned the grooves and holes well from debris. The hydroxyapatite nanoparticles activated by a sonic file cleaned grooves and holes equally well. Ultrasonically activated nanoparticles performance was clearly inferior. The syringe control-group left large amounts of debris in grooves and holes. The use of the hydroxyapatite nanoparticles used in this study did not improve removal of debris."],["dc.identifier.doi","10.3390/ma14164750"],["dc.identifier.pii","ma14164750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/90068"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-469"],["dc.publisher","MDPI"],["dc.relation.eissn","1996-1944"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Debris Removal Using a Hydroxyapatite Nanoparticle-Containing Solution (Vector Polish) with Sonic or Ultrasonic Agitation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]